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Corin

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https://www.readbyqxmd.com/read/28106904/planned-early-delivery-versus-expectant-management-for-hypertensive-disorders-from-34-weeks-gestation-to-term
#1
REVIEW
Catherine Cluver, Natalia Novikova, Corine M Koopmans, Helen M West
BACKGROUND: Hypertensive disorders in pregnancy are significant contributors to maternal and perinatal morbidity and mortality. These disorders include well-controlled chronic hypertension, gestational hypertension (pregnancy-induced hypertension) and mild pre-eclampsia. The definitive treatment for these disorders is planned early delivery and the alternative is to manage the pregnancy expectantly if severe uncontrolled hypertension is not present, with close maternal and fetal monitoring...
January 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28106289/the-involvement-of-corin-in-the-progression-of-diabetic-erectile-dysfunction-in-a-rat-model-by-down-regulating-anp-no-cgmp-signal-pathway
#2
Jian Wang, Yuanyuan Mi, Fenglai Yuan, Sheng Wu, Xiaoming You, Feng Dai, Yi Huang, Jia Cao, Jin Zhu, Boxin Xue, Lijie Zhu
This study was aimed to analyze the potential role of Corin in the procession of diabetic ED and to explore the underlying mechanism. Diabetic ED rat model was constructed and the characteristics of diabetic ED and control rats were recorded at 4, 8, 12 and 16 weeks. qRT-PCR and Western bloting were used to detected the mRNA and protein levels. Intracellular cGMP detection was accomplished using a commercial radioimmunoassay method. Vascular endothelial cell from rat corpus cavernosum spiral artery was isolated and transfected with si- Corin to analyzed the potential role of Corin...
January 20, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28096983/pde3-inhibition-with-enoximone-as-first-line-therapy-for-severe-persistent-pulmonary-hypertension-of-the-newborn-during-neonatal-transport-a-case-report
#3
Robin van der Lee, Barbara Peels, Corine Koopman-Esseboom
Severe Persistent pulmonary hypertension of the newborn (PPHN) can be effectively treated with a PDE3 inhibitor as first-line treatment during neonatal transport when iNO is not readily available. Starting iNO as soon as possible is strongly advised because of the complementary actions of both therapeutics.
January 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28087472/extract-of-clinopodium-bolivianum-protects-against-e-coli-invasion-of-uroepithelial-cells
#4
Soumitra Mohanty, Witchuda Kamolvit, Silvia Zambrana, Corine Sandström, Eduardo Gonzales, Claes-Göran Östenson, Annelie Braunerf
ETHNOPHARMACOLOGICAL RELEVANCE: Clinopodium bolivianum is a South American plant with anti-inflammatory and anti-infective activities. The increasing antibiotic resistance urges for alternative therapy. Based on its use in traditional medicine, we investigated the effect of C. bolivianum on the ability to defend bladder epithelial cells from E. coli infection. MATERIALS AND METHODS: The extract was analysed by LC-MS. Bladder epithelial cell lines T24 and 5637 and uropathogenic E...
January 10, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28062734/the-performance-of-the-alere-hiv-combo-point-of-care-test-on-stored-serum-samples-useful-for-detection-of-early-hiv-1-infections
#5
Carla van Tienen, Sharona Rugebregt, Sandra Scherbeijn, Hannelore Götz, Corine Geurts van Kessel
INTRODUCTION: The Alere HIV-1/2 Antigen/Antibody Combo point-of-care test is a commercially available 4th-generation rapid test for the diagnosis of HIV infection, including acute infection. We evaluated the sensitivity of this test in samples from patients with acute, recent or chronic HIV-1 infection. METHODS: A validation of the test was performed using 89 HIV-positive serum samples collected in 2008-2016, that were stored at -20°C. Twenty-three samples were only p24-positive (acute infection); 49 samples were antibody-positive and p24-positive (recent infection); 17 samples were only antibody-positive (chronic infection)...
