keyword
https://read.qxmd.com/read/38604668/impact-of-large-scale-multicomponent-intervention-to-reduce-proton-pump-inhibitor-overuse-in-integrated-healthcare-system-difference-in-difference-study
#21
JOURNAL ARTICLE
Jacob E Kurlander, Loren Laine, Hyungjin Myra Kim, Christopher B Roberts, Darcy Saffar, Aimee Myers, Robert Holleman, Yuqing Gao, Michelle Shank, Richard Nelson, Jane Forman, Christian D Helfrich, Sarah L Krein, Sameer D Saini, Yu-Xiao Yang
OBJECTIVE: To determine how a large scale, multicomponent, pharmacy based intervention to reduce proton pump inhibitor (PPI) overuse affected prescribing patterns, healthcare utilization, and clinical outcomes. DESIGN: Difference-in-difference study. SETTING: US Veterans Affairs Healthcare System, in which one regional network implemented the overuse intervention and all 17 others served as controls. PARTICIPANTS: All individuals receiving primary care from 2009 to 2019...
April 11, 2024: BMJ: British Medical Journal
https://read.qxmd.com/read/38603539/institutional-practices-for-charitable-medication-access-for-uninsured-patients
#22
JOURNAL ARTICLE
Akshara Kumar, Caitlin Dowd-Green, Robert Green, Rosalyn Stewart
OBJECTIVES: To identify the most frequently prescribed medications, the location where prescriptions were filled, and whether a voucher was utilized among patients enrolled in a charitable care program within an academic medical center. STUDY DESIGN: This was a retrospective cohort study analyzing electronic health record and pharmacy dispensing information at a medical center's outpatient pharmacies. METHODS: Patients included in this analysis were enrolled in a charitable care program and had at least 1 ambulatory encounter in a primary care clinic from March 1, 2019, to June 30, 2021...
April 1, 2024: American Journal of Managed Care
https://read.qxmd.com/read/38601976/cost-consequence-analysis-of-adding-semaglutide-to-treatment-regimen-for-patients-with-type-ii-diabetes-in-saudi-arabia
#23
JOURNAL ARTICLE
Yazed AlRuthia, Khaled Hani Aburisheh, Sondus Ata, Raghad Bin Salleeh, Shahad B Alqudhibi, Raghad B Alqudhibi, Ziad Alkraidis, Hala Humood Alkhalaf, Abdulrahman Abdullah Almogirah, Muhammad Mujammami, Reem Al Khalifah
INTRODUCTION: Semaglutide, a Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA), is often prescribed for managing type 2 diabetes, particularly in cases unresponsive to other hypoglycemic agents. Despite its popularity, the real-world efficacy and cost-effectiveness of Semaglutide relative to other treatments remain understudied. OBJECTIVE: This study aimed to examine the direct medical cost and consequences of adding Semaglutide to the treatment regimen for patients with type 2 diabetes in Saudi Arabia...
May 2024: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://read.qxmd.com/read/38601187/exploring-the-use-usefulness-and-ease-of-use-of-digital-occupational-health-services-a-descriptive-correlational-study-of-customer-experiences
#24
JOURNAL ARTICLE
Sari Nissinen, Sanna Pesonen, Pauliina Toivio, Erja Sormunen
OBJECTIVE: This study examined the customer experiences of use, perceived usefulness and ease of use of digital occupational health (OH) services. METHODS: A cross-sectional study based on an electronic survey was conducted between December 2022 and January 2023. A total of 9871 OH customers responded to the survey. The sample was restricted to respondents who used digital OH services (n = 7275). An analysis of variance was run to test the relationships between respondents' characteristics and the rate of usefulness, and ease of use variables...
2024: Digital Health
https://read.qxmd.com/read/38600951/age-stratified-comorbid-and-pharmacologic-analysis-of-patients-with-glioblastoma
#25
JOURNAL ARTICLE
Erik E Rabin, Jonathan Huang, Miri Kim, Andreas Mozny, Kristen L Lauing, Manon Penco-Campillo, Lijie Zhai, Prashant Bommi, Xinlei Mi, Erica A Power, Vikram C Prabhu, Douglas E Anderson, Kevin P Barton, Theresa L Walunas, Gary E Schiltz, Christina Amidei, Pilar Sanchez-Gomez, Jigisha P Thakkar, Rimas V Lukas, Derek A Wainwright
BACKGROUND: Increased age is a strong and unfavorable prognostic factor for patients with glioblastoma (GBM). However, the relationships between stratified patient age, comorbidities, and medications have yet to be explored in GBM patient survival analyses. OBJECTIVE: To evaluate co-morbid conditions, tumor-related symptoms, medication prescriptions, and subject age for patients with GBM and to establish potential targets for prospective studies. METHODS: Electronic health records for 565 patients with IDHwt GBM were evaluated at a single center between January 1, 2000 and August 9, 2021 were retrospectively assessed...
