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https://www.readbyqxmd.com/read/29140905/gender-confirmation-surgery-using-the-pedicle-transverse-colon-flap-for-vaginal-reconstruction-a-clinical-outcome-and-sexual-function-evaluation-study
#1
Oscar J Manrique, M Diya Sabbagh, Pedro Ciudad, Jorys Martinez-Jorge, Kidakorn Kiranantawat, Ngamcherd Sitpahul, Todd B Nippoldt, Ali Charafeddine, Hung-Chi Chen
INTRODUCTION: Vaginal reconstruction and vaginoplasty are indicated in vaginal agenesis, following pelvic tumor resection, trauma and for gender confirmation surgery. Different surgical options have been described when using these techniques. Herein, we present the clinical outcomes and sexual function evaluation using the pedicle transverse colon flap (TCF) for gender confirmation surgery in transgender women. METHODS: This is a retrospective chart review of all transgender women who underwent gender confirmation surgery using the pedicle TCF...
November 11, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29138058/the-diagnostic-value-and-histologic-correlate-of-distinct-patterns-of-shiny-white-streaks-for-the-diagnosis-of-melanoma-a-retrospective-case-control-study
#2
Anna Eliza Verzi, Victor L Quan, Kara Walton, Mary C Martini, Ashfaq A Marghoob, Erin M Garfield, Betty Kong, Maria Cristina Isales, Timothy VandenBoom, Bin Zhang, Dennis West, Pedram Gerami
BACKGROUND: Shiny white streaks (SWS) are best visualized with polarized dermoscopy, and correlate with dermal fibroplasia histopathologically. SWS have been described at higher frequencies in melanomas than benign nevi. OBJECTIVE: We assessed the diagnostic value of different patterns of SWS and their histologic correlate in melanocytic lesions. METHODS: Polarized dermoscopic images of 1507 histopathologically diagnosed melanocytic neoplasms were analyzed for presence and pattern of SWS...
November 11, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29128275/a-longitudinal-study-of-motivations-before-and-psychosexual-outcomes-after-genital-gender-confirming-surgery-in-transmen
#3
Tim C van de Grift, Garry L S Pigot, Siham Boudhan, Lian Elfering, Baudewijntje P C Kreukels, Luk A C L Gijs, Marlon E Buncamper, Müjde Özer, Wouter van der Sluis, Eric J H Meuleman, Mark-Bram Bouman, Margriet G Mullender
BACKGROUND: Genital dissatisfaction is an important reason for transmen to undergo genital gender-confirming surgery (GCS; phalloplasty or metoidioplasty). However, little is known about motives for choosing specific techniques, how transmen benefit postoperatively, and whether psychosexual outcomes improve. AIM: To evaluate motivations for and psychosexual outcomes after GCS. METHODS: A longitudinal study of 21 transmen at least 1 year after GCS was conducted...
November 8, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29122742/myotube-migration-to-cover-and-shape-the-testis-of-drosophila-depends-on-heartless-cadherin-catenin-and-myosin-ii
#4
Silke Rothenbusch-Fender, Katharina Fritzen, Maik C Bischoff, Detlev Buttgereit, Susanne F Oenel, Renate Renkawitz-Pohl
During Drosophila metamorphosis, nascent testis myotubes migrate from the prospective seminal vesicle of the genital disc onto pupal testes and then further to cover the testes with multinucleated smooth-like muscles. Here we show that DWnt2 is likely required for determination of testis-relevant myoblasts on the genital disc. Knock down of FGFR Heartless by RNAi and a dominant-negative version revealed multiple functions of Heartless, namely regulation of the amount of myoblasts on the genital disc, connection of seminal vesicles and testes, and migration of muscles along the testes...
