keyword
MENU ▼
Read by QxMD icon Read
search

Osteoporosis herbal

keyword
https://www.readbyqxmd.com/read/28926512/orthosiphon-stamineus-misai-kucing-ameliorated-postmenopausal-osteoporosis-in-rat-model
#1
Rubiatul Adawiyah Bokhari, Seng Fong Lau, Suhaila Mohamed
OBJECTIVE: Orthosiphon stamineus (OS) or Misai Kucing (Java tea) is a popular herbal supplement from Southeast Asia for various metabolic, age-related diseases. This study investigated the potential use of OS leaf extracts to ameliorate osteoporosis in ovariectomized rats. METHODS: Fifty-six female Sprague-Dawley rats were randomly allocated into eight groups (n = 7): SHAM (healthy sham control); OVX (ovarietomized) nontreated rats (negative control); OVX + Remifemin (100 mg/kg body weight), and 2% green tea extract (positive controls); OVX + OS 50% ethanolic and aqueous extracts, both at either 150 or 300 mg/kg...
September 18, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28893468/chinese-herbal-medicine-for-osteoporosis-a-meta-analysis-of-randomized-controlled-trials
#2
REVIEW
Yong-Xiang Jin, Peng Wu, Yi-Fan Mao, Bo Wang, Jia-Feng Zhang, Wen-Liang Chen, Zhong Liu, Xiao-Lin Shi
Osteoporosis is a major public health problem in the elderly population. Several studies have suggested that Chinese herbal medicine has antiosteoporotic activities that might be beneficial for osteoporosis. This study aimed to assess the effectiveness of Chinese herbal medicine in osteoporosis patients. We comprehensively searched for randomized controlled trials (until December 2016) that compared Chinese herbal medicine with Western medicine in adults with osteoporosis and reported bone mineral densities (BMDs)...
September 8, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28826891/traditional-uses-phytochemistry-pharmacology-and-toxicology-of-the-genus-cimicifuga-a-review
#3
REVIEW
Yaqing Guo, Tong Yin, Xiaoming Wang, Fan Zhang, Guixiang Pan, Hong Lv, Xianrui Wang, John Owoicho Orgah, Yan Zhu, Honghua Wu
ETHNOPHARMACOLOGICAL RELEVANCE: Plants of the genus Cimicifuga have long been used as an ethnomedicine in China, Europe, and North America for its high medicinal value and health benefits. Their dried rhizomes are widely used for treating wind-heat headache, toothache, aphtha, sore throat, measles, spot poison, archoptosis, and uterine prolapse. In addition, it is used as a dietary supplement for preventing women menopausal symptoms and osteoporosis. AIM OF THE REVIEW: This paper aims to provide up-to-date information on the genus Cimicifuga, including botanical characterization, medicinal resources, traditional medicinal uses, phytochemistry, quality control, pharmacological research as well as the toxicology...
August 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28821095/an-o-acetyl-glucomannan-from-the-rhizomes-of-curculigo-orchioides-structural-characterization-and-anti-osteoporosis-activity-in-vitro
#4
Xueqian Wang, Mengliu Zhang, Dawei Zhang, Shumei Wang, Chunyan Yan
Osteoporosis is characterized by a reduction in bone mass and bone mineral density, which weakens the bone. Due to the side effects associated with drugs that are currently used to treat this disease, an increasing number of studies have focused on the research of effective ingredients derived from natural products. In particular, polysaccharides extracted from Chinese herbal medicines have received increasing attention. In this study, we isolated a homogeneous polysaccharide (COP90-1) from the dried rhizomes of Curculigo orchioides, a famous traditional Chinese medicine that is widely used in China, and determined its structure using the combined methods of chemical and spectral analyses...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28804568/preventive-effects-of-kudzu-root-on-bone-loss-and-cartilage-degradation-in-ovariectomized-rat
#5
Yunyun Luo, Shuang Zheng, Yujia Ding, Yueqin Dai, Yi Zhou, Ruifeng Xiang, Anne C Bay-Jensen, Morten A Karsdal, Per Qvist, Qinlong Zheng
The clinical utility of Traditional Chinese Medicine (TCM) herbs/roots extracts in osteoporosis (OP) and osteoarthritis (OA) has been described in multiple reports, but there have been few studies of TCM for preventing bone loss and cartilage degradation simultaneously. Six-month-old female Sprague-Dawley rats each were subjected to ovariectomized (OVX) or sham surgery and treated orally once daily with herbal extracts or vehicle. Body weight was recorded weekly, and blood samples were collected from fasting animals at different time points...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28743091/performance-comparison-of-two-herbal-and-industrial-medicines-using-nanoparticles-with-a-starch-cellulose-shell-and-alginate-core-for-drug-delivery-in-vitro-studies
#6
Akbar Esmaeili, Sahar Behzadi
In this study, the performance of two kinds of industrial and herbal drugs encapsulated in nanoparticles with a shell of starch and cellulose and an alginate core were examined as a new technique for nanoparticle drug delivery. The test method involved creating a suspension of starch and alginate, which was then dried, mixed with cellulose, and heated to form core-shell nanoparticles. The industrial drug calcitonin and an extract of the herb Amaranthus retroflexcus L. were added separately and in combination to the nanoparticles, and the performance of each configuration was evaluated...
