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Quo vadis

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https://www.readbyqxmd.com/read/29226585/block-copolymer-self-assembly-in-solution-quo-vadis
#1
Felix Helmut Schacher, Johannes Brendel
The desire for increasing complexity while maintaining control over every aspect of the process itself - this might be used as a provocative description of the developments in block copolymer self-assembly in solution over the last decade. The community has witnessed tremendous progress, not only with regard to the design of building blocks, but also in terms of understanding assembly pathways, interfacial properties, or kinetic obstacles. In particular, the latter can be of interest (and actually turned into an advantage), if structures are targeted, which are not in thermodynamic equilibrium...
December 11, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/29212333/-quo-vadis-diabetes-technology
#2
George Grunberger
Management of patients with diabetes mellitus who require intensive insulin therapy has changed dramatically. From urine and then whole blood glucose monitoring patients can now wear personal continuous glucose monitors; from using multiple insulin injections they can now deliver subcutaneous insulin continuously using ever-more sophisticated insulin pumps. With the current integration of continuous glucose monitoring and insulin pumps a new era is arriving when "smart" insulin pumps can automate insulin delivery to assure more stable glycemic control while minimizing episodes of hypoglycemia...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29212332/quo-vadis-diabetes-technology
#3
George Grunberger
Management of patients with diabetes mellitus who require intensive insulin therapy has changed dramatically. From urine and then whole blood glucose monitoring patients can now wear personal continuous glucose monitors; from using multiple insulin injections they can now deliver subcutaneous insulin continuously using ever-more sophisticated insulin pumps. With the current integration of continuous glucose monitoring and insulin pumps a new era is arriving when "smart" insulin pumps can automate insulin delivery to assure more stable glycemic control while minimizing episodes of hypoglycemia...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29169475/outcomes-in-pediatric-dilated%C3%A2-cardiomyopathy-quo-vadis
#4
EDITORIAL
Robert G Weintraub, Peta M A Alexander
No abstract text is available yet for this article.
November 28, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29079546/congenital-disorders-of-glycosylation-cdg-quo-vadis
#5
REVIEW
Romain Péanne, Pascale de Lonlay, François Foulquier, Uwe Kornak, Dirk J Lefeber, Eva Morava, Belén Pérez, Nathalie Seta, Christian Thiel, Emile Van Schaftingen, Gert Matthijs, Jaak Jaeken
The survey summarizes in its first part the current status of knowledge on the Congenital Disorders of Glycosylation (CDG) with regard to their phenotypic spectrum, diagnostic and therapeutic strategies, and pathophysiology. It documents the clinical and basic research activities, and efforts to involve patients and their families. In the second part, it tries to look into the future of CDG. More specific biomarkers are needed for fast CDG diagnosis and treatment monitoring. Whole genome sequencing will play an increasingly important role in the molecular diagnosis of unsolved CDG...
October 24, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29045164/ehealth-literacy-research-quo-vadis
#6
Lena Griebel, Heidi Enwald, Heidi Gilstad, Anna-Lena Pohl, Julia Moreland, Martin Sedlmayr
The concept of electronic health (eHealth) literacy evolved from the social and information sciences and describes competencies necessary to use electronic health services. As it is a rather new topic, and as there is no current overview of the state of the art in research, it is not possible to identify research gaps. Therefore, the objective of this viewpoint article is to increase knowledge on the current state of the art of research in eHealth literacy and to identify gaps in scientific research which should be focused on by the research community in the future...
October 18, 2017: Informatics for Health & Social Care
https://www.readbyqxmd.com/read/28958605/quo-vadis-probiotics-human-research-supports-further-study-of-beneficial-microbes-in-mental-health
#7
Martin A Katzman, Alan C Logan
No abstract text is available yet for this article.
October 2017: EBioMedicine
https://www.readbyqxmd.com/read/28952620/organoactinides-in-catalytic-transformations-scope-mechanisms-and-quo-vadis
#8
Heng Liu, Tapas Ghatak, Moris S Eisen
The last decade has witnessed wonderful and remarkable advances in the chemistry of early actinides, providing information on not only the reactivity of these types of compounds in stoichiometric reactions but also their utilization in challenging catalytic processes. This canvas of knowledge allows the design of chemical reactivities to reach a high level of sophistication. As compared to early/late transition metal and lanthanide complexes, the actinides display complementary and in some cases real unique performances for similar organic transformations...
October 12, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28877448/gene-therapy-for-heart-failure-status-quo-and-quo-vadis
#9
Olympia Bikou, Kiyotake Ishikawa
Gene therapy is recently attracting increased attention and cardiac gene therapy is not an exception. Advances in gene transfer vectors, development of new vector delivery methods, and discovery of new gene targets continue to fuel our motivation to use this approach in routine bedside care. In the past two years, we have witnessed important advances in the field, as the results of three recently completed cardiac gene therapy programs have been published. Unfortunately, none of the trials have met their primary efficacy endpoints, but sub-analysis demonstrated potential efficacy...
June 2017: Discovery Medicine
https://www.readbyqxmd.com/read/28841747/-psychotherapy-quo-vadis
#10
Gunther Meinlschmidt, Marion Tegethoff
Background: The science and practice of psychotherapy is continuously developing. The goal of this article is to describe new impulses, guiding current advancements in the field. Methods: This paper provides a selective narrative review, synthesizing and condensing relevant literature identified through various sources, including MEDLINE, EMBASE, PsycINFO, and "Web of Science", as well as citation tracking, to elaborate key developments in the field of psychotherapy Results: We describe several dynamics: 1) Following up the so-called "third wave of cognitive behavioral therapy", new interventions arise that have at their core fostering interpersonal virtues, such as compassion, forgiveness, and gratitude; 2) Based on technological quantum leaps, new interventions arise that exploit current developments in the field of new media, information, and communication technologies, as well as brain imaging, such as digital interventions for mental disorders and new forms of neurofeedback; 3) Inspired by the field of positive psychology, there is a revival of the promotion of strength and resilience in therapeutic contexts; 4) In light of the new paradigm "precision medicine", the issue of differential and adaptive indication of psychotherapy, addressed with new methods, regains relevance and drives a new field of "precision psychotherapy"...