November 9, 2017: Biology Open
https://www.readbyqxmd.com/read/29076692/genital-tuberculosis-mimicking-carcinoma-ovary-can-ultrasound-guided-biopsy-be-a-resolution
#5
Nosheen Akhtar, Zartaj Hayat, Fatima Nazim
Genital tuberculosis mimicking carcinoma ovary is a well-known dilemma as there is no definitive serological or imaging modality for diagnosing abdominopelvic tuberculosis. A 20-years-old unmarried girl presented with complex adnexal mass, mild ascites and CA 125 >1000. Her staging laparotomy and frozen section was planned. Laparotomy revealed miliary tuberculosis and frozen section confirmed the diagnosis of tuberculosis. Patient was started with anti-tuberculosis treatment and follow up showed resolution of cysts...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29069622/intramuscular-delivery-of-replication-defective-herpes-simplex-virus-gives-antigen-expression-in-muscle-syncytia-and-improved-protection-against-pathogenic-hsv-2-strains
#6
Fernando Diaz, Sean Gregory, Hiroshi Nakashima, Mariano S Viapiano, David M Knipe
Herpes simplex virus 2 (HSV-2) is the leading cause of genital herpes and increases the risk of HIV infection, but there is no effective vaccine. A replication-defective HSV-2 mutant virus, dl5-29, is effective in animal models and has been in a phase I trial. Previous studies have shown that dl5-29 gives higher antibody responses and better protection when inoculated intramuscularly (IM) as compared with subcutaneously (SC). However, the basis for this effect has not been defined. We confirmed that IM inoculation of dl5-29 is more immunogenic and provides better protection than SC inoculation...
October 22, 2017: Virology
https://www.readbyqxmd.com/read/29057436/non-invasive-therapeutic-use-of-high-intensity-focused-ultrasound-hifu-with-3-tesla-magnetic-resonance-imaging-in-women-with-symptomatic-uterine-fibroids
#7
Tomasz Łoziński, Justyna Filipowska, Grzegorz Gurynowicz, Iwona Gabriel, Artur Czekierdowski
Benign uterine fibroids are common female genital tract tumors and if symptomatic often require extensive surgery. When tumors are multiple and large or unusually located, the operative treatment may lead to significant morbidity and compromise quality of life. Recovery period after surgical treatment may be complicated by patient's medical condition and wound healing problems. Currently used other non-surgical treatment modalities usually provide only a temporal symptoms relief and may not be efficient in all affected women...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/29055822/anabolic-steroid-use-among-gay-and-bisexual-men-living-in-australia-and-new-zealand-associations-with-demographics-body-dissatisfaction-eating-disorder-psychopathology-and-quality-of-life
#8
Scott Griffiths, Stuart B Murray, Matthew Dunn, Aaron J Blashill
BACKGROUND AND AIMS: Gay and bisexual men may be at heightened risk for using anabolic androgenic steroids (AAS). Few studies, however, have examined AAS use among gay and bisexual men living in countries outside the United States. In addition, few studies have explored the potential associations of AAS use with body image concerns beyond muscularity, including height and genitals, or with eating disorder symptoms and quality of life. Thus, we examined the associations of AAS use, and of thoughts about using AAS, with body image, eating disorder symptoms, and quality of life among gay and bisexual men living in Australia and New Zealand...
October 18, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29055448/a-case-of-mog-antibody-positive-bilateral-optic-neuritis-and-meningoganglionitis-following-a-genital-herpes-simplex-virus-infection
#9
Masataka Nakamura, Yuko Iwasaki, Toshiyuki Takahashi, Kimihiko Kaneko, Ichiro Nakashima, Takenobu Kunieda, Satoshi Kaneko, Hirofumi Kusaka
BACKGROUND: Myelin oligodendrocyte glycoprotein (MOG) antibody-positive optic neuritis (ON) and myelitis are recognized as important differential diagnosis of aquaporin-4 (AQP4) antibody-positive neuromyelitis optica (NMO)/NMO spectrum disorder (NMOSD). Similar to NMO/NMOSD associated with AQP4 antibodies, preceding infections have been reported in patients with MOG antibody-positive ON. This is the first report of bilateral ON following a herpes simplex virus (HSV) infection associated with a positive MOG antibody...
