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Seasonal affective disorder

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https://www.readbyqxmd.com/read/30002811/severity-of-allergic-rhinitis-impacts-sleep-and-anxiety-results-from-a-large-spanish-cohort
#1
R Muñoz-Cano, P Ribó, G Araujo, E Giralt, J Sanchez-Lopez, A Valero
Background: Allergic rhinitis (AR) is a highly prevalent disease that generates high social and health care costs and also has a significant effect on quality of life and quality of sleep. It has also been related to some psychological disorders like anxiety or depression. Objective: To evaluate anxiety, depression, and quality of sleep and life alteration in a group of patients with perennial AR compared to a group of seasonal AR patients. Methods: Six-hundred seventy adults (> 18 years) with perennial and seasonal AR were recruited consecutively in 47 centers in Spain...
2018: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/29913309/the-causes-and-consequences-of-variation-in-human-cytokine-production-in-health
#2
REVIEW
Melanie Schirmer, Vinod Kumar, Mihai G Netea, Ramnik J Xavier
Cytokines are important cell-signaling molecules that activate and modulate immune responses. Major factors influencing cytokine variation in healthy individuals are host genetics, non-heritable factors and the microbiome. Genetic variation accounts for a significant part of heterogeneity in cytokine production by peripheral blood mononuclear cells. Variation in cytokines such as IL-6 and IL-6Ra is strongly influenced by heritability, suggesting an evolutionarily pressure for their genetic regulation that potentially contributes to differences in immune responsiveness between human populations...
June 15, 2018: Current Opinion in Immunology
https://www.readbyqxmd.com/read/29888167/chronotype-and-psychiatric-disorders
#3
REVIEW
Liia Kivelä, Marinos Rodolfos Papadopoulos, Niki Antypa
Purpose of Review: Chronotype, reflecting interindividual differences in daily activity patterns and sleep-wake cycles, is intrinsically connected with well-being. Research indicates increased risk of many adverse mental health outcomes for evening-type individuals. Here, we provide an overview of the current evidence available on the relationship between chronotype and psychiatric disorders. Recent Findings: The association between eveningness and depression is well established cross-sectionally, with preliminary support from longitudinal studies...
2018: Current Sleep Medicine Reports
https://www.readbyqxmd.com/read/29875535/sickness-behavior-and-seasonal-affective-disorder-an-immunological-perspective-of-depression
#4
Pooja Patnaik Kuppili, Nivedhitha Selvakumar, Vikas Menon
We describe a case of 45-year-old female suffering from chronic hepatitis B and bronchial asthma who presented with symptoms of seasonal affective disorder and sickness behavior. The case report illustrates syndromal and sub syndromal presentations of depression such as sickness behavior in support of "malaise theory of depression" from psychoneuroimmunological perspective. The current case depicts the complex interplay of inflammatory physical illness, medication and manifestations of depression in an individual case...
May 2018: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29857893/females-have-stronger-neurogenic-response-than-males-after-non-specific-nasal-challenge-in-patients-with-seasonal-allergic-rhinitis
#5
Dejan Tomljenovic, Tomislav Baudoin, Zeljka Bukovec Megla, Goran Geber, Glenis Scadding, Livije Kalogjera
Epidemiological studies show female predominance in the prevalence of non- allergic rhinitis (NAR) and local allergic rhinitis (LAR). Experimental studies show female patients with allergic rhinitis (AR) demonstrate higher levels of sensitivity to irritants and airway hyperresponsiveness than males. Bronchial asthma shows female predominance in post-puberty patients, and gender interaction with severe asthma endotypes. Fibromyalgia, chronic fatigue syndrome, migraine and chronic cough, syndromes, which are commonly related to neurokinin substance P (SP) in the literature, also show strong female predominance...
July 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29843023/differences-in-sleep-functioning-between-individuals-with-seasonal-affective-disorder-and-major-depressive-disorder-in-finland
#6
Isabel Morales-Muñoz, Seppo Koskinen, Timo Partonen
BACKGROUND: Sleep problems are commonly reported in seasonal affective disorder (SAD) and major depressive disorder (MDD). However, the specific characteristics of sleep difficulties differ. Frequent sleep problems in MDD are insomnia and night awakenings, whereas SAD patients complain of hypersomnia and daytime sleepiness. No previous studies have reported differences in sleep functioning between these two disorders. METHODS: We interviewed 4554 subjects from the Health 2011 survey and included 4153 individuals in this study...
April 25, 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29790788/no-association-of-moon-phase-with-stroke-occurrence
#7
Jori O Ruuskanen, Jussi O T Sipilä, Päivi Rautava, Ville Kytö
Stroke occurrence shows strong correlations with sleep disorders and even subtle sleep disturbances have been shown to affect ischemic stroke (IS) occurrence. Chronobiology also exerts effects, like the morning surge in IS occurrence. Lunar cycles have also been shown to affect sleep and other physiological processes, but studies on moon phases and its possible association with occurrence of stroke are rare and nonconclusive. Therefore, we studied the effects of moon phases on stroke hospitalizations and in-hospital mortality nationwide in Finland in 2004-2014...
