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histoplasmosis

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https://www.readbyqxmd.com/read/28736209/histoplasmosis-presenting-as-laryngeal-ulcer-in-a-post-renal-transplant-male-an-unusual-case-from-india
#1
P M Jawale, H V Gulwani
Histoplasmosis has variable clinical presentation that mimics various benign and malignant lesions. It is more often associated with pulmonary lesions and disseminated form of disease. Herein, we report a rare case of localized laryngeal histoplasmosis in a 62-year-old Indian man who presented with hoarseness of voice and dysphagia. Post-renal transplant, he was on immunosuppressive drugs for last three years. Laryngoscopy revealed an ulceroproliferative growth at base of tongue, which was extending upto the pyriform fossa...
July 20, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28725444/post-tuberculous-fibrosing-mediastinitis-a-review-of-the-literature
#2
REVIEW
Zhe Wu, Hannah Jarvis, Luke S Howard, Corrina Wright, Onn Min Kon
Fibrosing mediastinitis (FM) is a rare disease where there is thickening of the fibrous tissue in the mediastinum. While histoplasmosis is the the most common recognised cause, the link with tuberculosis (TB) has been rarely documented. We review the link between TB and FM, and describe a case of probable TB-related FM.Our case is of a 74-year-old man who presented with breathlessness 3 years after fully treated TB. Scans revealed a calcified soft tissue mass within the mediastinum, and a diagnosis of fibrosing mediastinitis resulting in pulmonary hypertension was made...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28719316/high-mortality-and-coinfection-in-a-prospective-cohort-of-human-immunodeficiency-virus-acquired-immune-deficiency-syndrome-patients-with-histoplasmosis-in-guatemala
#3
Blanca Samayoa, Monika Roy, Angela Ahlquist Cleveland, Narda Medina, Dalia Lau-Bonilla, Christina M Scheel, Beatriz L Gomez, Tom Chiller, Eduardo Arathoon
Histoplasmosis is one of the most common and deadly opportunistic infections among persons living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome in Latin America, but due to limited diagnostic capacity in this region, few data on the burden and clinical characteristics of this disease exist. Between 2005 and 2009, we enrolled patients ≥ 18 years of age with suspected histoplasmosis at a hospital-based HIV clinic in Guatemala City. A case of suspected histoplasmosis was defined as a person presenting with at least three of five clinical or radiologic criteria...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28717672/coccidioidomycosis-a-cause-of-sarcoidosis
#4
Tim Kuberski, Isaac Yourison
BACKGROUND: Sarcoidosis is a granulomatous disease of unknown etiology and coccidioidomycosis is a granulomatous fungal infection endemic to the southwestern United States. Clinical observations on patients with sarcoidosis and coccidioidomycosis simultaneously led to the hypothesis that sarcoidosis can be caused by the fungus Coccidioides. METHODS: Two patients with sarcoidosis and coccidioidomycosis were studied, one prospectively (ie, a patient with sarcoidosis was predicted to develop coccidioidomycosis) and the other retrospectively (ie, a patient with coccidioidomycosis develops sarcoidosis)...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28710196/disseminated-histoplasmosis-presenting-as-multiple-oral-ulcers
#5
Nicholas Hendren, Christina Yek, Jason Mull, James B Cutrell
A 61-year-old female with a history of advanced HIV disease and chronic hepatitis B was presented with an 8-week history of painful oral ulcers. She appeared systemically well but examination revealed multiple well-demarcated clean-based ulcers on the tongue and hard palate. Biopsy of one of the lesions showed numerous histiocytes containing intracellular yeast forms consistent with Histoplasma capsulatum var. capsulatum Fungal blood cultures subsequently grew H. capsulatum var. capsulatum, confirming a diagnosis of disseminated histoplasmosis...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28702025/cellular-and-molecular-defects-underlying-invasive-fungal-infections-revelations-from-endemic-mycoses
#6
REVIEW
Pamela P Lee, Yu-Lung Lau
The global burden of fungal diseases has been increasing, as a result of the expanding number of susceptible individuals including people living with human immunodeficiency virus (HIV), hematopoietic stem cell or organ transplant recipients, patients with malignancies or immunological conditions receiving immunosuppressive treatment, premature neonates, and the elderly. Opportunistic fungal pathogens such as Aspergillus, Candida, Cryptococcus, Rhizopus, and Pneumocystis jiroveci are distributed worldwide and constitute the majority of invasive fungal infections (IFIs)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28701830/role-of-fine-needle-aspiration-cytology-in-diagnosis-of-disseminated-histoplasmosis-in-an-immunocompetent-patient-a-case-report
#7
Sagarika Samantaray, Sasmita Panda, Sashibhusan Dash, Niranjan Rout
Histoplasmosis is a mycotic infection caused by dimorphic fungus, Histoplasma capsulatum. The organisms are usually found within the cells (macrophages). This organism mostly affects lungs in immunocompetent individuals and disseminated forms are seen in immunocompromised cases. Here, we describe a case of disseminated histoplasmosis in an immunocompetent, 35-year-old female with lymphadenopathy diagnosed by fine-needle aspiration cytology and cell block.