October 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29055285/delayed-spontaneous-resorption-of-lumbar-intervertebral-disc-herniation-a-case-report
#10
You Jin Jung, Joon-Shik Shin, Jinho Lee, Yoon Jae Lee, Me-Riong Kim, In-Hyuk Ha
Background • Large intervertebral disc herniation is often managed with surgery, but it is not uncommon for spontaneous resorption of herniated disc material to occur. Although the majority of spontaneous disc resorption occurs in the acute phase, an unusual case of delayed intervertebral disc regression at 18 mo postonset is presented. Case Presentation • A 32-y-old female patient presented with acute low-back pain and pain in both legs a Korean medicine hospital specializing in spinal disorders. Massive intervertebral disc herniation was found on lumbar magnetic resonance imaging (MRI), and inguinal and genital pain and numbness was suggestive of risk of cauda equina syndrome...
October 21, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29054075/evaluation-of-immunological-markers-of-ovine-vaginal-irritation-implications-for-preclinical-assessment-of-non-vaccine-hiv-preventive-agents
#11
Gregg N Milligan, Gracie Vargas, Kathleen L Vincent, Yong Zhu, Nigel Bourne, Massoud Motamedi
The presence of genital inflammatory responses and a compromised vaginal epithelial barrier have been linked to an increased risk of HIV acquisition. It is important to assure that application of candidate microbicides designed to limit HIV transmission will not cause these adverse events. We previously developed high resolution in vivo imaging methodologies in sheep to assess epithelial integrity following vaginal application of a model microbicide, however characterization of genital inflammation in sheep has not been previously possible...
October 13, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29026416/right-ventricular-thrombosis-as-a-manifestation-of-beh%C3%A3-et-s-syndrome
#12
Payam Ebrahimifar, Javad Shahabi
BACKGROUND: Behçet's disease (BD) is a rare condition with a classic triad of oral and genital ulceration and eye disease. Cardiovascular complication is a rare finding in BD. CASE REPORT: In this report, we present a seventeen years old patient with a history of fever for 20 days, who developed a clot in right ventricle (RV). Cardiac magnetic resonance imaging (MRI) and echocardiography demonstrated a thrombosis in RV and a thoracic multi detector computed tomographic image showed pulmonary thromboembolism (PTE) in patient...
March 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29021078/sexual-dys-functioning-is-related-to-drive-for-thinness-not-drive-for-muscularity
#13
Anandi Alperin, Fiona K Barlow
Background: Negative body image can result in sexual dysfunction for both women and men. Drive for thinness, drive for muscularity and drive for leanness have all been associated with poor body image. However, research to date has not examined which is the strongest predictor of sexual problems in each gender. Methods: The present study used measures of drive for muscularity and drive for thinness simultaneously to predict sexual functioning in both genders. Participants (n=519) completed measures of drive for thinness, drive for muscularity, sexual esteem, sexual assertiveness, discomfort exposing their bodies during sex and genital satisfaction...
October 12, 2017: Sexual Health
https://www.readbyqxmd.com/read/28993226/vulvar-lesions-in-an-8-year-old-girl-cutaneous-manifestations-of-multisystem-langerhans-cell-histiocytosis
#14
Elisa M Jorgensen, Peter P Chen, Sarah Rutter, Julia A Cron
BACKGROUND: Langerhans cell histiocytosis (LCH) is a rare localized or systemic disease characterized by proliferation of myeloid-derived dendritic cells. Vulvar lesions may be the herald symptom of LCH and may mimic other cutaneous lesions. Prognosis varies widely based on the extent and spread of disease. CASE: An 8-year-old girl with a 4-month history of vulvar lesions resistant to topical steroids was referred by her pediatrician. Vulvar biopsy was diagnostic for LCH...
