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Seasonal affective disorder

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https://www.readbyqxmd.com/read/28432995/eye-disorder-differentiates-seasonality-outcomes-in-persons-with-severe-visual-impairment
#1
Heller Madsen, Henrik Dam, Ida Hageman
BACKGROUND: Light plays a crucial role in both the pathogenesis and treatment of seasonal affective disorder (SAD). Consequently decreased retinal sensitivity to light has been suggested to be a risk factor for SAD. In a population of persons with severe visual impairment we recently found a highly increased prevalence of SAD. We now aimed to identify eye disorders or anatomical locations with specific association to seasonality. METHODS: In 912 cases (33%) from our prior seasonal pattern assessment questionnaire (SPAQ) screening study, we retrieved eye diagnoses from the Danish National Patient Registry and analyzed for specific eye disorders or anatomical locations that significantly differentiated SPAQ outcomes (global seasonality score, (GSS) and SPAQ-SAD prevalence)...
April 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28430521/perinatal-light-imprinting-of-circadian-clocks-and-systems-pliccs-a-signature-of-photoperiod-around-birth-on-circadian-system-stability-and-association-with-cancer
#2
Philip Lewis, Thomas C Erren
Recent findings from animal models suggest that plasticity of human circadian clocks and systems may be differentially affected by different paradigms of perinatal photoperiod exposure to the detriment of health in later life, including cancer development. Focusing on the example of cancer, we carry out a series of systematic literature reviews concerning perinatal light imprinting of circadian clocks and systems (PLICCS) in animal models, and concerning the risk of cancer development with the primary determinants of the perinatal photoperiod, namely season of birth or latitude of birth...
April 21, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28397148/the-correct-diagnosis-and-therapeutic-management-of-tear-dysfunction-recommendations-of-the-p-i-c-a-s-s-o-board
#3
REVIEW
Maurizio Rolando, Emilia Cantera, Rita Mencucci, Pierangela Rubino, Pasquale Aragona
PURPOSE: To describe a standard approach to manage tear dysfunction (TD), in order to obtain a clinically favourable outcome. TD is a highly prevalent, yet largely underdiagnosed, condition that affects from 5 to 30% of the population above 50 years old. Left untreated, TD is associated with eye discomfort and ocular surface disease, substantially affecting quality of life. Although the prevalence of this problem is increasing significantly, a standard approach to its prevention and treatment is not available yet...
April 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28364591/seasonal-affective-disorder-and-alcohol-abuse-disorder-in-a-population-based-study
#4
Isabel Morales-Muñoz, Seppo Koskinen, Timo Partonen
Seasonal affective disorder (SAD) is a recurrent major depressive disorder with a seasonal pattern, which is characterized by sad mood, low energy, longer sleep duration and carbohydrate craving. Furthermore, seasonal changes in mood and behavior may be closely related to alcohol use disorder (AUD). Nevertheless, there is scarce research on the study of cognitive impairments in SAD and AUD. We aimed to examine the relationship between the prevalence between SAD and AUD patients, and how cognitive functioning might be related to these variables...
March 18, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28345527/prevalence-and-factors-promoting-the-occurrence-of-vitamin-d-deficiency-in-the-elderly
#5
Magdalena Wyskida, Katarzyna Wieczorowska-Tobis, Jerzy Chudek
Vitamin D deficiency affects a large part of the population of elderly people, especially women, who live in moderate climate countries due to a reduced amount of vitamin D in the diet (small sea fish consumption) and reduced content of 7-dehydrocholesterol, which causes decreased skin synthesis. The lowest seasonal concentration of 25(OH)D3 is usually observed during winter and spring. Sun exposure influences 25(OH)D3 concentration more strongly in men than in women. Sociodemographic factors that increase the risk of vitamin D deficiency in the elderly include poor environmental conditions, low economic status, lower educational level, drug exposure (smoking), reduced physical activity, overall poor health and obesity, which causes reduced skin exposure to sunlight...
March 13, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28329660/predictors-of-tanning-dependence-in-white-non-hispanic-females-and-males
#6
Brenda Cartmel, Susan T Mayne, Allen E Bale, Joel Gelernter, Andrew DeWan, David J Leffell, Sherry Pagoto, Peter Spain, Leah M Ferrucci
Growing evidence suggests some individuals may exhibit dependence to ultraviolet light, a known carcinogen; however, few studies have investigated predictors of tanning dependence (TD).A sub-set of early-onset basal cell carcinoma case-control study participants completed an online survey. The modified-Cut down, Annoyed, Guilty, Eye-opener (mCAGE) and a questionnaire based on the addiction criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (mDSM-IV-TR) were used to classify participants having'Symptoms of TD' if they met criteria for TD on both questionnaires, 'Tendency for TD' if met criteria on only one questionnaire, or 'Not TD'...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28293623/patients-experience-of-winter-depression-and-light-room-treatment
#7
Cecilia Rastad, Lennart Wetterberg, Cathrin Martin
Background. There is a need for more knowledge on the effects of light room treatment in patients with seasonal affective disorder and to explore patients' subjective experience of the disease and the treatment. Methods. This was a descriptive and explorative study applying qualitative content analysis. A purposeful sample of 18 psychiatric outpatients with a major depressive disorder with a seasonal pattern and a pretreatment score ≥12 on the 9-item Montgomery-Åsberg Depression self-rating scale was included (10 women and 8 men, aged 24-65 years)...