July 18, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28738286/emodin-suppresses-cadmium-induced-osteoporosis-by-inhibiting-osteoclast-formation
#7
Xiao Chen, Shuai Ren, Guoying Zhu, Zhongqiu Wang, Xiaolin Wen
Environmental level of cadmium (Cd) exposure can induce bone loss. Emodin, a naturally compound found in Asian herbal medicines, could influence osteoblast/osteoclast differentiation. However, the effects of emodin on Cd-induced bone damage are not clarified. The aim of this study was to investigate the role of emodin on Cd-induced osteoporosis. Sprague-Dawley male rats were divided into three groups which were given 0mg/L, 50mg Cd/L and 50mg Cd/L plus emodin (50mg/kg body weight). Bone histological investigation, microCT analysis, metabolic biomarker determination and immunohistochemical staining were performed at the 12th week...
July 18, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28714404/current-and-emerging-strategies-in-osteoporosis-management
#8
Stefka Ivanova, Liliya Vasileva
The abnormal loss of bone tissue is defined as osteoporosis. Increased risk of fractures, low bone mineral density (BMD) and loss of the structural and biomechanical properties of the bone tissue characterize this pathological condition. Physiologically bone undergoes a continuous remodeling process involving balance between the activity of osteoblast and osteoclast. Disruption in this balanced condition increases the risk of osteoporosis. Both sexes are affected, but with higher prevalence in women after menopause...
July 14, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28512501/effect-of-traditional-chinese-medicine-product-qiangguyin-on-bone-mineral-density-and-bone-turnover-in-chinese-postmenopausal-osteoporosis
#9
Zhen-Yu Shi, Xin-Gen Zhang, Chun-Wen Li, Kang Liu, Bo-Cheng Liang, Xiao-Lin Shi
Introduction. The aim of this study was to investigate the efficacy of herbal formula QiangGuYin (QGY) in postmenopausal women. Materials and Methods. A total of 240 participants from six clinical centers were randomly to receive alendronate 70 mg/week, QGY granules 20 g/day, and placebo. Primary end points were BMD changes over 6 and 12 months; secondary end points were bone turnover markers changes at 3, 6, 9, and 12 months. Safety was monitored by clinical adverse events reported during the follow-up...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28325144/therapeutic-potential-and-outlook-of-alternative-medicine-for-osteoporosis
#10
Tao Wang, Qian Liu, William Tjhioe, Jinmin Zhao, Aiping Lu, Ge Zhang, Ren Xiang Tan, Mengyu Zhou, Jiake Xu, Hao Tian Feng
Osteoporosis, a bone disease resulting in the loss of bone density and microstructure quality, is often associated with fragility fractures, and the latter imposes a great burden on the patient and society. Although there are several different treatments available for osteoporosis such as hormone replacement therapy, bisphosphonates, Denosumab, and parathyroid hormone, some concerns have been raised regarding the inherent side effects of their long term use. It would be of great relevance to search for alternative natural compounds, which could complementarily overcome the limitations of the currently available therapy...
