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Cognitive Assessment

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https://www.readbyqxmd.com/read/28102890/handgrip-strength-in-old-and-very-old-adults-mood-cognition-function-and-mortality
#1
Jochanan Stessman, Yakir Rottenberg, Matan Fischer, Aliza Hammerman-Rozenberg, Jeremy M Jacobs
OBJECTIVES: To determine the trajectory of handgrip strength (HGS) from age 70 to 90 and its association with mood, cognition, functional status, and mortality. DESIGN: Prospective follow-up of an age-homogenous representative community-dwelling cohort (born 1920-21) in the Jerusalem Longitudinal Cohort Study (1990-2015). SETTING: Home-based assessment. PARTICIPANTS: Subjects aged 70 (n = 327), 78 (n = 384), 85 (n = 1187), and 90 (n = 406), examined in 1990, 1998, 2005, and 2010, respectively...
January 19, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28102888/genetic-polymorphisms-in-estrogen-metabolic-pathway-associated-with-risks-of-alzheimer-s-disease-evidence-from-a-southern-chinese-population
#2
Lu Hua Chen, Yan Hui Fan, Patrick Yu Ping Kao, Deborah Tip Yin Ho, Joyce Cheuk Tung Ha, Leung Wing Chu, You-Qiang Song
OBJECTIVES: To investigate whether genetic variations on the estrogen metabolic pathway would be associated with risk of Alzheimer's disease (AD). DESIGN: Cross-sectional study. SETTING: Individuals were recruited at the Memory Clinic, Queen Mary Hospital, Hong Kong. PARTICIPANTS: Chinese individuals with (n = 426) and without (n = 350) AD. MEASUREMENTS: All subjects underwent a standardized cognitive assessment and genotyping of four candidate genes on the estrogen metabolic pathway (estrogen receptor α gene (ESR1), estrogen receptor β gene (ESR2), cytochrome P450 19A1 gene (CYP19A1), cytochrome P450 11A1 gene (CYP11A1))...
January 19, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28102739/perceptions-of-mild-traumatic-brain-injury-in-adults-a-scoping-review
#3
Katie Mah, Andrea Hickling, Nick Reed
PURPOSE: The purpose of this article is to synthesise the scholarly literature related to perceptions of mild traumatic brain injury (mTBI) and health outcomes in an adult population. METHODS: A scoping review was undertaken. An electronic search of seven databases was conducted. Studies were included if (1) they related to perceptions of mild traumatic brain injury, (2) the population was adults with mild traumatic brain injury, and (3) health outcomes were reported...
January 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28102714/validity-and-reliability-of-a-questionnaire-to-assess-social-skills-in-traumatic-brain-injury-a-preliminary-study
#4
Heather M Francis, Katherine Osborne-Crowley, Skye McDonald
OBJECTIVE: To describe the reliability and validity of a new measure, the Social Skills Questionnaire for Traumatic Brain Injury (SSQ-TBI). METHODS: Fifty-one adults with severe TBI completed the SSQ-TBI questionnaire. Scores were compared to informant- and self-report on questionnaires addressing frontal lobe mediated behaviour, as well as performance on an objective measure of social cognition and neuropsychological tasks, in order to provide evidence of concurrent, divergent and predictive validity...
January 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28102697/goal-intention-reminding-in-traumatic-brain-injury-a-feasibility-study-using-implementation-intentions-and-text-messaging
#5
Tessa Hart, Monica J Vaccaro
OBJECTIVE: To examine feasibility of participant-created implementation intentions, delivered as text message reminders, to enhance goal-related activity in persons with chronic, moderate/severe traumatic brain injury (TBI). DESIGN: Pilot randomized controlled trial on effects of 8 weeks receiving goal-related implementation intentions (GI) compared to control condition, educational review regarding goals (GR). PARTICIPANTS: Eight persons with moderate/severe TBI nearing discharge from intensive outpatient brain injury treatment...