2017: Psychiatry Journal
https://www.readbyqxmd.com/read/28262145/predictors-of-metabolic-syndrome-in-first-manic-episode
#8
Sermin Kesebir, Boray Erdinç, Nevzat Tarhan
OBJECTIVE: In the present study we aimed to investigate, whether an association between metabolic syndrome (MetS) and clinical features and affective temperaments exists or not in first manic episode of bipolar disorder (BD) and to clarify the prevalence and predictors of MetS. METHOD: A total of 150 patients who were received a diagnosis of bipolar disorder type I according to DSM-IV criteria and who were experiencing their first manic episode (FME) were screened consecutively for inclusion...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28256616/dose-and-time-effect-responses-of-dna-methylation-and-histone-h3k9-acetylation-changes-induced-by-traffic-related-air-pollution
#9
Rui Ding, Yongtang Jin, Xinneng Liu, Huaizhuang Ye, Ziyi Zhu, Yuan Zhang, Ting Wang, Yinchun Xu
As an important risk factor of respiratory disorders, traffic-related air pollution (TRAP) has caused extensive concerns. Epigenetic change has been considered a link between TRAP and respiratory diseases. However, the exact effects of TRAP on epigenetic changes are still unclear. Here we investigated the dose- and time- effect responses of TRAP on DNA methylations and H3K9 acetylation (H3K9ac) in both blood and lung tissues of rats. The findings showed that every 1 μg/m(3) increase of TRAP components were associated with changes in %5 mC (95% CI) in LINE-1, iNOS, p16(CDKN2A), and APC ranging from -0...
March 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28251921/clinical-implications-of-the-melanopsin-based-non-image-forming-visual-system
#10
REVIEW
Alexander Ksendzovsky, I Jonathan Pomeraniec, Kareem A Zaghloul, J Javier Provencio, Ignacio Provencio
Since the discovery of the non-image-forming visual system, tremendous research efforts have been dedicated to understanding its mechanisms and functional roles. Original functions associated with the melanopsin system include the photoentrainment of circadian sleep-wake cycles and the pupillary light reflex. Recent findings, however, suggest a much broader involvement of this system in an array of physiologic responses to light. This newfound insight into the underlying function of the non-image-forming system has revealed the many connections to human pathology and attendant disease states, including seasonal affective disorder, migraine, glaucoma, inherited mitochondrial optic neuropathy, and sleep dysregulation of aging...
March 28, 2017: Neurology
https://www.readbyqxmd.com/read/28182445/state-dependent-alterations-in-inhibitory-control-and-emotional-face-identification-in-seasonal-affective-disorder
#11
Liv V Hjordt, Dea S Stenbæk, Kathrine Skak Madsen, Brenda Mc Mahon, Christian G Jensen, Martin Vestergaard, Ida Hageman, David Meder, Steen G Hasselbalch, Gitte M Knudsen
BACKGROUND: Depressed individuals often exhibit impaired inhibition to negative input and identification of positive stimuli, but it is unclear whether this is a state or trait feature. We here exploited a naturalistic model, namely individuals with seasonal affective disorder (SAD), to study this feature longitudinally. AIM: The goal of this study was to examine seasonal changes in inhibitory control and identification of emotional faces in individuals with SAD...
April 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28135573/retinal-venous-blood-carbon-monoxide-response-to-bright-light-in-male-pigs-a-preliminary-study
#12
Dan A Oren, Magdalena Duda, Katarzyna Kozioł, Maria Romerowicz-Misielak, Anna Koziorowska, Przemysław Sołek, Sławomir Nowak, Magdalena Kulpa, Marek Koziorowski
The physical mechanism by which light is absorbed in the eye and has antidepressant and energizing effects in Seasonal Affective Disorder and other forms of psychiatric major depression is of scientific interest. This study was designed to explore one specific aspect of a proposed humoral phototransduction mechanism, namely that carbon monoxide (CO) levels increase in retinal venous blood in response to bright light. Eleven mature male pigs approximately six months of age were kept for 7days in darkness and fasted for 12h prior to surgery...
March 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28129487/predictors-of-tanning-dependence-in-white-non-hispanic-females-and-males
#13
B Cartmel, A E Bale, S T Mayne, J E Gelernter, A T DeWan, P Spain, D J Leffell, S Pagoto, L M Ferrucci
BACKGROUND: Growing evidence suggests that some individuals may exhibit symptoms of dependence on ultraviolet (UV) light, a known carcinogen, in the context of tanning; however, few studies have investigated predictors of tanning dependence (TD). OBJECTIVE: To identify predictors of TD. METHODS: Non-Hispanics of European ancestry who had previously participated in a case-control study of early-onset basal cell carcinoma completed an online survey to ascertain TD and other behaviours (alcohol dependence, nicotine dependence, seasonal affective disorder (SAD), exercise 'addiction' and depression)...
