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https://www.readbyqxmd.com/read/29131687/the-questionnaire-of-cognitive-and-affective-empathy-a-comparison-between-paper-and-pencil-versus-online-formats-in-italian-samples
#1
Marzia Di Girolamo, Luciano Giromini, Christina L Winters, Colinda M B Serie, Corine de Ruiter
The most recent conceptualizations of empathy recognize affective empathy as distinct from cognitive empathy. Consequently, instruments that assess these 2 types of empathy have been developed. Among them, the Questionnaire of Cognitive and Affective Empathy (QCAE) is a particularly promising, relatively new, self-report measure consisting of 31 items. To examine the cross-cultural adaptability of the QCAE, we investigated the psychometric properties of an Italian version in 2 samples and with 2 different formats of administration...
November 13, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29126994/a-dual-promoter-gene-orchestrates-the-sucrose-coordinated-synthesis-of-starch-and-fructan
#2
Yunkai Jin, Mingliang Fei, Sara Rosenquist, Lu Jin, Suresh Gohil, Corine Sandström, Helena Olsson, Cecilia Persson, Anna-Stina Höglund, Gunnel Fransson, Ying Ruan, Per Åman, Christer Jansson, Chunlin Liu, Roger Andersson, Chuanxin Sun
Sequential carbohydrate synthesis is important for plant survival because it guarantees energy supplies for growth and development during plant ontogeny and reproduction. Starch and fructan are two important carbohydrates in many flowering plants and in human diets. Understanding this coordinated starch and fructan synthesis and unravelling how plants allocate photosynthates and prioritize different carbohydrate synthesis for survival could lead to improvements to cereals in agriculture for the purposes of greater food security and production quality...
November 7, 2017: Molecular Plant
https://www.readbyqxmd.com/read/29122992/labile-plasma-iron-levels-predict-survival-in-patients-with-lower-risk-myelodysplastic-syndromes
#3
Louise de Swart, Chloé Reiniers, Timothy Bagguley, Corine van Marrewijk, David Bowen, Eva Hellström-Lindberg, Aurelia Tatic, Argiris Symeonidis, Gerwin Huls, Jaroslav Cermak, Arjan A van de Loosdrecht, Hege Garelius, Dominic Culligan, Mac Macheta, Michail Spanoudakis, Panagiotis Panagiotidis, Marta Krejci, Nicole Blijlevens, Saskia Langemeijer, Jacqueline Droste, Dorine W Swinkels, Alexandra Smith, Theo de Witte
Red blood cell transfusions remain one of the cornerstones in supportive care of lower-risk patients with myelodysplastic syndromes. We hypothesized that patients develop oxidant mediated tissue injury through the formation of toxic iron species, caused either by red blood cell transfusions or by ineffective erythropoiesis. We analyzed serum samples from 100 lower-risk patients with myelodysplastic syndromes at six-month intervals for transferrin saturation, hepcidin-25, growth differentiation factor 15, soluble transferrin receptor, non-transferrin bound iron and labile plasma iron in order to evaluate temporal changes in iron metabolism and presence of potentially toxic iron species and their impact on survival...
November 9, 2017: Haematologica
https://www.readbyqxmd.com/read/29121806/the-medical-care-of-male-and-female-youth-who-die-by-suicide-a-population-based-case-control-study
#4
Anne E Rhodes, Michael H Boyle, Jeffrey A Bridge, Mark Sinyor, Laurence Y Katz, Kathryn Bennett, Amanda S Newton, Paul S Links, Lil Tonmyr, Robin Skinner, Amy Cheung, Jennifer Bethell, Corine Carlisle
OBJECTIVE: Prior year medical care was compared among youth dying by suicide to their peers. Effect modification of these associations by age or place of residency (rural versus larger community sizes) was examined in a large, medically insured population. METHOD: This population-based case control study used data from the Office of the Chief Coroner in Ontario, Canada, linked to health care administrative data to examine associations between medical care for mental health or other reasons (versus no medical care) and suicide...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29120908/patients-beliefs-about-medicine-are-associated-with-early-thiopurine-discontinuation-in-patients-with-inflammatory-bowel-diseases
#5
Mark M T J Broekman, Marieke J H Coenen, Geert J Wanten, Corine J van Marrewijk, Wietske Kievit, Olaf H Klungel, André L M Verbeek, Dennis R Wong, Piet M Hooymans, Henk-Jan Guchelaar, Hans Scheffer, Luc J J Derijks, Marcel L Bouvy, Dirk J de Jong
BACKGROUND: Patients' beliefs about medicine may either reflect the necessity for treatment or concerns regarding the treatment. We explored the extent to which these beliefs have an effect on thiopurine metabolite levels and premature discontinuation in patients with inflammatory bowel disease (IBD). PATIENTS AND METHODS: Patients enrolled in the 'Thiopurine response Optimization by Pharmacogenetic testing in Inflammatory Bowel Disease Clinics' (TOPIC) trial were asked to complete the Beliefs about Medicine Questionnaire (BMQ) 4 weeks after thiopurine initiation...
