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https://www.readbyqxmd.com/read/28430867/emerging-evidence-for-the-role-of-differential-tumor-microenvironment-in-breast-cancer-racial-disparity-a-closer-look-at-the-surroundings
#1
Sachin Kumar Deshmukh, Sanjeev K Srivastava, Nikhil Tyagi, Aamir Ahmad, Ajay P Singh, Ahmed Al Ghadhban, Donna L Dyess, James E Carter, Kari Dugger, Seema Singh
Although increased awareness leading to early detection and prevention, as well as advancements in treatment strategies, have resulted in superior clinical outcomes, African American women with breast cancer continue to have greater mortality rates, compared to Caucasian American counterparts. Moreover, African American women are more likely to have breast cancer at a younger age and be diagnosed with aggressive tumor sub-types. Such racial disparities can be attributed to socioeconomic differences, but it is increasingly being recognized that these disparities may indeed be due to certain genetic and other non-genetic biological differences...
April 18, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/28429791/social-and-anthropometric-factors-explaining-racial-ethnical-differences-in-birth-weight-in-the-united-states
#2
Naho Morisaki, Ichiro Kawachi, Emily Oken, Takeo Fujiwara
Though disparities in birth weight by race/ethnicity have been extensively reported in the United States, few studies have systematically investigated factors attributing to its variability. For 10,638,415 singleton infants born during 2009-2012 in the United States, we examined birth weight differences among 14 races and ethnicities (non-Hispanic white, non-Hispanic Black, American Indian, Asian Indian, Chinese, Filipino, Japanese, Korean, Vietnamese, Hawaiian, Guamanian, Mexican, Puerto Rican and Cuban), after sequentially adjusting for maternal, socio-economic and behavioral factors...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28428893/characteristics-and-racial-variations-of-polypoidal-choroidal-vasculopathy-in-tertiary-centers-in-the-united-states-and-united-kingdom
#3
Tarek Alasil, Nelida Munoz, Pearse A Keane, Adnan Tufail, Patrick A Coady, Eduardo Novais, Talisa E de Carlo, Caroline R Baumal, Nadia K Waheed, Jay S Duker, Ron A Adelman
PURPOSE: To evaluate the characteristics and racial variations amongst patients with polypoidal choroidal vasculopathy (PCV) in the United States and the United Kingdom. METHODS: Fundus photos and indocyanine green angiography images were evaluated in a multicenter retrospective study to establish the diagnosis of PCV. Visual acuity (VA) was recorded in ETDRS letter count. RESULTS: Eighty eyes of 71 PCV patients (average age of 69.4 ± 10...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28427954/colorectal-cancer-screening-initiation-after-age-50-years-in-an-organized-program
#4
Stacey A Fedewa, Douglas A Corley, Christopher D Jensen, Wei Zhao, Michael Goodman, Ahmedin Jemal, Kevin C Ward, Theodore R Levin, Chyke A Doubeni
INTRODUCTION: Recent studies report racial disparities among individuals in organized colorectal cancer (CRC) programs; however, there is a paucity of information on CRC screening utilization by race/ethnicity among newly age-eligible adults in such programs. METHODS: This was a retrospective cohort study among Kaiser Permanente Northern California enrollees who turned age 50 years between 2007 and 2012 (N=138,799) and were served by a systemwide outreach and facilitated in-reach screening program based primarily on mailed fecal immunochemical tests to screening-eligible people...
April 17, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28427484/racial-and-ethnic-subgroup-disparities-in-hypertension-prevalence-new-york-city-health-and-nutrition-examination-survey-2013-2014
#5
Kezhen Fei, Jesica S Rodriguez-Lopez, Marcel Ramos, Nadia Islam, Chau Trinh-Shevrin, Stella S Yi, Claudia Chernov, Sharon E Perlman, Lorna E Thorpe
INTRODUCTION: Racial/ethnic minority adults have higher rates of hypertension than non-Hispanic white adults. We examined the prevalence of hypertension among Hispanic and Asian subgroups in New York City. METHODS: Data from the 2013-2014 New York City Health and Nutrition Examination Survey were used to assess hypertension prevalence among adults (aged ≥20) in New York City (n = 1,476). Hypertension was measured (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg or self-reported hypertension and use of blood pressure medication)...
