Read by QxMD icon Read

Spine surgery neoplasm second

Satoshi Kato, Alessandro Gasbarrini, Riccardo Ghermandi, Marco Gambarotti, Stefano Bandiera
PURPOSE: Chordoma is a rare, locally aggressive neoplasm of the bone that arises from embryonic notochordal remnants. In less than 5 % of cases, chordomas contain a highly malignant sarcomatous component. Because of the rarity of such tumors, little is known about their clinical features and optimal treatment options. Herein, we report two chordoma cases with malignant sarcomatoid areas, consistent with high-grade osteosarcoma in the primary spine lesions, and discuss the presentation and characteristics of this disease...
May 2016: European Spine Journal
N A Konovalov, I N Shevelev, A G Nazarenko, D S Asiutin, V A Korolishin, S Iu Timonin, B A Zakirov, R A Onoprienko
AIM: To conduct a comparative analysis of outcomes in patients with extramedullary tumors operated on using a minimally invasive approach and traditional laminectomy. MATERIAL AND METHODS: The study included 40 patients (13 males and 27 females) who underwent surgical treatment at the Department of Spinal Neurosurgery of the Burdenko Neurosurgical Institute. The mean age of patients was 47 years (range: 41-60 years). Tumors were located in the cervical, thoracic and lumbar spine...
2014: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
M Quiriny, M Moreau, J Alexiou, G Andry
The aim of this study is to compare our surgical results of parathyroidectomies in primary hyperparathyroidism with literature results. From 1985 until 2009, 167 patients were operated for primary hyperparathyroidism by bilateral central neck exploration. The sex ratio (women/men) is 4/1 and the middle age is 57 years old. We record clinical information, laboratory and radiological results of the preoperative period. We count 158 adenomas, 5 parathyroid hyperplasias, two carcinomas and two parathyroid glands reported as normal...
March 2014: Acta Chirurgica Belgica
Ali K Ozturk, Ziya L Gokaslan, Jean-Paul Wolinsky
Primary sarcomas of the spine are rare diseases and include osteosarcoma, chondrosarcoma, chordoma, and Ewing's sarcoma. Surgery for these lesions remains an important part of their treatment. Strong evidence exists for the en bloc resection of chondrosarcoma and chordoma since these lesions respond poorly to both chemotherapy and radiation. Weaker but important evidence suggests that osteosarcoma and Ewing's sarcoma may also benefit from wide excisions, but after the application of neoadjuvant therapy, which may significantly aid the surgical process as well as independently prolong the survival...
September 2014: Current Treatment Options in Oncology
Patricia L Robertson, Regina Jakacki, Juliette Hukin, Joao Siffert, Jeffrey C Allen
In order to improve outcomes for CNS mixed malignant germ cell tumors (MMGCT) we sought to increase complete responses (CR) to initial therapy, through intensifying neoadjuvant chemotherapy (CHT1) with added ifosfamide, encouraging second-look surgery, and administering dose-intensive, stem cell-supported chemotherapy (CHT2) to patients with residual tumor, all prior to radiation therapy (RT). Diagnosis was confirmed by biopsy or elevated germ cell tumor markers. After tumor staging was completed, patients received four cycles of chemotherapy (cisplatin, etoposide and ifosfamide, "CHT1")...
May 2014: Journal of Neuro-oncology
Xiao Li, Wei Guo, Rong-li Yang, Yi Yang
OBJECTIVE: To explore the clinical profiles, imaging features and prognosis of patient with multicentric giant cell tumor of bone (MGCT). METHODS: Nine MGCT patients treated at our hospital between 1997 and 2010 were retrospectively examined. They had two or more separate lesions of giant cell tumor. There were 5 males and 4 females with an average age of 23 (14-37) years. Three patients (33%) were under 20 years old. There were 29 tumors in the series with an average of 3...
December 3, 2013: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Francisco Verdú-López, Rudolf Beisse
INTRODUCTION: Thoracoscopic surgery or video-assisted thoracic surgery (VATS) of the thoracic and lumbar spine has evolved greatly since it appeared less than 20 years ago. It is currently used in a large number of processes and injuries. The aim of this article, in its two parts, is to review the current status of VATS of the thoracic and lumbar spine in its entire spectrum. DEVELOPMENT: After reviewing the current literature, we developed each of the large groups of indications where VATS takes place, one by one...
