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https://www.readbyqxmd.com/read/28774605/concentrations-of-disinfection-by-products-in-swimming-pool-following-modifications-of-the-water-treatment-process-an-exploratory-study
#1
Robert Tardif, Manuel Rodriguez, Cyril Catto, Ginette Charest-Tardif, Sabrina Simard
The formation and concentration of disinfection by-products (DBPs) in pool water and the ambient air vary according to the type of water treatment process used. This exploratory study was aimed at investigating the short-term impact of modifications of the water treatment process on traditional DBP levels (e.g., trihalomethanes (THMs), chloramines) and emerging DBPs (e.g., Halonitromethanes, Haloketones, NDMA) in swimming pool water and/or air. A sampling program was carried to understand the impact of the following changes made successively to the standard water treatment process: activation of ultraviolet (UV) photoreactor, halt of air stripping with continuation of air extraction from the buffer tank, halt of air stripping and suppression of air extraction from the buffer tank, suppression of the polyaluminium silicate sulfate (PASS) coagulant...
August 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28764844/biliopancreatic-diversion-with-duodenal-switch-leads-to-better-postprandial-glucose-level-and-beta-cell-function-than-sleeve-gastrectomy-in-individuals-with-type-2-diabetes-very-early-after-surgery
#2
Andréanne Michaud, Thomas Grenier-Larouche, Dominique Caron-Dorval, Simon Marceau, Laurent Biertho, Serge Simard, Denis Richard, André Tchernof, André C Carpentier
OBJECTIVE: The aim of this study was to compare the short-term effect of sleeve gastrectomy (SG) and biliopancreatic diversion with duodenal switch (DS) in order to determine if exclusion of the upper gastrointestinal tract confers greater metabolic improvement, independent of weight loss. METHODS: Standard meals were administered before and on day 3 and 4 after SG to assess insulin sensitivity, β-cell function and gastrointestinal hormone responses in matched normoglycemic (NG) and type 2 diabetes (T2D) participants...
September 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28755464/acetyl-coa-carboxylase-overexpression-in-herbicide-resistant-large-crabgrass-digitaria-sanguinalis
#3
Martin Laforest, Brahim Soufiane, Marie-Josée Simard, Kristen Obeid, Eric Page, Robert E Nurse
BACKGROUND: The occurrence of herbicide resistant weed biotypes is increasing and this report of an Acetyl-CoA Carboxylase (ACCase) inhibitor resistant Digitaria sanguinalis L. Scop. from Southwestern Ontario is another example. The identified weed escaped control in an onion and carrot rotation where graminicides where used for several consecutive years. Our goal was to characterise the level and mechanism of resistance of the biotype. RESULTS: The biotype was resistant to all five ACCase inhibitor herbicides tested...
July 29, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28755462/exploring-the-screening-capacity-of-the-fear-of-cancer-recurrence-inventory-short-form-for-clinical-levels-of-fear-of-cancer-recurrence
#4
Joanna E Fardell, Georden Jones, Allan Ben Smith, Sophie Lebel, Belinda Thewes, Daniel Costa, Kerry Tiller, Sébastien Simard, Andrea Feldstain, Sara Beattie, Megan McCallum, Phyllis Butow
OBJECTIVE: Fear of cancer recurrence (FCR) is a common concern among cancer survivors. Identifying survivors with clinically significant FCR requires validated screening measures and clinical cut-offs. We evaluated the Fear of Cancer Recurrence Inventory-Short Form (FCRI-SF) clinical cut-off in two samples. METHODS: Level of FCR in study 1 participants (from an Australian randomised controlled trial: ConquerFear) was compared to FCRI-SF scores. Based on a biopsychosocial interview, clinicians rated participants as having non-clinical, sub-clinical, or clinical FCR...
July 28, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28754054/help-me-help-me
#5
Joyce Simard
Disruptive vocalization and resisting personal care is a problem for staff in most skilled nursing facilities. Often these behaviors result in the resident being treated with antipsychotics. The Namaste Care program which takes place in a calm environment and offers a loving touch approach to care, has been successful in eliminating these behaviors. The room or space where Namaste Care takes place is as free from disruption as possible and as the resident is welcomed into the room, the calming music and scent of lavender surrounds them...
