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Caveat emptor

John Riefler
No abstract text is available yet for this article.
September 2017: American Journal of the Medical Sciences
Robert W Bailey, Kevin E Vowles
Screening tests represent a critical tool in chronic pain treatment for predicting aberrant opioid use, which has emerged as a significant public health issue. Nevertheless, there remains a significant potential for the misapplication of screeners in this context. The potential difficulties in evaluating the diagnostic efficiency of screeners have been well established, particularly with regard to the impact that the prevalence of a disorder has on predictive value. The wide range in the reported prevalence of aberrant opioid use behaviors makes it difficult to interpret data obtained from popular screeners for assessing the potential for the aberrant use of opioids...
June 29, 2017: Journal of Pain: Official Journal of the American Pain Society
Gary M Heir
No abstract text is available yet for this article.
April 2017: Journal of the American Dental Association
Josephine C Adams
In a recent publication in Bioscience Reports "Contaminants in commercial preparations of 'purified' small leucine-rich proteoglycans may distort mechanistic studies", Brown et al. identified by mass spectrometry and immunoblotting that certain commercial preparations of the small leucine-rich proteoglycans (SLRPs) decorin and biglycan, in fact, contained a mix of several proteoglycans that also included fibromodulin and aggrecan. The preparations were thus not suitable to study specific activities of decorin or biglycan...
June 30, 2017: Bioscience Reports
J Sanz, R P Gale
No abstract text is available yet for this article.
January 9, 2017: Bone Marrow Transplantation
Sonia R Talwar, Amarita S Randhawa, Erica H Dankiewicz, Nancy T Crudele, J David Haddox
BACKGROUND: Healthcare professionals and consumers refer to online drug-information compendia (eg, Epocrates and WebMD) to learn about prescription medications, including opioid analgesics. With the significant risks associated with opioids, including abuse, misuse, and addiction, any of which can result in life-threatening overdose, it is important for those seeking information from online compendia to have access to current, accurate, and complete drug information to help support clinical treatment decisions...
July 2016: Journal of Opioid Management
(no author information available yet)
Caveat emptor ('Let the buyer beware').
July 8, 2016: British Dental Journal
Fabio Angeli, Gianpaolo Reboldi, Paolo Verdecchia
No abstract text is available yet for this article.
August 2016: Journal of Hypertension
David M Harlan
No abstract text is available yet for this article.
July 2016: Diabetes Care
Barry Schlansky, Carmel Shachar
No abstract text is available yet for this article.
August 2016: Liver Transplantation
Daniel F Hayes
Physicians have provided personalized care with as much precision as possible for several centuries. However, increasingly sophisticated understanding of the human genome and of cancer biology has permitted identification of genetic and phenotypic distinctions that might permit development of new tumor biomarker tests for risk categorization, screening, differential diagnosis, prognosis, prediction, and monitoring. Both commercial and academic laboratories are offering tests for single analytes, panels of tests of single analytes, multiparameter assays coalesced into a signature, and total genomic, transcriptomic, or proteomic analyses...
2016: American Society of Clinical Oncology Educational Book
Thomas R Vetter, Gerald McGwin, Jean-Francois Pittet
No abstract text is available yet for this article.
July 2016: Anesthesia and Analgesia
Thomas F Imperiale, Douglas K Rex
No abstract text is available yet for this article.
September 2016: Gastrointestinal Endoscopy
Christopher P Filson
No abstract text is available yet for this article.
June 2016: Nature Reviews. Urology
Mark I Evans, Ronald J Wapner, Richard L Berkowitz
The past few years have seen extraordinary advances in prenatal genetic practice led by 2 major technological advances; next-generation sequencing of cell-free DNA in the maternal plasma to noninvasively identify fetal chromosome abnormalities, and microarray analysis of chorionic villus sampling and amniotic fluid samples, resulting in increased cytogenetic resolution. Noninvasive prenatal screening of cell-free DNA has demonstrated sensitivity and specificity for trisomy 21 superior to all previous screening approaches with slightly lower performance for other common aneuploidies...
September 2016: American Journal of Obstetrics and Gynecology
Martijn Arns, Sandra K Loo, M Barry Sterman, Hartmut Heinrich, Jonna Kuntsi, Philip Asherson, Tobias Banaschewski, Daniel Brandeis
Recently several new tests have received US Federal Drug Administration (FDA) marketing approval as aids in the diagnostic process for attention deficit hyperactivity disorder (ADHD), including the Neuropsychiatric electroencephalogram (EEG)-Based ADHD Assessment Aid (NEBA) Health test. The NEBA test relies upon an EEG-based measure, called the theta to beta ratio (TBR). Although this measure has yielded large differences between ADHD and non-ADHD groups in studies prior to 2009, recent studies and a meta-analysis could not replicate these findings...
May 2016: Journal of Child Psychology and Psychiatry, and Allied Disciplines
(no author information available yet)
No abstract text is available yet for this article.
January 2016: Physiologist
Bruce W Sherman, Thomas Parry
No abstract text is available yet for this article.
June 2016: Population Health Management
Sandra P Thomas
No abstract text is available yet for this article.
2015: Issues in Mental Health Nursing
Michelle Bowman, Michael Racke, John Kissel, Jaime Imitola
"Stem cell tourism" is a rising Internet-based industry that aims to offer unproven procedures to patients with incurable diseases. This unregulated activity is reaching the neurologist's office as well as across the world, as patients request information or clearance for such procedures. Herein, we posit the need for medical societies and licensing boards to bring this issue to the forefront of neurology because it has the potential to affect patient care with risk of morbidity and mortality, as well as to undermine public confidence in legitimate stem cell research for incurable neurological diseases such as multiple sclerosis and amyotrophic lateral sclerosis...
November 2015: JAMA Neurology
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