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Local anesthesia

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https://www.readbyqxmd.com/read/29912819/a-randomized-controlled-trial-of-balloon-dilation-as-a-treatment-for-persistent-eustachian-tube-dysfunction-with-1-year-follow-up
#1
Ted A Meyer, Ellen M O'Malley, Rodney J Schlosser, Zachary M Soler, Jason Cai, Mark J Hoy, Patrick W Slater, Jeffrey L Cutler, Roger J Simpson, Michael J Clark, Habib G Rizk, Theodore R McRackan, Christopher F D'Esposito, Shaun A Nguyen
OBJECTIVE: Compare Eustachian tube balloon dilation versus continued medical therapy (control) for treating persistent Eustachian tube dysfunction (ETD). STUDY DESIGN: Prospective, multicenter, randomized controlled trial. SETTING: Tertiary care academic center and private practice. PATIENTS: Diagnosed with medically refractory persistent ETD. INTERVENTIONS: 1:1 Randomization to balloon dilation or control...
June 15, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29908904/application-of-composite-dissolving-microneedles-with-high-drug-loading-ratio-for-rapid-local-anesthesia
#2
Haohui Zhan, Fengsen Ma, Yingcong Huang, Jie Zhang, Xiayun Jiang, Yongchang Qian
We report a type of dissolving microneedles (DMNs) which was made of composite matrix materials of hydroxypropyl methyl cellulose (HPMC) and poly(methylvinylether‑co‑maleic anhydride) (PMVE/MA copolymer, Gantrez S-97), and was successfully loaded with lidocaine hydrochloride. The weight of lidocaine hydrochloride loaded in the microneedles tip was 70% of the weight of the whole tip. The content was 3.43 ± 0.12 mg in weight, which was determined by high performance liquid chromatography (HPLC). The results for mechanical test showed that these microneedles were able to penetrate into the skin of the experimental animals, that was proved using organic staining, texture analyzer and histological examination...
June 14, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29908296/sonographically-guided-plantaris-tendon-release-a-cadaveric-validation-study
#3
Jay Smith, Håkan Alfredson, Lorenzo Masci, Jacob L Sellon, Charonn D Woods
BACKGROUND: The plantaris tendon (PT) has been implicated in the pathogenesis of symptoms in a subset of patients with Achilles region pain syndromes and has been traditionally managed via open surgical resection. Although the PT can be visualized on ultrasound, a minimally invasive technique for sonographically guided PT release has not been formally described. OBJECTIVE: To validate a technique to perform sonographically guided PT release in an unembalmed cadaveric model...
June 13, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29907575/current-evidence-for-anesthesia-management-during-endovascular-stroke-therapy-updated-systematic-review-and-meta-analysis
#4
Nitin Goyal, Konark Malhotra, Muhammad F Ishfaq, Georgios Tsivgoulis, Christopher Nickele, Daniel Hoit, Adam S Arthur, Andrei V Alexandrov, Lucas Elijovich
INTRODUCTION: Debate continues about the optimal anesthetic management for patients undergoing endovascular treatment (ET) of acute ischemic stroke due to emergent large vessel occlusion. OBJECTIVE: To compare, using current evidence, the clinical outcomes and procedural characteristics among patients undergoing general anesthesia (GA) and local or monitored anesthesia (non-GA). METHODS: We performed a systematic review and meta-analysis of all available studies that involved the use of stent retrievers for ET (stentriever group)...
June 15, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29905631/ultrasound-guided-selective-versus-conventional-block-of-the-medial-brachial-cutaneous-and-the-intercostobrachial-nerves-a-randomized-clinical-trial
#5
Philippe Magazzeni, Denis Jochum, Gabriella Iohom, Gérard Mekler, Eliane Albuisson, Hervé Bouaziz
BACKGROUND AND OBJECTIVES: For superficial surgery of anteromedial and posteromedial surfaces of the upper arm, the medial brachial cutaneous nerve (MBCN) and the intercostobrachial nerve (ICBN) must be selectively blocked, in addition to an axillary brachial plexus block. We compared efficacy of ultrasound-guided (USG) versus conventional block of the MBCN and the ICBN. METHODS: Eighty-four patients, undergoing upper limb surgery, were randomized to receive either USG (n = 42) or conventional (n = 42) block of the MBCN and the ICBN with 1% mepivacaine...
