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https://www.readbyqxmd.com/read/28340341/tridimensional-visualization-and-analysis-of-early-human-development
#1
Morgane Belle, David Godefroy, Gérard Couly, Samuel A Malone, Francis Collier, Paolo Giacobini, Alain Chédotal
Generating a precise cellular and molecular cartography of the human embryo is essential to our understanding of the mechanisms of organogenesis in normal and pathological conditions. Here, we have combined whole-mount immunostaining, 3DISCO clearing, and light-sheet imaging to start building a 3D cellular map of the human development during the first trimester of gestation. We provide high-resolution 3D images of the developing peripheral nervous, muscular, vascular, cardiopulmonary, and urogenital systems...
March 23, 2017: Cell
https://www.readbyqxmd.com/read/28325966/sulawesifulvius-thailandicus-a-new-species-of-the-genus-sulawesifulvius-gorczyca-ch%C3%A3-rot-%C3%A5-tys-from-thailand-hemiptera-heteroptera-miridae-cylapinae
#2
Andrzej Wolski, Tomohide Yasunaga, Jacek Gorczyca, Aleksander Herczek
A new species of the genus Sulawesifulvius, Sulawesifulvius thailandicus Wolski, Yasunaga & Gorczyca, sp. n., is described from Thailand. The present finding also represents the first distribution record in Indochina for the genus. Color adult habitus images for Sulawesifulvius thailandicus and Sulawesifulvius schuhi (type species of the genus), male genital drawings of Sulawesifulvius thailandicus, and scanning electron micrographs of selected structures of Sulawesifulvius schuhi and Sulawesifulvius thailandicus are provided...
2017: ZooKeys
https://www.readbyqxmd.com/read/28325390/patterns-of-distribution-of-giant-congenital-melanocytic-nevi-gcmn-the-6b-rule
#3
Vanessa P Martins da Silva, Ashfaq Marghoob, Ramon Pigem, Cristina Carrera, Paula Aguilera, Joan A Puig-Butillé, Susana Puig, Josep Malvehy
BACKGROUND: Garment-related terms have been used to describe the pattern of distribution of giant congenital melanocytic nevi (GCMN). OBJECTIVE: We sought to describe patterns of distribution of GCMN and propose a classification scheme. METHODS: Photographic records of patients with GCMN from the Hospital Clinic of Barcelona were analyzed and a classification based on observed GCMN distribution patterns was created. The classification was independently applied by 8 observers to cases found in the literature...
April 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28324630/morphological-and-neurochemical-differences-in-peptidergic-nerve-fibres-of-the-mouse-vagina
#4
Christine Barry, Esther Ji, Harman Sharma, Lara Beukes, Pat Vilimas, Yvette DeGraaf, Dusan Matusica, Rainer V Haberberger
The vagina is innervated by a complex arrangement of sensory, sympathetic and parasympathetic nerve fibres that contain classical transmitters plus an array of neuropeptides and enzymes known to regulate diverse processes including blood flow and nociception. The neurochemical characteristics and distributions of peptide-containing nerves in the mouse vagina are unknown. This study used multiple labelling immunohistochemistry, confocal imaging and analysis to investigate the presence and colocalization of the peptides vasoactive intestinal polypeptide (VIP), calcitonin-gene related peptide (CGRP), substance P (SP), neuropeptide tyrosine (NPY) and the nitric oxide synthesizing enzyme neuronal nitric oxide synthase (nNOS) in nerve fibres of the murine vaginal wall...
March 21, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28319558/effects-of-medical-interventions-on-gender-dysphoria-and-body-image-a-follow-up-study
#5
Tim C van de Grift, Els Elaut, Susanne C Cerwenka, Peggy T Cohen-Kettenis, Griet De Cuypere, Hertha Richter-Appelt, Baudewijntje P C Kreukels
OBJECTIVES: The aim of the European Network for the Investigation of Gender Incongruence is to investigate the status of all individuals who had applied for gender confirming interventions from 2007 until 2009, irrespective of whether they received treatment. The current article describes the study protocol, the effect of medical treatment on gender dysphoria and body image, and the predictive value of (pre)treatment factors on post-treatment outcomes. METHODS: Data were collected on medical interventions, transition status, gender dysphoria (Utrecht Gender Dysphoria Scale), and body image (Body Image Scale for Transsexuals)...