August 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/28770213/positron-emission-tomography-determined-hyperemic-flow-myocardial-flow-reserve-and-flow-gradient-quo-vadis
#11
REVIEW
Thorsten M Leucker, Ines Valenta, Thomas Hellmut Schindler
Positron emission tomography/computed tomography (PET/CT) applied with positron-emitting flow tracers such as (13)N-ammonia and (82)Rubidium enables the quantification of both myocardial perfusion and myocardial blood flow (MBF) in milliliters per gram per minute for coronary artery disease (CAD) detection and characterization. The detection of a regional myocardial perfusion defect during vasomotor stress commonly identifies the culprit lesion or most severe epicardial narrowing, whereas adding regional hyperemic MBFs, myocardial flow reserve (MFR), and/or longitudinal flow decrease may also signify less severe but flow-limiting stenosis in multivessel CAD...
2017: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28758406/meningioma-research-status-quo-and-quo-vadis
#12
Matthias Preusser, Priscilla Brastianos, Helen A Shih
No abstract text is available yet for this article.
July 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28758298/quo-vadis-what-is-the-future-of-periodontics-how-will-we-get-there
#13
REVIEW
Kenneth S Kornman, William V Giannobile, Gordon W Duff
Approximately 40 years ago periodontists began systematically developing the evidence to treat predictably and prevent gingivitis and periodontitis. More recently, periodontists have been among a small group of skilled dental-implant surgeons leading that revolution in dentistry. Today, much of the mild/localized moderate periodontitis is not treated by periodontists, and an increasing number of implants are placed by dentists with limited surgical training. The current field of periodontics includes a broad range of surgical skills and technologies to regenerate predictably destroyed tissues and manage complex interdisciplinary treatment that may, in some way, involve the tissues that support teeth and implants...
October 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28753439/quo-vadis-tracing-the-fate-of-neural-crest-cells
#14
REVIEW
Luis Zurkirchen, Lukas Sommer
The neural crest is a transient structure in vertebrate embryos that produces migratory cells with an astonishing developmental potential. While neural crest fate maps have originally been established through interspecies transplantation assays, dye labeling, and retroviral infection, more recent methods rely on approaches involving transgenesis and genome editing. These technologies allowed the identification of minor neural crest-derived cell populations in tissues of non-neural crest origin. Furthermore, in vivo multipotency at the single cell level and stage-dependent fate acquisitions were demonstrated using genetic technologies...
July 25, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28753307/coumarin-versus-chromone-monoamine-oxidase-b-inhibitors-quo-vadis
#15
André Fonseca, Joana Reis, Tiago Silva, Maria João Matos, Donatella Bagetta, Francesco Ortuso, Stefano Alcaro, Eugenio Uriarte, Fernanda Borges
Because of the lack of significant disease-modifying drugs for neurodegenerative disorders, a pressing need for new chemical entities endowed with IMAO-B still exists. Within this framework, and for the first time, a study was performed to compare coumarin- and chomone-3-phenylcarboxamide scaffolds. Compounds 10a and 10b were the most potent, selective, and reversible noncompetitive IMAO-B. The benzopyrone sp(2) oxygen atom was found to be position independent and a productive contributor for the ligand-enzyme complex stability...
August 24, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28707192/-geriatrics-or-geriatricization-of-medicine-quo-vadis-geriatrics
#16
REVIEW
G F Kolb
This article examines the question whether and how geriatrics will change in the future and whether in view of the demographic changes the trend will go more in the direction of a further expansion of geriatrics or more towards a geriatricization of individual specialist medical fields. The different development of geriatrics in the individual Federal States can only be understood historically and is absolutely problematic against the background of the new hospital remuneration system. Geriatrics is a typical cross-sectional faculty and still has demarcation problems with other faculties but has also not yet clearly defined the core competence...
December 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28648474/combining-left-ventricular-volume-reduction-techniques-with-cell-therapies-quo-vadis
#17
EDITORIAL
Stavros G Drakos
No abstract text is available yet for this article.
March 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28643703/ophthalmology-residency-training-in-india-quo-vadis
#18
EDITORIAL
Santosh G Honavar
No abstract text is available yet for this article.
June 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28561236/-quo-vadis-dgpr%C3%A3-c-associated-members-goals-for-the-future
#19
Jonas Kolbenschlag, Felix Paprottka, Juri Wagner, Ole Goertz, Jutta Liebau, Adrien Daigeler, Raymund E Horch, Marcus Lehnhardt
Plastic surgery is extremely diverse and offers various fields of work. To provide optimal support for plastic surgeons in training, it is therefore paramount to know their mid- and long-term goals. To that end, we conducted a web-based survey among the 462 associated members of the German Association of Plastic, Reconstructive and Aesthetic Surgeons (DGPRÄC). Besides asking questions about the current status, we specifically inquired about the pursued setting and main area of work. 84 completed questionnaires were evaluated...
September 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28558237/meeting-proceedings-2017-cornell-university-baker-symposium-quo-vadis-the-boundless-trajectories-of-chemical-biology
#20
Jeremy M Baskin, Yimon Aye
No abstract text is available yet for this article.
June 13, 2017: Biochemistry
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