March 2014: Neurocirugía
Satoshi Kato, Hideki Murakami, Akihiko Takeuchi, Satoru Demura, Katsuhito Yoshioka, Norio Kawahara, Katsuro Tomita, Hiroyuki Tsuchiya
This article describes a patient with multiple metastases from renal cell carcinoma who survived and maintained an ambulatory status for 15 years with no recurrence in the spine after en bloc resection of solitary spinal metastasis. Skeletal metastasis from renal cell carcinoma is common, second only to lung metastasis. Surgery plays an important role in the treatment of the metastasis because of its resistance to chemotherapy and radiotherapy. A 60-year-old man had T1N2M1 renal cell carcinoma in the right kidney and synchronous bone metastases at T12 vertebral body and the right humerus...
November 2013: Orthopedics
Ahmet Levent Aydin, Mehdi Sasani, Tunc Oktenoglu, Ihsan Solaroglu, Ali Fahir Ozer
AIM: Chordoma is a rare, slow-growing primary malignant tumor of the axial skeleton, arising from the embryonic cells of primitive notochord. Chordomas may arise at different sites of the vertebral column simultaneously or more probably they may metastasise along the neural axis insidiously. Recurrence despite radical surgery and following adjuvant therapy is possible. MATERIAL AND METHODS: A 46-year-old female patient presented weakness and numbness of the lower extremities...
2013: Turkish Neurosurgery
P Sutcliffe, M Connock, D Shyangdan, R Court, N-B Kandala, A Clarke
BACKGROUND: Spinal metastases can lead to significant morbidity and reduction in quality of life due to spinal cord compression (SCC). Between 5% and 20% of patients with spinal metastases develop metastatic spinal cord compression during the course of their disease. An early study estimated average survival for patients with SCC to be between 3 and 7 months, with a 36% probability of survival to 12 months. An understanding of the natural history and early diagnosis of spinal metastases and prediction of collapse of the metastatic vertebrae are important...
September 2013: Health Technology Assessment: HTA
Christian Blume, Marec von Lehe, Frank van Landeghem, Susanne Greschus, Jan Boström
BACKGROUND: Extraneural and extracranial metastases of glioblastoma (GB) are very rarely reported in the literature. They occur in only 0.2% of all GB patients. CASE PRESENTATION: We present a 40 year old caucasian male with secondary GB and first diagnosis of an astrocytoma world health organisation (WHO) grade II through stereotactic biopsy in 2006. He presented a new hemiparesis and a progress of the known mass lesion in 2008. Subtotal tumor resection was performed and the histological examination verified a GB...
2013: BMC Research Notes
Stavros I Stavridis, Andreas Pingel, Klaus John Schnake, Frank Kandziora
INTRODUCTION: Osteoblastoma is a rare, benign bone tumor that accounts for approximately 1% of all primary bone tumors and 5% of spinal tumors, mostly arising within the posterior elements of the spine within the second and third decades of life. Nonspecific initial symptoms mainly neck or back pain and stiffness of the spine remain often undiagnosed and the destructive nature of the expanding tumor can cause even neurological deficits. CT and MRI scans constitute the basic imaging modalities employed in diagnosis and preoperative planning with the former delineating the location and osseous involvement of the mass and the latter providing appreciation of the effect on soft tissues and neural elements...
November 2013: European Spine Journal
Hee-Sang Kim, Jong Eon Lee, Sang Soo Jung, Jinmann Chon, Dong Hwan Yoon, Yong-Koo Park, Eun Hye Cho
Giant cell tumor (GCT) is a relatively rare neoplasm. In GCT, the bone affection of the axial skeleton is extremely rare. Most GCT arises in the meta-epiphyseal ends of the long bones. Its peak incidence is between 30 to 40 years of age. GCT is usually classified as benign, but shows locally aggressive behavior and may occasionally undergo a malignant transformation. The patients with GCT in the spine often complain of the lower back pains, as the tumors primarily involve the sacrum. We report a case of an adolescent female complaining of the upper back pain with a sudden weakness of the lower extremities, later diagnosed with the GCT of the T2 vertebra...
April 2013: Annals of Rehabilitation Medicine
V Agarwal, G Sreedher, K R Weiss, M A Hughes
Painful vertebral body hemangiomas have been successfully treated with vertebroplasty and kyphoplasty. Sacral hemangiomas are uncommon and as such painful sacral hemangiomas are rare entities. We report what we believe is only the second successful treatment of a painful sacral hemangioma with CT-guided sacroplasty. A 56-year-old woman with a history of right-sided total hip arthroplasty and lipoma excision presented to her orthopedic surgeon with persistent right-sided low back pain which radiated into her buttock and right groin and hindered her ability to walk and perform her activities of daily living...
