Annie Wai Yeeng Chai, Shi Mun Yee, Hui Mei Lee, Norazlin Abdul Aziz, Pei San Yee, Marini Marzuki, Ka Wo Wong, Alan K S Chiang, Larry Ka-Yue Chow, Wei Dai, Teng Fei Liu, Lu Ping Tan, Alan Soo Beng Khoo, Kwok Wai Lo, Paul Vh Lim, Pathmanathan Rajadurai, Howard Lightfoot, Syd Barthorpe, Mathew J Garnett, Sok Ching Cheong
Nasopharyngeal carcinoma (NPC), a cancer that is etiologically associated with the Epstein-Barr virus (EBV), is endemic in Southern China and Southeast Asia. The scarcity of representative NPC cell lines owing to the frequent loss of EBV episomes following prolonged propagation and compromised authenticity of previous models underscores the critical need for new EBV-positive NPC models. Herein, we describe the establishment of a new EBV-positive NPC cell line, designated NPC268 from a primary non-keratinizing, differentiated NPC tissue...
February 15, 2024: Cancer Res Commun