March 18, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28314908/anatomy-and-aesthetics-of-the-labia-minora-the-ideal-vulva
#6
REVIEW
C Clerico, A Larry, A Mojallal, F Boucher
Female genital cosmetic surgery is becoming more and more widespread both in the field of plastic and gynaecological surgery. The increased demand for vulvar surgery is spurred by the belief that the vulva is abnormal in appearance. What is normal in terms of labial anatomy? Labia minora enlargement or hypertrophy remains a clinical diagnosis which is poorly defined as it could be considered a variation of the normal anatomy. Enlarged labia minora can cause functional, aesthetic and psychosocial problems. In reality, given the wide variety of vulvar morphology among people, it is a very subjective issue to define the "normal" vulva...
March 10, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28299220/spontaneous-regression-of-uterine-arteriovenous-malformations-with-conservative-management
#7
Keiko Mekaru, Sugiko Oishi, Kozue Akamine, Chiaki Heshiki, Yoichi Aoki
Uterine arteriovenous malformation (AVM) can cause massive hemorrhage and is often treated with uterine artery embolization (UAE), which may lead to ovarian insufficiency. Thus, avoiding UAE should be considered, particularly in women undergoing fertility treatments. We present three women diagnosed with postmiscarriage AVM on color Doppler by transvaginal ultrasound imaging. They had no genital bleeding and a small mass, measuring 16-22 mm. If estradiol was >300 pg/mL when AVM was diagnosed, then a gonadotropin-releasing hormone agonist was administered...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28295555/evaluation-of-positron-emission-tomography-imaging-to-detect-lymph-node-metastases-in-patients-with-extramammary-paget-s-disease
#8
Masao Fujiwara, Takahiro Suzuki, Ayumi Senoo, Hidekazu Fukamizu, Yoshiki Tokura
Patients with extramammary Paget's disease (EMPD) have a relatively good prognosis, when spread of the tumor cells is limited to the epidermis. However, invasive EMPD has a poor prognosis, when the patients have regional lymph node metastasis. Detection of nodal metastasis is thus mandatory to manage EMPD. To evaluate the (18) F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging to assess lymph node metastasis, 15 patients with histologically proven primary EMPD were enrolled in this study. All patients underwent whole-body PET prior to sentinel lymph node biopsy (SLNB)...
March 11, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28288664/injured-bodies-damaged-lives-experiences-and-narratives-of-kenyan-women-with-obstetric-fistula-and-female-genital-mutilation-cutting
#9
Lillian Mwanri, Glory Joy Gatwiri
BACKGROUND: It is well acknowledged that Female Genital Mutilation/Cutting (FGM/C/C) leads to medical, psychological and sociocultural sequels. Over 200 million cases of FGM/C exist globally, and in Kenya alone, a total of 12,418,000 (28%) of women have undergone FGM/C, making the practice not only a significant national, but also a global health catastrophe. FGM/C is rooted in patriarchal and traditional cultures as a communal experience signifying a transition from girlhood to womanhood...
March 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28283284/mri-in-the-evaluation-of-obstructive-reproductive-tract-anomalies-in-paediatric-patients
#10
H Zhang, H Qu, G Ning, B Cheng, F Jia, X Li, X Chen
AIM: To outline the anatomical variations of obstructive reproductive tract anomalies (ORTA) using magnetic resonance imaging (MRI) and its role in preoperative evaluation. MATERIALS AND METHODS: MRI and treatment of 21 paediatric patients with ORTA were reviewed and analysed. MRI findings were correlated with ultrasound and surgical findings. RESULTS: Patients presented in two distinct ways: primary amenorrhoea with cyclic pelvic pain, or progressive dysmenorrhoea...
