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Endocrine gynecology

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https://www.readbyqxmd.com/read/28285615/consensus-on-the-integrated-traditional-chinese-and-western-medicine-criteria-of-diagnostic-classification-in-polycystic-ovary-syndrome-draft
#1
Jin Yu, Chao-Qin Yu, Qi Cao, Li Wang, Wen-Jun Wang, Li-Rong Zhou, Jing Li, Qiao-Hong Qian
Polycystic ovary syndrome (PCOS) is the most common endocrine and metabolic disorder of women, with complex pathogenesis and heterogeneous manifestations. Professor Jin Yu recently wrote an article entitled "Proposal of Diagnosis and Diagnostic Classification of PCOS in Integrated Traditional Chinese and Western Medicine."From this, the Obstetrics and Gynecology branches of the Chinese Association of Integrative Medicine and the China Association of Chinese Medicine collaborated with the Gynecology branch of the Chinese Association for Research and Advancement of Chinese Medicine to draft a report on the consensus of criteria for the diagnosis and classification of PCOS in integrated traditional Chinese and Western medicine...
March 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28285614/effectiveness-of-co-treatment-with-traditional-chinese-medicine-and-letrozole-for-polycystic-ovary-syndrome-a-meta-analysis
#2
Qian-Wen Ma, Yong Tan
BACKGROUND: Polycystic ovary syndrome (PCOS) is an endocrine disease that affects gynecological health. Treatment of PCOS remains a big challenge for clinicians. OBJECTIVE: This meta-analysis was developed to compare the efficacy of co-treatment with traditional Chinese medicine (TCM) and letrozole against letrozole monotherapy in the treatment of PCOS. SEARCH STRATEGY: Randomized controlled trials (RCTs) were electronically retrieved from PubMed, Cochrane Library, China Biomedical Literature Database, China National Knowledge Infrastructure and Wanfang Data; related papers that were not available electronically were manually checked...
March 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28283302/perfluoroalkyl-substances-and-endometriosis-related-infertility-in-chinese-women
#3
Bin Wang, Rongrong Zhang, Fan Jin, Hangying Lou, Yuchan Mao, Wenting Zhu, Wei Zhou, Ping Zhang, Jun Zhang
Endometriosis is one of the main causes for female infertility. Previous studies suggested that perfluoroalkyl substances (PFASs), a group of ubiquitous environmental chemicals with properties of endocrine disruption and reproductive toxicity, were risk factors for endometriosis but there lacks direct evidence on the possible role of PFASs in endometriosis-related infertility. To fill this gap, we examined the association between PFASs and endometriosis-related infertility among Chinese reproductive-age women in a case-control study, which comprised 157 surgically confirmed endometriosis cases and 178 controls seeking infertility treatment because of male reproductive dysfunction in 2014 and 2015...
March 7, 2017: Environment International
https://www.readbyqxmd.com/read/28274349/sex-hormones-and-acne
#4
Qiang Ju, Tao Tao, Tingting Hu, Ayşe Serap Karadağ, Safaa Al-Khuzaei, WenChieh Chen
The skin is an endocrine organ with the expression of metabolizing enzymes and hormone receptors for diverse hormones. The sebaceous gland is the main site of hormone biosynthesis, especially for androgens, and acne is the classical androgen-mediated dermatosis. In sebocytes, conversion of 17-hydroxyprogesterone directly to dihydrotestosterone bypassing testosterone has been demonstrated, while type II 17β-hydroxysteroid dehydrogenase can inactivate the action of testosterone and dihydrotestosterone. The androgen receptor-dependent genomic effect of dihydrotestosterone on sebocytes is confirmed...
March 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28099715/assessment-of-the-body-composition-of-patients-with-polycystic-ovary-syndrome-using-dual-energy-x-ray-absorptiometry
#5
Carolina F Macruz, Sônia M R R Lima, João E N Salles, Gustavo M D da Silva, Nilza M Scalissi
OBJECTIVE: To compare the body composition among patients with polycystic ovary syndrome (PCOS) and patients without PCOS. METHODS: A cross-sectional study enrolled patients aged 12-39 years, with body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) at least 18.5 but below 25, who attended the Endocrine Gynecology Clinic of Santa Casa de Sao Paulo School of Medical Sciences, Brazil, between January 1, 2014, and July 31, 2015...
March 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28074550/treatment-strategy-for-urinary-frequency-in-women
#6
Ching-Hung Hsieh, Tsung-Hsien Su
The purpose of this paper is to discuss the differential diagnosis of the underlying etiologies of urinary frequency and the treatment strategies for urinary frequency in women. Urinary frequency is a symptom, a sign, and a condition of uncertainty and of multifactorial cause. Common causes of urinary frequency include psychosocial, medical, sexual, urological, gynecologic, endocrine, and pharmacological in origin. Hence, treatment of symptoms and possible cures need a high-level plan or strategy to overcome the multifactorial etiology...
