Martin Scharffenberg, Maura Mandelli, Thomas Bluth, Francesca Simonassi, Jakob Wittenstein, Robert Teichmann, Katharina Birr, Thomas Kiss, Lorenzo Ball, Paolo Pelosi, Marcus J Schultz, Marcelo Gama de Abreu, Robert Huhle
STUDY OBJECTIVE: We aimed to characterize intra-operative mechanical ventilation with low or high positive end-expiratory pressure (PEEP) and recruitment manoeuvres (RM) regarding intra-tidal recruitment/derecruitment and overdistension using non-linear respiratory mechanics, and mechanical power in obese surgical patients enrolled in the PROBESE trial. DESIGN: Prospective, two-centre substudy of the international, multicentre, two-arm, randomized-controlled PROBESE trial...
February 2024: Journal of Clinical Anesthesia