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https://www.readbyqxmd.com/read/28231025/rabit-ii-implementation-of-a-high-throughput-micronucleus-biodosimetry-assay-on-commercial-biotech-robotic-systems
#1
Mikhail Repin, Sergey Pampou, Charles Karan, David J Brenner, Guy Garty
We demonstrate the use of high-throughput biodosimetry platforms based on commercial high-throughput/high-content screening robotic systems. The cytokinesis-block micronucleus (CBMN) assay, using only 20 μl whole blood from a fingerstick, was implemented on a PerkinElmer cell::explorer and General Electric IN Cell Analyzer 2000. On average 500 binucleated cells per sample were detected by our FluorQuantMN software. A calibration curve was generated in the radiation dose range up to 5.0 Gy using the data from 8 donors and 48,083 binucleated cells in total...
February 23, 2017: Radiation Research
https://www.readbyqxmd.com/read/28230003/risk-stratification-for-disease-progression-in-pt3-prostate-cancer-after-robot-assisted-radical-prostatectomy
#2
Jeong Hee Hong, Young Suk Kwon, Isaac Yi Kim
The aim of this study is to identify optimal patients for adjuvant radiation therapy (ART) in pT3 prostate cancer. The role of ART for patients with adverse pathologic features after radical prostatectomy (RP) has been demonstrated, but over- or under-treatment remains a significant concern. Two-hundred and five patients with pT3N0M0 who underwent robot-assisted RP without ART were analyzed. Multivariate Cox proportional regression analyses were used to identify predictors of biochemical recurrence (BCR) and clinical progression (CP)...
February 21, 2017: Asian Journal of Andrology
https://www.readbyqxmd.com/read/28229461/how-different-is-a-3d-printed-replica-from-a-conspecific-in-the-eyes-of-a-zebrafish
#3
Tommaso Ruberto, Giovanni Polverino, Maurizio Porfiri
Robotics is emerging as a promising tool for aiding research on animal behavior. The possibility of generating customizable, controllable, and standardized robotic stimuli has been demonstrated through a number of behavioral assays, involving vertebrates and invertebrates. However, the specific appraisal of the nature of robotic stimuli is currently lacking. Here, we attempt to evaluate this aspect in zebrafish, through a within-subject design in which experimental subjects are faced with three experimental conditions...
February 22, 2017: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/28229441/-robotic-systems-for-gait-re-education-in-cases-of-spinal-cord-injury-a-systematic-review
#4
T Gandara-Sambade, M Fernandez-Pereira, A Rodriguez-Sotillo
INTRODUCTION: The evidence underlying robotic body weight supported treadmill training in patients with spinal cord injury remains poorly characterized. AIM: To perform a qualitative systematic review on the efficacy of this therapy. PATIENTS AND METHODS: A search on PubMed, CINAHL, Cochrane Library and PEDro was performed from January 2005 to April 2016. The references in these articles were also reviewed to find papers not identified with the initial search strategy...
March 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28229210/robotic-kidney-transplantation-one-year-after-the-beginning
#5
Alberto Breda, Angelo Territo, Lluis Gausa, Oscar Rodríguez-Faba, Jorge Caffaratti, Javier Ponce de León, Lluis Guirado, Carme Facundo, Marco Guazzieri, Andrea Guttilla, Humberto Villavicencio
INTRODUCTION: Kidney transplantation (KT) is the preferred treatment for patients with end-stage renal disease (ESRD). To reduce the morbidity of the open surgery, a robotic-assisted approach has been recently introduced. Our aim is to evaluate surgical and functional results on 17 cases of robotic-assisted kidney transplantation (RAKT) performed at the same institution. MATERIALS AND METHODS: From July 2015 to June 2016, we performed 17 cases of RAKT from living donors in pre-emptive patients, who underwent laparoscopic nephrectomy...
February 22, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28228582/multi-digit-force-control-during-unconstrained-grasping-in-response-to-object-perturbations
#6
Abdeldjallil Naceri, Alessandro Moscatelli, Robert Haschke, Helge Ritter, Marco Santello, Marc O Ernst
Because of the complex anatomy of the human hand, in the absence of external constraints a large number of postures and force combinations can be used to attain a stable grasp. Motor synergies provide a viable strategy to solve this problem of motor redundancy. In this study, we exploited the technical advantages of an innovative sensorized object to study unconstrained hand grasping within the theoretical framework of motor synergies. Participants were required to grasp, lift, and hold the sensorized object...