March 7, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28279890/the-impact-of-genital-self-image-on-sexual-function-in-women-with-pelvic-floor-disorders
#11
Jonathan E Handelzalts, Tal Yaakobi, Sigal Levy, Yoav Peled, Arnon Wiznitzer, Haim Krissi
OBJECTIVE: There is conflicting evidence regarding the impact of urinary incontinence and pelvic organ prolapse on overall sexual function. However, psychological variables thought to be associated with sexual function, have not been fully explored. We assessed the sexual functioning of women with pelvic floor disorders while measuring for psychological factors such as distress and genital self-image. STUDY DESIGN: In a cross-sectional study, 155 women in an urogynecology outpatient clinic of a tertiary health center completed a demographic questionnaire, the Brief Symptom Index-18 (BSI-18), Pelvic Floor Distress Inventory-20 (PFDI-20), Genital Self-Image Scale-20 (GSIS-20) and the Female Sexual Function Index (FSFI)...
February 28, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28274598/sexual-life-of-women-with-mayer-rokitansky-k%C3%A3-ster-hauser-syndrome-after-laparoscopic-vecchietti-vaginoplasty
#12
Zlatko Pastor, Jiří Froněk, Marta Nováčková, Roman Chmel
INTRODUCTION: Adequate anatomic and physiologic functions of the genitalia are fundamental prerequisites for sexual well-being and reproduction. Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) compromises female sexual life and makes reproduction impossible. AIM: To assess the psychosexual effect of vaginal reconstruction using the laparoscopic Vecchietti technique in patients with MRKHS. METHODS: Forty-two patients with MRKHS who underwent laparoscopic Vecchietti vaginoplasty were included...
March 5, 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28257917/transperineal-ultrasound-as-a-tool-to-plan-surgical-strategies-in-pediatric-urology-back-to-the-future
#13
Lisieux Eyer de Jesus, T Fazecas, B G Ribeiro, S Dekermacher
OBJECTIVE: To demonstrate the usefulness and advantages of transperineal ultrasound (TPUS) on planning the surgical tactics to treat childhood pelviperineal disease (CPPD). METHODS: A cohort of CPPD is reviewed to provide a pictorial review of TPUS as imaging method variety of CPPD. Other imaging methods are compared with TPUS. RESULTS: TPUS studies of patients showing different conditions on the spectrum of pelviperineal malformation are shown in detail (pictorial review, graphically shown-see figures in the article and as supplementary material), highlighting the advantages of the method and comparing TPUS findings with other imaging techniques...
February 28, 2017: Urology
https://www.readbyqxmd.com/read/28256903/mr-imaging-in-patients-with-male-to-female-sex-reassignment-surgery-postoperative-anatomy-and-complications
#14
Michele Bertolotto, Giovanni Liguori, Stefano Bucci, Mariano Iannelli, Francesca Vedovo, Nicola Pavan, Carlo Trombetta, Lorenzo E Derchi
OBJECTIVE: To investigate the role of MRI in the evaluation of both the new female anatomy and complications in male-to-female sex reassignment surgery (MtF-SRS). METHODS: 71 consecutive patients with MtF-SRS had 74 MRI [age range, 21-63 years; mean (±standard deviation) age, 36 ± 10 years; median age, 37 years]. In 47 patients, MRI was performed to rule out early post-operative complications after gender conversion (n = 40), vaginoplasty (n = 6) or remodelling of the labia majora (n = 1)...
April 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28243497/dermoscopic-and-confocal-features-of-an-axillary-special-site-nevus
#15
Riana Dutt, Harold S Rabinovitz, Rajendra Singh, Alon Scope
"Nevi of special sites" is a term that denotes melanocytic nevi presenting in specific anatomic locations including the scalp, genital area, flexural sites, and acral sites [1]. Nevi from these anatomic sites display at times histopathologic features that may lead the reading pathologist to recommend re-excision of these benign nevi. Reflectance confocal microscopy (RCM) is a noninvasive imaging tool that allows for visualization of epidermal, dermal-epidermal junctional (DEJ), and superficial dermal tissue structures at cellular level resolution...
