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Yang Jie, Huarui Zhu, Xia Cao, Yue Zhang, Ning Wang, Liqun Zhang, Zhong Lin Wang
Tactile sensing is of great importance in developing human-machine interface, remote control and security systems. Here, a self-triggered alarm system based on the one-piece triboelectric nanosensor (TENS) is reported. By using nitrocellulose (NC) membrane as the triboelectric material, the as-designed TENS can not only sensitively respond to physical contacts in a self-triggered mode, but also securely detect the third-level details of latent fingerprint. The self-triggered idea based on the triboelectric nanogenerator is compatible with intelligent interactive interface...
October 21, 2016: ACS Nano
Xiangao Zhang, Mingzhen Shao, Xiaoqi Zeng
In this paper, a type of compact nanosensor based on a metal-insulator-metal structure is proposed and investigated through cascading double asymmetric cavities, in which their metal cores shift along different axis directions. The cascaded asymmetric structure exhibits high transmission and sharp Fano resonance peaks via strengthening the mutual coupling of the cavities. The research results show that with the increase of the symmetry breaking in the structure, the number of Fano resonances increase accordingly...
October 18, 2016: Sensors
Yongming Guo, Lianfeng Zhang, Fengpu Cao, Yumin Leng
A facile, simple and low-cost approach for synthesizing highly fluorescent carbon quantum dots (CQDs) from thermal treatment of sustainable hair has been developed. The resultant CQDs exhibited strong blue emission with a quantum yield of 10.75%, excellent photostability and high stability in high salt conditions. As the fluorescence of CQDs can be efficiently quenched by Hg(2+), the CQDs can be constructed as a nanosensor for Hg(2+) with good sensitivity and selectivity. And as low as 10 nM Hg(2+) can be successfully detected...
October 20, 2016: Scientific Reports
Jun Hyuk Heo, Gyu Sung Yi, Byoung Sang Lee, Hui Hun Cho, Jin Woong Lee, Jung Heon Lee
Here, we report the development of an achromatic nanoparticle-based colorimetric sensor (achromatic nanosensor) with an on-off type color change that significantly enhances the color transition and increases the sensitivity of the sensor for naked-eye inspection. The achromatic nanosensor was prepared via a modified CMYK (CRYK) subtractive color model by combining DNA-functionalized gold nanoparticles (AuNPs-DNA), silver nanoparticles (AgNPs-DNA), and gold nanorods (AuNRs-DNA). The initially black-colored achromatic nanosensor not only allowed multiplexed detection by generating target-specific diverse color changes, but also improved the recognition of color changes by the naked eye...
October 20, 2016: Nanoscale
Chung-Hsuan Wu, Wei-Han Wang, Chien-Chong Hong, Kuo Chu Hwang
This paper presents a novel disposable breath-sensing tube with an on-tube single-nanowire (NW) sensor array for noninvasive, simple, and on-site detection of exhaled breath biomarkers. Although various noninvasive detection methods for lung cancer biomarkers in breath samples exist, they are unsuitable for self-diagnostics and immediate detection because they entail complicated handling procedures and are time intensive. In this study, we simulated, fabricated, and characterized disposable nanosensors by using single TiO2 and Ag NWs in flexible plastic tubes...
October 14, 2016: Lab on a Chip
Tuhina Banerjee, Shoukath Sulthana, Tyler Shelby, Blaze Heckert, Jessica Jewell, Kalee Woody, Vida Karimnia, James McAfee, Santimukul Santra
Enterohemorrhagic Escherichia coli O157:H7 presents a serious threat to human health and sanitation and is a leading cause in many food- and waterborne ailments. While conventional bacterial detection methods such as PCR, fluorescent immunoassays and ELISA exhibit high sensitivity and specificity, they are relatively laborious and require sophisticated instruments. In addition, these methods often demand extensive sample preparation and have lengthy readout times. We propose a simpler and more sensitive diagnostic technique featuring multiparametric magneto-fluorescent nanosensors (MFnS)...
October 14, 2016: ACS Infectious Diseases
Bongiwe Silwana, Charlton Van Der Horst, Emmanuel Iwuoha, Vernon Somerset
This study offers a brief review of the latest developments and applications of electrochemical sensors for the detection of Platinum Group Metals (PGMs) using electrochemical sensors. In particular, significant advances in electrochemical sensors made over the past decade and sensing methodologies associated with the introduction of nanostructures are highlighted. Amongst a variety of detection methods that have been developed for PGMs, nanoparticles offer the unrivaled merits of high sensitivity. Rapid detection of PGMs is a key step to promote improvement of the public health and individual quality of life...
