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Lamellar keratoplasty

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https://www.readbyqxmd.com/read/28914632/stepwise-guided-photorefractive-keratectomy-in-treatment-of-irregular-astigmatism-after-penetrating-keratoplasty-and-deep-anterior-lamellar-keratoplasty
#1
Nir Sorkin, Adi Einan-Lifshitz, Sagi Abelson, Tanguy Boutin, Mahmood Showail, Armand Borovik, Zach Ashkenazy, Clara C Chan, David S Rootman
PURPOSE: To report the outcome of stepwise ablation using topography-guided photorefractive keratectomy to treat irregular astigmatism after either penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK). METHODS: This is a retrospective, interventional analysis including patients with irregular astigmatism after either PKP or DALK, who underwent topography-guided photorefractive keratectomy. The entire cohort was analyzed, as well as the PKP and DALK groups separately...
September 12, 2017: Cornea
https://www.readbyqxmd.com/read/28880340/topography-guided-photorefractive-keratectomy-in-the-treatment-of-corneal-scarring
#2
Nir Sorkin, Adi Einan-Lifshitz, Tanguy Boutin, Mahmood Showail, Armand Borovik, Clara C Chan, David S Rootman
PURPOSE: To report the outcome of topography-guided photorefractive keratectomy (TG-PRK) in the treatment of patients with corneal scarring. METHODS: A retrospective, interventional case series including 6 eyes of 6 patients with corneal scarring and irregular astigmatism who underwent TG-PRK. The etiologies for scarring were: infectious corneal ulcers, foreign body trauma, LASIK flap buttonhole, and lamellar keratoplasties performed to correct corneal perforation secondary to corneal melting...
September 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28855517/cross-linked-decellularized-porcine-corneal-graft-for-treating-fungal-keratitis
#3
Yongliang Lin, Qinxiang Zheng, Shanshan Hua, Yongchun Meng, Wei Chen, Yifei Wang
This study aims to develop a cross-linked decellularized porcine corneal graft (cDPC) as a substitute for lamellar donor corneas and to evaluate the feasibility of using cDPC to treat fungal keratitis. The cDPC was prepared by decellularization, chemical crosslinking and γ-ray irradiation. Transparency, effectiveness of decellularization and biomechanical strength of cDPC were evaluated. The safety and efficacy of using cDPC to treat fungal keratitis were evaluated in the rabbit model. The transparency of cDPC was similar to that of a native porcine cornea (NPC), and no intact cells were observed in cDPC except for an insignificant amount of residual shrinking cellular nucleus...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28844326/-comparison-of-anatomic-and-functional-results-between-z6%C3%A2-femtosecond-laser-assisted-and-manual-trephination-in-deep-anterior-lamellar-keratoplasty-for-advanced-keratoconus-french-version
#4
A Blériot, E Martin, P Lebranchu, K Zimmerman, L Libeau, M Weber, B Vabres, I Orignac
The management of severe keratoconus requires corneal transplantation, for which the gold standard is deep anterior lamellar keratoplasty (DALK), preserving the healthy Descemet's membrane and endothelium. The safety and reproducibility of corneal cuts have been improved by the evolution of femtosecond lasers in refractive surgery, and femtosecond laser in DALK would seem to provide the same advantages over the manual method. In our retrospective study, we compare functional and anatomical results of femtosecond assisted DALK versus manual trephination DALK in patients with keratoconus in stage 4 of the Krumeich classification...
September 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28837528/minimizing-graft-preparation-failure-in-descemet-membrane-endothelial-keratoplasty
#5
Eitan Livny, Esther A Groeneveld-van Beek, Jessica T Lie, Kristin M Mangundap, Marieke Bruinsma, Rénuka S Birbal, Jacqueline van der Wees, Gerrit R J Melles
PURPOSE: To report the failure rate of 2 graft preparation techniques for Descemet membrane endothelial keratoplasty (DMEK) and to evaluate how to minimize graft preparation failure. METHODS: Retrospective, nonrandomized study at an eye bank specialized in graft preparation for lamellar keratoplasty. For 1416 donor corneas, the DMEK graft preparation failure rate was evaluated for 2 different techniques, technique I: "Standardized traditional technique" (n = 341) and technique II: "Standardized no-touch technique" (n = 933), and for grafts that were converted from technique II to technique I during preparation (n = 142)...
