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https://www.readbyqxmd.com/read/29777388/a-retrospective-study-of-opioid-prescribing-patterns-at-hospital-discharge-in-surgical-patients-with-obstructive-sleep-apnea
#1
Samir M Kendale, Jing Wang, Jeanna D Blitz, Steven Calvino, Germaine Cuff, Nicholas Barone, Andrew D Rosenberg, Lisa Doan
PURPOSE: Obstructive sleep apnea (OSA) is a risk factor for complications with postoperative opioid use, and in those patients with known or suspected OSA, minimization of postoperative opioids is recommended. We hypothesize that despite these recommendations, surgical patients with known or suspected OSA are prescribed postoperative opioids at hospital discharge at similar doses to those without OSA. METHODS: This was a retrospective analysis of the electronic health records of surgical patients from 1 November 2016 to 30 April 2017 at a single academic institution...
May 18, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29777125/development-of-an-algorithm-to-identify-patients-with-physician-documented-insomnia
#2
Uri Kartoun, Rahul Aggarwal, Andrew L Beam, Jennifer K Pai, Arnaub K Chatterjee, Timothy P Fitzgerald, Isaac S Kohane, Stanley Y Shaw
We developed an insomnia classification algorithm by interrogating an electronic medical records (EMR) database of 314,292 patients. The patients received care at Massachusetts General Hospital (MGH), Brigham and Women's Hospital (BWH), or both, between 1992 and 2010. Our algorithm combined structured variables (such as International Classification of Diseases 9th Revision [ICD-9] codes, prescriptions, laboratory observations) and unstructured variables (such as text mentions of sleep and psychiatric disorders in clinical narrative notes)...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29775695/pulsatilla-decoction-inhibits-candida-albicans-proliferation-and-adhesion-in-a-mouse-model-of-vulvovaginal-candidiasis-via-the-dectin-1-signaling-pathway
#3
Lilin Yang, Haiwang Wu, Weiyu Qiu, Longyi Guo, Xin Du, Qingying Yu, Jie Gao, Songping Luo
ETHNOPHARMACOLOGICAL RELEVANCE: Pulsatilla decoction (PD) is a classical prescription in Traditional Chinese Medicine (TCM) and has been reported to have inhibitory effects on Candida albicans proliferation. STUDY AIM: To investigate the therapeutic effects of PD in the treatment of Vulvovaginal candidiasis (VVC) and elucidate the potential mechanism. MATERIALS AND METHODS: Female BALB/c mice (N=90) were randomized to six treatment groups, including the Control group, Model group, three PD groups and Fluconazole group which served as a positive control (20mg/kg weekly)...
May 15, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29772946/safety-and-effectiveness-of-apixaban-in-comparison-to-warfarin-in-patients-with-nonvalvular-atrial-fibrillation-a-propensity-matched-analysis-from-japanese-administrative-claims-data
#4
Shun Kohsaka, Jun Katada, Kumiko Saito, Yasuo Terayama
OBJECTIVE: To investigate the risk of bleeding events and stroke/systemic embolism (SE) among Japanese patients with nonvalvular atrial fibrillation (NVAF), focusing on the initial dosage of apixaban and patient age. METHODS: This retrospective cohort study used de-identified electronic health records-based claims data from 314 acute-care hospitals in Japan. NVAF patients newly initiated on warfarin or apixaban, with no prescription during the 180-day blanking period, were eligible...
May 18, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29772589/-optical-care-in-low-vision-patients
#5
Bettina von Livonius
The numbers of low vision patients will steadily increase because of increasing longevity. It is important to be aware of those patients so that visual rehabilitation can be started as soon as possible and needed. Before the adjustment of low vision devices a diagnosis should be confirmed in order to check any therapeutic option and to ensure the best individual rehabilitation. If there is no further therapeutic option left a detailed anamnesis of the problems due to low vision should be made to ensure that every patient gets the optical or electronic device he really needs in his everyday life...