April 20, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28426620/committee-opinion-no-699-adolescent-pregnancy-contraception-and-sexual-activity
#6
(no author information available yet)
In 2015, the birth rate among U.S. adolescents and young adults (aged 15-19 years) reached a historic low at 22.3 per 1,000 women. Despite positive trends, the United States continues to have the highest adolescent pregnancy rate among industrialized countries with data. Racial and ethnic disparities in adolescent pregnancy rates continue to exist, as do state-based differences in pregnancy, birth, and abortion rates. The American College of Obstetricians and Gynecologists supports access for adolescents to all contraceptive methods approved by the U...
May 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28426615/committee-opinion-no-699-adolescent-pregnancy-contraception-and-sexual-activity
#7
(no author information available yet)
In 2015, the birth rate among U.S. adolescents and young adults (aged 15-19 years) reached a historic low at 22.3 per 1,000 women. Despite positive trends, the United States continues to have the highest adolescent pregnancy rate among industrialized countries with data. Racial and ethnic disparities in adolescent pregnancy rates continue to exist, as do state-based differences in pregnancy, birth, and abortion rates. The American College of Obstetricians and Gynecologists supports access for adolescents to all contraceptive methods approved by the U...
May 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28426457/race-differences-in-initial-presentation-early-treatment-and-1-year-outcomes-of-pediatric-crohn-s-disease-results-from-the-improvecarenow-network
#8
Jennifer L Dotson, Michele Cho, Josh Bricker, Michael D Kappelman, Deena J Chisolm, Gitit Tomer, Wallace V Crandall
BACKGROUND: Racially disparate care has been shown to contribute to suboptimal health care outcomes for minorities. Using the ImproveCareNow network, we investigated differences in management and outcomes of pediatric patients with Crohn's disease at diagnosis and 1-year postdiagnosis. METHODS: ImproveCareNow is a learning health network for pediatric inflammatory bowel disease. It contains prospective, longitudinal data from outpatient encounters. This retrospective study included all patients with Crohn's disease ≤21 years, September 2006 to October 2014, with the first recorded encounter ≤90 days from date of diagnosis and an encounter 1 year ±60 days...
May 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28425473/2d-dige-as-a-strategy-to-identify-serum-biomarkers-in-mexican-patients-with-type-2-diabetes-with-different-body-mass-index
#9
Erik E Gómez-Cardona, Eric E Hernández-Domínguez, Aída J Velarde-Salcedo, Alberto-Barrera- Pacheco, Agustín Diaz-Gois, Antonio De León-Rodríguez, Ana P Barba de la Rosa
Obesity and type 2 diabetes(T2D) are the most prevalent and serious metabolic diseases affecting people worldwide. However racial and ethnic disparities seems to be a risk factor for their development. Mexico has been named as one of the largest populations with the highest prevalence of diabetes and obesity. The aim of this study was to identify novel T2D-associated proteins in Mexican patients. Blood samples were collected from 62 Mexican patients with T2D and they were grouped according to their body mass index(BMI)...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28424651/racial-assumptions-color-the-mental-representation-of-social-class
#10
Ryan F Lei, Galen V Bodenhausen
We investigated the racial content of perceivers' mental images of different socioeconomic categories. We selected participants who were either high or low in prejudice toward the poor. These participants saw 400 pairs of visually noisy face images. Depending on condition, participants chose the face that looked like a poor person, a middle income person, or a rich person. We averaged the faces selected to create composite images of each social class. A second group of participants rated the stereotypical Blackness of these images...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28424184/demographic-lifestyle-and-genetic-determinants-of-circulating-concentrations-of-25-hydroxyvitamin-d-and-vitamin-d-binding-protein-in-african-american-and-european-american-women
#11
Song Yao, Chi-Chen Hong, Elisa V Bandera, Qianqian Zhu, Song Liu, Ting-Yuan David Cheng, Gary Zirpoli, Stephen A Haddad, Kathryn L Lunetta, Edward A Ruiz-Narvaez, Susan E McCann, Melissa A Troester, Lynn Rosenberg, Julie R Palmer, Andrew F Olshan, Christine B Ambrosone
Background: Vitamin D may have anticancer activities. The high prevalence of vitamin D deficiency in African Americans (AAs) may be a contributing factor to the cancer health disparities between AAs and European Americans (EAs).Objectives: We compared concentrations of 25(OH)D and vitamin D-binding protein (VDBP) in AA and EA women and investigated determinants of the vitamin D-biomarker concentrations in both populations.Design: We used data and biospecimens from 909 AA and 847 EA healthy control subjects from the Carolina Breast Cancer Study (CBCS) and the Women's Circle of Health Study (WCHS) in the African American Breast Cancer Epidemiology and Risk Consortium...
