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Mojtaba Heydari, Hosein Heydari, Alireza Saadati, Mohammad Gharehbeglou, Javad Tafaroji, Abolfazl Akbari
ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Medicine (TM) is popularly used for neonatal jaundice in Iran. OBJECTIVE: to provides evidence for characteristics of traditional medicine use in the treatment of neonatal jaundice in Qom, Iran. MATERIALS AND METHODS: Field surveys were carried out during July 2015 - August 2015 in Qom through structured questionnaire in Persian from 212 parents of children with neonatal jaundice. All plant species recorded for the treatment of neonatal jaundice were sampled...
October 6, 2016: Journal of Ethnopharmacology
Yasemin Sahan, Ozan Gurbuz, Metin Guldas, Nurcan Degirmencioglu, Aynur Begenirbas
In this study, the changes in phenolics, anthocyanin, antioxidant capacity, and bioaccessibility of chicory varieties (Cichorium spp.) in Turkey were investigated. A total of 19 phenolic standards were screened in the chicory varieties studied and the most abundant compounds in the samples, extracted with methanol, were phenolic acids, syringic (2.54mg/kg) and trans-ferulic acid (1.85mg/kg), whilst (+)-catechin was the major flavanol. The highest flavanol content using either methanol or ethanol was determined in the green chicory samples (0...
February 15, 2017: Food Chemistry
Katherine A Orford, Phil J Murray, Ian P Vaughan, Jane Memmott
Grassland for livestock production is a major form of land use throughout Europe and its intensive management threatens biodiversity and ecosystem functioning in agricultural landscapes. Modest increases to conventional grassland biodiversity could have considerable positive impacts on the provision of ecosystem services, such as pollination, to surrounding habitats.Using a field-scale experiment in which grassland seed mixes and sward management were manipulated, complemented by surveys on working farms and phytometer experiments, the impact of conventional grassland diversity and management on the functional diversity and ecosystem service provision of pollinator communities were investigated...
June 2016: Journal of Applied Ecology
Filip Trnka, Robert Stejskal, Jiří Skuhrovec
The mature larvae and pupae of Lixus (Ortholixus) bituberculatus Smreczyński, 1968 and Lixus (Dilixellus) neglectus Fremuth, 1983 (Curculionidae: Lixinae: Lixini) are described and compared with known larvae of 21 other Lixus and 2 Hypolixus taxa. The mature larva and pupa of Lixus bituberculatus are the first immature stages described representing the subgenus Ortholixus. The larva of Lixus neglectus, in the subgenus Dilixellus, is distinguished from the known larvae of four species in this subgenus by having more pigmented sclerites on the larval body...
2016: ZooKeys
Spyridon A Petropoulos, Efi Levizou, Georgia Ntatsi, Ângela Fernandes, Konstantinos Petrotos, Konstantinos Akoumianakis, Lillian Barros, Isabel C F R Ferreira
Soil salinization is an increasing problem for many areas throughout the world that renders prohibitive vegetables and crop production in general. In the present study, Cichorium spinosum L. plants were grown under saline conditions in order to evaluate chemical composition and bioactive compounds content of their leaves. Salinity increase resulted in significant changes of macro and micro-nutrients content (nutritional value, sugars, fatty acids, minerals, ascorbic acid and tocopherols), whereas the concentration of phenolic compounds was not significantly affected...
January 1, 2017: Food Chemistry
Feifei Wei, Kazuo Furihata, Mimin Zhang, Takuya Miyakawa, Masaru Tanokura
Roasted chicory root (Cichorium intybus) has been widely accepted as the most important coffee substitute. In this study, a nuclear magnetic resonance (NMR)-based comprehensive analysis was performed to monitor the substantial changes in the composition of chicory root during the roasting process. A detailed signal assignment of dried raw and roasted chicory roots was carried out using (1)H, (13)C, (1)H-(1)H DQF-COSY, (1)H-(13)C edited-HSQC, (1)H-(13)C CT-HMBC and (1)H-(13)C HSQC-TOCSY NMR spectra. On the basis of the signal assignments, 36 NMR-visible components were monitored simultaneously during roasting...
August 9, 2016: Journal of Agricultural and Food Chemistry
Zarrin Sarhadynejad, Fariba Sharififar, Abbas Pardakhty, Mohammad-Hadi Nematollahi, Saeedeh Sattaie-Mokhtari, Ali Mandegary
ETHNOPHARMACOLOGICAL RELEVANCE: "Zereshk-e-Saghir" (ZES), one of the traditional herbal medicines in old manuscripts of Persian hakims, has been used for the treatment of liver disorders. This current study is aimed to evaluate ZES effects on animal model to investigate its safety and hepatoprotective activity. MATERIALS AND METHODS: ZES was prepared according to a traditional method by blending aqueous extracts of Berberis vulgaris L., with fine particles of other plants including Rosa damascene Mill, Cichorium intybus L...