August 23, 2017: Cornea
https://www.readbyqxmd.com/read/28831627/gender-differences-in-keratoconus-keratoplasty-a-25-year-study-in-southern-brazil-and-global-perspective
#6
Otavio A Magalhaes, Samara B Marafon, Raissa C Ferreira
PURPOSE: To compare the characteristics and outcomes of male and female patients that underwent corneal transplantation for keratoconus (KC) in Southern Brazil and worldwide. METHODS: Retrospective longitudinal study that evaluated medical records of patients who were submitted to keratoplasty between August 1990 and September 2015 in two tertiary hospitals in the state of Rio Grande do Sul (Brazil) and review of the Medline and Embase database international literature...
August 22, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28830376/hydrophilic-intraocular-lens-opacification-after-posterior-lamellar-keratoplasty-a-material-analysis-with-special-reference-to-optical-quality-assessment
#7
Bert C Giers, Tamer Tandogan, Gerd U Auffarth, Chul Y Choi, Florian N Auerbach, Saadettin Sel, Christian Mayer, Ramin Khoramnia
BACKGROUND: Laboratory analysis and optical quality assessment of explanted hydrophilic intraocular lenses (IOLs) with clinically significant opacification after posterior lamellar keratoplasty (DMEK and DSAEK). METHODS: Thirteen opacified IOLs after posterior lamellar keratoplasty, 8 after descemet stripping automated endothelial keratoplasty (DSAEK), 3 after descemet membrane endothelial keratoplasty (DMEK) and 2 after both DSAEK and DMEK were analysed in our laboratory...
August 22, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28808586/quality-of-vision-after-deep-anterior-lamellar-keratoplasty-fluid-dissection-compared-to-penetrating-keratoplasty-for-the-treatment-of-keratoconus
#8
Islam Mahmoud Hamdi, Momen Mahmoud Hamdi
PURPOSE: To compare the visual quality of patients with keratoconus who underwent penetrating keratoplasty (PKP) or deep anterior lamellar keratoplasty (DALK) with fluid dissection. DESIGN: Cross-sectional, observational study. METHODS: Twelve eyes that underwent PKP (PKP group) were compared to 24 eyes that underwent DALK (DALK group) after complete removal of sutures and stability of refraction. Visual, refractive, corneal topographic, corneal aberrometry, and ocular aberrometry parameters were compared for both groups...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28801092/anterior-segment-optical-coherence-tomography-for-the-diagnosis-of-corneal-dystrophies-according-to-the-ic3d-classification
#9
REVIEW
Sebastian Siebelmann, Paula Scholz, Simon Sonnenschein, Björn Bachmann, Mario Matthaei, Claus Cursiefen, Ludwig M Heindl
Corneal dystrophies are categorized according to the International Committee for Classification of Corneal Dystrophies (IC3D) classification, and their treatment depends on the affected structures and layer of the cornea. Therefore, estimating the depth and extent of the morphological changes due to the specific dystrophy is crucial when deciding between different treatment options. Besides superficial laser treatments and penetrating keratoplasty, minimal invasive lamellar keratoplasties such as Descemet membrane endothelial keratoplasty), deep anterior lamellar keratoplasty, or Descemet stripping automated keratoplasty have become increasingly popular to exchange the specific opaque layers in dystrophic eyes...
