keyword
https://read.qxmd.com/read/38546511/a-case-series-of-the-royal-perth-hospital-cannula-first-approach-in-the-can-t-intubate-can-t-oxygenate-scenario
#1
JOURNAL ARTICLE
Andrew Mb Heard, David A Lacquiere, Helen L Gordon, Scott G Douglas, Hans J Avis
At the Royal Perth Hospital, we have been developing and teaching a can't intubate, can't oxygenate (CICO) rescue algorithm for over 19 years, based on live animal simulation. The algorithm involves a 'cannula-first' approach, with jet oxygenation and progression to scalpel techniques if required in a stepwise fashion. There is little reported experience of this approach to the CICO scenario in humans. We present eight cases in which a cannula-first Royal Perth Hospital approach was successfully implemented during an airway crisis...
March 28, 2024: Anaesthesia and Intensive Care
https://read.qxmd.com/read/38541052/artificial-intelligence-supported-ultrasonography-in-anesthesiology-evaluation-of-a-patient-in-the-operating-theatre
#2
REVIEW
Sławomir Mika, Wojciech Gola, Monika Gil-Mika, Mateusz Wilk, Hanna Misiołek
Artificial intelligence has now changed regional anesthesia, facilitating, therefore, the application of the regional block under the USG guidance. Innovative technological solutions make it possible to highlight specific anatomical structures in the USG image in real time, as needed for regional block. This contribution presents such technological solutions as U-Net architecture, BPSegData and Nerveblox and the basis for independent assisting systems in the use of regional blocks, e.g., ScanNav Anatomy PNB or the training system NeedleTrainer...
March 15, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38539078/prevention-of-postoperative-nausea-and-vomiting-after-orthognathic-surgery-a-scoping-review
#3
JOURNAL ARTICLE
Peng-Fei Gao, Le Zhao, Shi-Yue Li, Yue Li, Ming-Kai Chen, Jing Fu, Yang Ji
INTRODUCTION: Postoperative nausea and vomiting (PONV) is one of the most common adverse events following orthognathic surgery. It's a distressing feeling for patients and continues to be the cause of postoperative complications such as bleeding, delayed healing, and wound infection. This scoping review aims to identify effective PONV prophylaxis strategies during orthognathic surgery that have emerged in the past 15 years. METHODS: We searched Pubmed, Cochrane Controlled Register of Trials, and Embase from 2008 to May 2023...
March 28, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38537520/the-movement-of-syringes-and-medication-during-anesthesiology-delivery-an-observational-study-in-laparoscopic-surgeries
#4
JOURNAL ARTICLE
David M Neyens, Rong Yin, James H Abernathy, Catherine Tobin, Candace Jaruzel, Ken Catchpole
The movements of syringes and medications during an anesthetic case have yet to be systematically documented. We examine how syringes and medication move through the anesthesia work area during a case. We conducted a video-based observational study of 14 laparoscopic surgeries. We defined 'syringe events' as when syringe was picked up and moved. Medications were administered to the patient in only 48 (23.6%) of the 203 medication or syringe events. On average, 14.5 syringe movements occurred in each case. We estimate approximately 4...
March 26, 2024: Applied Ergonomics
https://read.qxmd.com/read/38537025/effects-of-an-early-intensive-blood-pressure-lowering-strategy-using-remifentanil-and-dexmedetomidine-in-patients-with-spontaneous-intracerebral-hemorrhage-a-multicenter-prospective-superiority-randomized-controlled-trial
#5
JOURNAL ARTICLE
Rui Dong, Fen Li, Bin Li, Qiming Chen, Xianjian Huang, Jiehua Zhang, Qibing Huang, Zeli Zhang, Yunxing Cao, Mingbiao Yang, Jianwei Li, Zhanfu Li, Cuiyu Li, Guohua Liu, Shu Zhong, Guang Feng, Ming Zhang, Yumei Xiao, Kangyue Lin, Yunlong Shen, Huanzhang Shao, Yuan Shi, Xiangyou Yu, Xiaopeng Li, Lan Yao, Xinyu Du, Ying Xu, Pei Kang, Guoyi Gao, Bin Ouyang, Wenjin Chen, Zhenhua Zeng, Pingyan Chen, Chunbo Chen, Hong Yang
BACKGROUND: Although it has been established that elevated blood pressure and its variability worsen outcomes in spontaneous intracerebral hemorrhage, antihypertensives use during the acute phase still lacks robust evidence. A blood pressure-lowering regimen using remifentanil and dexmedetomidine might be a reasonable therapeutic option given their analgesic and anti-sympathetic effects. The objective of this superiority trial was to validate the efficacy and safety of this blood pressure-lowering strategy that uses remifentanil and dexmedetomidine in patients with acute intracerebral hemorrhage...