2017: Current Drug Targets
https://www.readbyqxmd.com/read/28119100/antiosteoporotic-effect-of-hemidesmus-indicus-linn-on-ovariectomised-rats
#11
Sharad Desai, Parth Babaria, Madhavi Nakarani, Kunal Shah, Archana Paranjape
PHARMACOLOGICAL RELEVANCE: Root of Hemidesmus indicus (L). R. Br., an herbal drug of India is traditionally used to prevent or treat female hormonal disturbance related disorders and assuaging symptoms of menopausal conditions. AIM OF THE STUDY: Lack of scientific data for potential use in bone loss, the present study was undertaken to investigate the effects of ethanol extract of Hemidesmus indicus root for osteoporosis in ovariectomised rats. MATERIALS AND METHODS: Thirty wistar female rats were randomly divided into five groups...
March 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28115834/effects-of-chinese-herbal-formula-erxian-decoction-for-treating-osteoporosis-a-systematic-review
#12
Jin-Yu Li, Yu-Song Jia, Li-Min Chai, Xiao-Hong Mu, Sheng Ma, Lin Xu, Xu Wei
PURPOSE: The aim is to systematically assess the effectiveness and safety of Chinese herbal formula Erxian decoction (EXD) for treating osteoporosis. MATERIALS AND METHODS: Six databases were searched from inception through September 17, 2016, without language restriction. All randomized controlled trials of EXD for osteoporosis were included. One or more outcome measures including fracture, change in bone mineral density (BMD), pain symptom improvement, bone biochemical markers, quality of life, adverse event or adverse drug reaction were evaluated...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28074748/possible-parkinson-s-disease-induced-by-chronic-manganese-supplement-ingestion
#13
Michael J Schuh
OBJECTIVE: The objective is to report a case of possible neurotoxicity resulting from an incorrect dietary supplement for osteoporosis taken at a toxic dose. SUMMARY: The case study examined here is a 37-year-old African-American female who consumed excessive manganese over a period of years, resulting in Parkinson's disease (PD). This patient was referred to the pharmacist pharmacotherapy service by a neurology physician. PD has been shown in the medical literature to be caused by chronic exposure to high levels of manganese...
December 1, 2016: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28040510/du-huo-ji-sheng-tang-and-its-active-component-ligusticum-chuanxiong-promote-osteogenic-differentiation-and-decrease-the-aging-process-of-human-mesenchymal-stem-cells
#14
Jir-You Wang, Wei-Ming Chen, Che-Sheng Wen, Shih-Chieh Hung, Pei-Wen Chen, Jen-Hwey Chiu
ETHNOPHARMACOLOGICAL RELEVANCE: Postmenopausal osteoporosis is the most common bone disease worldwide. Information concerning the effects of herbal medicines on mesenchymal cell osteogenesis and senescence remains lacking. AIM OF THIS STUDY: This study was designed to investigate the effects of Du-Huo-Ji-Sheng-Tang (DHJST), a Chinese herbal medicine and its active component Ligusticum chuanxiong on osteogenic differentiation and the aging process of human mesenchymal cells (hMSCs)...
February 23, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27959402/effects-of-herbal-epimedium-on-the-improvement-of-bone-metabolic-disorder-through-the-induction-of-osteogenic-differentiation-from-bone-marrow-derived-mesenchymal-stem-cells
#15
Do Rim Kim, Ji Eun Lee, Kyung Jun Shim, Jin Hyoung Cho, Ho Chul Lee, Seong Kyu Park, Mun Seog Chang
Herbal Epimedium (HE) has been commonly used as a tonic, antirheumatic agent and in the treatment of bone‑associated diseases including osteoporosis. Treatment for osteoporosis is important to increase bone mass density and maintain to balance of bone remodeling. The present study was performed to investigate the effects of HE on mouse bone marrow mesenchymal stem cell (mBMMSC) proliferation and osteogenic differentiation, using MTT assays, proliferating cell nuclear antigen (PCNA) detection and apoptosis and differentiation assays...