November 8, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29110389/equivalence-testing-for-similarity-in-bioassays-using-bioequivalence-criteria-on-the-relative-bioactivity
#6
Corine Baljé-Volkers, Thembile Mzolo, Erik Talens, Pieta IJzerman-Boon, Edwin Van den Heuvel
Similarity in bioassays means that the test preparation behaves as a dilution of the standard preparation with respect to their biological effect. Thus, similarity must be investigated to confirm this biological property. Historically, this was typically conducted with traditional hypothesis testing, but this has received substantial criticism. Failing to reject similarity does not imply that the 2 preparations are similar. Also, rejecting similarity when bioassay variability is small might simply demonstrate a nonrelevant deviation in similarity...
November 6, 2017: Pharmaceutical Statistics
https://www.readbyqxmd.com/read/29101802/corin-protects-h2o2-induced-apoptosis-through-pi3k-akt-and-nf-%C3%AE%C2%BAb-pathway-in-cardiomyocytes
#7
Yansong Li, Jingwen Xia, Nianxin Jiang, Yuqiong Xian, Haining Ju, Yong Wei, Xuan Zhang
BACKGROUND: The functional role of corin in H2O2-induced apoptosis is largely unexplored. The present study investigated the protective role of corin against cell injury by possible involvement of PI3K/AKT and NF-kB signaling pathways in cardiomyocytes. METHOD: Cardiomyocytes H9c2 and HL-1 cells were used in the study. Cell viability was measured using CCK-8 assay; cell apoptosis was analyzed by flow cytometry, TUNEL assay, and western blot; and cell migration was measured using wound healing assay...
November 1, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29100899/comparative-pathogenesis-of-rabies-in-bats-and-carnivores-and-implications-for-spillover-to-humans
#8
REVIEW
Lineke Begeman, Corine GeurtsvanKessel, Stefan Finke, Conrad M Freuling, Marion Koopmans, Thomas Müller, Tom J H Ruigrok, Thijs Kuiken
Bat-acquired rabies is becoming increasingly common, and its diagnosis could be missed partly because its clinical presentation differs from that of dog-acquired rabies. We reviewed the scientific literature to compare the pathogenesis of rabies in bats and carnivores-including dogs-and related this pathogenesis to differences in the clinical presentation of bat-acquired and dog-acquired rabies in human beings. For bat-acquired rabies, we found that the histological site of exposure is usually limited to the skin, the anatomical site of exposure is more commonly the face, and the virus might be more adapted for entry via the skin than for dog-acquired rabies...
October 31, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29092216/germanium-on-silicon-waveguides-operating-at-mid-infrared-wavelengths-up-to-8-5-%C3%AE-m
#9
Milos Nedeljkovic, Jordi Soler Penades, Vinita Mittal, Ganapathy Senthil Murugan, Ali Z Khokhar, Callum Littlejohns, Lewis G Carpenter, Corin B E Gawith, James S Wilkinson, Goran Z Mashanovich
We report transmission measurements of germanium on silicon waveguides in the 7.5-8.5 μm wavelength range, with a minimum propagation loss of 2.5 dB/cm at 7.575 μm. However, we find an unexpected strongly increasing loss at higher wavelengths, potential causes of which we discuss in detail. We also demonstrate the first germanium on silicon multimode interferometers operating in this range, as well as grating couplers optimized for measurement using a long wavelength infrared camera. Finally, we use an implementation of the "cut-back" method for loss measurements that allows simultaneous transmission measurement through multiple waveguides of different lengths, and we use dicing in the ductile regime for fast and reproducible high quality optical waveguide end-facet preparation...
October 30, 2017: Optics Express
https://www.readbyqxmd.com/read/29076023/thermal-map-assessment-under-climate-and-land-use-changes-a-case-study-for-uzundere-basin
#10
Nalan Demircioglu Yıldız, Ugur Avdan, Sevgi Yılmaz, Andreas Matzarakis
Satellite images are commonly used for defining thermal urban environment and heat islands in urban areas. The objective of this study was to analyze and evaluate thermal environment of Uzundere-Erzurum using satellite images provided by the Landsat Thematic Mapper (TM) sensor on board Landsat 5 satellite. In respect to land use and urban surface features, spatial characterization of thermal urban environment was defined. In order to define the link between surface emissivity, land surface temperatures (LST), and urban surface characteristics more effectively, the CORINE Land Cover (CLC) database for Uzundere was also used...