January 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28240585/fibromyalgia-prevalence-and-associated-factors-in-primary-sj%C3%A3-gren-s-syndrome-patients-in-a-large-cohort-from-the-spanish-society-of-rheumatology-registry-sjogrenser
#16
Vicenç Torrente-Segarra, Hèctor Corominas, Carlos Sánchez-Piedra, Mónica Fernández-Castro, José Luis Andreu, Víctor Manuel Martínez-Taboada, Alejandro Olivé, José Rosas, Fernando Sánchez-Alonso
OBJECTIVES: To assess fibromyalgia (FM) prevalence in a large cohort of primary Sjögren's syndrome patients (pSS) from a National Database. METHODS: Data included in the national retrospective register of pSS patients of the Spanish Society of Rheumatology (SJOGRENSER) were analysed. RESULTS: 437 pSS patients were included and a 14.6% of FM prevalence was found. FM-pSS patients significantly showed more constitutional, fatigue and arthralgia symptoms, splenomegaly, genital, skin and ear involvement and dyslipidaemia (p<0...
February 24, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28238679/how-does-paying-attention-improve-sexual-functioning-in-women-a%C3%A2-review-of-mechanisms
#17
REVIEW
Nikita Arora, Lori A Brotto
INTRODUCTION: Female sexual dysfunction (FSD), consisting of a constellation of distressing sexual symptoms, is highly prevalent worldwide. Given the central role played by psychological factors in the development of FSD, psychologically and in particular mindfulness-based interventions have arisen as potential treatment options for women. Although mindfulness-based interventions have been evaluated in samples of women with gynecologic cancer; a history of sexual abuse; multiple sclerosis; and spinal cord injury; and provoked vestibulodynia, the mechanisms by which mindfulness leads to improvements in sexual functioning are largely unstudied...
February 23, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28228879/zinner-syndrome-diagnosed-by-magnetic-resonance-imaging-and-computed-tomography-role-of-imaging-to-identify-and-evaluate-the-uncommon-variation-in-development-of-the-male-genital-tract
#18
V Fiaschetti, L Greco, V Giuricin, D De Vivo, E Di Caprera, R Di Trapano, F Castellani, R Floris
Seminal vesicle cysts are a very rare condition and its often associated with ipsilateral renal agenesis. The diagnosis of seminal vesicle cysts may be delayed or missed because of the non-specific symptoms of this condition. This article reports a triad of right renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction (Zinner syndrome) in a 56 years old man.
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28204933/a-systematic-review-of-patient-reported-outcome-measures-following-transsexual-surgery
#19
REVIEW
M Barone, A Cogliandro, N Di Stefano, V Tambone, P Persichetti
BACKGROUND: The aims of our study were to identify studies that evaluated patient satisfaction after transsexual surgery, analyze existing questionnaires, and summarize their development, psychometric properties, and content. METHODS: A systematic review of the English-language literature was performed. Patient-reported outcome measures designed to assess patient satisfaction and quality of life following transsexual surgery were identified. Qualifying instruments were assessed for content and adherence to international guidelines for development and validation...
February 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28194515/genital-and-reproductive-organ-complications-of-crohn-disease-technical-considerations-as-it-relates-to-perianal-disease-imaging-features-and-implications-on-management
#20
REVIEW
Steven Kammann, Christine Menias, Amy Hara, Mariam Moshiri, Cary Siegel, Bashar Safar, Steven Brandes, Akram Shaaban, Kumar Sandrasegaran
OBJECTIVE: A relatively large proportion of patients with Crohn disease (CD) develop complications including abscess formation, stricture, and penetrating disease. A subset of patients will have genital and reproductive organ involvement of CD, resulting in significant morbidity. These special circumstances create unique management challenges that must be tailored to the activity, location, and extent of disease. Familiarity with the epidemiology, pathogenesis, imaging features, and treatment strategies for patients with genital CD can aid imaging diagnoses and guide appropriate patient management...
February 13, 2017: Abdominal Radiology
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