June 13, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29905607/reconstruction-of-large-defects-of-the-lower-lip-after-mohs-surgery-the-use-of-combined-karapandzic-and-abbe-flaps
#6
Abel Gonzalez, Dardo Etchichury
INTRODUCTION: Lower lip reconstruction should restore oral competence, speech, and cosmesis. These goals are a challenge when reparing large lower lip defects. Karapandzic flap is a reliable technique with consistent functional and esthetic outcome. In large defects, it might result in disproportion between the upper and lower lips and blunting of the commissures. The Abbe flap is useful as a lip balancing procedure and avoids the rounding of the commissures. PATIENTS AND METHODS: Five cases of lower lip skin cancer treated with Mohs surgery with defects up to 80% were reconstructed with a combination of Karapandzic and Abbe flaps...
June 13, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29902447/randomized-controlled-trial-of-belladonna-and-opiate-suppository-during-intravesical-onabotulinum-toxin-a-injection
#7
Edgar L Leclaire, Jennifer Duong, Rachel M Wykes, Kevin E Miller, Tessa L Winterton, Milan Bimali
BACKGROUND: Intravesical injection with onabotulinum toxin A (BTX-A) injection can be performed in-office under local anesthesia. Rectally administered pain medication presents a potentially feasible and previously uninvestigated adjunct to office-based anesthesia protocols. OBJECTIVES: The primary aim of this study was to determine whether adding a belladonna and opiate (BO) suppository to standard lidocaine instillation resulted in reduction of bladder injection pain during BTX-A injection procedure...
June 11, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29902215/clinical-analgesic-efficacy-of-dexamethasone-as-a-local-anesthetic-adjuvant-for-transversus-abdominis-plane-tap-block-a-meta-analysis
#8
Qi Chen, Ran An, Ju Zhou, Bin Yang
BACKGROUND: Perineural dexamethasone has been shown to prolong the duration of local anesthetic (LA) effect in regional anesthesia; however, the use of perineural dexamethasone as an adjuvant to to the transversus abdominis plane (TAP) block remains controversial. This meta-analysis sought to assess the efficacy of dexamethasone in prolonging the TAP block and enhancing recovery after abdominal surgery. METHODS: We identified and analyzed 9 RCTs published on or before September 30, 2017, regardless of the original language, after searching the following 6 bibliographic databases: PubMed, EMBASE, Medline, Springer, Ovid, and the Cochrane Library...
2018: PloS One
https://www.readbyqxmd.com/read/29901598/the-effect-of-interscalene-block-on-ipsilateral-shoulder-pain-and-pulmonary-function-in-patients-undergoing-lung-lobectomy-a-randomized-controlled-trial
#9
Jae Hee Woo, Youn Jin Kim, Kwan Chang Kim, Chi Hyo Kim, Jeeyoung Jun
BACKGROUND: Postoperative ipsilateral shoulder pain occurs in 37% to 68% of patients undergoing a thoracotomy. We examined whether interscalene brachial plexus block using a lower concentration of local anesthetic would reduce the incidence of post-thoracotomy ipsilateral shoulder pain with assessment of pulmonary function in patients who underwent a lung lobectomy. METHODS: Forty-four patients who underwent a lung lobectomy were randomly assigned to either the control or the interscalene block group...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29899641/effect-of-local-anesthesia-containing-vasoconstrictor-on-sealing-ability-of-dentin-with-two-adhesive-systems-dye-leakage-and-scanning-electron-microscopy-study
#10
Rakesh Singla, Sanjay Tewari, Jigyasa Duhan, Sudhir Kumar, Gurdeep Singh Gill, Namita Jain
Objectives: To evaluate the effect of 2% lignocaine containing 1:80,000 adrenaline on the microleakage and ultrastructure of resin tooth interface using an acetone based total etch adhesive (Prime and Bond NT) and an ethanol water based self etch adhesive system (Xeno III). Materials and method: Class V cavities were prepared on buccal surfaces of 72 maxillary first premolars scheduled for orthodontic extraction. In 36 premolars procedure was performed under local anaesthesia (LA) and in other 36 teeth without LA...