October 26, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29071080/description-of-the-protocol-for-the-practical-study-a-randomised-controlled-trial-of-the-efficacy-and-safety-of-ics-laba-reliever-therapy-in-asthma
#11
James Fingleton, Jo Hardy, Christina Baggott, Janine Pilcher, Andrew Corin, Robert J Hancox, Matire Harwood, Mark Holliday, Helen K Reddel, Philippa Shirtcliffe, Suzanne Snively, Mark Weatherall, Richard Beasley
INTRODUCTION: In adult asthma, combination inhaled corticosteroid (ICS)/fast-onset long-acting beta agonist (LABA) used solely as reliever therapy may represent an effective and safe alternative to ICS maintenance and short-acting beta agonist (SABA) reliever therapy. OBJECTIVE: To compare the efficacy and safety of ICS/fast-onset LABA reliever therapy with ICS maintenance and SABA reliever therapy in adults with asthma. METHODS AND ANALYSIS: A 52-week, open-label, parallel group, multicentre, phase III randomised controlled trial with 1:1 randomisation to either budesonide/formoterol Turbuhaler 200/6 µg, one actuation as required for symptom relief, or budesonide Turbuhaler 200 µg, one actuation twice daily and terbutaline Turbuhaler 250 µg, two actuations as required for symptom relief...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/29065320/perceptions-of-community-care-and-placement-preferences-in-first-year-nursing-students-a-multicentre-cross-sectional-study
#12
Margriet van Iersel, Corine H M Latour, Rien de Vos, Paul A Kirschner, Wilma J M Scholte Op Reimer
BACKGROUND: Despite increasing shortages of highly educated community nurses, far too few nursing students choose community care. This means that a strong societal problem is emerging that desperately needs resolution. OBJECTIVES: To acquire a solid understanding of the causes for the low popularity of community care by exploring first-year baccalaureate nursing students' perceptions of community care, their placement preferences, and the assumptions underlying these preferences...
October 4, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29053717/gpr40-partial-agonists-and-agopams-differentiating-effects-on-glucose-and-hormonal-secretions-in-the-rodent
#13
Michele J Pachanski, Melissa E Kirkland, Daniel T Kosinski, Joel Mane, Boonlert Cheewatrakoolpong, Jiyan Xue, Daphne Szeto, Gail Forrest, Corin Miller, Michelle Bunzel, Christopher W Plummer, Harry R Chobanian, Michael W Miller, Sarah Souza, Brande S Thomas-Fowlkes, Aimie M Ogawa, Adam B Weinglass, Jerry Di Salvo, Xiaoyan Li, Yue Feng, Daniel A Tatosian, Andrew D Howard, Steven L Colletti, Maria E Trujillo
GPR40 agonists are effective antidiabetic agents believed to lower glucose through direct effects on the beta cell to increase glucose stimulated insulin secretion. However, not all GPR40 agonists are the same. Partial agonists lower glucose through direct effects on the pancreas, whereas GPR40 AgoPAMs may incorporate additional therapeutic effects through increases in insulinotrophic incretins secreted by the gut. Here we describe how GPR40 AgoPAMs stimulate both insulin and incretin secretion in vivo over time in diabetic GK rats...
2017: PloS One
https://www.readbyqxmd.com/read/29048691/is-a-short-stem-suitable-for-patients-with-hip-dysplasia-a-report-on-technical-problems-encountered-during-femoral-reconstruction
#14
Martin A Buttaro, Pablo A Slullitel, Gerardo Zanotti, Fernando M Comba, Francisco Piccaluga
INTRODUCTION: A wide variety of stems have been used for the treatment of osteoarthritis secondary to advanced hip dysplasia. Since evidence for using short stems in dysplastic hips is limited, we planned to analyse the technical problems encountered when reconstructing the proximal femur of patients with osteoarthritis secondary to congenital dysplasia of the hip treated with total hip arthroplasty (THA) using a type 2B short stem. METHODS: We prospectively analysed 17 patients (22 hips) treated with primary THA performed with a single-branded short uncemented stem with metaphyseal fixation (MiniHip™; Corin)...
October 14, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29024761/pattern-of-closure-of-skull-base-synchondroses-in-crouzon-syndrome
#15
Guillaume Coll, Laurent Sakka, Céline Botella, Nathalie Pham-Dang, Corine Collet, Michel Zerah, Eric Arnaud, Federico Di Rocco
BACKGROUND: The age of closure of skull base synchondroses has never been analyzed in a homogenous population of children with Crouzon syndrome. METHOD: A retrospective case-control study was performed on 30 Crouzon children (17M, 13F) aged 1 month to 12.48 years with Fibroblast Growth Factor Receptor type 2 mutation. Eleven synchondroses were analyzed on millimetric computed tomodensitometry slices before surgery. Syndromic patients were compared to a series of 235 healthy children previously published...
