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https://www.readbyqxmd.com/read/28819351/a-systematic-analysis-of-term-reuse-and-term-overlap-across-biomedical-ontologies
#1
Maulik R Kamdar, Tania Tudorache, Mark A Musen
Reusing ontologies and their terms is a principle and best practice that most ontology development methodologies strongly encourage. Reuse comes with the promise to support the semantic interoperability and to reduce engineering costs. In this paper, we present a descriptive study of the current extent of term reuse and overlap among biomedical ontologies. We use the corpus of biomedical ontologies stored in the BioPortal repository, and analyze different types of reuse and overlap constructs. While we find an approximate term overlap between 25-31%, the term reuse is only <9%, with most ontologies reusing fewer than 5% of their terms from a small set of popular ontologies...
2017: Semantic Web
https://www.readbyqxmd.com/read/28818965/parent-delivered-cbt-may-reduce-intervention-cost-but-questions-arise-about-effectiveness
#2
Gabriela M Hungerford, Lauren C Santucci, John R Weisz
No abstract text is available yet for this article.
August 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28814658/sperm-competition-games-when-males-invest-in-paternal-care
#3
Gustavo S Requena, Suzanne H Alonzo
Sperm competition games investigate how males partition limited resources between pre- and post-copulatory competition. Although extensive research has explored how various aspects of mating systems affect this allocation, male allocation between mating, fertilization and parental effort has not previously been considered. Yet, paternal care can be energetically expensive and males are generally predicted to adjust their parental effort in response to expected paternity. Here, we incorporate parental effort into sperm competition games, particularly exploring how the relationship between paternal care and offspring survival affects sperm competition and the relationship between paternity and paternal care...
August 16, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28813631/rapid-and-targeted-introgression-of-fgr-gene-through-marker-assisted-backcrossing-in-rice-oryza-sativa-l
#4
Acga Cheng, Ismanizan Ismail, Mohamad Osman, Habibuddin Hashim, Nur Samahah Mohd Zainual
While it is crucial for developing countries like Malaysia to achieve self-sufficiency in rice (Oryza sativa L.), it is equally critical to be able to produce high-quality rice, specifically fragrant rice, which demands are often met through importation. The present study was aimed at developing high-yielding fragrant rice, in a timely and cost-effective manner. A marker-assisted backcross (MABC) approach was optimised to introgress the fragrance gene (fgr) into two high-yielding Malaysian varieties; MR84 and MR219, within two years utilising less than fifty molecular markers...
August 16, 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28813256/parenting-and-hiv
#5
REVIEW
Tamsen Rochat, Elena Netsi, Stephanie Redinger, Alan Stein
With the widespread use of antiretroviral therapy and successful prevention of mother-to-child transmission the development of HIV-negative children with HIV-positive parents has become an important focus. There is considerable evidence that children's developmental risk is heightened because a parental HIV-diagnosis is associated with a range of potential problems such as depression, stigma and financial difficulties. Up to a third of children in sub-Saharan Africa (SSA) are cared for by an HIV-positive parent or caregiver...
June 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28811270/developing-and-evaluating-jiapp-acceptability-and-usability-of-a-smartphone-app-system-to-improve-self-management-in-young-people-with-juvenile-idiopathic-arthritis
#6
Ran A Cai, Dominik Beste, Hema Chaplin, Socrates Varakliotis, Linda Suffield, Francesca Josephs, Debajit Sen, Lucy R Wedderburn, Yiannakis Ioannou, Stephen Hailes, Despina Eleftheriou
BACKGROUND: Flare-ups in juvenile idiopathic arthritis (JIA) are characterized by joint pain and swelling and often accompanied with fatigue, negative emotions, and reduced participation in activities. To minimize the impact of JIA on the physical and psychosocial development and well-being of young people (YP), it is essential to regularly monitor disease activity and side effects, as well as to support self-management such as adherence to treatment plans and engagement in general health-promoting behaviors...
August 15, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28797645/advance-directives-in-hospice-healthcare-providers-a-clinical-challenge
#7
George R Luck, Terry Eggenberger, David Newman, Jacqueline Cortizo, Derek C Blankenship, Charles H Hennekens
BACKGROUND: On a daily basis, healthcare providers, especially those dealing with terminally ill patients, such as hospice workers, witness how advance directives help ensure the wishes of patients. They also witness the deleterious consequences when patients fail to document the care they desire at their end of life. To the best of our knowledge there are no data concerning the prevalence of advance directives among hospice healthcare providers. We, therefore, explored the prevalence and factors influencing completion rates in a survey of hospice healthcare providers...