January 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28102529/recovery-from-chemotherapy-induced-white-matter-changes-in-young-breast-cancer-survivors
#6
Thibo Billiet, Louise Emsell, Mathieu Vandenbulcke, Ronald Peeters, Daan Christiaens, Alexander Leemans, Wim Van Hecke, Ann Smeets, Frederic Amant, Stefan Sunaert, Sabine Deprez
In a previous longitudinal diffusion tensor imaging (DTI) study, we observed cerebral white matter (WM) alterations (reduced fractional anisotropy (FA)) related to decreased cognitive performance 3-5 months after chemotherapy-treatment (t2) when compared to baseline (t1) (Deprez et al. in Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 30(3), 274-281. doi:10.1200/JCO.2011.36.8571, 2012). The current study investigates the evolution and the nature of these previously observed microstructural changes...
January 19, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28102492/persistent-cognitive-deficits-after-whiplash-injury-a-comparative-study-with-mild-traumatic-brain-injury-patients-and-healthy-volunteers
#7
Kurt Beeckmans, Cleo Crunelle, Silke Van Ingelgom, Karla Michiels, Eva Dierckx, Patrick Vancoillie, Henri Hauman, Bernard Sabbe
In this study, we evaluated persistent cognitive deficits in whiplash injury (WI) patients and compared these to cognitive functioning in mild traumatic brain injury (MTBI) patients and healthy controls (HC). Sixty-one patients suffering from a WI were compared with 57 patients suffering from a MTBI and with 30 HC. They were examined with an extensive neuropsychological test battery assessing attention, memory, and visuospatial and executive functions. In both patient groups, participants showed persistent cognitive symptoms (more than 6 months post-injury)...
January 19, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28102474/anti-amnestic-effect-of-curcumin-in-combination-with-donepezil-an-anticholinesterase-drug-involvement-of-cholinergic-system
#8
Ayodele Jacob Akinyemi, Ganiyu Oboh, Sunday Idowu Oyeleye, Opeyemi Ogunsuyi
Recently, combination therapy involving cholinesterase (ChE) inhibitor with other neuroprotective agents has shown better desirable effect in the management/prevention of dementia but limited information is available on their effect with dietary polyphenols. Hence, this study sought to assess the combined pretreatment effect of curcumin, the major polyphenolic compound of turmeric (Curcuma longa) rhizomes, with donepezil, a cholinesterase inhibitor, on cognitive function in scopolamine-induced memory impairment in rats...
January 19, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/28102097/familiar-auditory-sensory-training-in-chronic-traumatic-brain-injury-a-case-study
#9
Emily Galassi Sullivan, Ann Guernon, Brett Blabas, Amy A Herrold, Theresa L-B Pape
PURPOSE: The evaluation and treatment for patients with prolonged periods of seriously impaired consciousness following traumatic brain injury (TBI), such as a vegetative or minimally conscious state, poses considerable challenges, particularly in the chronic phases of recovery. METHOD: This blinded crossover study explored the effects of familiar auditory sensory training (FAST) compared with a sham stimulation in a patient seven years post severe TBI. Baseline data were collected over 4 weeks to account for variability in status with neurobehavioral measures, including the Disorders of Consciousness scale (DOCS), Coma Near Coma scale (CNC), and Consciousness Screening Algorithm...
January 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28101804/white-matter-hyperintensities-correlate-to-cognition-and-fiber-tract-integrity-in-older-adults-with-hiv
#10
Christa Watson, Edgar Busovaca, Jessica M Foley, I Elaine Allen, Christopher G Schwarz, Neda Jahanshad, Talia M Nir, Pardis Esmaeili-Firidouni, Benedetta Milanini, Howard Rosen, Owen T Carmichael, Paul M Thompson, Victor G Valcour
Our aim was to examine the clinical relevance of white matter hyperintensities (WMH) in HIV. We used an automated approach to quantify WMH volume in HIV seropositive (HIV+; n = 65) and HIV seronegative (HIV-; n = 29) adults over age 60. We compared WMH volumes between HIV+ and HIV- groups in cross-sectional and multiple time-point analyses. We also assessed correlations between WMH volumes and cardiovascular, HIV severity, cognitive scores, and diffusion tensor imaging variables. Serostatus groups did not differ in WMH volume, but HIV+ participants had less cerebral white matter (mean: 470...
