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https://www.readbyqxmd.com/read/27922036/incontinence-treating-women-with-refractory-urge-urinary-incontinence
#1
Roger Dmochowski
No abstract text is available yet for this article.
December 6, 2016: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27920507/men-s-preferences-for-the-treatment-of-lower-urinary-tract-symptoms-associated-with-benign-prostatic-hyperplasia-a-discrete-choice-experiment
#2
Colette Mankowski, Divine Ikenwilo, Sebastian Heidenreich, Mandy Ryan, Jameel Nazir, Cathy Newman, Verity Watson
OBJECTIVE: To explore and quantify men's preferences and willingness to pay (WTP) for attributes of medications for lower urinary tract symptoms associated with benign prostatic hyperplasia using a discrete choice experiment. SUBJECTS AND METHODS: Men in the UK aged ≥45 years with moderate-to-severe lower urinary tract symptoms/benign prostatic hyperplasia (based on self-reported International Prostate Symptom Score ≥8) were recruited. An online discrete choice experiment survey was administered...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27918838/quality-of-governance-and-effectiveness-of-protected-areas-crucial-concepts-for-conservation-planning
#3
Johanna Eklund, Mar Cabeza
Protected areas (PAs) are a key tool for biodiversity conservation and play a central role in the Convention on Biological Diversity. Recently, the effectiveness of PAs has been questioned, and assessing how effective they are in enabling the future persistence of biodiversity is not trivial. Here, we focus on terrestrial PAs and clarify the terminology related to PA effectiveness, distinguishing between management and ecological aspects. We suggest that the quality of governance affects both aspects of effectiveness but recognize a lack of synthetic understanding of the topic...
December 5, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27914047/deterministic-search-methods-for-computational-protein-design
#4
Seydou Traoré, David Allouche, Isabelle André, Thomas Schiex, Sophie Barbe
One main challenge in Computational Protein Design (CPD) lies in the exploration of the amino-acid sequence space, while considering, to some extent, side chain flexibility. The exorbitant size of the search space urges for the development of efficient exact deterministic search methods enabling identification of low-energy sequence-conformation models, corresponding either to the global minimum energy conformation (GMEC) or an ensemble of guaranteed near-optimal solutions. In contrast to stochastic local search methods that are not guaranteed to find the GMEC, exact deterministic approaches always identify the GMEC and prove its optimality in finite but exponential worst-case time...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27913051/erg-expression-in-multiple-myeloma-a-potential-diagnostic-pitfall
#5
Juliana Knief, Katharina Reddemann, Jan Gliemroth, Swantje Brede, Tobias Bartscht, Christoph Thorns
INTRODUCTION: ERG expression has been described as a frequent event in prostate cancer indicating poor prognosis and promoting oncogenesis. It has also been demonstrated in Ewing's sarcoma, acute myeloid leukemia and acute T-lymphoblastic leukemia but could not be found in other epithelial tumors, Hodgkin's or Non-Hodgkin's lymphoma. We aimed to analyze ERG expression in multiple myeloma, following an index case of a patient with metastases of unknown origin in the spine strongly expressing ERG, which were thought to be of prostatic origin but turned out to be plasmacytic lesions...
November 3, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/27904215/morphometry-of-distal-end-radius-in-the-indian-population-a-radiological-study
#6
Pankaj Kumar Mishra, Manoj Nagar, Suresh Chandra Gaur, Anuj Gupta
INTRODUCTION: The morphometry of distal end radius (DER) comprises the four necessary parameters: radial inclination, palmer tilt, radial height, and ulnar variance. The unblemished intellect about the morphometry is urged for the management of fracture of DER. The goal of our study was to determine the values of morphometric parameters of the DER from the adult Indian. MATERIALS AND METHODS: It was a single hospital- based observational cross-sectional, prospective study...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27902502/zika-virus-and-patient-blood-management
#7
Lawrence T Goodnough, Marisa B Marques
Sporadic Zika virus infections had only occurred in Africa and Asia until an outbreak in Micronesia (Oceania) in 2007. In 2013 to 2014, several outer Pacific Islands reported local outbreaks. Soon thereafter, the virus was likely introduced in Brazil from competing athletes from French Polynesia and other countries that participated in a competition there. Transmission is thought to have occurred through mosquito bites and spread to the immunologically naive population. Being also a flavivirus, the Zika virus is transmitted by the Aedes mosquito that is endemic in South and Central America that is also the vector of West Nile virus, dengue, and chikungunya...
November 29, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27902127/child-abuse-inquiry-urges-nurses-to-help-survivors-tell-their-stories
#8
Flavia Munn
Nurses, midwives and health visitors encounter victims of historical and current abuse in a variety of healthcare settings and specialties. The Independent Inquiry into Child Sexual Abuse, which is looking at the extent to which institutions and organisations in England and Wales have failed to protect children from sexual abuse, wants nurses' help in supporting patients who may have information to contribute.
