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intra abdominal hypertension in children

Mohsen Mazidi, Peyman Rezaie, Andre Pascal Kengne, Maria G Stathopoulou, Mohsen Azimi-Nezhad, Sophie Siest
Metabolic syndrome (MetS) is currently diagnosed by the co-presence of at least three of the five following abnormalities: abdominal obesity, dysglycaemia, elevated serum triglycerides, low high-density cholesterol (HDL) and finally elevated blood pressure. Metabolic syndrome increases the risk of developing cardiovascular disease and diabetes. This review is on the associations between MetS and vascular endothelial growth factor (VEGF). VEGF induces migration and proliferation of endothelial cells (ECs), increases vascular permeability and has a role in tumor growth, adipose tissue expansion, age-related macular degeneration and diabetic retinopathy...
December 9, 2016: Diabetes & Metabolic Syndrome
Arin L Madenci, Alyssa Stetson, Christopher B Weldon, Leslie E Lehmann
Hepatic VOD (veno-occlusive disease) is a serious complication of HSCT (hematopoietic stem cell transplantation) and has historically been associated with high mortality. This obstruction to hepatic flow often results in fluid collections in the peritoneal and pleural cavities. Catheter placement to drain ascites or pleural fluid may reduce intra-abdominal hypertension and/or improve respiratory parameters. The safety of these interventions among critically ill, immunocompromised children is unknown. Among 32 HSCT recipients (2000-2012) with severe VOD, we assessed the primary outcome of procedural complication from peritoneal drain placement...
August 2016: Pediatric Transplantation
Andrew W Kirkpatrick, Derek J Roberts, Roman Jaeschke, Jan J De Waele, Bart L De Keulenaer, Juan Duchesne, Martin Bjorck, Ari Leppäniemi, Janeth C Ejike, Michael Sugrue, Michael L Cheatham, Rao Ivatury, Chad G Ball, Annika Reintam Blaser, Adrian Regli, Zsolt Balogh, Scott D'Amours, Inneke De Laet, Manu L N G Malbrain
The Abdominal Compartment Society ( previously created highly cited Consensus Definitions/Management Guidelines related to intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). Implicit in this previous work, was a commitment to regularly reassess and update in relation to evolving research. Two years preceding the Fifth World Congress on Abdominal Compartment Syndrome, an International Guidelines committee began preparation. An oversight/steering committee formulated key clinical questions regarding IAH/ /ACS based on polling of the Executive to redundancy, structured according to the Patient, Intervention, Comparator, and Outcome (PICO) format...
2015: Anaesthesiology Intensive Therapy
Jan J De Waele, Janeth C Ejike, Ari Leppäniemi, Bart L De Keulenaer, Inneke De Laet, Andrew W Kirkpatrick, Derek J Roberts, Edward Kimball, Rao Ivatury, Manu L N G Malbrain
Intra-abdominal hypertension (IAH) is an important contributor to early organ dysfunction among patients with trauma and sepsis. However, the impact of increased intra-abdominal pressure (IAP) among pediatric, pregnant, non-septic medical patients, and those with severe acute pancreatitis (SAP), obesity, and burns has been studied less extensively. The aim of this review is to outline the pathophysiologic implications and treatment options for IAH and abdominal compartment syndrome (ACS) for the above patient populations...
2015: Anaesthesiology Intensive Therapy
Farah Chedly Thabet, Iheb Mohamed Bougmiza, May Said Chehab, Hind Ali Bafaqih, Sulaiman Abdulkareem AlMohaimeed, Manu L N G Malbrain
PURPOSE: To assess the incidence, risk factors, and outcomes of intra-abdominal hypertension (IAH) in a pediatric intensive care unit (PICU). METHODS: Prospective cohort study from January 2011 to January 2013. All children consecutively admitted to the PICU, staying more than 24 hours and requiring bladder catheterization, were included in the study. On admission, demographic data and risk factors for IAH were studied. The intra-abdominal pressure was measured every 6 hours through a bladder catheter until discharge, death, or removal of the catheter...
July 2016: Journal of Intensive Care Medicine
Yu-Jian Liang, Hui-min Huang, Hong-ling Yang, Ling-ling Xu, Li-dan Zhang, Su-ping Li, Wen Tang
BACKGROUND: Children with massive ascites can develop abdominal compartment syndrome (ACS), which has been identified as an independent risk factor for mortality. OBJECTIVES: The objective of this study was to assess the effectiveness of volume-controlled percutaneous catheter drainage (PCD) for treating children with massive ascites and ACS. METHODS: A retrospective descriptive study was conducted; Comprising 12patients with ACS with massive ascites treated with volume-controlled PCD in a pediatric intensive care unitof a university hospital in southern China from April 2011 to June 2013...