January 18, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28101762/neuropsychological-assessment-in-migraine-patients-a-descriptive-review-on-cognitive-implications
#11
REVIEW
Maria Foti, Viviana Lo Buono, Francesco Corallo, Rosanna Palmeri, Placido Bramanti, Silvia Marino
Migraine is considered a disabling disorder with highly prevalence in population. Recent studies report that migraine patients have a cognitive decline associated to structural brain alterations. We search on PubMed and Web of Science databases and screening references of included studies and review articles for additional citations. From 519 studies identified, only 16 met the inclusion criteria. All studies were conducted on 1479 migraineurs (190 non-migraine headache and 11,978 controls subject) and examined the association between migraine and cognitive impairment...
January 18, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28101729/air-pollution-and-successful-aging-recent-evidence-and-new-perspectives
#12
REVIEW
Gali Cohen, Yariv Gerber
PURPOSE OF REVIEW: Worldwide demographic changes occurring in a relatively short period have led to a growing interest in the determinants of aging "successfully" and how to promote a healthier old age. As environmental exposures such as ambient air pollution are believed to play a role in the process of aging, they might represent one of the pathways turning potential successful agers to unsuccessful agers. We aimed to critically review the current epidemiological evidence of the associations between chronic exposure to ambient air pollution and several key determinants of unsuccessful aging and to identify specific populations of unsuccessful agers that are potentially more vulnerable to air pollution's health effects...
January 18, 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/28101695/the-spatial-release-of-cognitive-load-in-cocktail-party-is-determined-by-the-relative-levels-of-the-talkers
#13
Guillaume Andéol, Clara Suied, Sébastien Scannella, Frédéric Dehais
In a multi-talker situation, spatial separation between talkers reduces cognitive processing load: this is the "spatial release of cognitive load". The present study investigated the role played by the relative levels of the talkers on this spatial release of cognitive load. During the experiment, participants had to report the speech emitted by a target talker in the presence of a concurrent masker talker. The spatial separation (0° and 120° angular distance in azimuth) and the relative levels of the talkers (adverse, intermediate, and favorable target-to-masker ratio) were manipulated...
January 18, 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/28101665/feasibility-and-psychometric-properties-of-the-adjusted-dswal-qol-questionnaire-for-dysphagic-patients-with-additional-language-and-or-cognitive-impairment-part-i
#14
Ingeborg S Simpelaere, Jan Vanderwegen, Kristien Wouters, Marc De Bodt, Gwen Van Nuffelen
The Swallowing Quality-of-Life questionnaire (SWAL-QoL) is considered the gold standard for assessing health-related quality of life in people with dysphagia. However, many dysphagic patients struggle to complete this questionnaire because of additional functional sequelae such as language impairment and cognitive disorders. In this study, we sought to develop an adjusted Dutch version of the SWAL-QoL (aDSWALQoL) and to evaluate its psychometric properties and feasibility compared with the original questionnaire...
January 18, 2017: Dysphagia
https://www.readbyqxmd.com/read/28101555/predictors-for-living-at-home-after-geriatric-inpatient-rehabilitation-a-prospective-cohort-study
#15
Jan Kool, Peter Oesch, Stefan Bachmann
OBJECTIVE: To evaluate patient characteristics predicting living at home after geriatric rehabilitation. DESIGN: Prospective cohort study. PATIENTS: A total of 210 patients aged 65 years or older receiving inpatient rehabilitation. METHODS: Candidate predictors evaluated during rehabilitation were: age, vulnerability (Vulnerable Elders Survey), multimorbidity (Cumulative Illness Rating Scale), cognition (Mini-Mental State Examination), depression (Hospital Anxiety and Depression Scale), living alone, previous independence in activities of daily living, fall risk, and mobility at discharge (Timed Up and Go test)...