March 27, 2024: Anesthesiology
https://read.qxmd.com/read/38536739/a-scoping-review-of-the-mechanisms-underlying-developmental-anesthetic-neurotoxicity
#6
JOURNAL ARTICLE
Matthew Thomas Borzage, Bradley S Peterson
Although anesthesia makes painful or uncomfortable diagnostic and interventional health care procedures tolerable, it may also disrupt key cellular processes in neurons and glia, harm the developing brain, and thereby impair cognition and behavior in children. Many years of studies using in vitro, animal behavioral, retrospective database studies in humans, and several prospective clinical trials in humans have been invaluable in discerning the potential toxicity of anesthetics. The objective of this scoping review was to synthetize the evidence from preclinical studies for various mechanisms of toxicity across diverse experimental designs and relate their findings to those of recent clinical trials in real-world settings...
March 27, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38535971/research-progress-on-the-association-between-microrna-and-postoperative-cognitive-dysfunction
#7
JOURNAL ARTICLE
Yuanping Zhong, Yu Zhang, Zhaoqiong Zhu
Postoperative cognitive dysfunction (POCD) is a significant complication following surgery. The precise mechanisms underlying POCD remain elusive, although it is speculated that they involve central nervous system inflammation, oxidative stress and cellular apoptosis. MicroRNAs (miRNAs), a class of non-coding RNAs widely distributed in eukaryotes, have been implicated in the pathogenesis of neurodegenerative disorders and could potentially impact POCD. This review explores the association between miRNAs and POCD and provides an overview of the progress of current research on miRNAs in the pathogenesis, diagnosis, and treatment of POCD...
March 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38531618/high-sensitive-troponint-interleukin-8-and-interleukin-6-link-with-post-surgery-risk-in-infant-heart-surgery
#8
JOURNAL ARTICLE
Elin M Thorlacius, Juho Keski-Nisula, Maria Vistnes, Tiina Ojala, Mattias Molin, Mats Synnergren, Birgitta S Romlin, Sven-Erik Ricksten, Håkan Wåhlander, Albert Gyllencreutz Castellheim
BACKGROUND: This study focuses on biomarkers in infants after open heart surgery, and examines the association of high-sensitive troponin T (hs-cTnT), interleukin-6 (IL-6), and interleukin-8 (IL-8) with postoperative acute kidney injury (AKI), ventilatory support time and need of vasoactive drugs. METHODS: Secondary exploratory study from a double-blinded clinical randomized trial (Mile-1) on 70 infants undergoing open heart surgery with cardiopulmonary bypass (CPB)...
March 26, 2024: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/38528564/anesthesia-decision-analysis-using-a-cloud-based-big-data-platform
#9
REVIEW
Shuiting Zhang, Hui Li, Qiancheng Jing, Weiyun Shen, Wei Luo, Ruping Dai
Big data technologies have proliferated since the dawn of the cloud-computing era. Traditional data storage, extraction, transformation, and analysis technologies have thus become unsuitable for the large volume, diversity, high processing speed, and low value density of big data in medical strategies, which require the development of novel big data application technologies. In this regard, we investigated the most recent big data platform breakthroughs in anesthesiology and designed an anesthesia decision model based on a cloud system for storing and analyzing massive amounts of data from anesthetic records...
March 25, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38525206/single-dose-intravenous-paracetamol-versus-placebo-in-postorthognathic-surgery-pain-a-randomized-clinical-trial
#10
JOURNAL ARTICLE
Thunshuda Sumphaongern, Pornchai Jansisyanont
BACKGROUND: The postorthognathic surgery patients experienced moderate to severe pain and could be at risk for opioid-related side effects. The aim of this study was to evaluate the efficacy of a single dose of intravenous paracetamol to control postorthognathic surgery pain and reduce opioid consumption. METHODS: The patients were randomized into two groups. The study group received intravenous paracetamol and the control group received a placebo immediately postoperation...