July 2024: Brain, behavior, & immunity health
https://read.qxmd.com/read/38600534/implementation-and-evaluation-of-an-interprofessional-prescription-writing-workshop-with-a-simulated-electronic-prescribing-activity-for-preclerkship-medical-students
#26
JOURNAL ARTICLE
Christopher Guyer, Brittany Stewart, Ziad Khalifa, Linh Pham, Aline H Saad
BACKGROUND: Prescription writing skills are essential for physician practice. This study describes the development and implementation of a curricular intervention focused on improving the knowledge and confidence of preclerkship medical students' prescription writing practices utilizing an interprofessional education model, with a focus on electronic prescribing. METHODS: Medicine and Pharmacy Faculty from a large, urban university collaborated to develop the content of the workshop and a simulation platform was used for the e-prescribing activity...
April 10, 2024: BMC Medical Education
https://read.qxmd.com/read/38600444/potentially-inappropriate-prescribing-for-people-with-dementia-in-ambulatory-care-a-cross-sectional-observational-study
#27
JOURNAL ARTICLE
Nahla A Alageel, Carmel M Hughes, Monira Alwhaibi, Walid Alkeridy, Heather E Barry
BACKGROUND: Studies have shown that potentially inappropriate prescribing (PIP) is highly prevalent among people with dementia (PwD) and linked to negative outcomes, such as hospitalisation and mortality. However, there are limited data on prescribing appropriateness for PwD in Saudi Arabia. Therefore, we aimed to estimate the prevalence of PIP and investigate associations between PIP and other patient characteristics among PwD in an ambulatory care setting. METHODS: A cross-sectional, retrospective analysis was conducted at a tertiary hospital in Saudi Arabia...
April 10, 2024: BMC Geriatrics
https://read.qxmd.com/read/38599788/pharmacist-only-supply-of-nicotine-vaping-products-proposing-an-alternative-regulatory-model-for-australia
#28
EDITORIAL
Samuel Brookfield, Kathryn J Steadman, Lisa Nissen, Coral E Gartner
Regulation of nicotine vaping products (NVPs) is an ongoing challenge across the world. Australia currently has a globally unique NVP regulatory model that requires a medical prescription to purchase and use NVPs, with further restrictions in progress in response to evidence of widespread illicit NVP sales. Against this background, we examine the new measures and consider a modification of the model to pharmacist-only supply as an option for increasing access to NVPs for smoking cessation, while retaining health practitioner oversight of supply...
April 10, 2024: Tobacco Control
https://read.qxmd.com/read/38596848/scalable-approach-to-consumer-wearable-postmarket-surveillance-development-and-validation-study
#29
JOURNAL ARTICLE
Richard M Yoo, Ben T Viggiano, Krishna N Pundi, Jason A Fries, Aydin Zahedivash, Tanya Podchiyska, Natasha Din, Nigam H Shah
BACKGROUND: With the capability to render prediagnoses, consumer wearables have the potential to affect subsequent diagnoses and the level of care in the health care delivery setting. Despite this, postmarket surveillance of consumer wearables has been hindered by the lack of codified terms in electronic health records (EHRs) to capture wearable use. OBJECTIVE: We sought to develop a weak supervision-based approach to demonstrate the feasibility and efficacy of EHR-based postmarket surveillance on consumer wearables that render atrial fibrillation (AF) prediagnoses...
April 4, 2024: JMIR Medical Informatics
https://read.qxmd.com/read/38593962/the-scutellaria-coptis-herb-couple-and-its-active-small-molecule-ingredient-wogonoside-alleviate-cytokine-storm-by-regulating-the-cd39-nlrp3-gsdmd-signaling-pathway
#30
JOURNAL ARTICLE
Huan Wang, Yuejia Lan, Liuling Luo, Yang Xiao, Xianli Meng, Yong Zeng, Jiasi Wu
ETHNOPHARMACOLOGICAL RELEVANCE: A drug pair is a fundamental aspect of traditional Chinese medicine prescriptions. Scutellaria baicalensis Georgi and Coptis chinensis Franch, commonly used as an herb couple (SBCC), are representative heat-clearing and dampness-drying drugs. They possess functions such as clearing heat, drying dampness, purging fire, and detoxifying. These herbs are used in both traditional and modern medicine for treating inflammation. AIM OF THE STUDY: This study investigated the effects of SBCC on cytokine storm syndrome (CSS) and explored its potential regulatory mechanism...
