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Lamellar keratoplasty

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https://www.readbyqxmd.com/read/29149876/impact-of-donor-graft-quality-on-deep-anterior-lamellar-keratoplasty-dalk
#1
Friederike Schaub, Philip Enders, Werner Adler, Björn O Bachmann, Claus Cursiefen, Ludwig M Heindl
BACKGROUND: To evaluate main features of donor tissue that may influence clinical outcome or complication rate after deep anterior lamellar keratoplasty (DALK). METHODS: Donor tissue parameters of 84 consecutive corneal donor grafts used for big-bubble DALK surgery between June 2011 and December 2014 in 84 eyes of 84 patients with disorders of anterior corneal stroma were correlated to clinical outcome parameters of recipient eyes 12 months after surgery and 3 months after total suture removal...
November 17, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29146479/visual-outcome-of-penetrating-keratoplasty-deep-anterior-lamellar-keratoplasty-and-descemet-membrane-endothelial-keratoplasty
#2
Clàudia Garrido, Genís Cardona, Josep L Güell, Jaume Pujol
PURPOSE: A single-center, cross-sectional study was designed to assess and compare objective and subjective quality of vision of patients intervened with penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK) and Descemet membrane endothelial keratoplasty (DMEK). METHODS: Forty-six patients previously intervened with PK (22 eyes), DALK (7 eyes) and DMEK (17 eyes) were recruited. Visual evaluation included spherical and cylindrical refraction, distance corrected visual acuity (DCVA), photopic contrast sensitivity (CS), optical quality, measured with the HD Analyzer (objective scattering index [OSI], MTF cut-off and Strehl ratio), and ocular and corneal aberrometry, measured with the KR-1W Wavefront Analyzer...
November 13, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/29133660/predescemetocele-a-distinct-clinical-entity
#3
Priya Narang, Amar Agarwal, Dhivya Ashok Kumar
The case report incorporates a Fourier-domain optical coherence tomography (OCT) examination for demonstration of the existence of pre-Descemet's layer (PDL; Dua's layer) overlying a descemetocele and demonstrates predescemetocele as a separate clinical entity. The prospective analysis was done in two cases that had descemetocele, and OCT demonstrated the presence of PDL over an unruptured descemetocele that offers resilience and can be treated with an elective deep anterior lamellar keratoplasty or a penetrating keratoplasty...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29133630/non-contact-lens-related-acanthamoeba-keratitis
#4
REVIEW
Prashant Garg, Paavan Kalra, Joveeta Joseph
The purpose of the study is to describe epidemiology, clinical features, diagnosis, and treatment of Acanthamoeba keratitis (AK) with special focus on the disease in nonusers of contact lenses (CLs). This study was a perspective based on authors' experience and review of published literature. AK accounts for 2% of microbiology-proven cases of keratitis. Trauma and exposure to contaminated water are the main predisposing factors for the disease. Association with CLs is seen only in small fraction of cases. Contrary to classical description experience in India suggests that out of proportion pain, ring infiltrate, and radial keratoneuritis are seen in less than a third of cases...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29132691/-practical-assessment-of-dsaek-in-the-management-of-endothelial-decompensation-following-penetrating-keratoplasty
#5
E Neiter, C Goetz, F Tortuyaux, A Ehrhardt, N Houmad, J-M Perone
PURPOSE: To report our anatomical and functional results as well as possible complications of the first six Descemet's stripping endothelial keratoplasties (DSAEK) performed in our department for endothelial decompensation after penetrating keratoplasty (PK) METHODS: This was a retrospective and observational monocentric study of six patients with DSAEK after prior PK between January 2015 and July 2016. The data collected were: demographic characteristics (age, sex), ophthalmological comorbidities, initial indication for PK, delay between PK and DSAEK...
November 11, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29118505/descemet-s-membrane-macroperforation-during-interface-irrigation-in-big-bubble-deep-anterior-lamellar-keratoplasty
#6
Mohammed Ziaei, Susan E Ormonde
This report describes the macroperforation of descemet's membrane (DM) during irrigation of the interface following successful removal of stromal tissue in big bubble (BB) deep anterior lamellar keratoplasty (DALK). A 42-year-old woman with keratoconus underwent a BB DALK procedure. After successful formation of Type 2 bubble and removal of stromal tissue, interface irrigation was performed to remove residual viscoelastic. This led to a macroperforation of DM, and the case was converted to penetrating keratoplasty...
September 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29118500/iridoplasty-of-fixed-dilated-pupil-urrets-zavalia-syndrome-after-deep-anterior-lamellar-keratoplasty
#7
Efthalia Ntora, Nikolaos Ziakas
A 38-year-old woman with advanced keratoconus initially developed Urrets-Zavalia Syndrome (UZS) in the left eye after deep anterior lamellar keratoplasty. During the uneventful surgery, a 7-mm-wide pupil unresponsive to light was noticed. On the first postoperative day, intraocular pressure (IOP) was elevated up to 45 mmHg with shallow anterior chamber (AC). A peripheral iridotomy in 2 o'clock position was conducted and a fixed combination of brinzolamide 1% and timolol 0.5% was administered topically. In the subsequent postoperative period, IOP was successfully reduced, but the patient reported severe photophobia, glare, and decreased vision...