August 7, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28796902/spatio-temporal-variation-in-lifelong-telomere-dynamics-in-a-long-term-ecological-study
#8
Lewis G Spurgin, Kat Bebbington, Eleanor A Fairfield, Martijn Hammers, Jan Komdeur, Terry Burke, Hannah L Dugdale, David S Richardson
Understanding individual-level variation in response to the environment is fundamental to understanding life-history evolution and population dynamics. Telomeres, the protective caps at the ends of chromosomes, shorten in response to oxidative stress, and telomere shortening is correlated with reduced survival and lifespan. Investigating telomere dynamics may help us quantify individual variation in the costs experienced from social and ecological factors, and enhance our understanding of the dynamics of natural populations...
August 10, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28796370/a-highly-sensitive-bimodal-detection-of-amine-vapours-based-on-aggregation-induced-emission-of-1-2-dihydroquinoxaline-derivatives
#9
Parvej Alam, Nelson Lik Ching Leung, Huifang Su, Zijie Qiu, Ryan T K Kwok, Jacky W Y Lam, Ben Zhong Tang
The detection of food spoilage is a major concern in food safety as large amounts of food are transported globally. Direct analysis of food samples is often time-consuming and requires expensive analytical instrumentation. A much simpler and more cost-effective method for monitoring food fermentation is to detect biogenic amines generated as a by-product during food decomposition. In this work, a series of 1,2-dihydroquinoxaline derivatives (DQs) with aggregation-induced emission (AIE) characteristics were synthesized and their protonated forms, i...
August 10, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28795817/achieving-high-performances-of-nondoped-oleds-using-carbazole-and-diphenylphosphoryl-functionalized-ir-iii-complexes-as-active-components
#10
Hui-Ting Mao, Chun-Xiu Zang, Guo-Gang Shan, Hai-Zhu Sun, Wen-Fa Xie, Zhong-Min Su
Nondoped electroluminescent devices offer advantages over their doped counterparts such as good reproducibility, reduced phase separation between host and guest materials, and potential of lower-cost devices. However, low luminance efficiencies and significant roll-off values are longstanding issues for nondoped devices, and a rational design strategy for the preparation of efficient phosphors is highly desired. In this work, cyclometalated Ir(III) complexes 3CzIr(mtpy), 4CzIr(mtpy), 3POIr(mtpy), and 4POIr(mtpy) bearing carbazole (Cz) or diphenylphosphoryl (Ph2PO) groups substituted at different positions of 1,2-diphenyl-H-benzimidazole (HPBI) were designed and synthesized...
August 10, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28792740/selective-removal-of-nitrosamines-from-a-model-amine-carbon-capture-waterwash-using-low-cost-activated-carbon-sorbents
#11
Leland R Widger, Megan Combs, Amit R Lohe, Cameron A Lippert, Jesse G Thompson, Kunlei Liu
Nitrosamines generated in the amine solvent loop of post combustion carbon capture systems are potent carcinogens, and their emission could pose a serious threat to the environment or human health. Nitrosamine emission control strategies are critical for the success of amine-based carbon capture as the technology approaches industrial-scale deployment. Waterwash systems have been used to control volatile and aerosol emissions, including nitrosamines, from carbon capture plants, but it is still necessary to remove or destroy nitrosamines in the circulating waterwash to prevent their subsequent emission into the environment...
August 9, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28774278/cluster-randomised-trial-of-a-school-community-child-health-promotion-and-obesity-prevention-intervention-findings-from-the-evaluation-of-fun-n-healthy-in-moreland
#12
Elizabeth Waters, Lisa Gibbs, Maryanne Tadic, Obioha C Ukoumunne, Anthea Magarey, Anthony D Okely, Andrea de Silva, Christine Armit, Julie Green, Thea O'Connor, Britt Johnson, Boyd Swinburn, Lauren Carpenter, Graham Moore, Hannah Littlecott, Lisa Gold
BACKGROUND: Multi-level, longer-term obesity prevention interventions that focus on inequalities are scarce. Fun 'n healthy in Moreland! aimed to improve child adiposity, school policies and environments, parent engagement, health behaviours and child wellbeing. METHODS: All children from primary schools in an inner urban, culturally diverse and economically disadvantaged area in Victoria, Australia were eligible for participation. The intervention, fun 'n healthy in Moreland!, used a Health Promoting Schools Framework and provided schools with evidence, school research data and part time support from a Community Development Worker to develop health promoting strategies...
August 3, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28770690/optimal-mating-strategies-to-manage-a-heterozygous-advantage-major-gene-in-sheep
#13
J Raoul, I Palhière, J M Astruc, A Swan, J M Elsen
Some mutations (or 'major genes') have a desirable effect in heterozygous carriers but an undesirable effect in homozygous carriers. When these mutations affect a trait of significant economic importance, their eradication, depending on their effect and frequency, may be counterproductive. This is especially the case of major genes affecting the ovulation rate and thus the prolificacy in meat sheep populations. To manage such situations, a mating design based on the major genotypes of reproducers has to be optimized...