January 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27741188/disorders-of-sexual-development-in-adult-women
#7
Veronica Gomez-Lobo, Anne-Marie Amies Oelschlager
Disorders (differences) of sexual development encompass a variety of conditions with atypical development of chromosomal, gonadal, or anatomic sex. Three of the most common differences of sex development conditions include congenital adrenal hyperplasia, complete androgen insensitivity, and Turner syndrome. Obstetrician-gynecologists who care for affected individuals in their practice must be familiar with the genetic, endocrine, and anatomic considerations of the most common conditions to provide optimal care...
November 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27696906/the-role-of-fulvestrant-in-endometrial-cancer
#8
Stefano Bogliolo, Chiara Cassani, Mattia Dominoni, Anna Orlandini, Simone Ferrero, Anna Daniela Iacobone, Franco Viazzo, Pier Luigi Venturini, Arsenio Spinillo, Barbara Gardella
Endometrial cancer is the most common malignancy of the female genital tract in industrialized countries. The traditional treatment of endometrial cancer is based on a surgical approach. In recent years, systemic endocrine therapy has demonstrated good efficacy in recurrent or metastatic setting, delaying progression, ameliorating quality of life and palliating symptoms. Areas covered: Phase I and II studies on selective estrogen receptor down-regulators used for the treatment of endometrial cancer treatment have been reviewed...
October 4, 2016: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/27651661/endocrine-and-metabolic-profile-of-different-phenotypes-of-polycystic-ovarian-syndrome
#9
Saxena Pikee, Singh Shivani, Bhattacharjee Jayshree
BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common endocrinopathy associated with wide heterogeneity and serious clinical implications. Prevalence and characteristics of different phenotypes are not well defined. Therefore, this study was planned to determine the prevalence of four phenotypes of PCOS and to evaluate their endocrine and metabolic parameters including insulin resistance and metabolic syndrome with respect to controls. METHODS: This observational, case-control study was conducted in the gynecology outpatient department of a tertiary care center where 161 PCOS and 50 non-PCOS women were recruited and investigated...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27617151/syndrome-associated-tumors-by-organ-system
#10
REVIEW
Raul S Gonzalez, Nicole D Riddle
Certain tumors suggest the possibility of a patient harboring a genetic syndrome, particularly in children. Syndrome-associated tumors of the gastrointestinal tract, genitourinary tract, gynecologic tract, heart, lungs, brain, eye, endocrine organs, and hematopoietic system will be briefly discussed.
June 2016: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/27563566/management-dilemma-of-thyroid-nodules-in-patients-with-malignant-struma-ovarii
#11
Sarah J Sternlieb, Celine Satija, David T Pointer, Byron E Crawford, Lacey Sullivan, Emad Kandil
Struma ovarii is a rare type of ovarian teratoma comprised of at least 50% thyroid tissue. While most are benign, 70% of malignant cases are diagnosed as papillary carcinoma. Management of patients with thyroid nodules following gynecologic surgery remains controversial and variable. Historically, the treatment of choice has been surgical removal to rule out ovarian carcinoma. Thyroid follow-up and further treatment options are guided by tumor characteristics. The patient in this case presented to the endocrine surgeon with multiple thyroid nodules, dysphagia and a history of struma ovarii that was surgically treated at an outside hospital...
August 2016: Gland Surgery
https://www.readbyqxmd.com/read/27553264/endocrine-disrupting-chemicals-and-uterine-fibroids
#12
REVIEW
Tiffany A Katz, Qiwei Yang, Lindsey S Treviño, Cheryl Lyn Walker, Ayman Al-Hendy
Uterine fibroids are the most frequent gynecologic tumor, affecting 70% to 80% of women over their lifetime. Although these tumors are benign, they can cause significant morbidity and may require invasive treatments such as myomectomy and hysterectomy. Many risk factors for these tumors have been identified, including environmental exposures to endocrine-disrupting chemicals (EDCs) such as genistein and diethylstilbestrol. Uterine development may be a particularly sensitive window to environmental exposures, as some perinatal EDC exposures have been shown to increase tumorigenesis in both rodent models and human epidemiologic studies...
September 15, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27516680/principles-of-nutrition-in-patients-with-polycystic-ovary-syndrome-in-iranian-traditional-medicine-and-comparison-with-modern-medicine
#13
Mojgan Tansaz, Maryam Bahmani
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age with metabolic and gynecological complications. Despite the high prevalence of this disease, many challenges remain regarding its diagnosis and treatment. According to many studies, lifestyle modification especially diet is the first line of the treatment in PCOS patients. The aim of this article was to study the principles of nutrition for PCOS patients in Iranian traditional medicine (ITM) in comparison with modern medicine...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27490770/endocrine-disruptors-a-potential-risk-factor-for-gestational-diabetes-mellitus
#14
Shelley Ehrlich, Donna Lambers, Andrea Baccarelli, Jane Khoury, Maurizio Macaluso, Shuk-Mei Ho
Gestational diabetes mellitus (GDM) has increased dramatically in the past 20 years together with the obesity epidemic. Mirroring the increase in incidence of GDM is increasing use of endocrine disrupting chemicals (EDCs). EDCs are structurally similar to endogenous hormones and interfere with synthesis, secretion, activity, or elimination of natural hormones, resulting in adverse health effects, including diabetes, obesity, developmental disorders, etc. Although the association between bisphenol A (BPA), a well-studied EDC, and type 2 diabetes has been repeatedly investigated in epidemiological and animal studies, there is a dearth of studies examining EDCs and GDM...