April 7, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38590811/does-nature-based-social-prescription-improve-mental-health-outcomes-a-systematic-review-and-meta-analysis
#31
Rashid Menhas, Lili Yang, Zulkaif Ahmed Saqib, Muhammad Younas, Muhammad Muddasar Saeed
BACKGROUND: A nature-based social prescription (NBSP) is an approach to improving mental health outcomes that involves prescribing nature-based interventions as complementary or alternative therapy to traditional ones. A variety of advantages are available from NBSP for people looking to enhance their mental well-being. The effect size of the nature-based social prescriptions (NBSPs) has not been thoroughly evaluated by systematic reviews and meta-analyses. OBJECTIVES: The current study aimed to analyze existing studies and conduct a meta-analysis to determine the overall effect size of the nature-based social prescriptions (NBSP's) outcomes on mental health...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38590457/content-and-duration-of-doctor-patient-communication-in-outpatient-oncology-follow-up-consultations-in-china
#32
JOURNAL ARTICLE
Yinxia Zhan, Peiyang Mao, Feng Gao, Qiuling Shi
Purpose This study aimed to analyze the content of counseling between cancer patients and physicians during outpatient follow-up, assess the duration of different communication content, and explore the influencing factors. Patients and methods We observed consecutive cancer patients without a first diagnosis of malignancy who presented to the oncology outpatient clinic of a public hospital from October through December 2023. A structured observation form was used to record the content and duration of doctor-patient communication...
March 2024: Curēus
https://read.qxmd.com/read/38589644/a-population-based-cohort-of-drug-exposures-and-adverse-pregnancy-outcomes-in-china-deep-rationale-design-and-baseline-characteristics
#33
JOURNAL ARTICLE
Jing Tan, Yiquan Xiong, Chunrong Liu, Peng Zhao, Pei Gao, Guowei Li, Jin Guo, Mingxi Li, Wanqiang Wei, Guanhua Yao, Yongyao Qian, Lishan Ye, Huanyang Qi, Hui Liu, Moliang Chen, Kang Zou, Lehana Thabane, Xin Sun
The DEEP cohort is the first population-based cohort of pregnant population in China that longitudinally documented drug uses throughout the pregnancy life course and adverse pregnancy outcomes. The main goal of the study aims to monitor and evaluate the safety of drug use through the pregnancy life course in the Chinese setting. The DEEP cohort is developed primarily based on the population-based data platforms in Xiamen, a municipal city of 5 million population in southeast China. Based on these data platforms, we developed a pregnancy database that documented health care services and outcomes in the maternal and other departments...
April 9, 2024: European Journal of Epidemiology
https://read.qxmd.com/read/38587170/impact-of-remote-medical-devices-on-utilization-of-medical-services-in-pediatric-patients-with-upper-respiratory-infections-a-retrospective-study
#34
JOURNAL ARTICLE
Inbal Mozes, Orna Baron-Epel, Anthony Heymann
Background: Remote mobile examination devices in telemedicine are a new technology in healthcare. Objective: To assess the utilization of visits using remote medical devices. Methods: A retrospective analysis of follow-up visits, referrals, laboratory testing and antibiotic prescriptions of 470,845 children's video visits with and without remote medical examination device and in-clinic visits. Results: Rates of follow-up visits, referrals and laboratory tests were higher in video visits compared to visit with medical device (OR of 1...
2024: Health Informatics Journal
https://read.qxmd.com/read/38586478/maternal-fetal-outcomes-in-patients-with-immune-mediated-inflammatory-diseases-with-consideration-of-comorbidities-a-retrospective-cohort-study-in-a-large-u-s-healthcare-system
#35
JOURNAL ARTICLE
Yeon Mi Hwang, Qi Wei, Samantha N Piekos, Bhargav Vemuri, Sevda Molani, Philip Mease, Leroy Hood, Jennifer Hadlock
BACKGROUND: Immune-mediated inflammatory diseases (IMIDs) are likely to complicate maternal health. However, literature on patients with IMIDs undergoing pregnancy is scarce and often overlooks the presence of comorbidities. We aimed to evaluate the impact of IMIDs on adverse pregnancy outcomes after assessing and addressing any discrepancies in the distribution of covariates associated with adverse pregnancy outcomes between patients with and without IMIDs. METHODS: We conducted a retrospective cohort study using data from an integrated U...
