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https://www.readbyqxmd.com/read/29754808/long-term-event-reduction-after-left-atrial-appendage-closure-results-of-the-iberian-registry-ii
#1
José R López-Mínguez, Juan M Nogales-Asensio, Eduardo Infante De Oliveira, Vasco De Gama Ribeiro, Rafael Ruiz-Salmerón, Dabit Arzamendi-Aizpurua, Marco Costa, Hipólito Gutiérrez-García, José Antonio Fernández-Díaz, Victoria Martín-Yuste, Juan Carlos Rama-Merchán, Raúl Moreno-Gómez, Amparo Benedicto-Buendía, Andrés Íñiguez-Romo
INTRODUCTION AND OBJECTIVES: Many patients with nonvalvular atrial fibrillation are still left without protection due to a contraindication for anticoagulants. This study aimed to establish the occurrence of stroke and major bleeding events in patients with nonvalvular atrial fibrillation and left atrial appendage closure with long-term follow-up and to explore the factors associated with higher long-term mortality. METHODS: Analysis of a multicenter single cohort prospectively recruited from 2009 to 2015...
May 10, 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29701378/amniotic-membrane-in-the-treatment-of-varicose-ulcers-a-center-experience
#2
J Rocha-Neves, André Ferreria, Joel Sousa, Marina Dias-Neto, Luis Gamas, Isabel Vilaça, José Teixeira
INTRODUCTION: Amniotic membrane (AM) is an option as a cover in varicose leg ulcers, promoting epithelization. Anti-inflammatory and analgesic proprieties are described, as well as high levels of growth factors and angiogenesis. The costs are inferior to surgical plasty. The aim of this work is to describe the results of AM in the treatment of varicous leg ulcers in a group of patients refractory to the best medical treatment. METHODS: A pilot prospective trial was conducted...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29617484/-trends-and-factors-associated-with-food-insecurity-in-brazil-the-national-household-sample-survey-2004-2009-and-2013
#3
Taíse Gama Dos Santos, Jonas Augusto Cardoso da Silveira, Giovana Longo-Silva, Elyssia Karine Nunes Mendonça Ramires, Risia Cristina Egito de Menezes
The aim of this study was to analyze trends and factors associated with food insecurity in Brazil in 2004, 2009, and 2013, using microdata from the National Household Sample Survey (PNAD). Food insecurity was assessed using the Brazilian Food Insecurity Scale. Independent variables were selected from a conceptual model of determination of food insecurity, which was also used in the elaboration of multiple generalized linear models. The results show a downward trend in food insecurity prevalence from 2004 to 2013, especially for moderate and severe food insecurity, from 17% in 2004 (95%CI: 15...
March 29, 2018: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29605628/exploring-different-photodynamic-therapy-parameters-to-optimize-elimination-of-enterococcus-faecalis-planktonic-forms
#4
Janir Alves Soares, Suelleng Maria Cunha Santos Soares, Rudys Rodolfo de Jesus Tavarez, Claudia de Castro Rizzi, Silvana Cristina Gama Vaz Rodrigues, Etevaldo Matos Maia Filho, Manoel Brito-Júnior, Rodrigo Dantas Pereira, Paula Prazeres Magalhães, Luiz de Macêdo Farias
BACKGROUND: The failure of endodontic treatment is linked to the presence of Enterococcus faecalis in the root canals. The scope of study was to evaluate the influence of the energy dose and frequency of photodynamic therapy (PDT cycles), as well as the volume of bacterial suspensions (BS) in the elimination of Enterococcus faecalis planktonic forms. METHODS: In four successive assays BS of Enterococcus faecalis ATCC 19433 were irradiated with a diode laser (40 mW) using the photosensitizer (PS) methylene blue (MB) (0...
March 29, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29452815/variable-versus-conventional-lung-protective-mechanical-ventilation-during-open-abdominal-surgery-provar-a-randomised-controlled-trial
#5
P M Spieth, A Güldner, C Uhlig, T Bluth, T Kiss, C Conrad, K Bischlager, A Braune, R Huhle, A Insorsi, F Tarantino, L Ball, M J Schultz, N Abolmaali, T Koch, P Pelosi, M Gama de Abreu
BACKGROUND: Experimental studies showed that controlled variable ventilation (CVV) yielded better pulmonary function compared to non-variable ventilation (CNV) in injured lungs. We hypothesized that CVV improves intraoperative and postoperative respiratory function in patients undergoing open abdominal surgery. METHODS: Fifty patients planned for open abdominal surgery lasting >3 h were randomly assigned to receive either CVV or CNV. Mean tidal volumes and PEEP were set at 8 ml kg-1 (predicted body weight) and 5 cm H2 O, respectively...
