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https://www.readbyqxmd.com/read/28427778/factors-associated-with-delayed-presentation-and-misdiagnosis-of-testicular-torsion-a-case-control-study
#1
Christopher E Bayne, Jeffrey Villanueva, Tanya D Davis, Hans G Pohl, H G Rushton
We identified factors associated with delay in presentation and misdiagnosis of testicular torsion. Compared with acute cases, delayed presentations were more likely to report isolated abdominal pain, developmental disorders, and history of recent genital trauma. Failure to perform a genitourinary examination or scrotal imaging was associated with misdiagnosis.
April 18, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28419509/automatic-diagnosis-of-vulvovaginal-candidiasis-from-pap-smear-images
#2
M Momenzadeh, M Sehhati, A Mehri Dehnavi, A Talebi, H Rabbani
Vulvovaginal candidiasis (VVC) is the most common genital infections that are seen every day in clinics. This infection is due to excessive growth of Candida that are normally present in the vagina in small numbers. Diagnosis of VVC is routinely done by direct microscopy of Pap smear samples and searching for the Candida in the Pap smear glass slides. This manual method is subjective, time consuming, labour-intensive and tedious. This study presents a computer-aided diagnostic (CAD) method to improve human diagnosis of VVC...
April 17, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28414684/who-shot-the-cannonballs-extensive-lung-metastases-in-a-39-year-old-man
#3
D Sommerhalder, J Blondin
CASE: A 39 year-old man presented to the emergency department complaining of a cough of 2 months in duration. He also complained of weight loss of 20 pounds in two months and night sweats over the same period. An x-ray of the chest was performed and revealed innumerable lung nodules and masses. Computed tomography of the chest and abdomen were subsequently performed which confirmed the masses, but imaging did not reveal an obvious primary source. A testicular exam was performed but no obvious abnormalities were noted...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28402260/dna-plasmid-vaccine-carrying-chlamydia-trachomatis-ct-major-outer-membrane-and-human-papillomavirus-16l2-proteins-for-anti-ct-infection
#4
Ledan Wang, Yiqi Cai, Yirong Xiong, Wangqi Du, Danwei Cen, Chanqiong Zhang, Yiling Song, Shanli Zhu, Xiangyang Xue, Lifang Zhang
Chlamydia trachomatis (Ct) is one of the most frequently encountered sexual infection all over the world, yielding tremendous reproductive problems (e.g. infertility and ectopic pregnancy) in the women. This work described the design of a plasmid vaccine that protect mice from Ct infection, and reduce productive tract damage by generating effective antibody and cytotoxic T cell immunity. The vaccine, s was composed of MOMP multi-epitope and HPV16L2 genes carried in pcDNA plasmid (i.e. pcDNA3.1/MOMP/HPV16L)...
March 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28397653/-genital-actinomycosis-and-pelvic-abscesses-in-a-woman-with-a-13-year-old-intrauterine-device
#5
Anne Bank Boisen, Eva Bjerre Ostenfeldt, Lise Tornvig Erikstrup, Bjørn Bay
A 55-year-old woman who had had the same intrauterine device (IUD) for 13 years was referred to the gynaecology outpatient clinic due to constitutional symptoms, abdominal pain and vaginal discharge. Diagnostic imaging showed multiple pelvic abscesses, and severe chronic endometritis with Actinomyces was found in an endometrial biopsy. The patient underwent surgical drainage of the accessible abscesses and started long-term antibiotic treatment. This case report illustrates that actinomycosis is an important differential diagnosis in symptomatic women with IUD and suspected gynaecologic malignancy...
March 27, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28389178/ultrasound-diagnosis-of-fetal-hypospadias-accuracy-and-outcomes
#6
Yan Epelboym, Carlos Estrada, Judy Estroff
OBJECTIVES: The purpose of this study was to assess the positive predictive value of a prenatal ultrasound diagnosis of hypospadias when compared with postnatal diagnosis based on physical exam. METHODS: We retrospectively identified all pregnant women between 2004 and 2014 who were either referred to our fetal care center carrying a fetus with an ultrasound diagnosis of possible hypospadias or who had a new diagnosis of hypospadias after imaging in our center. RESULTS: A total of 32 cases of possible hypospadias were identified, with our fetal center ultrasound suggesting hypospadias in 25 of the 32 cases (78%)...