July 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28698842/hemophagocytic-lymphohistiocytosis-secondary-to-histoplasmosis
#8
B K Karthik Bommanan, Shano Naseem, Neelam Varma
No abstract text is available yet for this article.
June 2017: Blood Research
https://www.readbyqxmd.com/read/28698787/peripheral-t-cell-lymphoma-in-mediastinum-lymph-nodes-and-lung-associated-to-histoplasmosis-in-a-patient-with-chronic-lymphoid-leukemia-small-lymphocytic-lymphoma
#9
Cristiano Claudino Oliveira
No abstract text is available yet for this article.
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/28690073/demonstrating-hickam-s-dictum-metachronous-pulmonary-adenocarcinoma-carcinoid-tumor-and-histoplasmosis
#10
Bradley Icard, Frank Biscardi, Umar Sofi
No abstract text is available yet for this article.
July 6, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28687695/hiding-in-plain-sight-a-case-of-chronic-disseminated-histoplasmosis-with-central-nervous-system-involvement
#11
Guramrinder Singh Thind, Sandeep Patri
A 64-year-old man presented with gradual onset of confusion, ataxia and 25-pound weight loss over 3 months. MRI of the brain revealed two enhancing cerebellar lesions suspicious for metastases. Positron emission tomography-CT showed enhancement of cervical and axillary lymph nodes. Left axillary lymph node biopsy showed no evidence of malignancy but instead showed fungal organisms morphologically consistent with Histoplasma spp. Disseminated histoplasmosis with central nervous system involvement was suspected...
July 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28677260/correlation-of-cd4-counts-with-clinical-and-histopathological-findings-in-disseminated-histoplasmosis-a-10-year-retrospective-study
#12
Sondang P Sirait, Kusmarinah Bramono, Nathalia Hermanto
BACKGROUND: Disseminated cutaneous histoplasmosis (DCH) is one of the manifestations of systemic histoplasmosis infection in HIV-positive patients. Interaction between host immune status and histoplasmosis infection is still poorly understood. It is thought that immune status, represented by CD4 counts, may be correlated with clinical and histopathological findings. OBJECTIVE: To correlate the CD4 counts with the different clinical and histopathological findings in cutaneous histoplasmosis...
July 5, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28652964/a-necrotic-tonsillar-lesion-an-unusual-presentation-of-disseminated-histoplasmosis
#13
Christopher Keen, Hwajeong Lee, Lisa Galati, John Fantauzzi, Richard Blinkhorn, Timothy A Jennings, Sudha Chaturvedi, Marc A Judson
We report a case of tonsillar histoplasmosis with hematogenous dissemination in a woman receiving infliximab for Crohn's disease. She also had a history of sarcoidosis. Due to the unusual location and confounding medical history, our case provided a diagnostic dilemma. Histoplasma infection was confirmed histologically, and the patient responded well to appropriate treatment.