October 2017: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/28754046/using-the-ecological-framework-to-identify-barriers-and-enablers-to-implementing-namaste-care-in-canada-s-long-term-care-system
#6
Paulette V Hunter, Sharon Kaasalainen, Katherine A Froggatt, Jenny Ploeg, Lisa Dolovich, Joyce Simard, Mahvash Salsali
BACKGROUND: Higher acuity of care at the time of admission to long-term care (LTC) is resulting in a shorter period to time of death, yet most LTC homes in Canada do not have formalized approaches to palliative care. Namaste Care is a palliative care approach specifically tailored to persons with advanced cognitive impairment who are living in LTC. The purpose of this study was to employ the ecological framework to identify barriers and enablers to an implementation of Namaste Care. METHODS: Six group interviews were conducted with families, unlicensed staff, and licensed staff at two Canadian LTC homes that were planning to implement Namaste Care...
October 2017: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/28754045/implementing-the-namaste-care-program-for-residents-with-advanced-dementia-exploring-the-perceptions-of-families-and-staff-in-uk-care-homes
#7
Min Stacpoole, Jo Hockley, Amanda Thompsell, Joyce Simard, Ladislav Volicer
BACKGROUND: Increasing numbers of older people with advanced dementia are cared for in care homes. No cure is available, so research focused on improving quality of life and quality of care for people with dementia is needed to support them to live and die well. The Namaste Care programme is a multi-dimensional care program with sensory, psycho-social and spiritual components intended to enhance quality of life and quality of care for people with advanced dementia. The aim of the study was to establish whether the Namaste Care program can be implemented in UK care homes; and what effect Namaste Care has on the quality of life of residents with advanced dementia, their families and staff...
October 2017: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/28751290/myoadenylate-deaminase-deficiency-a-frequent-cause-of-muscle-pain-a-case-detected-by-exercise-testing
#8
Lydie Lim, Maeva Palayer, Antoine Bruneau, Franck Letournel, Cédric Le Maréchal, Gilles Simard, Pascal Reynier, Chadi Homedan, Aleksandra Nadaj-Pakleza
Myoadenylate deaminase deficit (MAD, MIM#615511) is the most common cause of metabolic myopathies with an estimated prevalence of 1-2% in the general population. We report the case of a 39-year-old man suffering from severe skeletal muscle pain that had developed gradually for 4 years. A moderate increase in creatine kinase (CK) was the only biological sign observed. This study takes a closer look at a common but poorly known pathology and highlights the interest of the dynamic metabolic investigations carried out during exercise stress test with a cycle ergometer...
August 1, 2017: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/28747349/outcomes-associated-with-a-pediatric-clinical-diabetes-network-in-ontario-a-population-based-time-trend-analysis
#9
Meranda Nakhla, Elham Rahme, Marc Simard, Astrid Guttmann
BACKGROUND: The Network of Ontario Pediatric Diabetes Programs was implemented in 2001. The objective of this study was to determine whether implementation of the network was associated with a decrease in the risk of acute diabetes-related complications and a reduction in the socioeconomic and geographic disparities in these outcomes. METHODS: We conducted a population-based time trend analysis of children (< 18 yr) with diabetes using health administrative databases in Ontario from 1996 to 2011...
July 24, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28729711/an-ecological-and-digital-epidemiology-analysis-on-the-role-of-human-behavior-on-the-2014-chikungunya-outbreak-in-martinique
#10
Benjamin Roche, Béatrice Gaillard, Lucas Léger, Renélise Pélagie-Moutenda, Thomas Sochacki, Bernard Cazelles, Martine Ledrans, Alain Blateau, Didier Fontenille, Manuel Etienne, Frédéric Simard, Marcel Salathé, André Yébakima
Understanding the spatio-temporal dynamics of endemic infections is of critical importance for a deeper understanding of pathogen transmission, and for the design of more efficient public health strategies. However, very few studies in this domain have focused on emerging infections, generating a gap of knowledge that hampers epidemiological response planning. Here, we analyze the case of a Chikungunya outbreak that occurred in Martinique in 2014. Using time series estimates from a network of sentinel practitioners covering the entire island, we first analyze the spatio-temporal dynamics and show that the largest city has served as the epicenter of this epidemic...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28726879/o-phthalaldehyde-catalyzed-hydrolysis-of-organophosphinic-amides-and-other-p-double-bond-length-as-m-dash-o-nh-containing-compounds
#11
Bin-Jie Li, Ryan D Simard, André M Beauchemin
Over 50 years ago, Jencks and Gilchrist showed that formaldehyde catalyses the hydrolysis of phosphoramidate through electrophilic activation, induced by covalent attachment to its nitrogen atom. Given our interest in the use of aldehydes as catalysts, this work was revisited to identify a superior catalyst, o-phthalaldehyde, which facilitates hydrolyses of various organophosphorus compounds bearing P([double bond, length as m-dash]O)-NH subunits under mild conditions. Interestingly, chemoselective hydrolysis of the P([double bond, length as m-dash]O)-N bonds could be accomplished in the presence of P([double bond, length as m-dash]O)-OR bonds...