March 24, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28382212/altered-spinal-cord-activity-during-sexual-stimulation-in-women-with-sci-a-pilot-fmri-study
#7
Marcalee Alexander, Natalie Kozyrev, Chase R Figley, J Scott Richards
INTRODUCTION: The objective of this study was to assess the feasibility of the use of functional magnetic resonance imaging (fMRI) to evaluate the spinal activation during sexual response of the thoracic, lumbar and sacral spinal cord. MATERIALS AND METHODS: This is a laboratory-based pilot study in human females at a University-based medical center in the United States. In three healthy spinal cord injury (SCI) females, spinal cord activations during sexual audiovisual stimulation (alone), genital self-stimulation (alone) and simultaneous audiovisual and genital self-stimulation (combined) were assessed and then compared with each subjects' remaining sensory and motor function...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28379959/unraveling-chagas-disease-transmission-through-the-oral-route-gateways-to-trypanosoma-cruzi-infection-and-target-tissues
#8
Danielle Silva-Dos-Santos, Juliana Barreto-de-Albuquerque, Bárbara Guerra, Otacilio C Moreira, Luiz Ricardo Berbert, Mariana Tavares Ramos, Barbara Angelica S Mascarenhas, Constança Britto, Alexandre Morrot, Déa M Serra Villa-Verde, Luciana Ribeiro Garzoni, Wilson Savino, Vinícius Cotta-de-Almeida, Juliana de Meis
Oral transmission of Trypanosoma cruzi, the causative agent of Chagas disease, is the most important route of infection in Brazilian Amazon and Venezuela. Other South American countries have also reported outbreaks associated with food consumption. A recent study showed the importance of parasite contact with oral cavity to induce a highly severe acute disease in mice. However, it remains uncertain the primary site of parasite entry and multiplication due to an oral infection. Here, we evaluated the presence of T...
April 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28366591/quality-of-life-and-patient-satisfaction-following-male-to-female-sex-reassignment-surgery
#9
Nikolaos A Papadopulos, Jean-Daniel Lellé, Dmitry Zavlin, Peter Herschbach, Gerhard Henrich, Laszlo Kovacs, Benjamin Ehrenberger, Anna-Katharina Kluger, Hans-Guenther Machens, Juergen Schaff
BACKGROUND: Surveys on quality of life (QOL) of male-to-female (MTF) transsexuals have found low QOL scores before and increased satisfaction scores after sex-reassignment surgery (SRS). To our knowledge, many of them lack standardized questionnaires and comparisons with normative data to evaluate different vaginoplasty techniques. AIM: To analyze patient satisfaction and QOL after SRS. METHODS: Forty-seven patients participated in this study...
March 30, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28340341/tridimensional-visualization-and-analysis-of-early-human-development
#10
Morgane Belle, David Godefroy, Gérard Couly, Samuel A Malone, Francis Collier, Paolo Giacobini, Alain Chédotal
Generating a precise cellular and molecular cartography of the human embryo is essential to our understanding of the mechanisms of organogenesis in normal and pathological conditions. Here, we have combined whole-mount immunostaining, 3DISCO clearing, and light-sheet imaging to start building a 3D cellular map of the human development during the first trimester of gestation. We provide high-resolution 3D images of the developing peripheral nervous, muscular, vascular, cardiopulmonary, and urogenital systems...