May 2018: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/29898873/effectiveness-and-safety-of-local-anesthetic-semi-flexible-pleuroscopy-experience-from-a-peripheral-hospital
#11
L V Rodrigues, G Samouco, R Gomes, C Santos, L Ferreira
If the seemingly less invasive semi-flexible pleuroscopes are combined with strategies of conscious sedation and local anesthesia the pleuroscopy has the potential to reach an increasing number of hospital settings. Local experiences can provide valuable information pertaining to the reproducibility of this technique in different scenarios. We performed a retrospective analysis of the clinical records of all patients that had undergone local anesthetic semi-flexible pleuroscopy in our unit between February 2015 and July 2017...
June 10, 2018: Pulmonology
https://www.readbyqxmd.com/read/29896560/single-dose-lidocaine-spinal-anesthesia-in-hip-and-knee-arthroplasty
#12
Nicholas B Frisch, Brian Darrith, Dane C Hansen, Adrienne Wells, Sheila Sanders, Richard A Berger
Background: With the increasing interest in fast recovery and outpatient joint arthroplasty, short-acting local anesthetic agents and minimal narcotic use are preferred. Lidocaine is a fast-onset, short-duration local anesthetic that has been used for many years in spinal anesthesia. However, lidocaine spinal anesthesia has been reported to have a risk of transient neurologic symptoms (TNSs). The purpose of this study is to determine the safety and efficacy of single-dose lidocaine spinal anesthesia in the setting of outpatient joint arthroplasty...
June 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29895029/bronchoscopic-thermal-vapor-ablation-best-practice-recommendations-from-an-expert-panel-on-endoscopic-lung-volume-reduction
#13
Daniela Gompelmann, Pallav L Shah, Arschang Valipour, Felix J F Herth
Bronchoscopic thermal vapor ablation (BTVA) represents one of the endoscopic lung volume reduction (ELVR) techniques that aims at hyperinflation reduction in patients with advanced emphysema to improve respiratory mechanics. By targeted segmental vapor ablation, an inflammatory response leads to tissue and volume reduction of the most diseased emphysematous segments. So far, BTVA has been demonstrated in several single-arm trials and 1 multinational randomized controlled trial to improve lung function, exercise capacity, and quality of life in patients with upper lobe-predominant emphysema irrespective of the collateral ventilation...
June 12, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29892577/488-hand-surgeries-with-local-anesthesia-with-epinephrine-without-a-tourniquet-without-sedation-and-without-an-anesthesiologist
#14
Trajano Sardenberg, Samuel Ribak, Ricardo Colenci, Rafael Barcellos de Campos, Denis Varanda, Andrea Christina Cortopassi
Objectives: Evaluate the incidence of digital infarction and tissue necrosis using local anesthesia with 1% lidocaine and 1:100,000 epinephrine in wrist, hand, and fingers surgeries, without a tourniquet, without sedation, and without an anesthesiologist. Methods: Patients with wrist, hand, and fingers disorders prospectively underwent surgery under local anesthesia with 1% lidocaine and 1:100,000 epinephrine. The primary outcomes evaluated were the presence of digital infarction and tissue loss due to necrosis...
May 2018: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29892533/comparative-evaluation-of-efficacy-of-emla-and-needleless-jet-anesthesia-in-non-surgical-periodontal-therapy
#15
Rajan Gupta, Satwinder Kaur, Parveen Dahiya, Mukesh Kumar
The treatment of periodontitis primarily consists of mechanical debridement carried out by means of thorough scaling and root planing that might sometimes be a painful procedure which requires the administration of some form of local anesthesia. The present study comparatively evaluates the anesthetic effect of three such forms, viz; eutectic mixture of 25 mg/g lignocaine plus 25 mg/g prilocaine (EMLA) and needleless jet anesthesia during SRP. 30 patients with probing depth of 5 mm or more and visual analog scale (VAS) score of ≥30 mm on probing were selected and asked to assess the pain by VAS and verbal rating scale (VRS) during SRP after application of the two agents...