January 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27848901/herb-medicines-against-osteoporosis-active-compounds-relevant-biological-mechanisms
#16
REVIEW
Lei Wu, Zhuoyan Ling, Xueqin Feng, Caiping Mao, Zhice Xu
Osteoporosis is one of common bone disorders, affecting millions of people worldwide. Treatments of osteoporosis consist of pharmacotherapy and non-pharmacological interventions, such as mineral supplementation, lifestyle changes, and exercise programs. Due to the minimum side effects and favorable cost-effective therapeutic effects, herbal medicine has been widely applied in clinical practices for more than 2,000 years in China. Of the many traditional formulas reported for treating bone diseases, 4 single herbs namely (1) Herba Epimedii, (2) Rhizoma Drynariae, (3) Fructus Psoraleae, and (4) Cortex Eucommiae, are considered as the featured "Kidney-Yang" tonics, and frequently and effectively applied for preventing and treating osteoporosis...
2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/27516660/complementary-and-alternative-medicine-for-osteoporosis
#17
Zahra Alsadat Hejazi, Forough Namjooyan, Marjan Khanifar
BACKGROUND: A systemic skeletal disease is characterized by low bone mass and micro-architectural deterioration with a consequent increase in bone fragility and susceptibility to fracture. Asia has the highest increment in the elderly population; therefore, osteoporotic fracture should be a noticeable health issue. The incidence rate of hip fractures in Asia could rise to 45% by the year 2050. Complementary and alternative medicine (CAM) is a group of various medical and health care systems, practices, and products that are not presently considered as part of formal medicine...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27515026/potential-role-of-herbal-remedies-in-stem-cell-therapy-proliferation-and-differentiation-of-human-mesenchymal-stromal-cells
#18
REVIEW
Vindya Lankika Udalamaththa, Chanika Dilumi Jayasinghe, Preethi Vidya Udagama
Stem cell therapy has revolutionized modern clinical therapy with the potential of stem cells to differentiate into many different cell types which may help to replace different cell lines of an organism. Innumerous trials are carried out to merge new scientific knowledge and techniques with traditional herbal extracts that may result in less toxic, affordable, and highly available natural alternative therapeutics. Currently, mesenchyamal stromal cell (MSC) lines are treated with individual and mixtures of crude herbal extracts, as well as with purified compounds from herbal extracts, to investigate the mechanisms and effects of these on stem cell growth and differentiation...
August 11, 2016: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27456335/dzqe-activates-ampk-pathway-and-regulates-lipid-metabolism-in-a-rat-model-of-perimenopausal-hyperlipidemia
#19
Xiaoxue Xing, Lina Su, Patrick Fordjour Asare, Lingyan Wang, Lan Li, Erwei Liu, Bing Yu, Yan Zhu, Xiumei Gao, Guanwei Fan
BACKGROUND: Menopause is an important event in a female's life. During perimenopause, together with osteoporosis and dyslipidemia, ovary function gradually declines. Dyslipidemia is a risk factor for cardiovascular disorder, cerebrovascular disease and breast cancer in postmenopausal women. All of these contribute to impairment of liver function, particularly fatty liver disease. Since liver dysfunction is associated with ovary dysfunction and hyperlipidemia.Thus, this study aims to define a therapeutic approach to improve ovary function and attenuate lipid accumulation in order to prevent perimenopause-induced ovary dysfunction and hyperlipidemia...
July 25, 2016: Experimental Physiology
https://www.readbyqxmd.com/read/27455321/selection-of-the-optimal-herbal-compositions-of-red-clover-and-pomegranate-according-to-their-protective-effect-against-climacteric-symptoms-in-ovariectomized-mice
#20
COMPARATIVE STUDY
Su Jin Kang, Beom Rak Choi, Seung Hee Kim, Hae Yeon Yi, Hye Rim Park, Chang Hyun Song, Sae Kwang Ku, Young Joon Lee
This study aimed to ascertain the optimal range of red clover dry extracts (RC) and dried pomegranate concentrate powder (PCP) to induce anti-climacteric effects. Thus, the dose ranges showing protective effect of mixed formulae consisting of RC and PCP were examined in ovariectomized mice. At 28 days after bilateral ovariectomy (OVX), mixed herbal compositions (RC:PCP = 1:1, 1:2, 1:4, 1:8, 2:1, 4:1, and 8:1) were administered orally, at 120 mg/kg once daily for 84 days. We evaluated that RC and PCP mixture attenuate OVX-caused obesity, hyperlipidemia, hepatic steatosis, and osteoporosis...
July 23, 2016: Nutrients
keyword
keyword
68434
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"