August 22, 2016: Journal of Ethnopharmacology
Hasan Habibi, Sobhan Firouzi, Hasan Nili, Mostafa Razavi, Seyedeh Leili Asadi, Sajad Daneshi
Safe alternative anticoccidial drug to chemical feed additives are herbal extracts, because they don't results to tissue residue and drug resistance. In order to evaluate the effects of herbal extracts to control avian coccidiosis, 180 one-day-old broiler chickens were randomly divided into nine equal groups, as follows: (1) Biarum bovei (2) Nectaroscordum tripedale( 3) Dorema aucheri (4) Cichorium intybus (5) Prangos ferulaceae (6) diclazuril (7) Artemisia absinthium (8) infected control (9) uninfected control (each contains two groups)...
June 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
Guillaume Legrand, Marianne Delporte, Chahinez Khelifi, Adeline Harant, Christophe Vuylsteker, Monika Mörchen, Philippe Hance, Jean-Louis Hilbert, David Gagneul
Chicory (Cichorium intybus) accumulates caffeic acid esters with important significance for human health. In this study, we aim at a better understanding of the biochemical pathway of these bioactive compounds. Detailed metabolic analysis reveals that C. intybus predominantly accumulates caftaric and chicoric acids in leaves, whereas isochlorogenic acid (3,5-diCQA) was almost exclusively accumulated in roots. Chlorogenic acid (3-CQA) was equally distributed in all organs. Interestingly, distribution of the four compounds was related to leaf age...
2016: Frontiers in Plant Science
Walaa G Hozayen, Mohamed A El-Desouky, Hanan A Soliman, Rasha R Ahmed, Amal K Khaliefa
BACKGROUND: Glucocorticoid-induced osteoporosis (GIO) is one of the serious side effects which have become the most common secondary osteoporosis. The purpose of this study is to evaluate the effect of aqueous extract of parsley, basil and chicory on glucocorticoid-induced osteoporosis in rats. METHODS: Fifty Female rats were divided into five groups and treated for 8 weeks as follow: group 1 served as control; group (2) subcutaneously injected with 0.1 mg/kg b...
2016: BMC Complementary and Alternative Medicine
Chaoqun Liu, Wenting Wang, Weiqun Lin, Wenhua Ling, Dongliang Wang
SCOPE: Chicory (Cichorium intybus L. var. foliosum, Belgian endive), a typical Mediterranean vegetable, and its constituent protocatechuic acid (PCA) can inhibit established atherosclerosis progression. We thus investigated whether chicory can improve vascular relaxation, a critical pathway for combating atherosclerosis, and whether PCA is a contributor to a chicory-induced effect. METHODS AND RESULTS: Apolipoprotein E-deficient (ApoE(-/-) ) mice with established atherosclerosis and C57BL/6J mice without atherosclerosis were fed an AIN-93G diet, or AIN-93G plus 0...
May 28, 2016: Molecular Nutrition & Food Research
Vincent Brieudes, Apostolis Angelis, Konstantina Vougogiannopoulou, Harris Pratsinis, Dimitris Kletsas, Sofia Mitakou, Maria Halabalaki, Leandros A Skaltsounis
The Cretan diet, as the basis of the Mediterranean diet, has provided traditional remedies for the general well being of people through the long-established consumption of cooked wild greens and vegetables. The intake of the water decoctions of Cichorium spinosum and Cichorium intybus in the context of the daily dietary regime in Greece has been long associated with "liver detoxifying" properties. In the current study, we performed an in-depth investigation of the water decoctions traditionally prepared from C...
July 2016: Planta Medica
Miguel Peña-Espinoza, Stig M Thamsborg, Olivier Desrues, Tina V A Hansen, Heidi L Enemark
Two experiments studied the effects of dietary chicory against gastrointestinal nematodes in cattle. In Experiment (Exp.) 1, stabled calves were fed chicory silage (CHI1; n = 9) or ryegrass/clover hay (CTL1; n = 6) with balanced protein/energy intakes between groups. After 16 days, all calves received 10 000 Ostertagia ostertagi and 66 000 Cooperia oncophora third-stage larvae (L3) [day (D) 0 post-infection (p.i.)]. In Exp. 2, calves were assigned to pure chicory (CHI2; n=10) or ryegrass/clover (CTL2; n = 10) pastures...
September 2016: Parasitology
Emmanuel A Tzortzakakis, Carolina Cantalapiedra-Navarrete, Antonio Archidona-Yuste, Juan E Palomares-Rius, Pablo Castillo
Members of the genus Scutellonema can cause substantial crop losses to ornamental and cultivated plants directly by feeding ectoparasitically on plant roots (Bridge et al., 2005; Coyne et al., 2006). In May 2015, a soil sample from a house garden from Heraklion city in Crete, Greece, was sent for diagnosis of plant-parasitic nematodes. In this place, there had been cactus (Opuntia sp.) plants (probably imported), which were uprooted 3 to 4 years earlier. After that, the area was cropped with cucumber (Cucumis sativus L...
