Undine A Gerlach, Georgios Vrakas, Srikanth Reddy, Daniel C Baumgart, Daniel C Baumgar, Peter Neuhaus, Peter J Friend, Andreas Pascher, Anil Vaidya
IMPORTANCE: Because of the severity of disease and additional surgery, Crohn disease (CD) may result in intestinal failure (IF) and dependency on home parenteral nutrition (HPN). Defining the indication and timing for intestinal transplantation (ITx) is challenging. OBJECTIVES: To determine the limitations of conventional surgery and to facilitate the decision making for transplantation. DESIGN, SETTING, AND PARTICIPANTS: Data were collected prospectively and obtained by retrospective review of medical records from all patients with CD who were assessed for ITx in Oxford, United Kingdom, and Berlin, Germany, from October 10, 2003, through July 31, 2013...
October 2014: JAMA Surgery