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acute pancreatitis review

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https://www.readbyqxmd.com/read/29777841/acute-ischemic-pancreatitis-secondary-to-aortic-dissection
#1
Rong Wang, Jun-Ming Zhu, Rui-Dong Qi, Yong-Min Liu, Jun Zheng, Nan Zhang, Li-Zhong Sun
OBJECTIVE: Acute ischemic pancreatitis secondary to aortic dissection is very rare with an unclarified mechanism. We retrospectively reviewed six such cases in our center and present their outcomes herein. MATERIAL AND METHODS: Between February 2009 and April 2017, six patients (male=2, female=4; mean age, 58 ± 8, range 47-70) years) with acute aortic dissection associated with pancreatitis were admitted to our center. There were three type A and three type B dissections...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29777831/microcystis-bloom-containing-microcystin-lr-induces-type-2-diabetes-mellitus
#2
Qiong Zhang, Wendi Qin, Liuyan Yang, Jing An, Xuxiang Zhang, Hao Hong, Lizhi Xu, Yaping Wang
Epidemiological data from Lake Taihu showed significantly higher incidences of type 2 diabetes mellitus (T2DM) than in other areas of China. This may be related to the occurrence of a Microcystis bloom in Lake Taihu in the summer and autumn every year. The objective of this study is to investigate whether the contaminated water from the Microcystis bloom and the derivative pollutant microcystin-LR (MC-LR) can explain the higher incidences of T2DM. Healthy male mice were fed with water from different regions of Lake Taihu, and were either acutely or chronically exposed to MC-LR through oral administration or intraperitoneal injection...
May 16, 2018: Toxicology Letters
https://www.readbyqxmd.com/read/29774182/spleen-and-splenic-vascular-involvement-in-acute-pancreatitis-an-mri-study
#3
Chao-Lian Xie, Mao Zhang, Yong Chen, Ran Hu, Meng-Yue Tang, Tian-Wu Chen, Hua-Dan Xue, Zheng-Yu Jin, Xiao-Ming Zhang
Background: To investigate the spleen and splenic vascular involvement in acute pancreatitis (AP) and their correlations with the severity of AP using magnetic resonance imaging (MRI). Methods: MRI of 239 patients with AP was retrospectively reviewed to assess splenic and splenic vascular complications, and the severity of AP. The severity of AP was graded by the MRI severity index (MRSI) and the New Revised Classification of AP 2012. The intravoxel incoherent motion (IVIM) parameters (D, D*, and f) of spleen were measured...
April 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29770308/allo-and-auto-percutaneous-intra-portal-pancreatic-islet-transplantation-pipit-for-diabetes-cure-and-prevention-the-role-of-imaging-and-interventional-radiology
#4
REVIEW
Massimo Venturini, Claudio Sallemi, Paolo Marra, Anna Palmisano, Giulia Agostini, Carolina Lanza, Gianpaolo Balzano, Massimo Falconi, Antonio Secchi, Paolo Fiorina, Lorenzo Piemonti, Paola Maffi, Antonio Esposito, Francesco De Cobelli, Alessandro Del Maschio
Although the life expectancy of patients with type 1 diabetes mellitus (T1DM) has improved since the introduction of insulin therapy, the acute life-threatening and long-term complications from diabetes mellitus are significant causes of both mortality and morbidity. Percutaneous intra-portal pancreatic islet transplantation (PIPIT) is a minimally invasive, repeatable procedure which allows a β-cell replacement therapy through a liver islet engraftment, leading to insulin release and glycaemic control restoration in patients with diabetes...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29757718/us-of-right-upper-quadrant-pain-in-the-emergency-department-diagnosing-beyond-gallbladder-and-biliary-disease
#5
Gayatri Joshi, Kevin A Crawford, Tarek N Hanna, Keith D Herr, Nirvikar Dahiya, Christine O Menias
Acute cholecystitis is the most common diagnosable cause for right upper quadrant abdominal (RUQ) pain in patients who present to the emergency department (ED). However, over one-third of patients initially thought to have acute cholecystitis actually have RUQ pain attributable to other causes. Ultrasonography (US) is the primary imaging modality of choice for initial imaging assessment and serves as a fast, cost-effective, and dynamic modality to provide a definitive diagnosis or a considerably narrowed list of differential possibilities...