November 30, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27901515/neurocognitive-and-clinical-correlates-of-gambling-behavior-based-on-mode-of-gambling
#9
Eric W Leppink, Austin W Blum, Samuel Chamberlain, Jon E Grant
BACKGROUND: Gambling opportunities have expanded greatly in recent years, with ever-increasing availability via the internet as well as land-based options (eg, casinos). Although some research suggests that internet gamblers have higher rates of disordered gambling than land-based only gamblers, the clinical and cognitive importance of these findings is unknown. METHODS: We recruited 542 young adults (age 18 to 29) and compared land- based only (n = 385 [70.8%]) and mixed internet/land-based gamblers (LBGs) (n = 157 [28...
November 2016: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/27898453/resolution-of-rectal-prolapse-by-vaginal-reconstruction
#10
Hemikaa Devakumar, Neeraja Chandrasekaran, Alexandriah Alas, Laura Martin, G Willy Davila, Eric Hurtado
BACKGROUND: Rectal prolapse is a disorder of the pelvic floor in which the layers of the rectal mucosa protrude outward through the anus. Surgical repair is the mainstay of treatment. Options include intra-abdominal procedures such as rectopexy and perineal procedures such as the Delorme and Altemeier perineal rectosigmoidectomy. Rectal and vaginal prolapse can often coexist. However, to our knowledge, there are no reported cases of rectal prolapse resolved by the repair of a compressive enterocele abutting the anterior rectal wall through a vaginal approach alone...
November 28, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27896797/a-telephone-based-intervention-to-promote-physical-activity-during-smoking-cessation-a-randomized-controlled-proof-of-concept-study
#11
Uma S Nair, Freda Patterson, Daniel Rodriguez, Bradley N Collins
Smoking and physical inactivity contribute to disproportionate disease burden among underserved adults. Telephone-based interventions (quitlines) are becoming the standard care for addressing smoking. There is increasing interest to determine whether quitlines can be utilized to administer interventions for other unhealthy behaviors. This study aims to examine the proof-of-concept and potential efficacy of a telephone-based behavioral counseling intervention to boost daily low-to-moderate physical activity among low-income, physically inactive smokers...
November 28, 2016: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/27895940/real-time-reporting-of-small-operational-failures-in-nursing-care
#12
Kathleen R Stevens, Robert L Ferrer
Addressing microsystem problems from the frontline holds promise for quality enhancement. Frontline providers are urged to apply quality improvement; yet no systematic approach to problem detection has been tested. This study investigated a self-report approach to detecting operational failures encountered during patient care. Methods. Data were collected from 5 medical-surgical units over 4 weeks. Unit staff documented operational failures on a small distinctive Pocket Card. Frequency distributions for the operational failures in each category were calculated for each hospital overall and disaggregated by shift...
2016: Nursing Research and Practice
https://www.readbyqxmd.com/read/27895908/diathermy-awareness-among-surgeons-an-analysis-in-ireland
#13
P M McQuail, B S McCartney, J F Baker, P Kenny
INTRODUCTION: Diathermy is an integral part of many modern surgical procedures. While diathermy is generally accepted as 'safe', electrosurgery-induced injuries are among the more common causes for malpractice litigation. The purpose of this study was to evaluate the awareness among surgeons of the principles, risks, precautions and appropriate use of diathermy. METHODS: All surgeons employed from Senior House Officer (SHO) to Consultant grade in two teaching hospitals were surveyed...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27894160/cue-induced-nicotine-seeking-behavior-after-withdrawal-with-or-without-extinction-in-rats
#14
Athina Markou, Jie Li, Kearny Tse, Xia Li
Exposure to smoking-associated environmental cues during smoke cessation elicits self-reported urge/craving to smoke, which precipitates relapse even after prolonged abstinence. Incubation of cue-induced cigarettes craving during abstinence has been observed in human smokers recently. The present studies assessed cue-induced nicotine-seeking behavior under different withdrawal conditions in rats with a history of nicotine self-administration. We found that non-reinforced operant responding during cue-induced nicotine seeking after different periods of withdrawal from nicotine exhibited an inverted U-shaped curve, with higher levels of responding after 7-21 days of withdrawal than those after 1-day withdrawal...