February 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28227970/combining-a-hybrid-robotic-system-with-a-bain-machine-interface-for-the-rehabilitation-of-reaching-movements-a-case-study-with-a-stroke-patient
#7
F Resquin, J Ibanez, J Gonzalez-Vargas, F Brunetti, I Dimbwadyo, S Alves, L Carrasco, L Torres, Jose Luis Pons, F Resquin, J Ibañez, J Gonzalez-Vargas, F Brunetti, I Dimbwadyo, S Alves, L Carrasco, L Torres, Jose Luis Pons, S Alves, Jose Luis Pons, F Brunetti, J Gonzalez-Vargas, F Resquin, I Dimbwadyo, L Carrasco, L Torres, J Ibanez
Reaching and grasping are two of the most affected functions after stroke. Hybrid rehabilitation systems combining Functional Electrical Stimulation with Robotic devices have been proposed in the literature to improve rehabilitation outcomes. In this work, we present the combined use of a hybrid robotic system with an EEG-based Brain-Machine Interface to detect the user's movement intentions to trigger the assistance. The platform has been tested in a single session with a stroke patient. The results show how the patient could successfully interact with the BMI and command the assistance of the hybrid system with low latencies...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227966/real-time-evaluation-of-a-myoelectric-control-method-for-high-level-upper-limb-amputees-based-on-homologous-leg-movements
#8
Kenneth R Lyons, Sanjay S Joshi, Kenneth R Lyons, Sanjay S Joshi, Sanjay S Joshi, Kenneth R Lyons
Electromyography-based gesture classification methods for control of advanced upper limb prostheses are limited either to individuals with amputations distal to the elbow or to those willing to undergo targeted muscle reinnervation surgery. Based on the natural similarity between gestures of the lower leg and the arm and on established methods in electromyography-based gesture classification, we propose a noninvasive system with which users control an upper limb prosthesis via homologous movements of the leg and foot...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227942/unified-phase-variables-of-relative-degree-two-for-human-locomotion
#9
Dario J Villarreal, Robert D Gregg, Dario J Villarreal, Robert D Gregg, Robert D Gregg, Dario J Villarreal
A starting point to achieve stable locomotion is synchronizing the leg joint kinematics during the gait cycle. Some biped robots parameterize a nonlinear controller (e.g., input-output feedback linearization) whose main objective is to track specific kinematic trajectories as a function of a single mechanical variable (i.e., a phase variable) in order to allow the robot to walk. A phase variable capable of parameterizing the entire gait cycle, the hip phase angle, has been used to control wearable robots and was recently shown to provide a robust representation of the phase of human gait...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227915/relationship-between-magnitude-of-applied-torque-in-pre-swing-phase-and-gait-change-for-prevention-of-trip-in-elderly-people
#10
Tamon Miyake, Mariko Tsukune, Yo Kobayashi, Shigeki Sugano, Masakatsu G Fujie, Tamon Miyake, Mariko Tsukune, Yo Kobayashi, Shigeki Sugano, Masakatsu G Fujie, Shigeki Sugano, Tamon Miyake, Masakatsu G Fujie, Yo Kobayashi, Mariko Tsukune
Elderly people are at risk of tripping because of their narrow range of articular motion. To avoid tripping, gait training that improves their range of articular motion would be beneficial. In this study we propose a gait-training robot that applies a torque during the pre-swing phase to achieve this goal. We investigated the relationship between magnitude of applied torque and change in the range of knee-articular motion while walking before and after the application of this torque. We developed a wearable robot and carried out an experiment on human participants in which a motor pulls a string embedded on the robotic frame, applying torque in the pre-swing phase for a period of 20 [s]...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227908/a-boolean-approach-to-bacterial-chemotaxis
#11
Anuj Deshpande, Sibendu Samanta, Haimabati Das, Ritwik Kumar Layek, Anuj Deshpande, Sibendu Samanta, Haimabati Das, Ritwik Kumar Layek, Sibendu Samanta, Anuj Deshpande, Haimabati Das, Ritwik Kumar Layek