April 19, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28423991/changes-in-body-mass-stature-and-bmi-in-south-african-elite-u18-rugby-players-from-different-racial-groups-from-2002-2012
#12
Justin Durandt, Mervin Green, Herman Masimla, Mike Lambert
The purpose of this study was to determine whether there are differences between racial groups for body mass, stature and body mass index (BMI) in South African elite U18 rugby players and whether there were significant changes in these measurements between 2002 and 2012. Self-reported body mass and stature were obtained from U18 players (n = 4007) who attended the national tournament during this period. BMI was calculated for each player.White players were 9.8 kg heavier than black players, who were 2.3 kg heavier than coloured players (P < 0...
April 20, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28423153/heterogeneity-in-blood-pressure-transitions-over-the-life-course-age-specific-emergence-of-racial-ethnic-and-sex-disparities-in-the-united-states
#13
Shakia T Hardy, Katelyn M Holliday, Sujatro Chakladar, Joseph C Engeda, Norrina B Allen, Gerardo Heiss, Donald M Lloyd-Jones, Pamela J Schreiner, Christina M Shay, Danyu Lin, Donglin Zeng, Christy L Avery
Importance: Many studies have assessed racial/ethnic and sex disparities in the prevalence of elevated blood pressure (BP) from childhood to adulthood, yet few have examined differences in age-specific transitions between categories of BP over the life course in contemporary, multiracial/multiethnic populations. Objective: To estimate age, racial/ethnic, and sex-specific annual net transition probabilities between categories of BP using Markov modeling of cross-sectional data from the National Health and Nutrition Examination Survey...
April 19, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28423134/infant-mortality-by-color-or-race-from-rond%C3%A3-nia-brazilian-amazon
#14
Caroline Gava, Andrey Moreira Cardoso, Paulo Cesar Basta
OBJECTIVE: To analyze the quality of records for live births and infant deaths and to estimate the infant mortality rate for skin color or race, in order to explore possible racial inequalities in health. METHODS: Descriptive study that analyzed the quality of records of the Live Births Information System and Mortality Information System in Rondônia, Brazilian Amazonian, between 2006-2009. The infant mortality rates were estimated for skin color or race with the direct method and corrected by: (1) proportional distribution of deaths with missing data related to skin color or race; and (2) application of correction factors...
April 10, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28422849/temporal-trends-in-centralization-and-racial-disparities-in-utilization-of-high-volume-hospitals-for-lung-cancer-surgery
#15
Wil Lieberman-Cribbin, Bian Liu, Emanuele Leoncini, Raja Flores, Emanuela Taioli
Racial disparities have been suggested in hospital utilization and outcome for lung cancer surgery, but the effect of hospital centralization on closing this gap is unknown. We hypothesized that centralization has increased the utilization of high- or very-high-volume (HV/VHV) hospitals, a proxy for access to high-quality care, over the study period independently from race.Inpatient records were extracted from the New York Statewide Planning and Research Cooperative System database (1995-2012) according to Clinical Modification of the International Classification of Diseases, 9th Revision diagnosis codes 162...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28422803/marijuana-use-and-self-reported-quality-of-eyesight
#16
Obinna F Akano
PURPOSE: There is increasing use of marijuana among young adults and more states in the United States are legalizing medical marijuana use. A number of studies have revealed both the beneficial and harmful effects of marijuana to the human system. Despite some beneficial effects, studies have shown marijuana to have a lot of deleterious effects on the visual system, which subsequently reduces the quality of eyesight. The aim of this study was to investigate if heavy marijuana smoking is associated with a poor quality of eyesight compared with light/no use of marijuana...