July 20, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28725105/porcine-reproductive-and-respiratory-syndrome-virus-prrsv-in-pig-meat
#12
Philippe Raymond, Christian Bellehumeur, Malliga Nagarajan, Diane Longtin, Alexandra Ferland, Peter Müller, Rachel Bissonnette, Carole Simard
Porcine reproductive and respiratory syndrome, caused by the porcine reproductive and respiratory syndrome virus (PRRSV), is an economically important disease in the swine industry. Previous studies demonstrated the presence of the virus in pig meat and its transmissibility by oral consumption. This study further analyzed the infectivity of PRRSV in commercial pig meat. Fresh bottom meat pieces (n = 1500) randomly selected over a period of 2 y from a pork ham boning plant located in Quebec, Canada, were tested by reverse transcriptase polymerase chain reaction (RT-PCR)...
July 2017: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/28716717/big-gaba-edited-mr-spectroscopy-at-24-research-sites
#13
Mark Mikkelsen, Peter B Barker, Pallab K Bhattacharyya, Maiken K Brix, Pieter F Buur, Kim M Cecil, Kimberly L Chan, David Y-T Chen, Alexander R Craven, Koen Cuypers, Michael Dacko, Niall W Duncan, Ulrike Dydak, David A Edmondson, Gabriele Ende, Lars Ersland, Fei Gao, Ian Greenhouse, Ashley D Harris, Naying He, Stefanie Heba, Nigel Hoggard, Tun-Wei Hsu, Jacobus F A Jansen, Alayar Kangarlu, Thomas Lange, R Marc Lebel, Yan Li, Chien-Yuan E Lin, Jy-Kang Liou, Jiing-Feng Lirng, Feng Liu, Ruoyun Ma, Celine Maes, Marta Moreno-Ortega, Scott O Murray, Sean Noah, Ralph Noeske, Michael D Noseworthy, Georg Oeltzschner, James J Prisciandaro, Nicolaas A J Puts, Timothy P L Roberts, Markus Sack, Napapon Sailasuta, Muhammad G Saleh, Michael-Paul Schallmo, Nicholas Simard, Stephan P Swinnen, Martin Tegenthoff, Peter Truong, Guangbin Wang, Iain D Wilkinson, Hans-Jörg Wittsack, Hongmin Xu, Fuhua Yan, Chencheng Zhang, Vadim Zipunnikov, Helge J Zöllner, Richard A E Edden
Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid (GABA) in the human brain. Its increasing popularity has been aided by improvements in scanner hardware and acquisition methodology, as well as by broader access to pulse sequences that can selectively detect GABA, in particular J-difference spectral editing sequences. Nevertheless, implementations of GABA-edited MRS remain diverse across research sites, making comparisons between studies challenging...
July 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28706586/influence-of-cardiac-nerve-status-on-cardiovascular-regulation-and-cardioprotection
#14
REVIEW
John G Kingma, Denys Simard, Jacques R Rouleau
Neural elements of the intrinsic cardiac nervous system transduce sensory inputs from the heart, blood vessels and other organs to ensure adequate cardiac function on a beat-to-beat basis. This inter-organ crosstalk is critical for normal function of the heart and other organs; derangements within the nervous system hierarchy contribute to pathogenesis of organ dysfunction. The role of intact cardiac nerves in development of, as well as protection against, ischemic injury is of current interest since it may involve recruitment of intrinsic cardiac ganglia...
June 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28706468/retinal-metabolic-events-in-preconditioning-light-stress-as-revealed-by-wide-spectrum-targeted-metabolomics
#15
Juan Manuel Chao de la Barca, Nuan-Ting Huang, Haihan Jiao, Lydie Tessier, Cédric Gadras, Gilles Simard, Riccardo Natoli, Guillaume Tcherkez, Pascal Reynier, Krisztina Valter
INTRODUCTION: Light is the primary stimulus for vision, but may also cause damage to the retina. Pre-exposing the retina to sub-lethal amount of light (or preconditioning) improves chances for retinal cells to survive acute damaging light stress. OBJECTIVES: This study aims at exploring the changes in retinal metabolome after mild light stress and identifying mechanisms that may be involved in preconditioning. METHODS: Retinas from 12 rats exposed to mild light stress (1000 lux × for 12 h) and 12 controls were collected one and seven days after light stress (LS)...