January 6, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28036120/associations-of-pain-intensity-and-pain-related-disability-with-psychological-and-socio-demographic-factors-in-patients-with-temporomandibular-disorders-a-cross-sectional-study-at-a-specialized-dental-clinic
#6
Naichuan Su, Frank Lobbezoo, Arjen van Wijk, Geert J M G van der Heijden, Corine M Visscher
The study assessed whether psychological and socio-demographic factors, including somatization, depression, stress, anxiety, daytime sleepiness, optimism, gender and age are associated with pain intensity and pain-related disability in patients with temporomandibular disorders (TMD). In total, 320 TMD patients were involved in the study. The psychological status of each patient was assessed with questionnaires, including the Symptom Checklist-90 (SCL-90), Epworth Sleeping Scale (ESS), stress questionnaire, and Life Orientation Test-Revised (LOT-R)...
December 30, 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28033198/assessment-of-biopsychosocial-complexity-and-health-care-needs-measurement-properties-of-the-intermed-self-assessment-version-imsa
#7
Arianne K B van Reedt Dortland, Lilian L Peters, Annette D Boenink, Jan H Smit, Joris P J Slaets, Adriaan W Hoogendoorn, Andreas Joos, Corine H M Latour, Friedrich Stiefel, Cyrille Burrus, Marie Guitteny-Collas, Silvia Ferrari
OBJECTIVES: The INTERMED Self-Assessment questionnaire (IMSA) was developed as an alternative to the observer-rated INTERMED (IM) to assess biopsychosocial complexity and health care needs. We studied feasibility, reliability and validity of the IMSA within a large and heterogeneous international sample of adult hospital in- and outpatients, and its predictive value for health care utilization (HCU) and quality of life (QoL). METHODS: 850 participants aged 17 to 90 from 5 countries completed the IMSA and were evaluated with the IM...
December 28, 2016: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28029553/somatic-mutation-detection-using-various-targeted-detection-assays-in-paired-samples-of-circulating-tumor-dna-primary-tumor-and-metastases-from-patients-undergoing-resection-of-colorectal-liver-metastases
#8
Nick Beije, Jean C Helmijr, Marjolein J A Weerts, Corine M Beaufort, Matthew Wiggin, Andre Marziali, Cornelis Verhoef, Stefan Sleijfer, Maurice P H M Jansen, John W M Martens
Assessing circulating tumor DNA (ctDNA) is a promising method to evaluate somatic mutations from solid tumors in a minimally-invasive way. In a group of twelve metastatic colorectal cancer (mCRC) patients undergoing liver metastasectomy, from each patient DNA from cell-free DNA (cfDNA), the primary tumor, metastatic liver tissue, normal tumor-adjacent colon or liver tissue, and whole blood were obtained. Investigated was the feasibility of a targeted NGS approach to identify somatic mutations in ctDNA. This targeted NGS approach was also compared with NGS preceded by mutant allele enrichment using synchronous coefficient of drag alteration technology embodied in the OnTarget assay, and for selected mutations with digital PCR (dPCR)...
October 10, 2016: Molecular Oncology
https://www.readbyqxmd.com/read/28002537/cerebral-arteriopathy-with-subcortical-infarcts-and-leukoencephalopathy-in-acromegalic-patient-with-severe-headache
#9
LuminiŢa Nicoleta Cima, Simona Vasilica Fica, Alice Ioana Albu, Ioana Maria Lambrescu, Ioana SmărăndiŢa Lăcău, Bogdan Ovidiu Popescu, Mihaela Gherghiceanu, Corin Virgil Badiu, Carmen Gabriela Barbu
A 68-year-old female patient was admitted in our clinic with severe frontal bilateral headache, dizziness, depression and cognitive decline in the context of a previously diagnosed acromegaly. She also had high blood pressure, dyslipidemia, secondary diabetes mellitus. Acromegaly was caused by a growth hormone (GH) secreting-pituitary macroadenoma, so a transsphenoidal surgery was performed. The postoperative magnetic resonance imaging (MRI) scan revealed a 20÷22÷25 mm pituitary mass remnant and medical therapy with somatostatin analogues (SSAs) was started...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28002094/the-association-between-headaches-and-temporomandibular-disorders-is-confounded-by-bruxism-and-somatic-complaints
#10
Hedwig A van der Meer, Caroline M Speksnijder, Raoul Engelbert, Frank Lobbezoo, Maria W G Nijhuis-van der Sanden, Corine M Visscher
OBJECTIVES: The objective of this observational study was to establish the possible presence of confounders on the association between temporomandibular disorders (TMD) and headaches in a patient population from a TMD and Orofacial Pain Clinic. METHODS: Several subtypes of headaches were diagnosed: self-reported headache, (probable) migraine, (probable) tension-type headache (TTH), and secondary headache attributed to TMD. The presence of TMD was subdivided into two subtypes: painful TMD and function-related TMD...