May 17, 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29754716/sex-disparity-persists-in-the-prevention-of-cardiovascular-disease-in-women-on-statin-therapy-compared-to-that-in-men
#6
S Moreno-Arellano, J Delgado-de-Mendoza, M J Santi-Cano
BACKGROUND AND AIMS: The aim of this study was to assess whether women differ from men with regard to lowering lipid levels, achieving target of optimal lipid levels, and analyzing evidence-based dose and intensity of statin prescription in primary care patients. METHODS AND RESULTS: A multicenter cross-sectional survey was conducted among 1046 patients with dyslipidemia (554 women) who were receiving statin therapy from the Primary Health Care of Andalucía (Spain)...
April 7, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29754411/a-case-study-of-nurse-practitioner-care-compared-to-general-practitioner-care-for-children-with-respiratory-tract-infections
#7
Saskia F van Vugt, Alma C van de Pol, Frits G W Cleveringa, Rebecca K Stellato, Marieke P Kappers, Niek J de Wit, Roger A M J Damoiseaux
AIM: To compare quality of care provided by nurse practitioners with care provided by general practitioners for children with respiratory tract infections in the Netherlands. BACKGROUND: Nurse practitioners increasingly manage acute conditions in general practice, with opportunities for more protocolled care. Studies on quality of nurse practitioners' care for children with respiratory tract infections are limited to the US health care system and do not take into account baseline differences in illness severity...
May 13, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29752205/evaluation-of-the-frequency-of-dispensing-electronically-discontinued-medications-and-associated-outcomes
#8
Erin J Copi, Lindsey R Kelley, Kaleigh K Fisher
OBJECTIVES: To determine if outpatient pharmacies of an academic medical center inadvertently dispense discontinued medications and, if so, if these inadvertently dispensed prescriptions contribute to subsequent hospital admissions and patient harm. METHODS: This was a single-center retrospective chart review. Prescription billing data were analyzed for electronic prescriptions for hypotensives, hypoglycemics, anticoagulants, antiplatelets, and statins picked up from 3 outpatient pharmacies within the health system over a period of 1 year...
May 8, 2018: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29749124/development-of-algorithms-to-determine-the-onset-of-pregnancy-and-delivery-date-using-health-care-administrative-data-in-a-university-hospital-in-japan
#9
Tomofumi Ishikawa, Taku Obara, Hidekazu Nishigori, Keiko Miyakoda, Ryusuke Inoue, Tetsuro Hoshiai, Masatoshi Saito, Nobuo Yaegashi, Nariyasu Mano
PURPOSE: To develop and assess algorithms to determine the onset of pregnancy and delivery date using health administrative data from a university hospital in Japan. METHODS: All women who were hospitalized in the maternity ward and had at least one pregnancy that ended with a delivery during the period of January 2014 and December 2015 were included in this study. The true delivery date was obtained from the electronic medical records and was used as a gold standard...
May 11, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29748015/association-between-radiation-heart-dosimetric-parameters-myocardial-infarct-and-overall-survival-in-stage-3-non-small-cell-lung-cancer-treated-with-definitive-thoracic-radiotherapy
#10
Chia Ching Lee, Huili Zheng, Yu Yang Soon, Ling Li Foo, Wee Yao Koh, Cheng Nang Leong, Balamurugan Vellayappan, Jeremy Chee Seong Tey, Ivan Weng Keong Tham
OBJECTIVES: The aim of this retrospective observational study is to assess the association between various radiation heart dosimetric parameters (RHDPs) and acute myocardial infarct (AMI) and overall survival (OS) outcomes in stage III non-small cell lung cancer (NSCLC) treated with definitive radiotherapy with or without chemotherapy. MATERIALS AND METHODS: We identified eligible patients treated at two institutions from 2007 to 2014. We linked their electronic medical records to the national AMI and death registries...