2015: Italian Journal of Pediatrics
Nune Matinyan, Alexander Saltanov, Leonid Martynov, Anatolij Kazantsev
Wilms tumour (WT) (or nephroblastoma) is one of the most common malignant kidney tumors in children. On subsequent stages clinically it is often characterized by abdominal hypertension syndrome, which, in turn, leads to development of respiratory insufficiency. Other symptoms comprise renal deficiency, hypertension, and abnormalities of hemostasis and hemogram. Treatment includes rounds of preoperative chemotherapy and subsequent surgery. We report a case of perioperative management for nephrectomy in 20-month-old patient with a giant unilateral WT...
2015: Case Reports in Anesthesiology
Jyoti Singhal, Preeti Shanbag
INTRODUCTION: It is being increasingly recognized that intra-abdominal hypertension is an important cause of organ dysfunction. This pilot study was done to determine the feasibility of measuring intra-abdominal pressures (IAP) in critically-ill children using simple inexpensive equipment available in the PICU. MATERIALS AND METHODS: This was a prospective study done in the paediatric intensive care unit (PICU) of a tertiary care general hospital. Thirty-two consecutive patients admitted to the PICU, staying for more than 24 h and requiring a urinary catheter were studied...
December 2014: Journal of Clinical and Diagnostic Research: JCDR
Tarja Kunnas, Seppo T Nikkari
BACKGROUND: A human syndecan-4 genetic variant (rs1981429) has previously been associated with lean tissue mass and intra-abdominal fat, and SNP rs4599 with resting energy expenditure in healthy early pubertal children. These variations could thus cause overweight and hypothetically lead to hypertension. Their association with body mass index and blood pressure was therefore studied in a Finnish cohort of adults. METHODS: The data was collected from the Tampere adult population cardiovascular risk study (TAMRISK)...
2014: BMC Research Notes
E Marty Knott, Jason D Fraser, Hanna Alemayahu, William B Drake, Shawn D St Peter, Kathy M Perryman, David Juang
INTRODUCTION: Patients with single ventricle physiology (SVP)--specifically, hypoplastic left heart syndrome (HLHS)--frequently need long-term enteral access; however, they are at an extremely high operative risk. Nothing has been published on the physiologic impact on single ventricle function during laparoscopy in this patient population. Therefore, we performed intraoperative transesophageal echocardiography (TEE) to study the physiologic effects of laparoscopic surgery in these patients...
October 2014: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
YuJian Liang, LingLing Xu, Wen Tang
No abstract text is available yet for this article.
July 2014: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Cyriac Abby Philips, Lovkesh Anand, K N Chandan Kumar, Vivek Kasana, Ankur Arora
We present a rare case of spontaneous trans-splenic shunt and intra-splenic collaterals in a patient with liver cirrhosis and portal hypertension. The shunt and presence of cirrhosis and portal hypertension was incidentally detected by abdominal computed tomographic imaging during evaluation for abdominal pain. There has been a single report on the presence of trans-splenic shunt in two children with extra-hepatic portal venous obstruction but no cases that report intra-splenic collaterals: to the best of our knowledge, this is the first reported case of spontaneous trans-splenic shunt in the presence of intra-splenic collaterals and incidental multiple splenic artery aneurysms that developed in an adult with compensated cirrhosis and portal hypertension...
May 2015: Gastroenterology Report
J J De Waele, I De Laet, M L N G Malbrain
INTRODUCTION: Intraabdominal hypertension (IAH) is increasingly appreciated by intensivists as an important cause of organ dysfunction, even at pressure levels which were previously thought to be harmless. Therefore, the goal of this review is to describe the different methods commonly used in clinical practice for intraabdominal pressure (IAP) measurement, the advised methodology for each measurement method, and finally to give a rational approach for IAP monitoring in daily clinical practice...
2007: Acta Clinica Belgica
W Sandmann, P Dueppers, S Pourhassan, A Voiculescu, D Klee, K M Balzer
OBJECTIVES: This retrospective study presents the early and late results of pediatric patients who underwent reconstructive surgery for renovascular hypertension (RVH) between 1979 and 2009. METHODS: From 1979 to 2009 44 patients (male 22; mean age 13±5.2 years, range 1-19 years; early childhood 7 [1-6 years], middle childhood 5 [7-10 years]; adolescents 32 [11-19 years]) with renovascular hypertension underwent surgery for abdominal aortic stenoses (n=6), renal artery stenosis (RAS) (n=25) or for combined lesions (n=13)...