March 23, 2017: Cell
https://www.readbyqxmd.com/read/28325966/sulawesifulvius-thailandicus-a-new-species-of-the-genus-sulawesifulvius-gorczyca-ch%C3%A3-rot-%C3%A5-tys-from-thailand-hemiptera-heteroptera-miridae-cylapinae
#11
Andrzej Wolski, Tomohide Yasunaga, Jacek Gorczyca, Aleksander Herczek
A new species of the genus Sulawesifulvius, Sulawesifulvius thailandicus Wolski, Yasunaga & Gorczyca, sp. n., is described from Thailand. The present finding also represents the first distribution record in Indochina for the genus. Color adult habitus images for Sulawesifulvius thailandicus and Sulawesifulvius schuhi (type species of the genus), male genital drawings of Sulawesifulvius thailandicus, and scanning electron micrographs of selected structures of Sulawesifulvius schuhi and Sulawesifulvius thailandicus are provided...
2017: ZooKeys
https://www.readbyqxmd.com/read/28325390/patterns-of-distribution-of-giant-congenital-melanocytic-nevi-gcmn-the-6b-rule
#12
Vanessa P Martins da Silva, Ashfaq Marghoob, Ramon Pigem, Cristina Carrera, Paula Aguilera, Joan A Puig-Butillé, Susana Puig, Josep Malvehy
BACKGROUND: Garment-related terms have been used to describe the pattern of distribution of giant congenital melanocytic nevi (GCMN). OBJECTIVE: We sought to describe patterns of distribution of GCMN and propose a classification scheme. METHODS: Photographic records of patients with GCMN from the Hospital Clinic of Barcelona were analyzed and a classification based on observed GCMN distribution patterns was created. The classification was independently applied by 8 observers to cases found in the literature...
April 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28324630/morphological-and-neurochemical-differences-in-peptidergic-nerve-fibers-of-the-mouse-vagina
#13
Christine M Barry, Esther Ji, Harman Sharma, Lara Beukes, Patricia I Vilimas, Yvette C DeGraaf, Dusan Matusica, Rainer V Haberberger
The vagina is innervated by a complex arrangement of sensory, sympathetic, and parasympathetic nerve fibers that contain classical transmitters plus an array of neuropeptides and enzymes known to regulate diverse processes including blood flow and nociception. The neurochemical characteristics and distributions of peptide-containing nerves in the mouse vagina are unknown. This study used multiple labeling immunohistochemistry, confocal maging and analysis to investigate the presence and colocalization of the peptides vasoactive intestinal polypeptide (VIP), calcitonin-gene related peptide (CGRP), substance P (SP), neuropeptide tyrosine (NPY), and the nitric oxide synthesizing enzyme neuronal nitric oxide synthase (nNOS) in nerve fibers of the murine vaginal wall...
March 21, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28319558/effects-of-medical-interventions-on-gender-dysphoria-and-body-image-a-follow-up-study
#14
Tim C van de Grift, Els Elaut, Susanne C Cerwenka, Peggy T Cohen-Kettenis, Griet De Cuypere, Hertha Richter-Appelt, Baudewijntje P C Kreukels
OBJECTIVES: The aim of the European Network for the Investigation of Gender Incongruence is to investigate the status of all individuals who had applied for gender confirming interventions from 2007 until 2009, irrespective of whether they received treatment. The current article describes the study protocol, the effect of medical treatment on gender dysphoria and body image, and the predictive value of (pre)treatment factors on post-treatment outcomes. METHODS: Data were collected on medical interventions, transition status, gender dysphoria (Utrecht Gender Dysphoria Scale), and body image (Body Image Scale for Transsexuals)...
March 18, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28314908/anatomy-and-aesthetics-of-the-labia-minora-the-ideal-vulva
#15
REVIEW
C Clerico, A Lari, A Mojallal, F Boucher
Female genital cosmetic surgery is becoming more and more widespread both in the field of plastic and gynaecological surgery. The increased demand for vulvar surgery is spurred by the belief that the vulva is abnormal in appearance. What is normal in terms of labial anatomy? Labia minora enlargement or hypertrophy remains a clinical diagnosis which is poorly defined as it could be considered a variation of the normal anatomy. Enlarged labia minora can cause functional, aesthetic and psychosocial problems. In reality, given the wide variety of vulvar morphology among people, it is a very subjective issue to define the "normal" vulva...