February 2024: EClinicalMedicine
https://read.qxmd.com/read/38585840/differences-in-covid-19-vaccination-and-experiences-among-patients-with-hypertension-in-colombia-and-jamaica-during-the-covid-19-pandemic
#36
Jacqueline P Duncan, Siyi Geng, Carene Lindsay, Trevor Ferguson, Katherine Mills, Jose Patricio Lopez-Lopez, Hua He, Paola Lanza, Makeda Williams, Veronica Tutse-Tonwe, Mabel Reyes, Alfonso Campo, Allison Marshall, Patricio Lopez-Jaramillo, Marshall K Tulloch-Reid
BACKGROUND: COVID-19 vaccination and shielding targeted hypertensive patients in low and middle income countries. We describe the COVID-19 experiences of hypertensive patients in Colombia and Jamaica and discuss factors associated with vaccine acceptance. METHODS: A cross-sectional study was conducted between December 2021 and February 2022 in 4 randomly selected primary care clinics in Colombia and 10 primary care clinics in Jamaica. Participants in Colombia were randomly selected from an electronic medical record...
March 26, 2024: medRxiv
https://read.qxmd.com/read/38584085/-concordance-of-medication-prescription-records-in-the-hospitalised-surgical-patient
#37
JOURNAL ARTICLE
O Guillén Martínez, M J Lucas Mayol, M Rodríguez Morote, L Soriano-Irigaray, C Matoses-Chirivella, A Navarro Ruiz
INTRODUCTION: Electronic prescription is the prescription system that allows healthcare professionals to send medication prescriptions directly to community pharmacies and the outpatient unit of Hospital Pharmacy Services for dispensing. However, there is difficulty in obtaining a reliable pharmacotherapeutic history in chronic patients through electronic prescription upon hospital admission as a critical point for adequate treatment adaptation. Therefore, the pharmacist as a member of the multidisciplinary team must ensure, through medication conciliation, an adequate transition of care through the correct management of the treatment that the chronic patient requires during their hospitalization...
April 6, 2024: Journal of Healthcare Quality Research
https://read.qxmd.com/read/38583899/prescription-opioid-use-increases-resource-utilization-following-ventral-hernia-repair
#38
JOURNAL ARTICLE
Skyler Palmer, Margaret Plymale, Anthony Mangino, Daniel Davenport, John Scott Roth
BACKGROUND: Previous studies showed that preoperative opioid use is associated with increased postoperative opioid use and surgical site infection (SSI) in patients undergoing ventral hernia repair (VHR). Orthopedic surgery literature cites increased resource utilization with opioid use. This study aimed to determine the effect of preoperative opioid use on resource utilization after open VHR. METHODS: A retrospective institutional review board-approved study of VHRs from a single tertiary care practice between 2013 and 2020 was performed...
April 2024: Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38582153/kai-xin-san-ameliorates-alzheimer-s-disease-related-neuropathology-and-cognitive-impairment-in-app-ps1-mice-via-the-mitochondrial-autophagy-nlrp3-inflammasome-pathway
#39
JOURNAL ARTICLE
Xiaoxiao Shan, Wenwen Tao, Junying Li, Wenkang Tao, Dawei Li, Lele Zhou, Xuan Yang, Chong Dong, Shunwang Huang, Xiaoqin Chu, Caiyun Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Kai-Xin-San (KXS) is a classic famous prescription that has been utilized for centuries to address dementia. New investigations have shown that the anti-dementia effect of KXS is connected with improved neuroinflammation. Nevertheless, the underlying mechanism is not well elucidated. AIM OF THE STUDY: We propose to discover the ameliorative impact of KXS on Alzheimer's disease (AD) and its regulatory role on the mitochondrial autophagy-nod-like receptor protein 3 (NLRP3) inflammasome pathway...
April 4, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38580433/sex-differences-in-the-intensity-of-statin-prescriptions-at-initiation-in-a-primary-care-setting
#40
JOURNAL ARTICLE
Pauline A J Kiss, Alicia Uijl, Annemarijn R de Boer, Tessa C X Duk, Diederick E Grobbee, Monika Hollander, Elisabeth Smits, Miriam C J M Sturkenboom, Sanne A E Peters
BACKGROUND: Current guidelines for the prevention and management of cardiovascular diseases (CVD) provide similar recommendations for the use of statins in both women and men. In this study, we assessed sex differences in the intensity of statin prescriptions at initiation and in the achievement of treatment targets, among individuals without and with CVD, in a primary care setting. METHODS: Electronic health record data from statin users were extracted from the PHARMO Data Network...
April 5, 2024: Heart
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