September 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29095753/effect-of-suture-removal-on-refraction-and-graft-curvature-after-deep-anterior-lamellar-keratoplasty-in-patients-with-keratoconus
#8
Sepehr Feizi, Mohammad Ali Javadi, Nazanin Behnaz, Sadaf Fani-Hanife, Mohammad Reza Jafarinasab
PURPOSE: To evaluate the effect of suture removal on refraction and keratometry measurements after deep anterior lamellar keratoplasty (DALK). METHODS: This retrospective study enrolled 54 keratoconus-affected eyes that underwent DALK. A combined suturing technique consisting of a 16-bite single running and 8-bite interrupted 10-0 nylon sutures was used at the time of keratoplasty. Selective interrupted suture removal was performed in a subgroup of patients to reduce postkeratoplasty astigmatism...
October 31, 2017: Cornea
https://www.readbyqxmd.com/read/29095752/double-docking-technique-for-femtosecond-laser-assisted-deep-anterior-lamellar-keratoplasty
#9
Damien Guindolet, Diem T Nguyen, Ciara Bergin, Serge Doan, Isabelle Cochereau, Eric E Gabison
PURPOSE: To describe a new and safe surgical technique of deep anterior lamellar keratoplasty (DALK) using the femtosecond laser (FSL) and intraoperative optical coherence tomography (iOCT) for surgical management of corneal thinning and/or opacities. The technique was coined the double-docking procedure for DALK (DD-DALK). METHODS: FSL-integrated iOCT was used for direct visualization and calibration to perform precise anterior lamellar and side cuts for the removal of the anterior stroma...
October 31, 2017: Cornea
https://www.readbyqxmd.com/read/29066651/rescuing-the-host-descemet-s-membrane-in-full-thickness-traumatic-wound-dehiscence-in-deep-anterior-lamellar-keratoplasty-intraoperative-optical-coherence-tomography-ioct-guided-technique
#10
Manthan Hasmukhbhai Chaniyara, Rahul Bafna, Jayanand Urkude, Namrata Sharma
Optimal visual recovery following full-thickness traumatic wound dehiscence in a case of operated deep anterior lamellar keratoplasty (DALK) is rarely seen. Here we report a case of 22-year-old male patient presented to our casualty department with complaint of sudden-onset diminution of vision in his right eye following blunt trauma of 1 day duration. DALK had been performed 11 months ago for advanced keratoconus in the same eye. Best-corrected visual acuity (BCVA) in the right eye was hand movement close to face with accurate projection of rays and in the left eye was 20/20...
October 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29053558/in-vivo-confocal-microscopy-reveals-corneal-reinnervation-after-treatment-of-neurotrophic-keratopathy-with-corneal-neurotization
#11
Simon S M Fung, Joseph Catapano, Uri Elbaz, Ronald M Zuker, Gregory H Borschel, Asim Ali
PURPOSE: To document the presence and location of new sensory nerve fibers after corneal neurotization using in vivo confocal microscopy (IVCM) in 2 patients with neurotrophic keratopathy (NK). METHODS: Two patients with unilateral advanced NK received corneal neurotization to surgically reinnervate the cornea. IVCM was used to identify subbasal nerve fibers and document corneal reinnervation. In 1 patient (case 1), IVCM was performed before and after corneal neurotization; in the second patient (case 2), IVCM was performed after neurotization and corneal transplantation...
October 17, 2017: Cornea
https://www.readbyqxmd.com/read/29044073/type-2-big-bubble-deep-anterior-lamellar-keratoplasty-serial-anterior-segment-optical-coherence-tomography-documentation-showing-resolution-of-bubble-in-the-postoperative-period
#12
https://www.readbyqxmd.com/read/29040118/influence-of-socioeconomic-deprivation-on-visual-acuity-in-patients-undergoing-corneal-transplantation
#13
Scott J Robbie, Mark N A Jones, Daniel F P Larkin
PURPOSE: To determine whether there is an association between socioeconomic status and best-corrected visual acuity (BCVA) in patients undergoing corneal transplantation in the United Kingdom. METHODS: Retrospective cohort study of 4306 patients registered on the national United Kingdom Transplant Registry and undergoing penetrating keratoplasty, anterior lamellar keratoplasty, or endothelial keratoplasty in 2002, 2008, and 2013. Socioeconomic status was determined by applying a validated deprivation index to generate a score based on 5 categories...
October 13, 2017: Cornea
https://www.readbyqxmd.com/read/29023312/prediction-of-descemet-membrane-perforation-during-deep-anterior-lamellar-keratoplasty-in-patients-with-keratoconus-with-stromal-scar
#14
Mehmet Cuneyt Ozmen, Nilufer Yesilirmak, Bahri Aydin, Kubra Serbest Ceylanoglu, Hatice Tuba Atalay, Fikret Akata
OBJECTIVES: To report big-bubble deep anterior lamellar keratoplasty (DALK) in patients with keratoconus with corneal stromal scar, and to investigate factors that can influence intraoperative Descemet membrane (DM) perforation. METHODS: A retrospective study included patients with keratoconus with central stromal scar that underwent DALK using the big-bubble technique. Best spectacle-corrected visual acuity (BSCVA), keratometry, minimum corneal thickness (MCT), stromal scar depth, and endothelial cell density (ECD) were recorded...