March 10, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28299220/spontaneous-regression-of-uterine-arteriovenous-malformations-with-conservative-management
#16
Keiko Mekaru, Sugiko Oishi, Kozue Akamine, Chiaki Heshiki, Yoichi Aoki
Uterine arteriovenous malformation (AVM) can cause massive hemorrhage and is often treated with uterine artery embolization (UAE), which may lead to ovarian insufficiency. Thus, avoiding UAE should be considered, particularly in women undergoing fertility treatments. We present three women diagnosed with postmiscarriage AVM on color Doppler by transvaginal ultrasound imaging. They had no genital bleeding and a small mass, measuring 16-22 mm. If estradiol was >300 pg/mL when AVM was diagnosed, then a gonadotropin-releasing hormone agonist was administered...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28295555/evaluation-of-positron-emission-tomography-imaging-to-detect-lymph-node-metastases-in-patients-with-extramammary-paget-s-disease
#17
Masao Fujiwara, Takahiro Suzuki, Ayumi Senoo, Hidekazu Fukamizu, Yoshiki Tokura
Patients with extramammary Paget's disease (EMPD) have a relatively good prognosis, when spread of the tumor cells is limited to the epidermis. However, invasive EMPD has a poor prognosis, when the patients have regional lymph node metastasis. Detection of nodal metastasis is thus mandatory to manage EMPD. To evaluate the (18) F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging to assess lymph node metastasis, 15 patients with histologically proven primary EMPD were enrolled in this study. All patients underwent whole-body PET prior to sentinel lymph node biopsy (SLNB)...
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28288664/injured-bodies-damaged-lives-experiences-and-narratives-of-kenyan-women-with-obstetric-fistula-and-female-genital-mutilation-cutting
#18
Lillian Mwanri, Glory Joy Gatwiri
BACKGROUND: It is well acknowledged that Female Genital Mutilation/Cutting (FGM/C/C) leads to medical, psychological and sociocultural sequels. Over 200 million cases of FGM/C exist globally, and in Kenya alone, a total of 12,418,000 (28%) of women have undergone FGM/C, making the practice not only a significant national, but also a global health catastrophe. FGM/C is rooted in patriarchal and traditional cultures as a communal experience signifying a transition from girlhood to womanhood...
March 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28283284/mri-in-the-evaluation-of-obstructive-reproductive-tract-anomalies-in-paediatric-patients
#19
H Zhang, H Qu, G Ning, B Cheng, F Jia, X Li, X Chen
AIM: To outline the anatomical variations of obstructive reproductive tract anomalies (ORTA) using magnetic resonance imaging (MRI) and its role in preoperative evaluation. MATERIALS AND METHODS: MRI and treatment of 21 paediatric patients with ORTA were reviewed and analysed. MRI findings were correlated with ultrasound and surgical findings. RESULTS: Patients presented in two distinct ways: primary amenorrhoea with cyclic pelvic pain, or progressive dysmenorrhoea...
March 7, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28279890/the-impact-of-genital-self-image-on-sexual-function-in-women-with-pelvic-floor-disorders
#20
Jonathan E Handelzalts, Tal Yaakobi, Sigal Levy, Yoav Peled, Arnon Wiznitzer, Haim Krissi
OBJECTIVE: There is conflicting evidence regarding the impact of urinary incontinence and pelvic organ prolapse on overall sexual function. However, psychological variables thought to be associated with sexual function, have not been fully explored. We assessed the sexual functioning of women with pelvic floor disorders while measuring for psychological factors such as distress and genital self-image. STUDY DESIGN: In a cross-sectional study, 155 women in an urogynecology outpatient clinic of a tertiary health center completed a demographic questionnaire, the Brief Symptom Index-18 (BSI-18), Pelvic Floor Distress Inventory-20 (PFDI-20), Genital Self-Image Scale-20 (GSIS-20) and the Female Sexual Function Index (FSFI)...
February 28, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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