November 28, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27889999/comprehensive-assessment-of-compliance-with-antimuscarinic-drug-treatment-in-the-case-of-urge-urinary-incontinence-of-older-patients
#15
Kirill Vladimirovich Kosilov, Sergey Alexandrovich Loparev, Irina Gennadyevna Kuzina, Olga Viktorovna Shakirova, Natalya Sergeevna Zhuravskaya, Alexandra Lobodenko
AIM: study of heterogeneous factors affecting the stability of patients older than 60 years in the UI treatment with Antimuscarinics. BACKGROUND: The prevalence of urge incontinence (UI) in older persons reaches 29.3%. The symptoms of urinary incontinence in older people reduce the health related life quality. MATERIALS AND METHODS: In 1257 patients over 60 years (857 (68.2%) women - average age 67.8, 400 (31.8%) men - 71.4), who received AM for one year, demographic, socio-economic and health parameters were studied...
November 24, 2016: Current Aging Science
https://www.readbyqxmd.com/read/27889687/role-of-inflammation-in-obesity-related-breast-cancer
#16
REVIEW
Elisa Crespi, Giulia Bottai, Libero Santarpia
Chronic inflammation associated with obesity is now recognized to be an important condition in promoting carcinogenesis and progression in breast cancer patients, mostly in postmenopausal women with tumors expressing estrogen and progesterone receptors. In obese patients, altered levels of several inflammatory mediators regulating aromatase and estrogen expression are one of the mechanisms responsible of increase breast cancer risk. Growing attention has also been paid to the local adipose inflammation and the role played by macrophages as determinants of breast cancer risk recurrence and prognosis...
November 24, 2016: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/27884470/the-first-exposure-assessment-of-legacy-and-unrestricted-brominated-flame-retardants-in-predatory-birds-of-pakistan
#17
Naeem Akhtar Abbasi, Igor Eulaers, Veerle Leontina Bernard Jaspers, Muhammad Jamshed Iqbal Chaudhry, Adrien Frantz, Per Lennart Ambus, Adrian Covaci, Riffat Naseem Malik
The exposure to legacy polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDDs) and unrestricted 1,2-bis (2,4,6-tribromophenoxy) ethane (BTBPE), bis (2-ethylhexyl)-2,3,4,5-tetrabromophthalate (BEH-TEBP) and 2-ethylhexyl-2,3,4,5-tetrabromo-benzoate (EH-TBB) was examined in tail feathers of 76 birds belonging to ten predatory species inhabiting Pakistan. In addition, different feather types of six individuals of Black kite (Milvus migrans) were compared for their brominated flame retardant (BFR) levels...
January 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27884104/phylogeography-reveals-an-ancient-cryptic-radiation-in-east-asian-tree-frogs-hyla-japonica-group-and-complex-relationships-between-continental-and-island-lineages
#18
Christophe Dufresnes, Spartak N Litvinchuk, Amaël Borzée, Yikweon Jang, Jia-Tang Li, Ikuo Miura, Nicolas Perrin, Matthias Stöck
BACKGROUND: In contrast to the Western Palearctic and Nearctic biogeographic regions, the phylogeography of Eastern-Palearctic terrestrial vertebrates has received relatively little attention. In East Asia, tectonic events, along with Pleistocene climatic conditions, likely affected species distribution and diversity, especially through their impact on sea levels and the consequent opening and closing of land-bridges between Eurasia and the Japanese Archipelago. To better understand these effects, we sequenced mitochondrial and nuclear markers to determine phylogeographic patterns in East-Asian tree frogs, with a particular focus on the widespread H...
November 23, 2016: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/27881876/the-efficacy-of-high-throughput-sequencing-and-target-enrichment-on-charred-archaeobotanical-remains
#19
H M Nistelberger, O Smith, N Wales, B Star, S Boessenkool
The majority of archaeological plant material is preserved in a charred state. Obtaining reliable ancient DNA data from these remains has presented challenges due to high rates of nucleotide damage, short DNA fragment lengths, low endogenous DNA content and the potential for modern contamination. It has been suggested that high-throughput sequencing (HTS) technologies coupled with DNA enrichment techniques may overcome some of these limitations. Here we report the findings of HTS and target enrichment on four important archaeological crops (barley, grape, maize and rice) performed in three different laboratories, presenting the largest HTS assessment of charred archaeobotanical specimens to date...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27877063/copd-patients-medical-care-and-support-in-greece-during-financial-crisis
#20
George Mitonas, Alexia Juvana, Zoe Daniil, Chryssa Hatzoglou, Konstantinos Gourgoulianis
BACKGROUND: The need to follow a multidisciplinary strategy in chronic obstructive pulmonary disease (COPD) management and rehabilitation in community settings in Greece raises significant questions, given the severe austerity measures being imposed at present. The aim of this study was to investigate the clinical profile of patients with COPD along with the care provided in rural community settings in Greece. METHODS: Two primary health care centers and 200 newly diagnosed patients over a 12-month period were involved in the study...
2016: International Journal of General Medicine
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