August 4, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27424048/endocrine-disrupting-chemicals-and-endometriosis
#15
REVIEW
Melissa M Smarr, Kurunthachalam Kannan, Germaine M Buck Louis
Endometriosis is an estrogen dependent gynecologic disease with lasting implications for many women's fertility, somatic health, and overall quality of life. Growing evidence suggests that endocrine disrupting chemicals (EDCs) may be etiologically involved in the development and severity of disease. We weigh the available human evidence focusing on EDCs and endometriosis, restricting to research that has individually quantified chemical concentrations for women, included a comparison group of unaffected women, and used multivariable analytic techniques...
September 15, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27419327/diagnosis-and-treatment-of-polycystic-ovary-syndrome
#16
Tracy Williams, Rami Mortada, Samuel Porter
Polycystic ovary syndrome is the most common endocrinopathy among reproductive-aged women in the United States, affecting approximately 7% of female patients. Although the pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. Metabolic syndrome is twice as common in patients with polycystic ovary syndrome compared with the general population, and patients with polycystic ovary syndrome are four times more likely than the general population to develop type 2 diabetes mellitus...
July 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27410167/quality-of-life-and-burnout-rates-across-surgical-specialties-a-systematic-review
#17
Marisa Pulcrano, Stephen R T Evans, Michael Sosin
Importance: Establishing strategies to minimize the burden of burnout and poor quality of life (QOL) on surgeons relies on a thorough understanding of QOL and burnout among the various surgical specialties. Objectives: To systematically review the literature across multiple surgical specialties and provide a comprehensive understanding of QOL and burnout among all surgeons, to delineate variation in rates of burnout and poor QOL, and to elucidate factors that are commonly implicated in these outcomes...
July 13, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27321097/flexible-gnrh-antagonist-protocol-vs-long-gnrh-agonist-protocol-in-patients-with-polycystic-ovary-syndrome-treated-for-ivf-comparison-of-clinical-outcome-and-embryo-quality
#18
Milan Trenkić, Jasmina Popović, Vesna Kopitović, Artur Bjelica, Radomir Živadinović, Sonja Pop-Trajković
OBJECTIVES: Polycystic ovary syndrome (PCOS) is a common endocrine disorder, primarily affecting women of the reproductive age. The aim of the study was to assess the clinical efficacy and embryo quality in flexible gonadotropin-releasing hormone (GnRH) antagonist protocol in comparison to the long GnRH agonist protocol in PCOS women undergoing in vitro fertilization (IVF). MATERIAL AND METHODS: This prospective, randomized study was conducted at the Department of Gynecology and Obstetrics, Clinical Center Niš, Serbia, between 2013 and 2014...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27300031/fertility-in-women-of-late-reproductive-age-the-role-of-serum-anti-m%C3%A3-llerian-hormone-amh-levels-in-its-assessment
#19
REVIEW
B Meczekalski, A Czyzyk, M Kunicki, A Podfigurna-Stopa, L Plociennik, G Jakiel, M Maciejewska-Jeske, K Lukaszuk
INTRODUCTION: Fertility is referred to the capability for having offspring and can be evaluated by fertility rate. Women's fertility is strictly dependent on individual's age. The fertility peak occurs in the early 20s, and it starts to decline in the third and fourth decades of life (falling sharply after age 35). AIM: The aim of this work is to review the available data concerning fertility in women of late reproductive age, especially the role of serum anti-Müllerian hormone (AMH) levels...
November 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27275273/the-health-status-of-the-reproductive-system-in-women-living-in-the-aral-sea-region
#20
Yasminur G Turdybekova, Raushan S Dosmagambetova, Symbat U Zhanabayeva, Gena V Bublik, Alik B Kubayev, Zhanbolat G Ibraibekov, Irina L Kopobayeva, Berikbay Zh Kultanov
In order to assess women's reproductive health in the Kyzylorda region (the Aral Sea) of Kazakhstan, 1406 women were involved in an integrated clinical-functional and laboratory examination, given regional and environmental ecological factors. The high level of endocrine gynecological pathology is indicated in the examined women. In both examined zones, there is a late menarche over 16 years old, which is 39%. It is indicated a trend towards younger age of menopause onset. Inflammatory diseases of the female genital organs affect a third of the examined women...
September 15, 2015: Open Access Macedonian Journal of Medical Sciences
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