June 2013: Interventional Neuroradiology
Michal Tomek, Ilaria Bravi, Nigel Mendoza, Ali Alsafi, Amrish Mehta, Luca Molinaro, Poonam Singh, Bishan Radotra, Angelo P Dei Tos, Federico Roncaroli
We report a 66-year-old man with a spinal, extradural solitary fibrous tumor showing unique retiform and papillary architecture. The patient presented in May 2008 with worsening right-sided lower back pain and urinary frequency. Magnetic resonance imaging of the spine documented a heterogeneously enhancing dumbbell-shaped extradural lesion causing cord compression at T11/12 level. The tumor extended to the paravertebral soft tissue and invaded the right adjacent vertebral pedicles and laminae. An angiogram showed prominent vascular supply mainly from the right T11 radicular artery...
June 2013: Annals of Diagnostic Pathology
Qing Zhu, Ming Qian, Jianru Xiao, Zhipeng Wu, Yu Wang, Jishen Zhang
OBJECT: Calcified meningiomas are an uncommon type of meningioma. This study details the clinical features, treatment, and follow-up of 11 calcified meningiomas treated from 2002 to 2009, for the purpose of providing general information, describing the skill required for the surgery, and detailing the imaging study of these tumors. METHODS: Between 2002 and 2009, 11 patients underwent surgery for the treatment of calcified meningiomas. All were treated by the same group of doctors at the same institution, including surgery and rehabilitation after surgery...
May 2013: Journal of Neurosurgery. Spine
Wei Wu, Feng Li, Zhong Fang, Wei Xiong, Han-feng Guan, Jun Xiao, Feng-jin Guo, An-min Chen
As a result of the complex anatomy in upper cervical spine, the operative treatment of axis neoplasms is always complicated. Although the procedure for the second cervical vertebra (C2) surgery had been described previously in diverse approaches and reconstruction forms, each has its own limitations and restrictions that usually result in less satisfactory conclusions. The purpose of this study was to evaluate the operation efficacy for axis tumors by using a combined anterior (retropharyngeal) cervical and posterior approach in achieving total resection of C2 and circumferential reconstruction...
February 2013: Journal of Huazhong University of Science and Technology. Medical Sciences
M Popescu, Viola Popov, G Popescu, Camelia Dobrea, Aurelia Sandu, V T Grigorean, V Strâmbu
UNLABELLED: Primary spinal involvement in hematological diseases is rare. PURPOSE: The purpose of this article is studying diagnostic and treatment strategies in patients with spinal cord primary hematologic tumors causing spinal cord compression syndrome. PATIENTS AND METHODS: We report two cases with spinal cord primary hematologic tumors causing spinal cord compression syndrome. One patient had a diffuse large B-cell non-Hodgkin's lymphoma located in the thoracic spine and the second patient had a plasmocytic plasmacytoma located in the thoraco-lumbar spine...
2012: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
Hui-ren Wang, Sheng-sheng Cao, Yun-qi Jiang, Jun-ning Li, Xi-lei Li, Yun-gen Fu, Ming-dong Zhao, Jian Dong
OBJECTIVE: To study the therapeutic efficacy of the "sandwich" method (medical glue + gelatin sponge + medical glue) of spinal dural repair for preventing cerebrospinal fluid (CSF) leaks during treatment of subdural tumors. METHODS: Fifty-four patients with spinal subdural tumors treated between April 2007 and June 2011 were retrospectively investigated. The patients were divided into two groups: a conventional group (group A) and a "sandwich" group (group B)...
November 2012: Orthopaedic Surgery
Toru Sasamori, Kazutoshi Hida, Shunsuke Yano, Takeshi Aoyama, Takeshi Asano, Kanako Kubota, Manabu Ito, Kuniyoshi Abumi, Yoshinobu Iwasaki, Hisatoshi Saito, Kiyohiro Houkin
A 25-year-old man presented with malignant transformation to malignant peripheral nerve sheath tumor (MPNST) in the cervical spine associated with neurofibromatosis type 1. He presented with a 3-week history of rapidly increasing weakness and numbness in all four extremities. Magnetic resonance (MR) imaging of the cervical spine demonstrated a dumbbell-shaped tumor, which compressed the spinal cord at the C2-3 level. The tumor was excised, mainly within the spinal canal to decompress the spinal cord. The histological diagnosis was benign neurofibroma...
2012: Neurologia Medico-chirurgica
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"