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Primum non nocere

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https://www.readbyqxmd.com/read/28537834/when-respecting-autonomy-is-harmful-a-clinically-useful-approach-to-the-nocebo-effect
#1
John T Fortunato, Jason Adam Wasserman, Daniel Londyn Menkes
Nocebo effects occur when an adverse effect on the patient arises from the patient's own negative expectations. In accordance with informed consent, providers often disclose information that results in unintended adverse outcomes for the patient. While this may adhere to the principle of autonomy, it violates the doctrine of "primum non nocere," given that side-effect disclosure may cause those side effects. In this article we build off previous work, particularly by Wells and Kaptchuk ( 2012 ) and by Cohen ( 2013 ), to suggest ethical guidelines that permit nondisclosure in the case when a nocebo effect is likely to occur on of the basis of nonmaleficence...
June 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/28459152/risks-of-stimulant-use-for-attention-deficit-hyperactivity-disorder-on-the-developing-brain-primum-non-nocere
#2
H Patrick Stern, Jonathan Lipman, Susan L Andersen, John B Bossaer, Jim Thigpen
No abstract text is available yet for this article.
April 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28294519/the-management-of-the-cardiac-patient-in-labour-primum-non-nocere
#3
Rohan D'Souza, Mathew Sermer, Candice Silversides
Cauldwell et al. discuss three aspects in the management of labour in pregnant women with cardiac disease, for which evidence is limited and most recommendations based on clinical experience. A few points require consideration as expert opinions differ. This article is protected by copyright. All rights reserved.
March 10, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28279268/should-we-screen-for-pulmonary-embolism-in-severe-copd-exacerbations-not-just%C3%A2-yet-primum-non-nocere
#4
EDITORIAL
Seung Won Ra, Don D Sin
No abstract text is available yet for this article.
March 2017: Chest
https://www.readbyqxmd.com/read/28275957/erratum-to-auxiliendo-primum-non-nocere-a-preliminary-view-of-the-devote-trial-comparing-cardiovascular-safety-of-insulin-degludec-versus-insulin-glargine-in-type-2-diabetes
#5
Sanjay Kalra
No abstract text is available yet for this article.
April 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28229272/prophylactic-implantable-cardioverter-defibrillator-in-heart-failure-the-growing-evidence-for-all-or-primum-non-nocere-for-some
#6
REVIEW
Khang-Li Looi, Nigel Lever, Anthony Tang, Sharad Agarwal
Heart failure (HF) is a common health problem and has reached epidemic in many western countries. Despite the current era of HF treatment, the risk of sudden cardiac death (SCD) in HF remains significant. Implantable cardioverter defibrillator (ICD) support has been shown to reduce the risk of SCD in patients with HF and impaired left ventricular function. Prophylactic ICD implantation in HF patients seems a logical step to reduce mortality through a reduction in SCD. However, ICD implantation is an invasive procedure, and both short- and long-term complications can occur...
February 23, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28197833/auxiliendo-primum-non-nocere-a-preliminary-view-of-the-devote-trial-comparing-cardiovascular-safety-of-insulin-degludec-versus-insulin-glargine-in-type-2-diabetes
#7
Sanjay Kalra
A demonstration of cardiovascular safety is mandatory for all newly developed glucose-lowering agents, including insulin analogues. The vascular benefit of insulin is evident from the Diabetes Control and Complication Trial (DCCT) and United Kingdom Prospective Diabetes Study (UKPDS), and the cardiovascular safety of insulin glargine has been demonstrated in individuals with newly diagnosed diabetes or prediabetes in the ORIGIN trial (Outcome Reduction with an Initial Glargine Intervention). The top-line results of DEVOTE (Trial Comparing Cardiovascular Safety of Insulin Degludec vs...
April 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28194188/primum-non-nocere-first-do-no-harm-and-then-feed-peanut
#8
Kyla Jade Hildebrand, Elissa Michele Abrams, Timothy K Vander Leek, Julia Elizabeth Mainwaring Upton, Douglas P Mack, Linda Kirste, Christine McCusker, Sandeep Kapur
The Addendum Guidelines for the Prevention of Peanut Allergy in the United States-Report of the NIAID-Sponsored Expert Panel were developed to build on previous food allergy guidelines after several key studies demonstrated the benefit of early introduction of allergenic foods. These landmark studies including the Learning Early about Peanut (LEAP), LEAP-On and Enquiring about Tolerance trials created a paradigm shift in food allergy prevention. The "take home" messages of this guideline include that peanut should be introduced early in the first year of life, and for the majority of infants, peanut can be introduced at home...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28188998/midwives-experiences-of-working-in-an-obstetric-high-dependency-unit-a-qualitative-study
#9
Isabelle J Eadie, Nicolette F Sheridan
OBJECTIVES: to understand the challenges experienced by midwives providing obstetric high dependency care and identify the training they perceive is needed for work in an obstetric high dependency unit. DESIGN: sixteen midwives who worked in the obstetric high dependency unit participated in one of three focus groups. Focus groups lasted 60-90minutes and were conducted in the workplace and facilitated by author (IE). Data were digitally recorded, transcribed and analysed manually by author (IE), specifically using a 'codebook' model to generate codes, categories and themes...