April 18, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28418750/comparing-asian-american-women-s-knowledge-self-efficacy-and-perceived-risk-of-heart-attack-to-other-racial-and-ethnic-groups-the-mped-trial
#17
Yoshimi Fukuoka, Nadra E Lisha, Eric Vittinghoff
OBJECTIVE: The aim of the study was to compare knowledge and awareness of heart attacks/heart disease and perceived risk for future heart attack in Asian/Pacific Islander women, compared to other racial and ethnic groups. MATERIALS AND METHODS: In this cross-sectional study, 318 women enrolled in a mobile phone-based physical activity education trial were analyzed. Heart attack knowledge, self-efficacy for recognizing and responding to heart attack symptoms, and perceived risk for a future heart attack were measured...
April 18, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28417334/sleep-quality-duration-and-breast-cancer-aggressiveness
#18
Allison Soucise, Caila Vaughn, Cheryl L Thompson, Amy E Millen, Jo L Freudenheim, Jean Wactawski-Wende, Amanda I Phipps, Lauren Hale, Lihong Qi, Heather M Ochs-Balcom
PURPOSE: Epidemiological studies suggest that short sleep duration and poor sleep quality may increase breast cancer risk. However, whether sleep is associated with breast tumor aggressiveness characteristics has largely been unexplored. METHODS: The study included 4171 non-Hispanic whites (NHW) and 235 African Americans (AA) diagnosed with incident, primary, invasive breast cancer in the Women's Health Initiative (WHI) Observational Study (1994-2013). We used logistic regression to examine the association of baseline sleep (sleep duration, sleep quality, WHI Insomnia Rating Scale) with tumor grade, stage, hormone receptor status, HER2 status...
April 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28415994/a-pathological-and-clinical-study-of-706-primary-tumours-of-the-ovary-in-the-largest-tertiary-hospital-in-ghana
#19
Patrick Kafui Akakpo, Leonard Derkyi-Kwarteng, Richard Kwasi Gyasi, Solomom Edward Quayson, Simon Naporo, Jehoram Tei Anim
BACKGROUND: Ovarian tumours are a leading cause of death in Ghana. Even though geographical and racial differences exist in the frequency, types and age distribution of primary ovarian tumours, information about the clinical and pathological characteristics of ovarian tumours in Ghana and its neighboring countries is scanty. We determined the frequency, age distribution, histopathological types and clinical features of primary ovarian tumours diagnosed at the Korle-Bu Teaching Hospital in Ghana to aid in the management of patients...
April 17, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28414260/retention-in-hiv-care-and-viral-suppression-individual-and-neighborhood-level-predictors-of-racial-ethnic-differences-florida-2015
#20
Diana M Sheehan, Kristopher P Fennie, Daniel E Mauck, Lorene M Maddox, Spencer Lieb, Mary Jo Trepka
The objective of this study was to estimate racial/ethnic differences in retention in HIV care and viral suppression and to identify related individual and neighborhood determinants. Florida HIV surveillance records of cases aged ≥13 years diagnosed during the years 2000-2014 were analyzed. Retention in care was defined as evidence of ≥2 or more laboratory tests, receipts of prescription, or clinical visits at least 3 months apart during 2015. Viral load suppression was defined as a viral load of <200 copies/mL for the last test in 2015...
April 2017: AIDS Patient Care and STDs
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