January 18, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28101460/captopril-and-valsartan-may-improve-cognitive-function-through-potentiation-of-the-brain-antioxidant-defense-system-and-attenuation-of-oxidative-nitrosative-damage-in-stz-induced-dementia-in-rat
#16
Yasaman Arjmand Abbassi, Mohammad Taghi Mohammadi, Mahsa Sarami Foroshani, Javad Raouf Sarshoori
Purpose: Previous findings have shown the crucial roles of brain renin-angiotensin system (RAS) in pathogenesis of Alzheimer's disease (AD). Since RAS inhibitors may have beneficial effects on dementia and cognitive function in elderly people, the aim of present study was to examine the neuroprotective actions of captopril and valsartan on memory function and neuronal damage in experimental model of AD. Methods: Adult forty male Wistar rats (220-280g) were randomly divided into 5 groups; Control, Vehicle, Alzheimer and treatment groups...
December 2016: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28101151/effect-of-general-anesthesia-on-serum-%C3%AE-amyloid-protein-and-regional-cerebral-oxygen-saturation-of-elderly-patients-after-subtotal-gastrectomy
#17
Peng Yu, Hua Wang, Lei Mu, Xuemei Ding, Wei Ding
The aim of the present study was to investigate the influence of general anesthesia on serum β-amyloid protein (Aβ) and regional cerebral oxygen saturation (rSO2) of elderly patients after subtotal gastrectomy. From June, 2014 to December, 2015, among 168 patients undergoing subtotal gastrectomy, the Mini-Mental State Examination and Montreal Cognitive Assessment was administered the day prior to surgery and the second and ninth days after the operation. In addition, we administered the tests to 168 healthy adult volunteers (healthy controls) who were treated in our hospital medical center in the same period...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28101100/the-utility-of-the-mini-addenbrooke-s-cognitive-examination-as-a-screen-for-cognitive-impairment-in-elderly-patients-with-chronic-kidney-disease-and-diabetes
#18
Peter Hobson, Kamel H Rohoma, Stephen P Wong, Mick J Kumwenda
BACKGROUND/AIMS: We tested the utility of the Mini-Addenbrooke's Cognitive Examination (M-ACE) in a cohort of older adults with chronic kidney disease (CKD) and diabetes. METHOD: The M-ACE was administered to 112 CKD and diabetes patients attending a nephrology clinic. Cognitive impairment was based upon patient, informant, and case review, neuropsychological assessment, and application of criteria for mild cognitive impairment (MCI) and the Diagnostic and Statistical Manual of Mental Disorders, fifth edition for dementia...
September 2016: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/28100727/quantitative-assessment-of-white-matter-injury-in-preterm-neonates-association-with-outcomes
#19
Ting Guo, Emma G Duerden, Elysia Adams, Vann Chau, Helen M Branson, M Mallar Chakravarty, Kenneth J Poskitt, Anne Synnes, Ruth E Grunau, Steven P Miller
OBJECTIVE: To quantitatively assess white matter injury (WMI) volume and location in very preterm neonates, and to examine the association of lesion volume and location with 18-month neurodevelopmental outcomes. METHODS: Volume and location of WMI was quantified on MRI in 216 neonates (median gestational age 27.9 weeks) who had motor, cognitive, and language assessments at 18 months corrected age (CA). Neonates were scanned at 32.1 postmenstrual weeks (median) and 68 (31...
January 18, 2017: Neurology
https://www.readbyqxmd.com/read/28100212/the-effects-of-breakfast-on-short-term-cognitive-function-among-chinese-white-collar-workers-protocol-for-a-three-phase-crossover-study
#20
Zhenchuang Tang, Na Zhang, Ailing Liu, Dechun Luan, Yong Zhao, Chao Song, Guansheng Ma
BACKGROUND: As the first meal of the day, breakfast plays an important role in supplying energy and nutrients, which are critical to working and learning activities. A three-phase crossover study was designed to investigate the effects of breakfast on cognitive function among Chinese white-collar workers. The planned study protocol is presented. METHODS: A total of 264 participants aged 25-45 years will be recruited from Shenyang and Chongqing. Self-administered questionnaires will be used to collect information on age, gender, marital status, education level, occupation, smoking habits, drinking habits, and breakfast behaviours...
January 18, 2017: BMC Public Health
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