August 8, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28777776/immunologic-rejection-episodes-after-deep-anterior-lamellar-keratoplasty-incidence-and-risk-factors
#10
Andres Gonzalez, Marianne O Price, Matthew T Feng, Christopher Lee, Juan G Arbelaez, Francis W Price
PURPOSE: To assess the rejection episode rate after deep anterior lamellar keratoplasty (DALK) and to identify associated risk factors. METHODS: This retrospective review of 251 primary DALK procedures performed by 14 surgeons at a single center between February 2008 and November 2015 evaluated the rejection episode rate and associated risk factors using Kaplan-Meier survival and proportional hazards analyses, which took the length of follow-up into consideration...
September 2017: Cornea
https://www.readbyqxmd.com/read/28777101/new-graft-insertion-device-for-descemet-stripping-automated-endothelial-keratoplasty
#11
Takeshi Soma, Shizuka Koh, Naoyuki Maeda, Kikuo Mitomo, Andrew J Quantock, Kohji Nishida
PURPOSE: Corneal endothelial dysfunction is a major indication for corneal graft surgery worldwide, and although surgical intervention through a range of posterior lamellar surgeries has proven to be hugely beneficial, challenges remain. This is especially so where the anterior chamber is relatively shallow, as is often the case in the Asian population, though not exclusively so. In this study, we introduce a new insertion device to deliver endothelial graft tissue for Descemet stripping automated endothelial keratoplasty (DSAEK)...
August 2, 2017: Cornea
https://www.readbyqxmd.com/read/28775086/tailored-lamellar-keratoplasty-a-new-technique
#12
Mohammad Solaimani, Seyed Ali Tabatabaei, Zahra Fallah Tafti
We present a new method for treating complicated corneal gaps among patients who have previously undergone radial keratotomy (RK).After complete healing of a fungal keratitis in a patient who has undergone RK, we removed the oedematous corneal sector and put anterior tailored segment of a corneal button previously used for Descemet stripping endothelial keratoplasty. The patient's best-corrected visual acuity reached to 20/20 6 months later. This technique will compensate for oedematous parts without putting a significant effect on other parts such as purse string sutures...
August 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28759902/-complications-of-dmekeratoplasty-avoid-recognize-and-treat
#13
Björn O Bachmann, Silvia A Schrittenlocher, Friederike Schaub, Sebastian Siebelmann, Mario Matthaei, Claus Cursiefen
Descemet membrane endothelial keratoplasty (DMEK) has evolved into a routine surgical procedure for posterior lamellar keratoplasty. After its introduction more than 10 years ago, several modifications in grafting technique and postoperative treatment regimen helped to improve its safety and reproducibility. Although DMEK offers faster and better improvements in visual acuity, as well as less graft rejections when compared to Descemet's stripping (automated) endothelial keratoplasty (DS[A]EK), difficulties when implementing this technique hamper the widespread use in many areas...
July 31, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28749898/recurrence-of-granular-corneal-dystrophy-type-1-after-phototherapeutic-keratectomy-lamellar-keratoplasty-and-penetrating-keratoplasty-in-a-single-population
#14
Darrell R Lewis, Marianne O Price, Matthew T Feng, Francis W Price
PURPOSE: To describe the recurrence of granular corneal dystrophy type 1 (GCD1) after penetrating keratoplasty (PKP), anterior lamellar keratoplasty (ALK), deep anterior lamellar keratoplasty (DALK), and phototherapeutic keratectomy (PTK) in a single population. The time required to achieve best-corrected visual acuity (BCVA) after each intervention was also analyzed. METHODS: Retrospective review of all patients with GCD1 from a single center between 1989 and 2016...