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28647712/disseminated-histoplasmosis-in-a-patient-with-hiv-diagnosed-by-simple-bedside-investigations
#14
Pongsakorn Buraphat, Wannarat Pongpirul, Patama Suttha
No abstract text is available yet for this article.
June 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28626627/tonsillar-ulceration-as-manifestation-of-disseminated-african-histoplasmosis-in-an-immunocompetent-portuguese-host
#15
L Cardoso, C Silva, N Marques, C Veríssimo
Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum. Rare in Europe but endemic in some regions of Brazil, United States, Africa and Asia. Most of the cases are asymptomatic. Disseminated form is defined by the presence of an extra-pulmonary focus, particularly associated with immunosuppression. We report a case of an unilateral persisted tonsillar ulceration, in an immunocompetent Portuguese host, as manifestation of disseminated African histoplasmosis 45 years later after living 3 years in Africa...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28617878/granulomatous-hepatitis-a-rare-primary-manifestation-of-disseminated-histoplasmosis-in-a-renal-transplant-recipient
#16
Jiten P Kothadia, Vyshnavi Kone, Shah Giashuddin
No abstract text is available yet for this article.
June 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28616380/rare-case-of-pulmonary-histoplasmosis-complicated-with-bronchocentric-granulomatosis-in-a-non-endemic-area
#17
Evanthia Botsa, Ioanna Thanou, Stamatina Kabanarou, Loukas Thanos
BACKGROUND: Pulmonary histoplasmosis is a fungal infection caused by histoplasma capsulatum, rarely diagnosed in non endemic areas and/or immunocompromised patients. Complication of pulmonary histoplasmosis with bronchocentric granulomatosis is extremely rare. CASE REPORT: A 48-year-old man with prolonged fever and nausea was admitted to our hospital. Clinical examination revealed pathological auscultatory sounds to the left lung. Computed tomography was performed and revealed a large solid mass of the left upper lobe, limited pleural and pericardial effusion and calcified lymphadenopathy of mediastinum...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28606017/histoplasmosis-mimicking-metastatic-spinal-tumour
#18
Bing Liu, Liyan Qu, Jian Zhu, Zhengming Yang, Shigui Yan
Histoplasmosis is an infection caused by a fungus called Histoplasma. Diagnosis of histoplasmosis is based on the culture of biological samples and detection of fungus in tissues. Histoplasmosis can mimic malignant lesions. We report a 65-year-old, immunocompetent, male patient with back pain. We describe the main clinical and radiological characteristics in our patient who had vertebral histoplasmosis that mimicked cancer. A computed tomography scan showed lytic lesions of the right side of T4, T5, and T6 vertebral bodies...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28602386/respiratory-infections-associated-with-anti-tnf%C3%AE-agents
#19
REVIEW
E Blanchard, M-E Truchetet, I Machelart, J Séneschal, C Raherison-Semjen
Anti-TNFα agents have proved effective in the treatment of various inflammatory, rheumatologic, dermatologic, and gastrointestinal diseases. Severe respiratory tract infections of bacterial or fungal origin have emerged as important complications in patients receiving such treatments. The risk of infection due to anti-TNFα therapy is difficult to assess in these patients who are immunocompromised because of the underlying disease itself and of previous or concomitant immunosuppressive drugs. This excessive infection risk seems real, particularly in the first six months following treatment initiation, and higher for patients receiving anti-TNFα monoclonal antibodies than for those receiving soluble TNFα receptor...
June 8, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28554708/protothecosis-in-a-patient-with-t-cell-lymphocytic-leukemia
#20
Mariana S Fernández, Florencia D Rojas, María E Cattana, Javier E Mussin, María de Los Ángeles Sosa, Carlos D Benzoni, Gustavo E Giusiano
Human protothecosis is a rare infection caused by algae of the genus Prototheca. Prototheca wickerhamii has been recognized as the main species that causes infection in immunocompromised hosts with deficits in innate or cellular immunity. We report a case of persisting subcutaneous protothecosis in a patient with T-cell large granular lymphocyte leukemia, who also presented a history of disseminated histoplasmosis.
May 27, 2017: Revista Argentina de Microbiología
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