June 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29746201/development-of-a-graphical-tool-to-measure-medication-adherence-in-asthma-patients-a-mixed-methods-pilot-study
#11
Alia Yousif, Catherine Lemière, André Cartier, Amélie Forget, Lucie Blais, For The Resp Investigators
OBJECTIVES: 1) To develop Med-Resp, a graphical tool based on prescription refills to measure adherence and use of asthma medications; 2) To test the feasibility of implementing Med-Resp in a hospital outpatient asthma clinic; 3) To explore the effectiveness of Med-Resp to improve medication adherence to asthma controller medications. METHODS: A sequential exploratory design was used: 1) Prototype design in collaboration with respiratory physicians and patients via focus groups; 2) Med-Resp creation based on algorithms developed and applied to prescription refills data recorded in the drug claims database reMed; 3) Feasibility assessment of the implementation of Med-Resp in the outpatient asthma clinic; and 4) Exploration of the effectiveness of Med-Resp through a pre-post design...
May 10, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29745772/specificity-elicits-higher-maximal-and-submaximal-cardiorespiratory-responses-during-a-new-taekwondo-aerobic-test
#12
Matheus Hausen, Pedro Paulo Soares, Marcus Paulo Araujo, Débora Esteves, Hilbert Julio, Roberto Tauil, Marcus Junca, Flávia Porto, Emerson Franchini, Craig Alan Bridge, Jonas Gurgel
PURPOSE: The purpose of the present study was to propose and validate new taekwondo-specific cardiopulmonary exercise tests. METHODS: Twelve male national-level taekwondo athletes (age 20 ± 2 yrs; body mass 67.5 ± 5.7 kg; height 175 ± 8 cm; training experience 7 ± 3 yrs) performed three separate exercise tests in a randomized counterbalanced order: 1) a Treadmill Running Cardiopulmonary Exercise Test (CPET); 2) Continuous and 3) Interval Taekwondo Cardiopulmonary Exercise Tests (cTKDet and iTKDet, respectively)...
May 10, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29743331/what-is-the-quality-of-reporting-on-guideline-protocol-or-algorithm-implementation-in-adult-trauma-centres-protocol-for-a-systematic-review
#13
Lesley Gotlib Conn, Avery B Nathens, Laure Perrier, Barbara Haas, Aaron Watamaniuk, Diego Daniel Pereira, Ashley Zwaiman, Luis Teodoro da Luz
INTRODUCTION: Quality improvement (QI) is mandatory in trauma centres but there is no prescription for doing successful QI. Considerable variation in implementation strategies and inconsistent use of evidence-based protocols therefore exist across centres. The quality of reporting on these strategies may limit the transferability of successful initiatives across centres. This systematic review will assess the quality of reporting on guideline, protocol or algorithm implementation within a trauma centre in terms of the Revised Standards for Quality Improvement Reporting Excellence (SQUIRE 2...
May 9, 2018: BMJ Open
https://www.readbyqxmd.com/read/29740916/real-world-management-of-pregestational-diabetes-not-achieving-glycemic-control-for-many-patients-in-the-uk
#14
Lucia Cea-Soriano, Luis A García-Rodríguez, Kimberly G Brodovicz, Elvira Gonzalez-Masso, Dorothee B Bartels, Sonia Hernández-Díaz
PURPOSE: Our goal was to describe the management of pregestational diabetes in pregnant women in the United Kingdom. METHODS: We used electronic medical records from The Health Improvement Network database between January 1995 and June 2012 to identify the first pregnancy in women 15 to 45 years of age with pregestational diabetes type 1 or type 2. Information on lifestyle factors, demographic characteristics, prescription of specific antidiabetic medications, and glycemic control measures (HbA1c) was obtained from primary care provider records...
May 8, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29740788/behavioral-economics-interventions-to-improve-outpatient-antibiotic-prescribing-for-acute-respiratory-infections-a-cost-effectiveness-analysis
#15
Cynthia L Gong, Kenneth M Zangwill, Joel W Hay, Daniella Meeker, Jason N Doctor
BACKGROUND: Behavioral economics interventions have been shown to effectively reduce the rates of inappropriate antibiotic prescriptions for acute respiratory infections (ARIs). OBJECTIVE: To determine the cost-effectiveness of three behavioral economic interventions designed to reduce inappropriate antibiotic prescriptions for ARIs. DESIGN: Thirty-year Markov model from the US societal perspective with inputs derived from the literature and CDC surveillance data...