October 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29021388/in-vivo-beta-and-gamma-subthreshold-oscillations-in-rat-mitral-cells-origin-and-gating-by-respiratory-dynamics
#16
Nicolas Fourcaud-Trocmé, Virginie Briffaud, Marc Thévenet, Nathalie Buonviso, Corine Amat
In mammals, olfactory bulb (OB) dynamics are paced by slow and fast oscillatory rhythms at multiple levels: local field potential, spike discharge, and/or membrane potential oscillations. Interactions between these levels have been well studied for the slow rhythm linked to animal respiration. However, less is known regarding rhythms in the fast beta (10-35Hz) and gamma (35-100Hz) frequency ranges, particularly at the membrane potential level. Using a combination of intracellular and extracellular recordings in the OB of freely breathing rats, we show that beta and gamma subthreshold oscillations (STO) coexist intracellularly and are related to extracellular LFP oscillations in the same frequency range...
October 11, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29019474/are-pain-related-temporomandibular-disorders-the-product-of-an-interaction-between-psychological-factors-and-self-reported-bruxism
#17
Maurits Ka van Selms, Konstantin Muzalev, Corine M Visscher, Michail Koutris, Melike Bulut, Frank Lobbezoo
AIMS: To investigate whether pain-related temporomandibular disorders (TMD) are the product of an interaction between psychological factors and self-reported bruxism activities. METHODS: Patients referred to a specialized clinic for complaints of orofacial pain and dysfunction completed a digital questionnaire prior to the first clinical visit. The patient sample was then split into a case group consisting of 268 patients diagnosed with TMD pain according to the Diagnostic Criteria for Temporomandibular Disorders (85...
2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29018187/interconnected-subsets-of-memory-follicular-helper-t-cells-have-different-effector-functions
#18
Assia Asrir, Meryem Aloulou, Mylène Gador, Corine Pérals, Nicolas Fazilleau
Follicular helper T cells regulate high-affinity antibody production. Memory follicular helper T cells can be local in draining lymphoid organs and circulate in the blood, but the underlying mechanisms of this subdivision are unresolved. Here we show that both memory follicular helper T subsets sustain B-cell responses after reactivation. Local cells promote more plasma cell differentiation, whereas circulating cells promote more secondary germinal centers. In parallel, local memory B cells are homogeneous and programmed to become plasma cells, whereas circulating memory B cells are able to rediversify...
October 10, 2017: Nature Communications
https://www.readbyqxmd.com/read/28990918/impact-evaluation-of-malaria-control-interventions-on-morbidity-and-all-cause-child-mortality-in-rwanda-2000-2010
#19
Erin Eckert, Lia S Florey, Jon Eric Tongren, S René Salgado, Alphonse Rukundo, Jean Pierre Habimana, Emmanuel Hakizimana, Kaendi Munguti, Noella Umulisa, Monique Mulindahabi, Corine Karema
The impressive decline in child mortality that occurred in Rwanda from 1996-2000 to 2006-2010 coincided with a period of rapid increase of malaria control interventions such as indoor residual spraying (IRS); insecticide-treated net (ITN) distribution and use, and improved malaria case management. The impact of these interventions was examined through ecological correlation analysis, and robust decomposition analysis of contextual factors on all-cause child mortality. Child mortality fell 61% during the evaluation period and prevalence of severe anemia in children 6-23 months declined 71% between 2005 and 2010...
September 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28990618/direct-crystallographic-evidence-of-the-reversible-photo-formation-and-thermo-rupture-of-a-coordination-bond-inducing-spin-crossover-phenomenon
#20
David Aguilà, Pierre Dechambenoit, Mathieu Rouzières, Corine Mathonière, Rodolphe Clérac
A detailed crystallographic study of [Fe(II)(LN5)(CN)2]·MeOH (LN5 = 2,13-dimethyl-3,6,9,12,18-pentaazabicyclo[12.3.1]octadeca-1(18),2,12,14,16-pentaene) shows the light-induced formation and thermally-assisted rupture of a metal-ligand coordination bond concomitantly with a spin-crossover process occurring at the Fe(ii) center between its low spin (LS) and high spin (HS) states. These results illustrate the remarkable reversibility and non-destructive character of this photo-induced magneto-structural process in a single crystal...
October 19, 2017: Chemical Communications: Chem Comm
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