2024: Anesthesiology Research and Practice
https://read.qxmd.com/read/38522946/prolonged-duration-of-action-of-suxamethonium-in-pregnant-and-postpartum-patients-a-registry-study
#11
JOURNAL ARTICLE
Helene Dalsten, Vera Crone, Jacob Steinmetz, Christine L Rosager, Lars S Rasmussen, Matias Vested
BACKGROUND: Suxamethonium is hydrolysed by butyrylcholinesterase (BChE) and a low BChE activity can result in a prolonged duration of action of suxamethonium. The BChE activity is reduced during pregnancy and postpartum period by up to 33%. However, it can also be reduced by mutations in the BChE gene. In this study, we assessed BChE activity and mutations in the BChE gene in pregnant and postpartum patients with prolonged duration of action of suxamethonium. It was hypothesised that at least 30% of patients with a low BChE activity did not have a mutation in the BChE gene...
March 24, 2024: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/38522144/effects-of-esketamine-on-postoperative-negative-emotions-and-early-cognitive-disorders-in-patients-undergoing-non-cardiac-thoracic-surgery-a-randomized-controlled-trial
#12
JOURNAL ARTICLE
Tianyuan Luo, Zhimin Deng, Qiyang Ren, Fangfang Mu, You Zhang, Haiying Wang
STUDY OBJECTIVE: To investigate whether a single dosage of esketamine injection in the anesthesia period could improve postoperative negative emotions and early cognitive function in patients undergoing non-cardiac thoracic surgery. DESIGN: A prospective single center double blinded randomized placebo-controlled trial. SETTING: Perioperative period; operating room, post anesthesia care unit and hospital ward. PATIENTS: 129 adult patients that underwent elective non-cardiac thoracic surgery under general anesthesia...
March 23, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38517762/metformin-use-in-type-2-diabetics-and-delirium-after-noncardiac-surgery-a-retrospective-cohort-analysis
#13
JOURNAL ARTICLE
Stephania Paredes, Ayoub Harb, Julian Rössler, Maede Zookaei Nikoo, Kurt Ruetzler, Alparslan Turan, Xuan Pu, Daniel I Sessler
INTRODUCTION: The cause of postoperative delirium is unknown, but it is thought to result at least in part from inflammation. Metformin, besides its hypoglycemic properties, demonstrates anti-inflammatory effects systemically and in the brain. We tested the primary hypothesis that chronic metformin use in adults with type 2 diabetes is associated with less delirium during the first 5 days after major noncardiac surgery. Secondary outcomes were a composite of serious complications (myocardial infarction, cardiac arrest, stage 2-3 acute kidney injury [AKI], and mortality) and time to discharge alive...
March 22, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38513644/-relevance-of-the-allen-test-before-catheterization-of-the-radial-artery
#14
JOURNAL ARTICLE
Lena Reese, Thomas Wurmb, Patrick Meybohm, Maximilian Kippnich
Arterial catheterization is considered to be standard procedure for patients undergoing general anesthesia. The most common puncture site is the radial artery (RA), which carries a risk of RA occlusion. Several pieces of literature still recommend the performance of the Allen test (AT) to assess the circulation of the palmar arch. However, the result of the AT differs largely depending on the examiner and the test is not able to predict ischemic events correctly. Thus it appears that the performance of an AT is not mandatory before arterial cannulation...
March 2024: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://read.qxmd.com/read/38510522/development-and-evaluation-of-an-in-house-lumbar-puncture-simulator-for-first-year-resident-lumbar-puncture-procedure-learning
#15
JOURNAL ARTICLE
David Muñoz-Leija, Fernando Díaz González-Colmenero, Diego A Ramiréz-Mendoza, Norma G López-Cabrera, Hilda A Llanes-Garza, Dionicio Palacios-Ríos, Adrián A Negreros-Osuna
INTRODUCTION: Lumbar puncture (LP) is a common invasive technique considered an essential learning milestone for anesthesiologists due to its application in spinal anesthesia. We aimed to develop an in-house LP simulator, test its effectiveness in learning the steps to perform an LP and analyze its impact on the first-year residents' self-confidence at our hospital. METHODS:  We used 3D printing and silicone casting to create an LP simulator based on a lumbar spine computed tomography (CT)...