May 23, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29725308/the-exposure-to-different-photoperiods-strongly-modulates-the-glucose-and-lipid-metabolisms-of-normoweight-fischer-344-rats
#8
Roger Mariné-Casadó, Cristina Domenech-Coca, Josep M Del Bas, Cinta Bladé, Lluís Arola, Antoni Caimari
Seasonal variations in day length trigger clear changes in the behavior, growth, food intake, and reproductive status of photoperiod-sensitive animals, such as Fischer 344 rats. However, there is little information about the effects of seasonal fluctuations in day length on glucose and lipid metabolisms and their underlying mechanisms in this model. To gain knowledge on these issues, three groups of male Fischer 344 rats were fed with a standard diet and exposed to different photoperiods for 14 weeks: normal photoperiod (L12, 12 h light/day), long photoperiod (L18, 18 h light/day), and short photoperiod (L6, 6 h light/day)...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29723630/quantitative-market-survey-of-non-woody-plants-sold-at-kariakoo-market-in-dar-es-salaam-tanzania
#9
Chantal Posthouwer, Sarina Veldman, Siri Abihudi, Joseph N Otieno, Tinde R van Andel, Hugo J de Boer
ETHNOPHARMACOLOGICAL RELEVANCE: In Tanzania, traditional medicine plays a significant role in health care and local economies based on the harvesting, trade and sale of medicinal plant products. The majority of this plant material is said to originate from wild sources, and both traditional healers and vendors are concerned about the increasing scarcity of certain species. AIM OF THE STUDY: A market survey of non-powdered, non-woody medicinal plants was conducted at Kariakoo Market in Dar es Salaam, the major hub for medicinal plant trade in Tanzania, to assess sustainability of traded herbal medicine...
August 10, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29718372/defining-the-impact-of-melanopsin-missense-polymorphisms-using-in-vivo-functional-rescue
#10
Jessica Rodgers, Steven Hughes, Carina A Pothecary, Laurence A Brown, Doron G Hickey, Stuart N Peirson, Mark W Hankins
Melanopsin (OPN4) is an opsin photopigment expressed within intrinsically photosensitive retinal ganglion cells (ipRGCs) that mediate non-image forming (NIF) responses to light. Two single nucleotide polymorphisms (SNPs) in human melanopsin (hOPN4), Pro10Leu and Thr394Ile, have recently been associated with abnormal NIF responses to light, including Seasonal Affective Disorder. It has been suggested these behavioural changes are due to altered melanopsin signalling. However, there is currently no direct evidence to support this...
April 30, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29692622/identifying-agents-triggering-bronchiolitis-in-the-state-of-qatar
#11
Mohamed A Hendaus, Ahmed H Alhammadi, Prem Chandra, Eshan Muneer, Mohamed S Khalifa
Background: Bronchiolitis is considered as the most frequent lower respiratory tract infection in infants and young children. This disorder is marked by acute inflammation, edema, damage of epithelial cells lining small airways, and augmentation of mucus production. Objective: The goal of the study was to identify agents triggering bronchiolitis in the State of Qatar. Materials and methods: A cross-sectional retrospective study was performed at Hamad Medical Corporation, the only tertiary and academic medical center in the State of Qatar...
2018: International Journal of General Medicine
https://www.readbyqxmd.com/read/29674191/seasonality-of-hypertensive-disorders-of-pregnancy-a-south-australian-population-study
#12
Petra E Verburg, Gus A Dekker, Graeme Tucker, Wendy Scheil, Jan Jaap H M Erwich, Claire T Roberts
OBJECTIVES: To investigate the seasonal variation of hypertensive disorders of pregnancy (HDP) in South Australia. STUDY DESIGN: Retrospective population study including all 107,846 liveborn singletons during 2007-2014 in South Australia. Seasonality in incidence of HDP in relation to estimated date of conception (eDoC) and date of birth (DoB) were examined using Fourier series analysis. MAIN OUTCOME MEASURES: Seasonality of HDP in relation to eDoC and DoB...
April 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29659120/patterns-of-depressive-symptom-remission-during-the-treatment-of-seasonal-affective-disorder-with-cognitive-behavioral-therapy-or-light-therapy
#13
Jonah Meyerhoff, Michael A Young, Kelly J Rohan
BACKGROUND: To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light therapy (LT). METHOD: One hundred seventy-seven adults with SAD in a depressive episode were randomized to 6-weeks of CBT-SAD (n = 88) or LT (n = 89)...