March 2016: Journal of Nematology
P M B G Maia Campos, D G Mercurio, M O Melo, B Closs-Gonthier
During the aging process, the human skin suffers many alterations including dryness, skin barrier function damage. The skin barrier function is important to the prevention of skin alterations and maintenance of homeostasis. So, the objective of this study was to assess the clinical efficacy on skin barrier function of Cichorium intybus root extract in cosmetic formulations with or without UV filters. Fifty women, aged between 45 and 60 years, were divided into two groups. One group received vehicle formulations containing UV filters, and the other group received formulations without UV filters...
May 10, 2016: Journal of Dermatological Treatment
Lingpeng Zhu, Chen Nang, Fen Luo, Hong Pan, Kai Zhang, Jingyan Liu, Rui Zhou, Jin Gao, Xiayun Chang, He He, Yue Qiu, Jinglei Wang, Hongyan Long, Yu Liu, Tianhua Yan
Esculetin is one of the major bioactive compounds of Cichorium intybus L. The main purpose of the present study was to investigate the effects and possible underlying mechanism of esculetin (Esc) on lipopolysaccharide (LPS)-induced neuroinflammatory processes and depressive-like behavior in mice. Mice were pretreatment with esculetin (Esc, 20, 40mg/kg, intragastric administration) and a positive control drug fluoxetine (Flu, 20mg/kg, intragastric administration) once daily for 7 consecutive days. At the 7th day, LPS (0...
September 1, 2016: Physiology & Behavior
Miguel Peña-Espinoza, Ulrik Boas, Andrew R Williams, Stig M Thamsborg, Henrik T Simonsen, Heidi L Enemark
The study investigated direct anthelmintic effects of sesquiterpene lactones (SL)-containing extracts from forage chicory against free-living and parasitic stages of Ostertagia ostertagi. Freeze-dried leaves from chicory cultivars 'Spadona' and 'Puna II' were extracted using methanol/water. Total SL were further fractionated by solid-phase extraction and resulting extracts were characterised by high-performance liquid chromatography (HPLC). O. ostertagi eggs from faeces of mono-infected calves were hatched and L1 were used in a larval feeding inhibition assay (LFIA), while cultured L3 were used in a larval exsheathment inhibition assay (LEIA)...
December 2015: International Journal for Parasitology, Drugs and Drug Resistance
Seyede Nargess Sadati, Mohammad Reza Shams Ardekani, Nastaran Ebadi, Maryam Yakhchali, Azadeh Raees Dana, Fatemeh Masoomi, Mahnaz Khanavi, Farid Ramezany
One concept used in traditional Persian medicine (TPM) for multidrug therapy is that of the convoy drug (Mobadregh). According to TPM texts, convoy drugs are substances (or drugs), which facilitate the access of drugs or foods to the whole body or to specific organs. This study reviewed some convoy drugs presented in TPM, their biological effects, and their probable interactions with main drugs, considering the increased absorption through inhibition of P-glycoprotein (P-gp) efflux function, bioavailability-enhancing effects, and decreased metabolism of the main drug using electronic databases including PubMed, Scopus, ScienceDirect, and Google Scholar in November and December, 2013...
January 2016: Pharmacognosy Reviews
Do-Wan Shim, Ji-Won Han, Young-Eun Ji, Woo-Young Shin, Sushruta Koppula, Myong-Ki Kim, Tae-Kweon Kim, Pyo-Jam Park, Tae-Bong Kang, Kwang-Ho Lee
This study provides the scientific basis for the inhibitory effect of the aerial parts of Cichorium intybus Linn. (C. intybus) on the activation of the NLRP3 inflammasome in vitro and on high-fat diet (HFD)-induced type-2 diabetes (T2D). Lipopolysaccharide (LPS)-primed bone marrow-derived macrophages were used to study the effects methanolic extract of C. intybus leaf (CI) on inflammasome activation. An insulin resistance model (mice fed a HFD) was used to study the in vivo effect of CI on T2D. CI attenuated interleukin-1β (IL-1β) secretion by inhibiting the activation of the NLRP3 inflammasome in mouse bone marrow macrophages...
March 2016: Journal of Medicinal Food
Xue-jie Wang, Zhi-jian Lin, Bing Zhang, Chun-sheng Zhu, Hong-juan Niu, Yue Zhou, An-zheng Nie, Yu Wang
Human xanthine oxidase is considered to be a target for therapy of hyperuricemia. Cichorium intybus is a Chinese plant medicine which widely used in Xinjiang against various diseases. In order to screen the inhibitors of xanthine oxidase from C. intybus and to explore main pharmacological actions of cichory a compound collection of C. intybus was built via consulting related references about chemical research on cichory. The three-dimensional crystal structure of xanthine oxidase (PDB code: 1N5X) from Protein Data Bank was downloaded...
October 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
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