August 3, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28766552/recontacting-in-clinical-practice-the-views-and-expectations-of-patients-in-the-united-kingdom
#14
Daniele Carrieri, Sandi Dheensa, Shane Doheny, Angus J Clarke, Peter D Turnpenny, Anneke M Lucassen, Susan E Kelly
This paper explores the views and expectations of patients concerning recontacting in clinical practice. It is based on 41 semi-structured interviews conducted in the United Kingdom. The sample comprised patients or parents of patients: without a diagnosis; recently offered a test for a condition or carrier risk; with a rare condition; with a variant of unknown significance - some of whom had been recontacted. Participants were recruited both via the National Health Service (NHS) and through online, condition-specific support groups...
August 2, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28764782/pre-and-post-testing-counseling-considerations-for-the-provision-of-expanded-carrier-screening-exploration-of-european-geneticists-views
#15
Sandra Janssens, Davit Chokoshvili, Danya F Vears, Anne De Paepe, Pascal Borry
BACKGROUND: Carrier screening is generally performed with the aim of identifying healthy couples at risk of having a child affected with a monogenic disorder to provide them with reproductive options. Expanded carrier screening (ECS), which provides the opportunity for multiple conditions to be screened in one test, offers a more cost-effective and comprehensive option than screening for single disorders. However, implementation of ECS at a population level would have implications for genetic counseling practice...
August 1, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/28756787/brief-behavioural-activation-brief-ba-for-adolescent-depression-a-pilot-study
#16
Laura Pass, Carl W Lejuez, Shirley Reynolds
BACKGROUND: Depression in adolescence is a common and serious mental health problem. In the UK, access to evidence-based psychological treatments is limited, and training and employing therapists to deliver these is expensive. Brief behavioural activation for the treatment of depression (BATD) has great potential for use with adolescents and to be delivered by a range of healthcare professionals, but there is limited empirical investigation with this group. AIMS: To adapt BATD for depressed adolescents (Brief BA) and conduct a pilot study to assess feasibility, acceptability and clinical effectiveness...
July 31, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28750725/hydroxyapatite-collagen-scaffold-with-autologous-bone-marrow-aspirate-for-mandibular-condylar-reconstruction
#17
Debraj Howlader, U Vignesh, Dichen P Bhutia, Rahul Pandey, Sumit Kumar, Tulika Chandra, Divya Mehrotra
PURPOSE: This study was designed with the aim to assess the efficiency of hydroxyapatite/collagen (HA/Col) bio-scaffold with bone marrow aspirate (BMA) to reconstruct mandibular condyle in patients with temporomandibular joint (TMJ) ankylosis. MATERIALS AND METHODS: Seven pediatric patients with TMJ ankylosis, who visited our outpatient clinic and whose parents opted for this procedure, were included in this study. After a history and clinical examination for TMJ movements, computed tomography (CT) scans were obtained...
July 6, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28750507/improved-biosurfactant-production-by-bacillus-subtilis-spb1-mutant-obtained-by-random-mutagenesis-and-its-application-in-enhanced-oil-in-a-sand-system
#18
Mouna Bouassida, Semia Ellouze-Chaabouni, Dhouha Ghribi
Biosurfactants or microbial surfactants are surface-active biomolecules that are produced by a variety of microorganisms. Biodegradability and low toxicity have led to the intensification of scientific studies on a wide range of industrial applications for biosurfactants in the field of the environmental bioremediation as well as the petroleum industry and the enhanced oil recovery. However, the major bottlenecks in biosurfactant production are yield increase and cost reduction. Improving the bioindustrial production processes relies on many issues such as the use of cheap raw materials, the optimization of medium-culture conditions and selecting hyperproducing strains...
July 31, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28747694/decreasing-parental-task-specialization-promotes-conditional-cooperation
#19
Arne Iserbyt, Nolwenn Fresneau, Tiffanie Kortenhoff, Marcel Eens, Wendt Müller
How much to invest in parental care and by who remain puzzling questions fomented by a sexual conflict between parents. Negotiation that facilitates coordinated parental behaviour may be key to ease this costly conflict. However, understanding cooperation requires that the temporal and sex-specific variation in parental care, as well as its multivariate nature is considered. Using a biparental bird species and repeated sampling of behavioural activities throughout a major part of reproduction, we show a clear division of tasks between males and females in provisioning, brooding and foraging...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747533/species-integrity-enhanced-by-a-predation-cost-to-hybrids-in-the-wild
#20
P Anders Nilsson, Kaj Hulthén, Ben B Chapman, Lars-Anders Hansson, Jakob Brodersen, Henrik Baktoft, Jerker Vinterstare, Christer Brönmark, Christian Skov
Species integrity can be challenged, and even eroded, if closely related species can hybridize and produce fertile offspring of comparable fitness to that of parental species. The maintenance of newly diverged or closely related species therefore hinges on the establishment and effectiveness of pre- and/or post-zygotic reproductive barriers. Ecological selection, including predation, is often presumed to contribute to reduced hybrid fitness, but field evidence for a predation cost to hybridization remains elusive...
July 2017: Biology Letters
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