January 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28117197/effect-of-social-deprivation-on-the-admission-rate-and-outcomes-of-adult-respiratory-emergency-admissions
#14
Seán Cournane, Declan Byrne, Richard Conway, Deirdre O'Riordan, Seamus Coveney, Bernard Silke
BACKGROUND: Patients with respiratory disorders constitute a major source of activity for Acute Medicine. We have examined the impact of Socio-Economic Status (SES) and weather factors on the outcomes (30-day in-hospital mortality) of emergency hospitalisations with a respiratory presentation. METHODS: All emergency respiratory admissions to St. James Hospital, Dublin, from 2002 to 2014 were evaluated. Patients were categorized by quintile of Deprivation Index, and evaluated against hospital admission rate (/1000 population) and 30-day in-hospital mortality...
January 17, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28075103/extended-release-bupropion-for-preventing-seasonal-affective-disorder-in-adults
#15
Megan K Magovern, Amy Crawford-Faucher
No abstract text is available yet for this article.
January 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28012610/secondary-to-excessive-melatonin-synthesis-the-consumption-of-tryptophan-from-outside-the-blood-brain-barrier-and-melatonin-over-signaling-in-the-pars-tuberalis-may-be-central-to-the-pathophysiology-of-winter-depression
#16
José Carlos Pereira, Márcia Pradella Hallinan, Rosana Cardoso Alves
Seasonal affective disorder is defined as recurrent episodes of major depression, mania, or hypomania with seasonal onset and remission. In this class of mood disturbances, a unipolar major depressive disorder known as winter depression is common in populations living in northern latitudes far from the equator. Winter depression repeatedly occurs in the autumn or winter and remits in the spring or summer, and its etiopathogenesis is currently unknown. However, one can surmise that excessive melatonin production during the reduced duration of daily sunlight in the autumn and winter plays a role in its pathophysiology...
January 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/27979316/seasonal-mood-changes-in-patients-with-obsessive-compulsive-disorder
#17
Oğuz Tan, Barış Metin, Barış Önen Ünsalver, Gökben Hızlı Sayar
Obsessive-compulsive disorder (OCD) is frequently associated with mood disorders. However, to date, the co-occurrence of OCD with seasonal affective disorder (SAD) has not been investigated. We have aimed to estimate the prevalence of seasonal mood changes in patients with OCD and explore the contribution of seasonality in mood to the severity of OCD. The Seasonal Pattern Assessment Questionnaire (SPAQ), the Yale-Brown Obsession and Compulsion Scale (Y-BOCS), the Hamilton Depression Rating Scale-17 Items (HDRS-17), and the Beck Anxiety Inventory (BAI) were administered to patients with OCD (n=104) and controls (n=125)...
June 16, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27975357/-light-and-medicine
#18
REVIEW
Björn Lemmer
There would be no life without light. The rotation of the earth around its axis has introduced the development of biological clocks in all living subjects regulating all functions of the body. The rhythms best described are the 24-hour/circadian and the seasonal rhythms. The rhythmic composition around the body clock has great impact on health and disease, both in diagnostics and treatment. Nowadays, bright light, e.g. in seasonal affective disorder, can be regarded as a drug, being even more effective than selective serotonin reuptake inhibitors...
December 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27956776/prevalence-of-ketosis-in-dairy-cows-in-milk-shed-areas-of-odisha-state-india
#19
Sangram Biswal, Dhruba Charan Nayak, Kautuk Kumar Sardar
AIM: The present study was conducted to ascertain the prevalence of ketosis in dairy cows in dairy herds, milksheds, and mixed population of milk cows selected randomly in milkshed areas of Odisha state, India. MATERIALS AND METHODS: The investigation was conducted in 280 private dairy herds with variable herd size of 10-15 cows comprising crossbred Jersey cows (CBJ), crossbred Holstein Friesian (CHF) cows, and indigenous local breeds. The analysis of urine (Rothera's test), milk (Ross test), and blood samples of 2760 test cows were conducted through qualitative assessment by Rothera's test and Ross test, respectively, for the presence of ketone bodies to screen the ketotic animals...
November 2016: Veterinary World
https://www.readbyqxmd.com/read/27942348/estimated-economic-benefit-of-increasing-25-hydroxyvitamin-d-concentrations-of-canadians-to-or-above-100%C3%A2-nmol-l
#20
REVIEW
William B Grant, Susan J Whiting, Gerry K Schwalfenberg, Stephen J Genuis, Samantha M Kimball
Mounting evidence from observational and clinical trials indicates that optimal vitamin D reduces the risk of many diseases. We used observational studies and recent data on 25-hydroxyvitamin D [25(OH)D] concentrations of Canadians from Cycle 3 of the Canadian Health Measures Survey to estimate the reduction in disease incidence, mortality rates, and the total economic burden (direct plus indirect) of disease if 25(OH)D concentrations of all Canadians were raised to or above 100 nmol/L. Recently, the mean 25(OH)D concentration of Canadians varied depending on age and season (51-69 nmol/L), with an overall mean of 61 nmol/L...
January 2016: Dermato-endocrinology
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