May 8, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29739776/prevalence-of-treatment-resistant-hypertension-after-considering-pseudo-resistance-and-morbidity-a-cross-sectional-study-in-irish-primary-care
#16
Peter Hayes, Monica Casey, Liam G Glynn, Gerard J Molloy, Hannah Durand, Eoin O'Brien, Eamon Dolan, John Newell, Andrew W Murphy
BACKGROUND: To confirm treatment-resistant hypertension (TRH), ambulatory blood pressure measurement (ABPM) must exclude white-coat hypertension (WCH), three or more medications should be prescribed at the optimal doses tolerated, and non-adherence and lifestyle should be examined. Most previous studies have not adequately considered pseudo-resistance and merely provide an apparent TRH (aTRH) prevalence figure. AIM: To conduct a cross-sectional study of the prevalence of aTRH in general practice, and then consider pseudo-resistance and morbidity...
May 8, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29737799/identifying-errors-in-meals-provided-to-and-sourced-by-patients-on-therapeutic-diets-in-hospital
#17
Megan Rattray, Ben Desbrow, Shelley Roberts
BACKGROUND AND OBJECTIVES: Patients requiring therapeutic diets in hospital are at risk of exposer to dietary errors that may pose an acute threat to their safety. This study aimed to determine the prevalence of meal-related errors among hospitalised patients prescribed therapeutic diets, following the implementation of an electronic foodservice system (EFS). METHODS AND STUDY DESIGN: This observational study involved six wards in a tertiary metropolitan hospital that used an EFS for meal ordering and plating...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29731947/patterns-of-antibiotic-prescription-in-children-tirana-albania-region
#18
Joana Mihani, Suela Këlliçi
BACKGROUND: Antibiotics (abx) constitute the most prescribed therapeutic agent in the world. There is little data regarding antibiotic consumption by young children in Albania. AIM: This study aims to evaluate antibiotic prescription in children in quantitative and qualitative terms, and therefore, propose recommendations to improve overall clinical outcomes. METHODS: A retrospective, cross-sectional drug utilisation study was conducted based on unreimbursed prescriptions collected in 25 pharmacies, randomly selected within the district of Tirana, during the period beginning December 2015 to January 2016...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29731180/validation-of-the-electronic-prescription-as-a-method-for-measuring-treatment-adherence-in-hypertension
#19
Emilio Márquez-Contreras, Lourdes de López García-Ramos, Nieves Martell-Claros, Vicente F Gil-Guillen, Sara Márquez-Rivero, Elena Pérez-López, Maria Angeles Garrido-Lopez, Celia Farauste, Adriana López-Pineda, José Joaquin Casado-Martinez, Domingo Orozco-Beltran, Jose A Quesada, Concepción Carratalá-Munuera
OBJECTIVE: To validate electronic prescriptions (e-prescriptions) as a method for measuring treatment adherence in patients with hypertension. METHODS: This prospective study initially included 120 patients treated for hypertension in primary care centers. Adherence was measured using the gold standard, the medication event monitoring system (MEMS), versus the index test, the e-prescription program, at baseline and at 6, 12, 18 and 24 months. We calculated the adherence rate using the MEMS and the medication possession ratio (MPR) for the e-prescriptions...
April 23, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29727588/disparities-in-hospital-smoking-cessation-treatment-by-immigrant-status
#20
Jenny Chen, Ellie Grossman, Alissa Link, Binhuan Wang, Scott Sherman
Despite the efficacy of nicotine replacement therapy (NRT) in promoting smoking cessation, no studies have been done to evaluate NRT prescribing rates among immigrants, a vulnerable minority population in the United States. The aim of this study is to explore for differences in NRT prescribing behavior by immigrant status. Participants were enrolled in a smoking cessation trial for hospitalized patients between July 2011 and April 2014 at two NYC hospitals. For this analysis, we used baseline data from patient surveys and electronic medical-record reviews to examine associations between immigrant status and prescription of NRT in-hospital and on discharge, as well as acceptance of NRT in-hospital...
May 4, 2018: Journal of Ethnicity in Substance Abuse
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