October 6, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28986148/brain-activity-unique-to-orgasm-in-women-an-fmri-analysis
#15
Nan J Wise, Eleni Frangos, Barry R Komisaruk
BACKGROUND: Although the literature on imaging of regional brain activity during sexual arousal in women and men is extensive and largely consistent, that on orgasm is relatively limited and variable, owing in part to the methodologic challenges posed by variability in latency to orgasm in participants and head movement. AIM: To compare brain activity at orgasm (self- and partner-induced) with that at the onset of genital stimulation, immediately before the onset of orgasm, and immediately after the cessation of orgasm and to upgrade the methodology for obtaining and analyzing functional magnetic resonance imaging (fMRI) findings...
November 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28983164/extensively-metastasizing-leiomyosarcoma-a-diagnostic-challenge
#16
Arvind Ahuja, Poojan Agarwal, Rohan Sardana, Suryanarayanan Bhaskar
Uterine leiomyosarcoma (ULMS) is a rare malignancy of the female genital tract and carries an extremely poor 5-year survival rate. It is known to metastasize early and to distant sites owing to a high propensity for hematogeneous spread. Lung, peritoneum, liver, and bone are relatively common sites of metastasis. Patient age, tumor size, FIGO stage, and grade of the tumor are important criteria for predicting metastasis. The incidence of ULMS is increasing, probably due to the use of improved imaging techniques and as a result of cancer patients' prolonged life expectancy...
July 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28974871/imperforate-hymen-varied-presentation-new-associations-and-management
#17
Raghu Sampally Ramareddy, Anjala Kumar, Anand Alladi
AIM: Imperforate hymen is an isolated and sporadic event. The aim of this study was to report varied clinical and management problems of consecutive imperforate hymen in children and to compare the genetic review with literature. MATERIALS AND METHODS: This is a retrospective analysis of eight consecutive imperforate hymen children admitted during 2010-2015. RESULTS: Among eight girls, two were infants and six were in the adolescent group...
October 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28964932/predictors-of-female-genital-organ-involvement-in-radical-cystectomy-for-urothelial-carcinoma-of-the-bladder-a-single-center-retrospective-analysis-of-112-female-patients
#18
Se Young Choi, Sangjun Yoo, Jae Hyeon Han, In Gab Jeong, Bumsik Hong, Jun Hyuk Hong, Hanjong Ahn, Choung-Soo Kim, Dalsan You
OBJECTIVES: To evaluate predictors of organ involvement and oncological outcomes after radical cystectomy with anterior exenteration in female patients. METHODS: Among 1198 patients who underwent radical cystectomy for the bladder tumor between 1990 and 2015, 178 (14.9%) patients were female. They were divided into two groups according to pelvic involvement in pathology. Their medical records and pathology and image findings were reviewed retrospectively. Non-urothelial cell carcinoma and no genital organ pathology were excluded...
November 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28946589/what-is-known-about-sexual-health-after-pediatric-acquired-brain-injury-a-scoping-review
#19
Grahame Simpson, Martine Simons-Coghill, Annerley Bates, Caron Gan
BACKGROUND: Positive sexual development is a core task in the transition from childhood/adolescence to adulthood. Little is known about the extent of research addressing this topic after acquired brain injury (ABI). OBJECTIVE: To identify publications (1980 to 2016) addressing positive sexual health among children/adolescents with ABI. METHODS: A scoping review. RESULTS: A search conducted using OVID and PubMed databases yielded 2021 citations with 28 publications meeting the inclusion criteria (six reviews, one expert account, 19 observational and two intervention studies)...
2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28943352/genital-reconstruction-for-the-transgendered-individual
#20
REVIEW
Marta R Bizic, Borko Stojanovic, Miroslav L Djordjevic
INTRODUCTION: Gender dysphoria is defined as one's belief that his/her body does not reflect his/her true "inner" identification of physical sex and requires medical and/or surgical treatment that will alter his/her body to better reflect what he/she believes is his/her true gender. OBJECTIVE: The aim was to describe current surgical techniques available in genital reconstruction for female-to-male (FTM) and male-to-female (MTF) transgender patients. STUDY DESIGN: We reviewed recently published papers concerning the most common procedures in genital reconstruction in FTM transgenders and in MTF transgenders...
October 2017: Journal of Pediatric Urology
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