December 19, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27988009/nmr-study-of-hydroxy-and-amide-protons-in-hyaluronan-polymers
#11
Gustav Nestor, Corine Sandström
Hyaluronan (HA) is an important and well characterized glycosaminoglycan with high viscosity and water-retaining capacity. Nonetheless, it is not fully understood whether conformational properties of the easily characterized HA oligomers can be transferred to HA polymers. To investigate possible differences in hydration, hydrogen bonding and flexibility between HA polymers and oligomers, hydroxy and amide protons of HA polymers were studied by solution-state and high-resolution magic angle spinning (HR-MAS) NMR spectroscopy...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27987864/1d-nmr-methods-for-determination-of-degree-of-cross-linking-and-bdde-substitution-positions-in-ha-hydrogels
#12
Frida J Wende, Suresh Gohil, Lars I Nord, Anne Helander Kenne, Corine Sandström
Hyaluronic acid polymers cross-linked with BDDE are today among the most used hydrogels for biomedical applications. The physical properties of the hydrogels depend, among other parameters, on the degree of cross-linking of HA. Another parameter likely to affect the physical properties is the substitution position of the linker on the HA functional groups. A NMR-based method for the determination of these parameters in hyaluronic acid hydrogels is presented. The method is based on the degradation of HA cross linked hydrogels by chondroitinase ABC followed by one-dimensional (1)H and (13)C NMR analysis...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27965530/the-effect-of-physical-therapy-treatment-in-patients-with-subjective-tinnitus-a-systematic-review
#13
REVIEW
Sarah Michiels, Sebastiaan Naessens, Paul Van de Heyning, Marc Braem, Corine M Visscher, Annick Gilles, Willem De Hertogh
Background: Tinnitus is a very common symptom that often causes distress and decreases the patient's quality of life. Apart from the well-known causes, tinnitus can in some cases be elicited by dysfunctions of the cervical spine or the temporomandibular joint (TMJ). To date however, it is unclear whether alleviation of these dysfunctions, by physical therapy treatment, also decreases the tinnitus complaints. Such physical therapy could be an interesting treatment option for patients that are now often left without treatment...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27912127/hyperferritinemia-is-a-potential-marker-of-chronic-chikungunya-a-retrospective-study-on-the-island-of-cura%C3%A3-ao-during-the-2014-2015-outbreak
#14
Fatih Anfasa, Lisette Provacia, Corine GeurtsvanKessel, Robert Wever, Izzy Gerstenbluth, Albert D M E Osterhaus, Byron E E Martina
BACKGROUND: Recently Chikungunya virus (CHIKV) outbreaks have been reported in the Carribean. There is no data regarding the outbreak in Curaçao. In addition, to date there is no biomarker that could be used to predict chronic infection. OBJECTIVES: To characterize the first CHIKV outbreak in Curaçao and to identify potential biomarkers for chronic infection. STUDY DESIGN: A serological test and quantitative polymerase chain reaction (qPCR) were used on samples collected in Curaçao to confirm infection...
January 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/27911005/adsorption-as-a-contributor-for-inflammatory-mediators-removal-by-different-hemofiltration-membranes-a-pilot-study
#15
Benjamin Malard, Nans Florens, Corine Lambert, Laurent Juillard
Atherosclerosis is an important predictor of mortality in patients with chronic kidney disease (CKD) and is associated with a wide inflammatory response. The aim of this study is to evaluate in vitro how different membranes can remove mediators associated with this pathology in a closed loop dialysis model. We performed experimental hemofiltration in vitro using three different membrane materials. Human plasma was preliminarily incubated with various inflammatory mediators and filtered in a closed loop circulation model for 240 min...