Bacterium such as Escherichia coli (E. coli) show biased Brownian motion in different chemical concentration gradients. This chemical sensitive motility or chemotaxis has gained considerable interest among scientists for some remarkable features such as chemo-sensory dynamic range, adaptation, diffusion and drift. A Boolean model of the whole chemotaxis process has been developed in this manuscript. The response of the circuit is in accordance with the experimental results available in the literature, providing indirect validation of the model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227837/progressive-abduction-loading-therapy-targeting-flexion-synergy-to-regain-reaching-function-in-chronic-stroke-preliminary-results-from-an-rct
#12
Michael D Ellis, Carolina Carmona, Justin Drogos, Stuart Traxel, Julius P A Dewald, Michael D Ellis, Carolina Carmona, Justin Drogos, Stuart Traxel, Julius P A Dewald, Stuart Traxel, Michael D Ellis, Carolina Carmona, Julius P A Dewald, Justin Drogos
Reaching function is impaired following stroke due to abnormal coupling of shoulder abduction and elbow flexion. This phenomenon is commonly referred to as flexion synergy, loss of independent joint control, or impaired joint individuation. We have been successful in treating individuals with chronic stroke with moderate to severe motor impairments through the employment of targeted rehabilitation robotics and identified progressive abduction loading as a key element to the rehabilitation of reaching. Here we expand upon the investigation of progressive abduction loading therapy by testing two variants of the exercise in a larger sample and including a 3-month follow-up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227836/exerciser-for-rehabilitation-of-the-arm-era-development-and-unique-features-of-a-3d-end-effector-robot
#13
Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Philippe-Olivier Provost, Dominic Letourneau, Maxime Dupuis, Marie-Helene Milot, Francois Michaud, Mathieu Hamel, Julien Bernier-Ouellet, Simon Briere
Stroke is one of the leading causes of disability worldwide. Consequently, many stroke survivors exhibit difficulties undergoing voluntary movement in their affected upper limb, compromising their functional performance and level of independence. To minimize the negative impact of stroke disabilities, exercises are recognized as a key element in post-stroke rehabilitation. In order to provide the practice of exercises in a uniform and controlled manner as well as increasing the efficiency of therapists' interventions, robotic training has been found, and continues to prove itself, as an innovative intervention for post-stroke rehabilitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227808/adaptive-decoding-using-local-field-potentials-in-a-brain-machine-interface
#14
Rosa So, Camilo Libedinsky, Kai Keng Ang, Wee Chiek Clement Lim, Kyaw Kyar Toe, Cuntai Guan, Rosa So, Camilo Libedinsky, Kai Keng Ang, Wee Chiek Clement Lim, Kyaw Kyar Toe, Cuntai Guan, Rosa So, Wee Chiek Clement Lim, Kai Keng Ang, Kyaw Kyar Toe, Camilo Libedinsky, Cuntai Guan
Brain-machine interface (BMI) systems have the potential to restore function to people who suffer from paralysis due to a spinal cord injury. However, in order to achieve long-term use, BMI systems have to overcome two challenges - signal degeneration over time, and non-stationarity of signals. Effects of loss in spike signals over time can be mitigated by using local field potential (LFP) signals for decoding, and a solution to address the signal non-stationarity is to use adaptive methods for periodic recalibration of the decoding model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227799/classification-of-forearm-and-finger-motions-using-electromyogram-and-arm-shape-changes
#15
Yuhei Kamei, Shima Okada, Yuhei Kamei, Shima Okada, Yuhei Kamei, Shima Okada
Robot arms for humanoid are widely developed for medical, welfare and education use. Surface electromyogram (sEMG) signals which are the electrical signals obtained from surface of human skin using electrodes have been mainly used for classification of hand motions. However, it is difficult to classify detailed motions such as finger motions and wrist pronation or supination. Moreover, Kinect is an integration sensor device which can capture human joints movement. It also has been widely used for recognition of body motions in many fields...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227797/human-robot-collaborated-path-planning-for-bevel-tip-needle-steering-in-simulated-human-environment
#16
Jing Xiong, Zeyang Xia, Yangzhou Gan, Jing Xiong, Zeyang Xia, Yangzhou Gan, Yangzhou Gan, Jing Xiong, Zeyang Xia