March 2018: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28590831/effects-of-testosterone-administration-on-liver-structure-and-function-in-aging-rats
#6
Ricardo Aparecido Baptista Nucci, Ana Caroline de Souza Teodoro, Walter Krause Neto, Wellington de Assis Silva, Romeu Rodrigues de Souza, Carlos Alberto Anaruma, Eliane Florencio Gama
Aging males have a decrease in testosterone levels, by which the testosterone treatment may influence in a negatively fashion the liver. AIM: This study aimed to analyze the effects of aging with or without testosterone administration on the liver components of animals. METHODS: Wistar rats were divided into three groups: 20 months' group (G20), 24 months' group (G24), group treated with testosterone for 16 weeks (GT). All groups were sacrificed at 24 months except for G20 that was sacrificed at 20 months...
June 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/26165047/relationship-of-hepatotoxicity-and-the-target-tissue-dose-of-decabrominated-diphenyl-ether-in-subacutely-exposed-wistar-rats
#7
Marijana Ćurčić, Sladjana Tanasković, Sanja Stanković, Saša Janković, Marko Antunović, Snežana Djordjević, Vesna Kilibarda, Slavica Vučnić, Biljana Antonijević
BACKGROUND/AIM: Based on numerous studies in animals, the most prominent toxic effects of decabrominated diphenyl ether (BDE-209) are observed in the liver, thyroid hormone homeostasis, reproductive and nervous systems. BDE-209 exhibits its toxic effects partly through the aryl hydrocarbon (Ah) receptor and consequent induction of hepatic microsomal enzymes. The aim of this study was to assess the hepatotoxic effect vs target tissue dose of BDE-209 in the subacutely orally exposed Wistar rats...
May 2015: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
https://www.readbyqxmd.com/read/21594376/identification-of-exons-in-a-novel-embryonal-carcinoma-locus-using-the-grail-program
#8
R Gama, Y Du, J Bauman, P McCormick
Embryonal carcinoma (EC) cells have proven to be of particular value in studies of both oncogenesis and mammalian development, as well as in evaluating the relationship between these two phenomena. Infection of the EC cell line, NR1-0, with a defective retrovirus containing a neomycin resistance cassette (Neo(r)), produced a mutant cell line: NR1-6. Genetic analysis of this variant cell line indicates that there is only a single insertion site. Interestingly, however, the NR1-6 cell line is unique in its morphology, tumorigenicity, and differentiative potential (1)...
March 1996: Oncology Reports
https://www.readbyqxmd.com/read/21594338/novel-mouse-repetitive-element-structures-in-an-embryonal-carcinoma-mutant-cell-line
#9
R Gama, Y Du, J Bauman, T Chan, P McCormick
A mutant embryonal carcinoma (EC) cell line, NR1-6, has been isolated subsequent to infection with a retroviral insert containing a neomycin resistance cassette (Neo(r)) (1). This variant cell line has only a single insertion site, but is unique in its morphology, tumorigenicity, and differentiative potential (2). In order to understand the exact nature of the mutational event, we have sequenced the regions immediately flanking the insertion site (encompassing over 18 kb). Searches for homology in GenBank using the GCG and Blast programs have revealed homology to only a few small conserved regions (4 B1 repetitive elements approximately 150 bp long and a CA/GT dinucleotide repeat)...
January 1996: Oncology Reports
https://www.readbyqxmd.com/read/17974439/-biochemistry-in-liver-cancer
#10
N Kostić, J Dzelebdzić, D Miljković, Z Isajlović
In a group of patients (n=18) with primary (n=7) liver cancer high increase in enzyme activities (AST, ALT, AP, gama-GT, 5'NU), billirubin, alpha-1 AT, alpha- and beta-globulins and alpha-phetoprotein, and considerable decrease of albumin and cholinesterase, were established. These disturbances were duo to the weakened biofunction of the liver. All the examined biochemical parameters are of great significance in the differential diagnosis of cancer, prognosis and development of the disease.