May 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29751784/henoch-sch%C3%A3-nlein-purpura-with-acute-pancreatitis-analysis-of-13-cases
#6
Qin Zhang, Qi Guo, Ming Gui, Zhenhua Ren, Bo Hu, Ling Lu, Fang Deng
BACKGROUND: Henoch-Schönlein purpura is a common small vessel vasculitis in children. Acute pancreatitis rarely presents as a complication of Henoch-Schönlein purpura and has not been well characterized. METHODS: We retrospectively reviewed 13 cases of Henoch-Schönlein purpura with acute pancreatitis among 3212 patients who attended our hospital between January 2003 and June 2016 and analyzed their clinical characteristics, laboratory findings, imaging findings, treatment and overall prognosis...
May 11, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29747233/comparison-of-endoscopic-and-percutaneous-drainage-of-symptomatic-necrotic-collections-in-acute-necrotizing-pancreatitis
#7
Shanan Woo, Ryan Walklin, Travis Ackermann, Sheng Wei Lo, Hamish Shilton, Charles Pilgrim, Peter Evans, James Burnes, Daniel Croagh
INTRODUCTION: Primary endoscopic and percutaneous drainage for pancreatic necrotic collections is increasingly used. We aim to compare the relative effectiveness of both modalities in reducing the duration and severity of illness by measuring their effects on systemic inflammatory response syndrome (SIRS). METHODS: We retrospectively reviewed all cases of endoscopic and percutaneous drainage for pancreatic necrotic collections performed in 2011-2016 at two hospitals...
May 10, 2018: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29746344/nutritional-considerations-in-pediatric-pancreatitis-a-position-paper-from-the-naspghan-pancreas-committee-espghan-pancreas-working-group
#8
Maisam Abu-El-Haija, Aliye Uc, Steven L Werlin, A Jay Freeman, Miglena Georgieva, Danijela Jojkić - Pavkov, Daina Kalnins, Brigitte Kochavi, Bart G P Koot, Stephanie Van Biervliet, Jaroslaw Walkowiak, Michael Wilschanski, Veronique D Morinville
OBJECTIVES: Wide variations exist in how physicians manage the nutritional aspects of children affected by acute pancreatitis (AP), acute recurrent pancreatitis (ARP) and chronic (CP) pancreatitis. Better consensus for optimal management is needed. METHODS: This consensus statement on nutrition in pediatric pancreatic diseases was developed through a joint ESPGHAN-NASPGHAN working group that performed an evidence-based search of the literature on nutrition in AP, ARP, and CP with a focus on pediatrics...
May 8, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29745912/clinical-case-report-on-acute-pancreatitis-with-concomitant-t2dm-and-hypertriglyceridemia
#9
T Magradze, E Shelestova
Authors present a clinical case review of a 46-years-old, otherwise healthy female patient, presented with acute abdominal pain. Examination and full work-up established a diagnosis of acute pancreatitis, T2DM and hypertriglyceridemia; based on family history, inherited hypertriglyceridemia was suspected. Elevated TG values associated with diabetes dramatically increase the risk of developing MI. Subsequent to the pancreatitis treatment protocol completion, the patient has fully recovered from acute pancreatitis...