August 15, 2016: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
Lauren E Jamieson, Victoria L Camus, Pierre O Bagnaninchi, Kate M Fisher, Grant D Stewart, William H Nailon, Duncan B McLaren, David J Harrison, Colin J Campbell
Use of multicellular tumor spheroids (MTS) to investigate therapies has gained impetus because they have potential to mimic factors including zonation, hypoxia and drug-resistance. However, analysis remains difficult and often destroys 3D integrity. Here we report an optical technique using targeted nanosensors that allows in situ 3D mapping of redox potential gradients whilst retaining MTS morphology and function. The magnitude of the redox potential gradient can be quantified as a free energy difference (ΔG) and used as a measurement of MTS viability...
September 22, 2016: Nanoscale
Lu Yang, Takatoki Yamamoto
Viruses have drawn much attention in recent years due to increased recognition of their important roles in virology, immunology, clinical diagnosis, and therapy. Because the biological and physical properties of viruses significantly impact their applications, quantitative detection of individual virus particles has become a critical issue. However, due to various inherent limitations of conventional enumeration techniques such as infectious titer assays, immunological assays, and electron microscopic observation, this issue remains challenging...
2016: Frontiers in Microbiology
George Kubas, William Rees, Jonathan Caguiat, David Asch, Diana Fagan, Pedro Cortes
The present research investigates the identification of amino acid sequences that selectively bind to a pentaerythritol tetranitrate (PETN) explosive surrogate. Through the use of a phage display technique and enzyme-linked immunosorbent assays (ELISA), a peptide library was tested against PETNH (pentaerythritol trinitrate hemisuccinate), a surrogate of PETN, in order to screen for those with amino acids having affinity toward the explosive. The use of the PETN surrogate allowed the immobilization of the target during the screening process, while retaining a chemical profile similar to that of PETN...
October 6, 2016: Biopolymers
Victoria L Camus, Grant D Stewart, William H Nailon, Duncan B McLaren, Colin J Campbell
Correction for 'Measuring the effects of fractionated radiation therapy in a 3D prostate cancer model system using SERS nanosensors' by Victoria L. Camus, et al., Analyst, 2016, 141, 5056-5061.
October 3, 2016: Analyst
Naveen Shamsudhin, Ye Tao, Jordi Sort, Bumjin Jang, Christian L Degen, Bradley J Nelson, Salvador Pané
Ferromagnetic nanowires are finding use as untethered sensors and actuators for probing micro- and nanoscale biophysical phenomena, such as for localized sensing and application of forces and torques on biological samples, for tissue heating through magnetic hyperthermia, and for microrheology. Quantifying the magnetic properties of individual isolated nanowires is crucial for such applications. Dynamic cantilever magnetometry is used to measure the magnetic properties of individual sub-500 nm diameter polycrystalline nanowires of Ni and Ni80 Co20 fabricated by template-assisted electrochemical deposition...
September 30, 2016: Small
Konstantin G Shevchenko, Vladimir R Cherkasov, Andrey A Tregubov, Petr I Nikitin, Maxim P Nikitin
Biomolecule-driven assembly of nanoparticles is a powerful and convenient approach for development of advanced nanosensors and theranostic agents with diverse "on-demand" composition and functionality. While a lot of research is being devoted to fabrication of such agents, the development of non-invasive analytical tools to monitor self-assembly/disassembly processes in real-time substantially lags behind. Here, we demonstrate the capabilities of localized surface plasmon resonance (SPR) phenomenon to study non-covalent interactions not just between plasmonic particles, but between gold nanoparticles (AuNP) and non-plasmonic ones...
September 12, 2016: Biosensors & Bioelectronics
W J Yu, H Sun, L Gao
We propose a mechanism to actively tune optical bistable behavior with the external magnetic field in nonlinear coated nanospheres with a magneto-optical (MO) shell and nonlinear metallic core. We show that such nanostructures can exhibit typical bistable phenomena near surface plasmon resonant wavelengths, which can be modified through the external magnetic fields B. We demonstrate numerically that the optical bistability exists only when the volume fraction η of the metallic core is larger than a critical one η<sub>c</sub>...