October 11, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28991852/preparation-and-biomechanical-properties-of-an-acellular-porcine-corneal-stroma
#15
Qing Li, Hongmei Wang, Zhenye Dai, Yichen Cao, Chuanyu Jin
PURPOSE: To construct an acellular porcine corneal stroma (aPCS) as a human corneal stroma alternative and to further explore its biomechanical properties. METHODS: A combination of DNA-RNA enzymes and ultrasound technology was used to strip the native porcine corneal cells. The microstructure of aPCS was observed by H&E staining, DAPI staining, and α-Gal tests. The mechanical properties were detected by a tension machine. Cytotoxicity of aPCS was measured by the MTT assay...
November 2017: Cornea
https://www.readbyqxmd.com/read/28967073/microbubble-technique-in-failed-deep-anterior-lamellar-keratoplasty-2-year-outcomes
#16
Stefano Lippera, Giuseppe Pallotta, Piero Ferroni, Myrta Lippera, Leopoldo Spadea, Carlo Cagini
PURPOSE: To compare the long-term results of big-bubble technique and microbubble techniques to complete stroma dissection after failure of achieving a big-bubble. METHODS: A total of 35 eyes with keratoconus underwent lamellar keratoplasty with the big-bubble technique (15 eyes) or the microbubble technique (15 eyes). Conversion to penetrating keratoplasty was performed in 3 eyes of the big-bubble group and in 2 eyes of the microbubble group. Best-corrected visual acuity, corneal thickness, corneal astigmatism, and endothelial cell count were assessed preoperatively and at 12 and 24 months after surgery...
September 11, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28951784/intrastromal-corneal-ring-segments-for-astigmatism-correction-after-deep-anterior-lamellar-keratoplasty
#17
Júlio C D Arantes, Sandro Coscarelli, Paulo Ferrara, Luana P N Araújo, Marcos Ávila, Leonardo Torquetti
Background. To evaluate the change in corneal astigmatism after intrastromal corneal ring segment (ICRS) implantation in keratoconus patients with previous deep anterior lamellar keratoplasty (DALK). Design was a longitudinal, retrospective, interventional study. The study included 25 eyes of 24 patients with keratoconus who had DALK performed at least two years prior to ICRS implantation. All patients had a clear corneal graft with up to 8.00 D of corneal astigmatism and intolerance to contact lenses. The studied parameters were age, sex, corrected distance visual acuity (CDVA), maximum keratometry (K1), minimum keratometry (K2), spherical equivalent, and astigmatism...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28944512/comprehensive-evaluation-of-decellularized-porcine-corneal-after-clinical-transplantation
#18
Yan Shi, Timur Bikkuzin, Zhen Song, Xin Jin, Hao Jin, Xinlei Li, Hong Zhang
Corneal disease is the second most common blinding disease in the world. The shortage of cornea donors has become the greatest challenge in curing corneal disease. Decellularized porcine corneas have the potential to be clinically applied as a substitute for human cornea in lamellar keratoplasty. Porcine corneas will help relieve the cornea donor shortage. To comprehensively evaluate the characteristics of the grafts and the effect of the decellularized porcine cornea on the host cornea after clinical transplantation, we assessed the microstructure of the transplanted decellularized porcine corneal tissues...
September 24, 2017: Xenotransplantation
https://www.readbyqxmd.com/read/28943388/corneal-higher-order-aberrations-and-visual-improvement-following-corneal-transplantation-in-treating-herpes-simplex-keratitis
#19
Eisuke Shimizu, Takefumi Yamaguchi, Daisuke Tomida, Yukari Yagi-Yaguchi, Yoshiyuki Satake, Kazuo Tsubota, Jun Shimazaki
PURPOSE: To examine corneal higher-order aberrations (HOAs) and visual improvement following corneal transplantation in treating corneal scar caused by herpes simplex keratitis (HSK). DESIGN: Retrospective consecutive case series. METHODS: This study included a total of 52 eyes: 18 normal subjects, and 34 eyes of consecutive patients with corneal scar due to HSK who underwent penetrating keratoplasty (PKP, 17 eyes) or deep anterior lamellar keratoplasty (DALK, 17 eyes)...
September 21, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28940116/a-comparative-study-deep-anterior-lamellar-keratoplasty-for-corneal-dystrophies-using-two-different-donor-stromal-tissues
#20
Yusuf Koçluk, Emine Alyamaç Sukgen
PURPOSE: This study aimed to present a comparison of early postoperative results of deep anterior lamellar keratoplasty (DALK) surgery performed using the two different corneal graft sources. MATERIALS AND METHODS: This retrospective clinical study included the surgery performed on 26 eyes of 26 patients who underwent DALK for the stromal dystrophies. At the time of surgery, donor stromal tissue for DALK was sourced using the two different preparatory techniques...
September 22, 2017: International Ophthalmology
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