April 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29743979/mesenchymal-stromal-cell-therapy-for-pancreatitis-a-systematic-review
#10
REVIEW
Sara M Ahmed, Mahmoud Morsi, Nehal I Ghoneim, Mohamed M Abdel-Daim, Nagwa El-Badri
Background: Based on animal studies, adult mesenchymal stromal cells (MSCs) are promising for the treatment of pancreatitis. However, the best type of this form of cell therapy and its mechanism of action remain unclear. Methods: We searched the PubMed, Web of Science, Scopus, Google Scholar, and Clinical Trials.gov websites for studies using MSCs as a therapy for both acute and chronic pancreatitis published until September 2017. Results: We identified 276 publications; of these publications, 18 met our inclusion criteria...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29732686/ringer-s-lactate-vs-normal-saline-in-acute-pancreatitis-a-systematic-review-and-meta-analysis
#11
Umair Iqbal, Hafsa Anwar, Melissa Scribani
INTRODUCTION: Acute Pancreatitis (AP) is one of the most common causes of hospitalization in the United States. Aggressive intravenous hydration with crystalloids is the first step in management, and is associated with improved survival. Guidelines are unclear regarding the choice of crystalloids. Normal saline (NS) is most commonly used, but recent studies have shown Ringer's lactate (RL) to be associated with better outcomes. METHODS: A comprehensive literature review was conducted by searching the Embase, MEDLINE, Pubmed, and Google Scholar databases through December 2017 to identify all studies that compared the use of NS with RL for the management of acute pancreatitis...
May 7, 2018: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29722597/positive-predictive-value-of-acute-and-chronic-pancreatitis-diagnoses-in-the-danish-national-patient-registry-a-validation-study
#12
Jakob Kirkegård, Marie R Mortensen, Ida R Johannsen, Frank V Mortensen, Deirdre Cronin-Fenton
AIMS: To examine the validity of the diagnoses of acute and chronic pancreatitis registered in the Danish National Patient Registry. METHODS: We identified all patients in the Danish National Patient Registry admitted to two Danish hospitals with acute or chronic pancreatitis from 1996 to 2013. From this population, we randomly sampled 100 patients with acute pancreatitis and 100 patients with chronic pancreatitis. For each cohort, we computed the positive predictive values and associated 95% confidence intervals (CIs) for the discharge diagnosis of acute or chronic pancreatitis using medical records as the gold standard...
May 1, 2018: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29720098/tigecycline-induced-acute-pancreatitis-in-a-renal-transplant-patient-a-case-report-and-literature-review
#13
Jinwen Lin, Rending Wang, Jianghua Chen
BACKGROUND: The purpose of this case report is to increase the awareness of tigecycline-induced pancreatitis specifically in renal transplant patients predisposed to the condition. CASE PRESENTATION: A 48-year-old woman developed a donor-derived infection after kidney transplantation, resulting in a ruptured graft renal artery, followed by peritoneal drainage, blood and urine culture infections. Due to multiple drug resistance Acinetobacter baumannii cultured from the preservation fluid and blood, she was treated with tigecycline at the 8th post-transplant day combined with other antibiotics...
May 2, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29719210/cell-encapsulation-overcoming-barriers-in-cell-transplantation-in-diabetes-and-beyond
#14
Marco Farina, Jenolyn F Alexander, Usha Thekkedath, Mauro Ferrari, Alessandro Grattoni
Cell-based therapy is emerging as a promising strategy for treating a wide range of human diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and several types of cancer. Pancreatic islets, blood cells, hepatocytes, and stem cells are among the many cell types currently used for this strategy. The encapsulation of these "therapeutic" cells is under intense investigation to not only prevent immune rejection but also provide a controlled and supportive environment so they can function effectively...
April 29, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29716451/pancreaticopleural-fistula-a-rare-cause-of-pleural-empyema
#15
Wies Vanderbruggen, Vicky Dhooghe, Bart Bracke, Vera Hartman, Geert Roeyen, Dirk Ysebaert, Paul Van Schil, Thiery Chapelle
AIM: Pancreaticopleural fistula (PPF) is a rare complication of acute or chronic pancreatitis. When the pancreatic duct disrupts, pancreatic fluid may leak into the retroperitoneum and fistulate into the pleural cavity. Patients usually present with thoracic complaints, making it hard to suspect an abdominal etiology. Although PPF is uncommon, one must consider this diagnosis in patients with thoracic complaints and a history of alcohol abuse or pancreatitis. METHODS: We present an illustrative case and review of the literature on PPF...