September 1995: Srpski Arhiv za Celokupno Lekarstvo
https://www.readbyqxmd.com/read/17625661/obstructive-jaundice-induces-early-depression-of-mitochondrial-respiration-in-rat-hepatocytes
#11
Riad Naim Younes, Renato Sergio Poggetti, Belchor Fontes, Mario Matsuo Itinoshe, Vanda Mitie Yoshida, Maria Elisa A Carvalho, Dario Birolini
INTRODUCTION: Oxidative phosphorylation dysfunction of hepatocyte mitochondria is involved in the pathophysiology of organ dysfunction following obstructive jaundice (OJ). However the time period from biliary occlusion to the occurrence of the dysfunction has not been determined decisively. PURPOSE: To evaluate the early effects (1 d and 7 d) of OJ on liver mitochondria respiratory function in rats. METHODS: Male Wistar rats (200-250 g) were randomly divided into the following 3 groups: laparotomy plus OJ for 24 h (1d group) (n = 10); laparotomy plus OJ for 7 d (7d group) (n = 10); sham control procedure (CTR group) (n = 12)...
July 2007: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/11230964/amniocentesis-and-biochemical-evaluation-of-amniotic-fluid-in-ewes-at-70-100-and-145-days-of-pregnancy
#12
N C. Prestes, M C.L. Chalhoub, M D. Lopes, R K. Takahira
The objectives of this study were to determine the technical viability of amniocentesis in sheep and to observe biochemical changes in the amniotic fluid components. Amniotic fluid samples were collected by puncture in the greatest curvature of the uterine horn at days 70, 100, and 145 of pregnancy. The surgical procedure for collection of amniotic fluid samples was safe and efficient. For three stages of pregnancy, the following results were obtained: pH values 8.36, 7.34 and 7.37; glucose concentrations, 16...
March 2001: Small Ruminant Research: the Journal of the International Goat Association
https://www.readbyqxmd.com/read/9005696/-prevalence-of-chronic-hepatic-disease-in-portugal-apropos-of-a-review-carried-out-in-a-hepatology-unit
#13
A I Valente, A Almeida, A Gouveia, F Serejo, F Ramalho, A Baptista, A Saragoça, M C Moura
UNLABELLED: The chronic elevation of Aminotransferases is one of the most frequent indications for percutaneous Liver Biopsy (LB). From a retrospective study of LB performed in the Hepatology liver Unit of Santa Maria Hospital, between 1989 and 1993, we correlated the histologic diagnosis with the etiology of liver disease, sex, age and the Aspartate aminotransferase/Alanine aminotransferase (AST/ALT) and Gama-Glutamyl transpeptidase (gamma GT) index in patients with chronic liver test abnormalities...
July 1996: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/2618802/-alcoholism-in-an-industrial-population-diagnosis-prevalence-and-conditioning-factors
#14
P Fidalgo, M P Alves, A Freire, F Batista, A Fernandes, B Gard, F B Barros, J P Correia
The pattern of alcohol consumption has been studied among 92 males, workers in a factory of the Lisbon area. In this population there were three groups of ethanol consumers: I--non consumers, 6%; II--medium, up to 80g/day, 68%; III--heavy consumers, more than 80g/day, 26%. Another group (IV) was considered, for reference, with 23 patients with heavy alcoholism in the outpatients of an alcoholic addicts clinic. Besides the clinical questionnaire and medical examination, the following methods have been used and analysed: brief MAST; Le Gô, Mean Corpuscular Volume (MCV), serum glutamic oxalacetic Trasaminase (SGOT), and gama-glutamyl transpepticlase (gamma GT)...
March 1989: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/1350699/-gamma-glutamyltransferase-and-alcoholic-hepatic-disease
#15
COMPARATIVE STUDY
P Andrade, M L Rocha, C Sofia, M L Pragana, M R Oliveira, F Portela, G Monteiro
Accepting the principle that Gama-gt values are elevated in alcoholic patients, the authors attempted to find out if that enzyme might be helpful in distinguishing alcoholics with or without hepatic morphologic lesion. 110 alcoholic patients with and 57 without histologically proved hepatic lesion were studied. The authors conclude that a single determination of Gama-gt lacks specificity to detect, among the alcoholic individuals, those who already carry a morphologic, nonreversible lesion.
March 1992: Acta Médica Portuguesa
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