May 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29614896/modeling-strengthens-molecular-link-between-circadian-polymorphisms-and-major-mood-disorders
#14
Amanda R Liberman, Lumbardh Halitjaha, Ahmet Ay, Krista K Ingram
Anxiety and other mood disorders, such as major depressive disorder (MDD) and seasonal affective disorder (SAD), affect nearly one-fifth of the global population and disproportionately affect young adults. Individuals affected by mood disorders are frequently plagued by sleep and circadian problems, and recent genetic studies provide ample support for the association of circadian and sleep syndromes with depression and anxiety. Mathematical modeling has been crucial in understanding some of the essential features of the mammalian circadian clock and is now a vital tool for dissecting how circadian genes regulate the molecular mechanisms that influence mood...
June 2018: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29593784/precision-light-for-the-treatment-of-psychiatric-disorders
#15
REVIEW
Sevag Kaladchibachi, Fabian Fernandez
Circadian timekeeping can be reset by brief flashes of light using stimulation protocols thousands of times shorter than those previously assumed to be necessary for traditional phototherapy. These observations point to a future where flexible architectures of nanosecond-, microsecond-, and millisecond-scale light pulses are compiled to reprogram the brain's internal clock when it has been altered by psychiatric illness or advanced age. In the current review, we present a chronology of seminal experiments that established the synchronizing influence of light on the human circadian system and the efficacy of prolonged bright-light exposure for reducing symptoms associated with seasonal affective disorder...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29575228/herbal-medicines-in-the-treatment-of-psychiatric-disorders-10-year-updated-review
#16
REVIEW
Jerome Sarris
This paper provides a 10-year update of the 2007 systematic review of herbal medicines studied in a broad range of psychiatric disorders, including depression, anxiety, obsessive-compulsive, seasonal affective, bipolar, psychotic, phobic, somatoform, and attention-deficit hyperactivity disorders. Ovid Medline, PubMed, and the Cochrane Library were searched for herbal medicines with both pharmacological and clinical evidence of psychotropic activity. This updated review now covers clinical trial evidence for 24 herbal medicines in 11 psychiatric disorders...
March 25, 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29560509/light-rescues-circadian-behavior-and-brain-dopamine-abnormalities-in-diurnal-rodents-exposed-to-a-winter-like-photoperiod
#17
Jacob Itzhacki, Daniel Clesse, Yannick Goumon, Eus J Van Someren, Jorge Mendoza
Seasonal affective disorder (SAD), beyond mood changes, is characterized by alterations in daily rhythms of behavior and physiology. The pathophysiological conditions of SAD involve changes in day length and its first-line treatment is bright light therapy. Animal models using nocturnal rodents have been studied to elucidate the neurobiological mechanisms of depression, but might be ill suited to study the therapeutic effects of light in SAD since they exhibit light-aversive responses. Here Arvicanthis ansorgei, a diurnal rodent, was used to determine behavioral, molecular and brain dopamine changes in response to exposure to a winter-like photoperiod consisting of a light-dark cycle with 8 h of light, under diminished light intensity, and 16 h of darkness...
March 20, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29498416/workplace-lighting-for-improving-alertness-and-mood-in-daytime-workers
#18
REVIEW
Daniela V Pachito, Alan L Eckeli, Ahmed S Desouky, Mark A Corbett, Timo Partonen, Shantha Mw Rajaratnam, Rachel Riera
BACKGROUND: Exposure to light plays a crucial role in biological processes, influencing mood and alertness. Daytime workers may be exposed to insufficient or inappropriate light during daytime, leading to mood disturbances and decreases in levels of alertness. OBJECTIVES: To assess the effectiveness and safety of lighting interventions to improve alertness and mood in daytime workers. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, seven other databases; ClinicalTrials...
March 2, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29477098/the-effects-of-low-intensity-narrow-band-blue-light-treatment-compared-to-bright-white-light-treatment-in-seasonal-affective-disorder
#19
Ybe Meesters, Wianne B Duijzer, Vanja Hommes
BACKGROUND: Ever since a new photoreceptor was discovered with a highest sensitivity to 470-490 nm blue light, it has been speculated that blue light has some advantages in the treatment of Seasonal Affective Disorder (SAD) over more traditional treatments. In this study we compared the effects of exposure to narrow-band blue light (BLUE) to those of broad-wavelength white light (BLT) in the treatment of SAD. METHODS: In a 15-day design, 45 patients suffering from SAD completed 30-min sessions of light treatment on 5 consecutive days...
May 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29475230/association-of-g-protein-%C3%AE-3-subunit-c825t-polymorphism-with-seasonal-variations-in-mood-and-behavior
#20
Yoon-Ju Nam, Chul-Hyun Cho, Leen Kim, Heon-Jeong Lee
OBJECTIVE: Seasonal affective disorder and seasonal changes in mood and behavior are associated with several genes that regulate circadian rhythms. In this study, we investigated the relationship between the C825T polymorphism of the G-protein β3 subunit and seasonal variations in mood and behavior in a young healthy Korean population. METHODS: A total of 507 young Korean participants were recruited through a newspaper advertisement, and their seasonality was evaluated by the Korean version of the Seasonal Pattern Assessment Questionnaire to assess the global seasonality score (GSS)...
February 2018: Psychiatry Investigation
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