May 2, 2018: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29713449/sclerosing-encapsulating-peritonitis-presenting-as-acute-on-chronic-small-bowel-obstruction-in-a-patient-with-history-of-peritoneal-carcinomatosis
#16
Roy Hajjar, Éric Debroux, Carole Richard, Marylène Plasse, Rasmy Loungnarath
Sclerosing encapsulating peritonitis (SEP) is a whitish fibrous envelope that encapsulates intra-abdominal peritonealized organs. Although it pathophysiology is not well understood, several possible causes have been reported in the literature, including peritoneal dialysis, past abdominal surgeries, peritonitis, beta-blockers and peritoneal carcinomatosis (PC). Some idiopathic cases, with no apparent causes, were described. We present a SEP case in a 43-year-old woman with a surgical history of pancreatic and liver resection for metastatic pseudopapillary pancreatic tumor, followed by several peritonectomies for PC...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29707526/combination-immunotherapy-approaches-for-pancreatic-cancer-treatment
#17
REVIEW
Xianliang Cheng, Gang Zhao, Yunqi Zhao
Pancreatic ductal adenocarcinoma is a lethal malignant disease with a very low medium survival. Currently, metastatic pancreatic cancer poorly responds to conventional treatments and exhibits an acute resistance to most chemotherapy. Few approaches have been shown to be effective for metastatic pancreatic cancer treatment. Novel therapeutic approaches to treat patients with pancreatic adenocarcinoma are in great demand. Last decades, immunotherapies have been evaluated in clinical trials and received great success in many types of cancers...
2018: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29703106/recent-trends-and-perspectives-in-enzyme-based-biosensor-development-for-the-screening-of-triglycerides-a-comprehensive-review
#18
Vinita Hooda, Anjum Gahlaut, Ashish Gothwal, Vikas Hooda
Clinical manifestations of the elevated plasma triacylglycerol (TG) include a greater prevalence of atherosclerotic heart disease, acute pancreatitis, diabetes mellitus, hypertension, and ischemic vascular disease. Hence, these significant health troubles have attracted scientific attention for the precise detection of TG in biological samples. Numerous techniques have been employed to quantify TG over many decades, but biosensors hold the leading position owing to their superior traits such as highly specific recognition for target molecules, accuracy, minituarization, small sample requirement and rapid response...
April 27, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29702529/the-interface-of-pancreatic-cancer-with-diabetes-obesity-and-inflammation-research-gaps-and-opportunities-summary-of-a-national-institute-of-diabetes-and-digestive-and-kidney-diseases-workshop
#19
James L Abbruzzese, Dana K Andersen, Carl A K Borrebaeck, Suresh T Chari, Eithne Costello, Zobeida Cruz-Monserrate, Guido Eibl, Edgar G Engleman, William E Fisher, Aida Habtezion, Seung K Kim, Murray Korc, Craig Logsdon, Costas A Lyssiotis, Stephen J Pandol, Anil Rustgi, Bruce M Wolfe, Lei Zheng, Alvin C Powers
A workshop on "The Interface of Pancreatic Cancer with Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities" was held by the National Institute of Diabetes and Digestive and Kidney Diseases on October 12, 2017. The purpose of the workshop was to explore the relationship and possible mechanisms of the increased risk of pancreatic ductal adenocarcinoma (PDAC) related to diabetes, the role of altered intracellular energy metabolism in PDAC, the mechanisms and biomarkers of diabetes caused by PDAC, the mechanisms of the increased risk of PDAC associated with obesity, and the role of inflammatory events and mediators as contributing causes of the development of PDAC...
May 2018: Pancreas
https://www.readbyqxmd.com/read/29692941/pancreatic-hydatid-cyst-causing-acute-pancreatitis-a-case-report-and-literature-review
#20
Bayan Alsaid, Maryam Alhimyar, Fadi Rayya
Hydatidosis is a public health problem in endemic countries. Hydatid cysts are located usually in the liver and the lungs. Primary pancreatic hydatid cyst is in unusual location and rarely causes acute pancreatitis. In this paper, we report a case of a 34-year-old man who admitted with recurrent acute pancreatitis. Following the preoperation investigations, the primary impression was a pancreatic pseudocyst. During surgery, a primary hydatid cyst was detected in the pancreas measuring 35 × 20 × 15 cm. The treatment consisted of evacuation and external draining of the cyst...
2018: Case Reports in Surgery
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