Clinical Application of linear percutaneous needle insertion is restricted due to issues such as limited path and deflection. Thus steering of flexible needle is critical demanded in the clinic. Previous studies tended to use autonomous methods to conduct path planning for needle steering. However, these methods had very limited adaptabilities, and they also decreased the human operator's domination of the operation, as clinically required. In this case, teleoperation has been an option, while in complicated environments sole teleoperation is not sufficient for a human operator to generate multi-curved insertion path...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227689/robotic-system-with-multiplex-power-transmission-for-mri-guided-percutaneous-interventions
#17
Yang Wang, Sungmin Kim, Everette C Burdette, Peter Kazanzides, Iulian Iordachita, Yang Wang, Sungmin Kim, Everette C Burdette, Peter Kazanzides, Iulian Iordachita, Sungmin Kim, Peter Kazanzides, Everette C Burdette, Iulian Iordachita, Yang Wang
In minimally invasive prostate percutaneous interventions, Magnetic Resonance Imaging (MRI) compatible robotic assistive systems developed over the years tend to have multiple degrees of freedom (DOF) to accomplish complex surgical tasks. This paper presents a novel design of an MRI-compatible transmission that allows one driving motor to control a multiplexed DOF robot system. The transmission could reduce the number of motors in the system, while maintaining the functionality of the system, by controlling each motion sequentially rather than simultaneously...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227685/graphical-user-interface-for-a-robotic-workstation-in-a-surgical-environment
#18
A Bielski, C P Lohmann, M Maier, D Zapp, M A Nasseri, A Bielski, C P Lohmann, M Maier, D Zapp, M A Nasseri, M A Nasseri, M Maier, D Zapp, C P Lohmann, A Bielski
Surgery using a robotic system has proven to have significant potential but is still a highly challenging task for the surgeon. An eye surgery assistant has been developed to eliminate the problem of tremor caused by human motions endangering the outcome of ophthalmic surgery. In order to exploit the full potential of the robot and improve the workflow of the surgeon, providing the ability to change control parameters live in the system as well as the ability to connect additional ancillary systems is necessary...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227672/robot-assisted-microsurgical-forceps-with-haptic-feedback-for-transoral-laser-microsurgery
#19
Nikhil Deshpande, Manish Chauhan, Claudio Pacchierotti, Domenico Prattichizzo, Darwin G Caldwell, Leonardo S Mattos, Nikhil Deshpande, Manish Chauhan, Claudio Pacchierotti, Domenico Prattichizzo, Darwin G Caldwell, Leonardo S Mattos, Darwin G Caldwell, Leonardo S Mattos, Nikhil Deshpande, Domenico Prattichizzo, Manish Chauhan, Claudio Pacchierotti
In this paper, a novel, motorized, multi-degrees-of-freedom (DoF), microsurgical forceps tool is presented, which is based on a master-slave teleoperation architecture. The slave device is a 7-DoF manipulator with: (i) 6-DoF positioning and orientation, (ii) 1 open/close gripper DoF; and (iii) an integrated force/torque sensor for tissue grip-force measurement. The master device is a 7-DoF haptic interface which teleoperates the slave device, and provides haptic feedback in its gripper interface. The combination of the device and the surgeon interface replaces the manual, hand-held device providing easy-to-use and ergonomic tissue control, simplifying the surgical tasks...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227665/hardware-design-for-a-cable-free-fully-insertable-wireless-laparoscopic-robotic-camera
#20
Ning Li, Gregory J Mancini, Jindong Tan, Ning Li, Gregory J Mancini, Jindong Tan, Gregory J Mancini, Ning Li, Jindong Tan
The field of insertable laparoscopic robotic camera is gaining increasing attentions from researchers, surgeons, and also patients. Although many insertable laparoscope prototypes have been introduced, few of them get rid of the encumbrance tethering cable. In this paper, we proposed a hardware architecture for a magnetic actuated robotic surgical (MARS) camera, which facilitates a cable-free fully insertable laparoscopic surgical robotic camera with adequate in-vivo mobility. Modular design and preliminary test of on-board functional payloads have shown feasibility of a cable-free insertable wireless laparoscopic surgical camera based on off-the-shelf electronics and industrial wireless standards operating in ISM frequency bands at 2...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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