October 2017: Cornea
https://www.readbyqxmd.com/read/28730097/recurrence-of-keratoconus-after-deep-anterior-lamellar-keratoplasty-following-pregnancy
#15
Zisis Gatzioufas, Georgios D Panos, Evangelia Gkaragkani, Stylianos Georgoulas, Romesh Angunawela
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28688026/indications-and-graft-survival-analysis-in-optical-penetrating-keratoplasty-in-a-tertiary-care-center-in-north-india-a-5-year-study
#16
Sudesh Kumar Arya, Amit Raj, Ravi Kant Bamotra, Anubha Bhatti, Jyoti Deswal, Meenakshi Sindhu
PURPOSE: To study the indications and variables correlating with graft survival in optical penetrating keratoplasty in a tertiary care hospital in north India. PARTICIPANTS: All patients who underwent optical keratoplasty, except those undergoing lamellar grafts, tectonic grafts transplants and penetrating keratoplasty done for therapeutic purposes were included in the study. Patients with follow-up less than 2 years were excluded from the study. MATERIALS AND METHODS: Data were obtained by reviewing the records of 101 patients who underwent optical penetrating keratoplasty from 2008 to 2013 for various indications...
July 7, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28683485/-therapeutic-options-in-keratoconus
#17
Frederik Raiskup, Janine Lenk, Robert Herber, Zisis Gatzioufas, Eberhard Spörl
A recent epidemiology study revealed that prevalence of keratoconus was much higher than previously assumed. Therefore, it is no longer deemed an "orphan disease", as it has a relevant socioeconomic impact on the healthcare system. One of the most important risk factors for developing keratoconus is chronic eye rubbing which, apart from other known risk factors such as atopy or Down's syndrome, is the only modifiable factor. Informing the patient and offering behavior modifying therapies seems to be essential...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28683478/-emergency-keratoplasty-with-porcine-xenografts-in-necrotizing-keratitis
#18
Galyna I Drozhzhyna, Tetiana B Gaidamaka, Claus Cursiefen, Björn O Bachmann, Olena V Ivanovska, Viktor L Ostashevsky, Boris M Kogan, Volodymyr J Usov, Natalija V Pasyechnikova
Background The great shortage of donor material in Ukraine makes it necessary to find additional sources of transplant material. A possible suitable material are the porcine corneas, as they are similar in structure and biomechanical parameters to the human cornea. The purpose of our study was to analyze the results of therapeutic keratoplasty (KP) with keratoxenotransplants from cryolyophilized porcine corneas in patients with severe necrotizing keratitis. Methods A retrospective analysis of 32 xenotransplantations patients with severe necrotizing keratitis (17 lamellar, 6 stepped perforating, 4 perforating, 5 "biological coverage" according to Puchkovskaya) was completed...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28672072/-blue-bubble-technique-an-ab-interno-approach-for-descemet-separation-in-deep-anterior-lamellar-keratoplasty-using-trypan-blue-stained-viscoelastic-device
#19
Eitan Livny, Irit Bahar, Naama Hammel, Yoav Nahum
BACKGROUND: In this study, we examined a novel variant of 'big-bubble' deep anterior lamellar keratoplasty using trypan-blue-stained viscoelastic device for the creation of a pre-descemetic bubble. METHODS: Ten corneoscleral rims were mounted on an artificial anterior chamber (AC). The AC was filled with air through a limbal paracentesis. A Melles' triangulated spatula was inserted through the paracentesis, with its tip penetrating the AC, was then slightly retracted and pushed into the deep stroma above the roof of the paracentesis...
July 3, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28667581/intracameral-dexamethasone-injection-as-adjuvant-therapy-in-endothelial-immune-reaction-after-penetrating-and-posterior-lamellar-keratoplasty-a-retrospective-clinical-observation
#20
Miltiadis Fiorentzis, Arne Viestenz, Anja Viestenz, Berthold Seitz
INTRODUCTION: The aim of this observational study is to evaluate the effectiveness of an adjuvant intracameral corticosteroid injection (ICI) in cases of severe endothelial immune reaction (SEIR) (anterior chamber cells and flare, retrocorneal precipitates, Descemet's folds, and corneal edema) after penetrating keratoplasty and posterior lamellar keratoplasty. METHODS: In this retrospective study, 24 subjects treated between November 2011 and September 2014 were divided into two groups...
June 30, 2017: Advances in Therapy
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