January 21, 2017: Midwifery
https://www.readbyqxmd.com/read/28160983/primum-non-nocere-advocating-for-a-better-model-in-global-surgery-and-anesthesia
#10
EDITORIAL
Jamey J Snell, Denise M Chan, Craig D McClain
No abstract text is available yet for this article.
January 2017: Journal of Anesthesia History
https://www.readbyqxmd.com/read/28001142/perspective-medical-futility-a-contemporary-review
#11
Ellen Coonan
As medical technology has advanced, the question of medical futility has become a topic of intense debate both within the medical community and within society as a whole. However, a unanimous definition thereof is yet to be decided-some commentators are sceptical as to whether an agreement will ever be reached-and this continues to lead to difficulties, tension, and even legal action when a treating physician disagrees with a patient and/or a patient's family regarding care and treatment options. Although living in a pluralistic society presents one of the major reasons as to why, despite 30 years of intense discussion, no consensus has been made; the issue of medical futility will always be complex as it is, by nature, multifaceted, and numerous elements-including possible risks, evidence of the probability of benefit, the wishes of the patient (and family), professional standards, and cost-interact...
2016: Journal of Clinical Ethics
https://www.readbyqxmd.com/read/27925790/acids-bases-and-apps-primum-non-nocere
#12
Trevor T Nicholson, Thomas C Corbridge
No abstract text is available yet for this article.
December 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27872935/the-social-transformation-of-singapore-medicine-through-55-years-of-the-smj
#13
Ee Heok Kua, Jade Phek Hui Kua
The Singapore Medical Journal (SMJ) has in the past 55 years reflected the phenomenal socioeconomic progress of Singapore. Publications in the pre-independent years were mainly on diseases like cholera, diphtheria, leprosy, tetanus and worm infestation. In the new millennium, the research papers included molecular genetics, health economics, obesity, Internet medicine, cancer, cosmetic surgery and palliative medicine. The annual SMA Lecture published in the SMJ provides an ethical compass for doctors to remind them of primum non nocere...
November 2016: Singapore Medical Journal
https://www.readbyqxmd.com/read/27856317/drug-delivery-by-erythrocytes-primum-non-nocere
#14
REVIEW
Carlos H Villa, Jerard Seghatchian, Vladimir Muzykantov
Red blood cells (RBCs) are naturally capable of transporting diverse cargoes throughout the circulatory system, both loaded to their surface or within their inner volume. Starting largely from the 1970s, diverse approaches for encapsulation into, and surface coupling onto, RBCs have been investigated as potential drug delivery systems. In the last decade, these efforts have yielded diverse strategies to load drugs and nanocarriers to RBCs, and to optimize their pharmacokinetics, distribution, and effects in the body...
December 2016: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/27833193/sonnet-xxx-love-dignity-and-dying
#15
E Wesley Ely
All of us in medicine who care for patients who are chronically critically ill, dying of incurable illnesses, will be faced with discussions about the value of their lives and about the appropriateness of ongoing supportive care. Such discussions are good and true, and they must always be done within the context of the sanctity of every human life and the promise of God that we are His children, each and every one of us. In this article, I explore the end-of-life path of a patient with amyotrophic lateral sclerosis (ALS) and the courageous faith that she demonstrated in the face of her illness...
May 2016: Linacre Quarterly
https://www.readbyqxmd.com/read/27788788/primum-non-nocere-organ-donation-after-electrocution-and-transplantation-of-electricity-damaged-livers-report-of-2-cases
#16
E Giorgakis, M Tedeschi, E Bonaccorsi-Riani, S E Korshandi, H Vilca-Melendez, N Heaton
Liver transplantation remains the treatment of choice for patients with end-stage liver disease. However, allograft availability continues to be a problem, and extending the criteria for organ acceptance is key. Deceased donors after electrical accidents, as well as electricity-traumatized allografts, are not common but should be considered suitable. This study describes 2 cases of heart-beating organ donors with electrical injury to the liver. In 1 case, the electric shock was the cause of death; in the second case, the injury was caused by defibrillation at organ procurement...
October 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27676636/long-term-bisphosphonates-primum-non-nocere
#17
Susan M Ott
No abstract text is available yet for this article.
September 26, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27614695/primum-non-nocere-critically-assessing-the-morbidity-of-prostate-biopsy
#18
EDITORIAL
Boris Gershman, Stephen A Boorjian
No abstract text is available yet for this article.
March 2017: European Urology
https://www.readbyqxmd.com/read/27582999/primum-non-nocere-a-case-of-a-humeral-fracture-in-a-patient-with-fibrodysplasia-progressiva-ossificans
#19
Alun Yewlett, Jeff Kitson, Andrew Redfern, Chris Smith
Fibrodysplasia progressiva ossificans (FPO) is an extremely rare condition characterized by abnormal heterotopic bone formation. The condition is eponymously known as 'stoneman' disease because patients can become effectively entombed within abnormal heterotopic bone. We present the first known case of a diaphyseal humeral fracture managed conservatively in an adult patient with this condition. This patient already had a pre-existing bony bar from a fusion mass involving the thoracic spine, scapula and ribs to her proximal humerus splinting the arm in a position of adduction with the palm of her hand facing towards her groin...
January 2016: Shoulder & Elbow
https://www.readbyqxmd.com/read/27560843/intermittent-androgen-deprivation-primum-non-nocere-first-do-no-harm
#20
Maha Hussain, Mario Eisenberger
No abstract text is available yet for this article.
December 1, 2016: JAMA Oncology
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