2017: Metabolomics: Official Journal of the Metabolomic Society
https://www.readbyqxmd.com/read/28692063/inflammation-dependent-cerebrospinal-fluid-hypersecretion-by-the-choroid-plexus-epithelium-in-posthemorrhagic-hydrocephalus
#16
Jason K Karimy, Jinwei Zhang, David B Kurland, Brianna Carusillo Theriault, Daniel Duran, Jesse A Stokum, Charuta Gavankar Furey, Xu Zhou, M Shahid Mansuri, Julio Montejo, Alberto Vera, Michael L DiLuna, Eric Delpire, Seth L Alper, Murat Gunel, Volodymyr Gerzanich, Ruslan Medzhitov, J Marc Simard, Kristopher T Kahle
The choroid plexus epithelium (CPE) secretes higher volumes of fluid (cerebrospinal fluid, CSF) than any other epithelium and simultaneously functions as the blood-CSF barrier to gate immune cell entry into the central nervous system. Posthemorrhagic hydrocephalus (PHH), an expansion of the cerebral ventricles due to CSF accumulation following intraventricular hemorrhage (IVH), is a common disease usually treated by suboptimal CSF shunting techniques. PHH is classically attributed to primary impairments in CSF reabsorption, but little experimental evidence supports this concept...
August 2017: Nature Medicine
https://www.readbyqxmd.com/read/28687561/impact-of-vascular-hemodynamics-on-aortic-stenosis-evaluation-new-insights-into-the-pathophysiology-of-normal-flow-small-aortic-valve-area-low-gradient-pattern
#17
Nancy Côté, Louis Simard, Anne-Sophie Zenses, Lionel Tastet, Mylène Shen, Marine Clisson, Marie-Annick Clavel
BACKGROUND: About 50% of normal-flow/low-gradient patients (ie, low mean gradient [MG] or peak aortic jet velocity and small aortic valve area) have severe aortic valve calcification as measured by computed tomography. However, they are considered to have moderate aortic stenosis (AS) in current American College of Cardiology/American Heart Association guidelines. The objective was thus to evaluate the effect of hypertension and reduced arterial compliance (rAC) on MG and Vpeak measurements...
July 7, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28679302/an-evidence-based-approach-to-the-creation-of-normative-data-base-rates-of-impaired-scores-within-a-brief-neuropsychological-battery-argue-for-age-corrections-but-against-corrections-for-medical-conditions
#18
Megan E O'Connell, Holly Tuokko, Stacey Voll, Martine Simard, Lauren E Griffith, Vanessa Taler, Christina Wolfson, Susan Kirkland, Parminder Raina
OBJECTIVE: We detail a new approach to the creation of normative data for neuropsychological tests. The traditional approach to normative data creation is to make demographic adjustments based on observations of correlations between single neuropsychological tests and selected demographic variables. We argue, however, that this does not describe the implications for clinical practice, such as increased likelihood of misclassification of cognitive impairment, nor does it elucidate the impact on decision-making with a neuropsychological battery...
July 5, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28676071/effectiveness-of-an-intervention-to-improve-supportive-care-for-family-caregivers-of-patients-with-lung-cancer-study-protocol-for-a-randomized-controlled-trial
#19
Michèle Aubin, Lucie Vézina, René Verreault, Sébastien Simard, Jean-François Desbiens, Lise Tremblay, Serge Dumont, Lise Fillion, Maman Joyce Dogba, Pierre Gagnon
BACKGROUND: Family caregivers (FC) often experience higher distress levels than their relative with cancer. Many cancer centers have implemented distress screening programs, but most of them concentrate their efforts on patients, with little attention to their FC. To fill this gap, a pragmatic intervention has been designed to improve supportive care for FC of patients with lung cancer. This article describes the study protocol of a single-center randomized controlled trial to assess its effectiveness...
July 4, 2017: Trials
https://www.readbyqxmd.com/read/28675348/navien-catheter-experience-in-neuroendovascular-interventions
#20
Gaurav Jindal, Luciano Giacon, Moronke Iyoha, Timothy Miller, Francois Aldrich, Marc Simard, Ravishankar Shivashankar, Dheeraj Gandhi
Purpose Advancements in catheter technology have allowed for greater flexibility and trackability. We report 265 consecutive, single-center neurointerventional cases using the Navien guide catheter. Materials and methods Retrospective analysis was performed of consecutive intracranial endovascular procedures utilizing the Navien catheter. Data collected included procedure type, catheters, guide catheter position, cervical access artery tortuosity grade and complications. Results The 5 French catheter was used in 130 cases...
January 1, 2017: Interventional Neuroradiology
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