March 2024: Curēus
https://read.qxmd.com/read/38507554/involvement-of-spinal-neuroplastin-65-in-neuropathic-pain-by-gabaa-receptor-%C3%AE-2-subunit-regulation
#16
JOURNAL ARTICLE
Li Xu, Yu Wang, Yang Jiao, Yulin Huang, Rui Xu, Xiaoping Gu, Wei Zhang, Zhengliang Ma
BACKGROUND: Neuropathic pain (NP) is a highly challenging condition with complex pathological mechanisms, and the spinal gamma aminobutyric acid A receptor receptor plays a crucial role in its progression. Recent studies have revealed a potential interaction between neuroplastin 65 (NP65) and gamma aminobutyric acid A receptor α2 subunit (GABAAR-α2) on the cell surface. We hypothesize that NP65 is involved in the pathogenesis of NP by regulating the level of GABAAR-α2...
March 18, 2024: Anesthesia and Analgesia
https://read.qxmd.com/read/38504555/remimazolam-for-sedation-and-anesthesia-in-children-protocol-for-a-scoping-review
#17
JOURNAL ARTICLE
Vladimir Brüggemann, Tom G Hansen
BACKGROUND: Remimazolam, a novel intravenous benzodiazepine recently approved by both the European Medicines Agency and the Food and Drug Agency, holds significant promise in clinical practice. Its pharmacodynamic profile closely mirrors that of midazolam, while its pharmacokinetics properties bear resemblance to remifentanil. Research in adult populations continues to accumulate, but the pediatric studies' pace is not significant. This scoping review aims to methodically scrutinize published studies, clinical trials, observational research, case reports, and pertinent literature to offer a comprehensive insight into the existing understanding of remimazolam in pediatric sedation and anesthesia...
March 19, 2024: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/38504037/ambulatory-total-hip-and-knee-arthroplasty-a-literature-review-and-perioperative-considerations
#18
JOURNAL ARTICLE
Vivian H Y Ip, Vishal Uppal, Kwesi Kwofie, Ushma Shah, Patrick B Y Wong
PURPOSE: Total joint arthroplasty (TJA), particularly for the hip and knee, is one of the most commonly performed surgical procedures. The advancement/evolution of surgical and anesthesia techniques have allowed TJA to be performed on an ambulatory/same-day discharge basis. In this Continuing Professional Development module, we synthesize the perioperative evidence that may aid the development of successful ambulatory TJA pathways. SOURCE: We searched MEDLINE, Embase, CENTRAL, and the Cochrane Database of Systematic Reviews for ambulatory or fast-track TJA articles...
March 19, 2024: Canadian Journal of Anaesthesia
https://read.qxmd.com/read/38498317/the-effects-of-prophylactic-use-of-esketamine-on-postoperative-depression-and-quality-of-life-a-meta-analysis
#19
JOURNAL ARTICLE
Guoweng Niu, Xiaozhu Zheng, Bigao Deng, Yong S DU, Yang Mei
INTRODUCTION: The aim of this systemic review and meta-analysis was to assess the impact of prophylactic use of esketamine on postoperative depression and quality of life in patients. EVIDENCE ACQUISITION: We searched for all articles on esketamine in patients after surgury in electronic data bases, including PubMed, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science, up to the June 2023.The included studies compared the impact of using esketamine and placebo on postoperative depression and quality of life in patients through randomized controlled trials...
March 18, 2024: Minerva Anestesiologica
https://read.qxmd.com/read/38495580/outcomes-of-operatively-managed-periprosthetic-distal-femur-fractures-compared-to-fractures-in-patients-with-native-knees
#20
JOURNAL ARTICLE
Nicholas Bostrom, Thomas Z Paull, Mai P Nguyen
INTRODUCTION: With the increasing incidence of total knee arthroplasty (TKA), there is an expected rise in rate of periprosthetic fractures in the coming years. It is unclear how the outcomes of patients with distal femur fractures (DFF) and a total knee arthroplasty compare to patients of the same age group with native knees (NK). MATERIALS AND METHODS: A retrospective review was completed for distal femur fractures treated with surgical fixation from January 2019-March 2021...
July 2024: Journal of Orthopaedics
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