September 19, 2016: Optics Express
Feng Tang, Pierre-Michel Adam, Salim Boutami
Surface-enhanced Raman spectroscopy (SERS) is widely used to sensitively detect molecules or markers in pharmacology, biology, etc. We study numerically the possibility to realize SERS detections directly on a photonic chip. It is presented that a SERS sensor created by combining a gold slot waveguide and a Si<sub>3</sub>N<sub>4</sub> strip waveguide can be designed to excite enhanced Raman effects and extract their scattering signals on a chip. Using 3D finite-difference time-domain simulations, the SERS processes, excitation of surface plasmon in slots and radiation of induced Raman dipoles, are analyzed to simulate SERS detections in reality...
September 19, 2016: Optics Express
Sabrina Simoncelli, Eva-Maria Roller, Patrick Urban, Robert Schreiber, Andrew J Turberfield, Tim Liedl, Theobald Lohmueller
DNA origami is a powerful approach for assembling plasmonic nanoparticle dimers and Raman dyes with high yields and excellent positioning control. Here we show how optothermal induced shrinking of a DNA origami template can be employed to control the gap sizes between two 40 nm gold nanoparticles in a range of 1 nm - 2 nm. The high field confinement achieved with this optothermal approach was demonstrated by detection of surface-enhanced Raman spectroscopy (SERS) signals from single molecules that are precisely placed within the DNA origami template that spans the nanoparticle gap...
September 20, 2016: ACS Nano
Unni Sivasankaran, Soumya T Cyriac, Shalini Menon, Krishnapillai Girish Kumar
A nanosensor with fluorometric readout based on L-cysteine capped cadmium sulphide quantum dots for discriminative detection and determination of Brilliant blue FCF (BB) (in 0.5 M Tris buffer solution of pH 9.5) over other synthetic food colourants is developed. Mechanism of the nanosensor is based on inner filter effect (IFE). The addition of BB into quantum dot solution might induce the quenching of fluorescence. The nanosensor described in this report reveals its simplicity and flexibility due to less laborious and more cost-effective synthesis...
September 18, 2016: Journal of Fluorescence
Zari Hooshyar, Ghasem Rezanejade Bardajee
In this study, we describe the synthesis of a new quantum dots (QDs) by embedding glutathione capped CdTe/ZnS QDs into cationic starch biopolymer (CS-GSH-CdTe/ZnS QDs). The fluorescence intensity of prepared QDs was significantly enhanced. When QDs interacted with rifampicin, the fluorescence intensity of the CS-GSH-CdTe/ZnS QDs was highly quenched compared with GSH-CdTe/ZnS QDs. Based on the above, a new fluorescent nanosensor for simple, sensitive and selective detection of rifampicin was developed. The fluorescence quenching was well described by the typical Stern-Volmer equation...
September 8, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Jung-Rok Lee, D James Haddon, Nidhi Gupta, Jordan V Price, Grace M Credo, Vivian K Diep, Kyunglok Kim, Drew A Hall, Emily C Baechler, Michelle Petri, Madoo Varma, Paul J Utz, Shan X Wang
Autoantibodies are a hallmark of autoimmune diseases such as lupus and have the potential to be used as biomarkers for diverse diseases, including immunodeficiency, infectious disease, and cancer. More precise detection of antibodies to specific targets is needed to improve diagnosis of such diseases. Here, we report the development of reusable peptide microarrays, based on giant magnetoresistive (GMR) nanosensors optimized for sensitively detecting magnetic nanoparticle labels, for the detection of antibodies with a resolution of a single post-translationally modified amino acid...
September 16, 2016: ACS Nano
Zhihe Qing, Lina Hou, Le Yang, Lixuan Zhu, Sheng Yang, Jing Zheng, Ronghua Yang
It is well-known that cyanide ion (CN(-)) is a hypertoxic anion, which can cause adverse effects in both the environment and living beings; thus, it is highly desirable to develop strategies for detecting CN(-), especially in water and food. However, due to the short half-life of free cyanide, long analysis time and/or interference from other competitive ions are general challenges for accurate monitoring of CN(-). In this work, through the investigation on the sequence-dependent optical interaction of DNA-CuNPs with the fluorophore (e...
October 4, 2016: Analytical Chemistry
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