December 2, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27908548/dietary-sodium-and-potassium-intakes-data-from-urban-and-rural-areas
#16
Carmelle Mizéhoun-Adissoda, Dismand Houinato, Corine Houehanou, Thierry Chianea, François Dalmay, André Bigot, Victor Aboyans, Pierre-Marie Preux, Pascal Bovet, Jean-Claude Desport
OBJECTIVES: Hypertension is highly prevalent in West African populations, but little data is available on salt and potassium intake in these populations. We assumed in this study that sodium and potassium intake might be high and low, respectively, in the Beninese population in view of the emerging nutritional transition. The aim of this study was to estimate dietary sodium and potassium intakes based on 24-h urine collections. METHODS: We selected 420 individuals (ages 25-64 y), representative of the population, from urban and rural areas in Benin...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27905919/susceptibility-of-anopheles-gambiae-to-insecticides-used-for-malaria-vector-control-in-rwanda
#17
Emmanuel Hakizimana, Corine Karema, Dunia Munyakanage, Gad Iranzi, John Githure, Jon Eric Tongren, Willem Takken, Agnes Binagwaho, Constantianus J M Koenraadt
BACKGROUND: The widespread emergence of resistance to pyrethroids is a major threat to the gains made in malaria control. To monitor the presence and possible emergence of resistance against a variety of insecticides used for malaria control in Rwanda, nationwide insecticide resistance surveys were conducted in 2011 and 2013. METHODS: Larvae of Anopheles gambiae sensu lato mosquitoes were collected in 12 sentinel sites throughout Rwanda. These were reared to adults and analysed for knock-down and mortality using WHO insecticide test papers with standard diagnostic doses of the recommended insecticides...
December 1, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27904171/temporal-issues-in-person-organization-fit-person-job-fit-and-turnover-the-role-of-leader-member-exchange
#18
Corine Boon, Michal Biron
Person-environment fit has been found to have significant implications for employee attitudes and behaviors. Most research to date has approached person-environment fit as a static phenomenon, and without examining how different types of person-environment fit may affect each other. In particular, little is known about the conditions under which fit with one aspect of the environment influences another aspect, as well as subsequent behavior. To address this gap we examine the role of leader-member exchange in the relationship between two types of person-environment fit over time: person-organization and person-job fit, and subsequent turnover...
December 2016: Human Relations; Studies Towards the Integration of the Social Sciences
https://www.readbyqxmd.com/read/27898523/role-of-corin-in-the-regulation-of-blood-pressure
#19
Hui Li, Yue Zhang, Qingyu Wu
PURPOSE OF REVIEW: Corin is a transmembrane protease that activates atrial natriuretic peptide (ANP), an important hormone in regulating salt-water balance and blood pressure. This review focuses on the regulation of corin function and potential roles of corin defects in hypertensive, heart, and renal diseases. RECENT FINDINGS: Proprotein convertase subtilisin/kexin-6 has been identified as a primary enzyme that converts zymogen corin to an active protease. Genetic variants that impair corin intracellular trafficking, cell surface expression, and zymogen activation have been found in patients with hypertension, cardiac hypertrophy, and pre-eclampsia...
November 24, 2016: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/27892960/new-genome-wide-algorithm-identifies-novel-in-vivo-expressed-mycobacterium-tuberculosis-antigens-inducing-human-t-cell-responses-with-classical-and-unconventional-cytokine-profiles
#20
Mariateresa Coppola, Krista E van Meijgaarden, Kees L M C Franken, Susanna Commandeur, Gregory Dolganov, Igor Kramnik, Gary K Schoolnik, Inaki Comas, Ole Lund, Corine Prins, Susan J F van den Eeden, Gro E Korsvold, Fredrik Oftung, Annemieke Geluk, Tom H M Ottenhoff
New strategies are needed to develop better tools to control TB, including identification of novel antigens for vaccination. Such Mtb antigens must be expressed during Mtb infection in the major target organ, the lung, and must be capable of eliciting human immune responses. Using genome-wide transcriptomics of Mtb infected lungs we developed data sets and methods to identify IVE-TB (in-vivo expressed Mtb) antigens expressed in the lung. Quantitative expression analysis of 2,068 Mtb genes from the predicted first operons identified the most upregulated IVE-TB genes during in-vivo pulmonary infection...
November 28, 2016: Scientific Reports
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