May 2014: European Journal of Vascular and Endovascular Surgery
Dustin Jacobson, Jonathan Gilleland, Brian Cameron, Ehud Rosenbloom
BACKGROUND: Perinephric abscesses in children are rare. Infection can come from various areas, and clinical signs overlap with more common etiologies, such as pyelonephritis. Imaging modalities and laboratory investigations help lead to a definitive diagnosis. CASE-DIAGNOSIS/TREATMENT: We present a case of a 5-month-old infant presenting with a febrile illness and eventual diagnosis of a perinephric abscess causing abdominal compartment syndrome. The infant had no known risk factors, i...
May 2014: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
Emre Divarcı, Orkan Ergün, Bülent Karapınar, Mehmet Yalaz, Ahmet Celik
BACKGROUND: Increased intra-abdominal pressure (IAP) can result in multiorgan failure. Trauma, mechanical bowel obstruction (MBO), abdominal wall defects (AWD) and fluid resuscitation in septic shock are conditions associated with a high risk of increased IAP in children. It may be possible to treat these conditions more effectively using intravesical pressure measurement. METHODS: This prospective study was performed between December 2009 and October 2010. Intravesical pressure (IVP) measurement was used to determine IAP...
November 2013: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
Hashim A Periyalil, Peter G Gibson, Lisa G Wood
Obesity is now recognised as a worldwide epidemic. The recent International Association for the Study of Obesity/International Obesity Taskforce (IASO/IOTF) analysis estimates that approximately 1.0 billion adults are currently overweight and a further 475 million are obese. Obesity has huge psychosocial impact with obese children and adolescents facing discrimination and stigmatization in many areas of their lives leading to body dissatisfaction, low self-esteem and depression. Indeed, obesity is recognised as an important risk factor for the development of several chronic diseases such as hypertension, cancer, asthma and metabolic syndrome...
September 2013: Nutrients
Michael D Rollins, Jorge Deamorim-Filho, Eric R Scaife, Anna Hubbard, Douglas C Barnhart
PURPOSE: Abdominal compartment syndrome (ACS) may complicate ECMO due to significant fluid shifts resulting in tense ascites and interstitial edema. This compromises venous cannula flow leading to inadequate patient support. It is debatable whether decompressive laparotomy should be performed in these patients due to the risk of bleeding and poor prognosis. We sought to evaluate the effect of decompressive laparotomy on ECMO support and patient survival. METHODS: We reviewed our tertiary care children's hospital ECMO registry (2000-2011) identifying those who underwent decompressive laparotomy...
July 2013: Journal of Pediatric Surgery
Du-Fei Zhang, Xiao-Wei Feng, Tao Lin, Kai-Fang Wu
OBJECTIVE: To study risk factors for the occurrence of intra-abdominal hypertension (IAH) in children with sepsis. METHODS: A nest case-control study was employed. According to intra-abdominal pressures (IAP) measured by cystometry, 119 children with sepsis were classified into normal IAP (control, n = 80) and IAH groups (n = 39). Risk factors for the occurrence of IAH were investigated by monovariable and multivariable logistic regression analysis. RESULTS: Monovariable analysis showed that there were significant differences in pediatric critical illness score (PCIS), procalcitonin (PCT) level, PaCO(2), blood lactate level, rates of intestinal or intra-abdominal infection, ascites, gastrointestinal dysfunction, mechanical ventilation, shock and multiple organ dysfunction syndrome (MODS) between the IAH and control groups (P < 0...
July 2013: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Enric Reverter, Annabel Blasi, Juan G Abraldes, Graciela Martínez-Palli, Susana Seijo, Fanny Turon, Annalisa Berzigotti, Jaume Balust, Jaume Bosch, Juan C García-Pagán
BACKGROUND & AIMS: Measurement of the hepatic venous pressure gradient (HVPG) offers valuable prognostic information in patients with cirrhosis. In specific circumstances, (children, agitated patients, TIPS placement) deep sedation is required. This study aims to assess the impact of deep sedation on the accuracy of hepatic/portal pressure measurements. METHODS: Forty-four patients were included. Measurements of baseline HVPG (n = 30), HVPG response to i.v. propranolol (n = 11), portal pressure gradient (PPG) after TIPS (n = 27) and of cardio-pulmonary pressures (n = 25) were obtained in awake conditions and under deep sedation with propofol and remifentanil...
January 2014: Liver International: Official Journal of the International Association for the Study of the Liver
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