May 2018: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/29890234/principles-and-practice-of-hdr-penile-brachytherapy-planning-and-delivery-techniques
#16
Shireen Parsai, Sheen Cherian, Ryan K Berglund, Byron Lee, Matthew Kolar, Nancy Nagle-Hernan, Allan Wilkinson, Jay Ciezki
OBJECTIVES: To allow for organ preservation, high dose rate brachytherapy may be used in the treatment of localized penile cancer. Penile cancer is a rare malignancy, accounting for less than one percent of cancers in men in the United States. The standard treatment for localized disease is partial amputation of the penis. However, patients with T1b or T2 disease, less than 4 cm in maximum dimension and confined to the glans penis may be treated with brachytherapy as an organ-sparing approach...
June 8, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29887383/-complications-with-surgical-treatment-of-basal-cell-carcinomas-in-individuals-over-75-years-of-age-a-retrospective-study-of-prognostic-factors-in-158-cases
#17
A Chossat, O Marco, M Chaouat, M Mimoun, D Boccara
INTRODUCTION: Basal cell carcinoma (BCC) is a pathology that evolves locally and it is common in elderly subjects whose frailty could restrict the indications for the reference treatment, which is based on surgery. The aim of this study was to investigate the morbidity and the mortality associated with surgical treatment of BCC in patients over 75 years of age, so as to identify possible prognostic factors for postoperative complications. MATERIALS AND METHODS: This was a retrospective study carried out with patients over 75 years of age who were treated surgically for one or several BCC between 2010 and 2015 in the reconstructive and cosmetic plastic surgery unit of the Saint-Louis Hospital in Paris (France)...
June 7, 2018: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/29886206/short-term-efficacy-of-inguinal-reoperation-for-recurrent-saphenofemoral-incompetence-using-the-stump-suture-technique
#18
Stefania Aglaia Gerontopoulou, Wilhelm Kath, Knuth Rass
OBJECTIVES: Neovascularization from the saphenofemoral junction (SFJ) is regarded to be an important cause of clinical recurrence. The ideal treatment of SFJ recurrence is still matter of debate. Barrier strategies have been implemented to improve surgical outcome by reducing neovascularization. This study analyses the value of inguinal reoperation for recurrent SFJ incompetence using a combined approach of stump suture technique, removal of neovasculates, cauterization of free endothelium and additional tumescent local anesthesia...
June 7, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29884529/-effects-of-local-anesthetics-on-wound-healing
#19
Sevgi Kesici, Ugur Kesici, Hulya Ulusoy, Pelin Erturkuner, Aygen Turkmen, Oktay Arda
INTRODUCTION: Local anesthetic infiltration is used widely for post-operative analgesia in many situations. However the effects of local anesthetics on wound healing are not demonstrated clearly. This study planned to evaluate the effects of lidocaine, prilocaine, bupivacaine and levobupivacaine on wound healing, primarily on wound tensile strength and on collagen ultrastructure. METHODS: This study was conducted on male Sprague Dawley rats. On days 0, 8th, 15th, and 21st, all animals were weighed and received a preincisional subcutaneous infiltration of 3mL of a solution according the group...
June 5, 2018: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/29882201/palatal-schwannoma-in-a-young-female-patient-report-of-a-case-and-review-of-the-literature
#20
P Tamiolakis, D Kalyvas, I Arvanitidou, A Vlachaki, K I Tosios, A Sklavounou-Andrikopoulou
BACKGROUND: A few cases of oral schwannomas in paediatric patients have appeared in the literature so far; however, there are no studies focusing solely on paediatric oral schwannomas. The aim of this study is to report a case of palatal schwannoma in a young female patient and review the pertinent literature on oral schwannomas in paediatric patients. CASE REPORT: A 12-year-old girl presented with a growing swelling of 2 weeks duration on the hard palate. With a provisional diagnosis of a salivary gland neoplasm an incisional biopsy was performed under local anesthesia and the histologic examination disclosed an Antony A type schwannoma...
June 7, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
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