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https://www.readbyqxmd.com/read/27875034/risk-factors-of-post-traumatic-stress-symptoms-in-patients-with-cancer
#1
Yu-Hua Lin, Chia-Chan Kao, Shu-Fen Wu, Shu-Ling Hung, Hsing-Yu Yang, Hong-Yu Tung
AIM AND OBJECTIVES: To determine the level of PTSS and to identify demographics, disease history, and clinical symptoms that were associated with PTSS among gynecological, breast, or colorectal cancer patients in Taiwan. BACKGROUND: Literature indicated that 7.3 % to 35.2% of patients with cancer had experienced level of post-traumatic stress symptoms (PTSS). However, the PTSS among patients with cancer in Taiwan was not documented. DESIGN: A cross-sectional study...
November 22, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27868156/vaginal-and-sexual-health-treatment-strategies-within-a-female-sexual-medicine-program-for-cancer-patients-and-survivors
#2
Jeanne Carter, Cara Stabile, Barbara Seidel, Raymond E Baser, Shari Goldfarb, Deborah J Goldfrank
PURPOSE: We sought to evaluate patient adherence and response to simple vaginal and sexual health treatment strategies in female cancer patients receiving treatment at a female sexual medicine and health program and identify improvements of physical symptoms, per patient and clinical evaluation. METHODS: Evaluability criteria included gynecologic exam at initial visit, at least one follow-up with gynecologic exam within 8 months of initial visit, and all consecutive follow-ups <6 months apart...
November 21, 2016: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/27830448/estimating-the-effect-of-intravenous-acetaminophen-for-postoperative-pain-management-on-length-of-stay-and-inpatient-hospital-costs
#3
E Eve Shaffer, An Pham, Robert L Woldman, Andrew Spiegelman, Scott A Strassels, George J Wan, Thomas Zimmerman
INTRODUCTION: The provision of safe, effective, cost-efficient perioperative inpatient acute pain management is an important concern among clinicians and administrators within healthcare institutions. Overreliance on opioid monotherapy in this setting continues to present health risks for patients and increase healthcare costs resulting from preventable adverse events. The goal of this study was to model length of stay (LOS), potential opioid-related complications, and costs for patients reducing opioid use and adding intravenous acetaminophen (IV APAP) for management of postoperative pain...
November 9, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27815747/first-series-of-total-robotic-hysterectomy-trh-using-new-integrated-table-motion-for-the-da-vinci-xi-feasibility-safety-and-efficacy
#4
Andrea Giannini, Eleonora Russo, Paolo Mannella, Giulia Palla, Silvia Pisaneschi, Elena Cecchi, Michele Maremmani, Luca Morelli, Alessandra Perutelli, Vito Cela, Franca Melfi, Tommaso Simoncini
BACKGROUND: To present the first case series of total robotic hysterectomy (TRH), using integrated table motion (ITM), which is a new feature comprising a unique operating table by Trumpf Medical that communicates wirelessly with the da Vinci Xi surgical system. ITM has been specifically developed to improve multiquadrant robotic surgery such as that conducted in colorectal surgery. METHODS: Between May and October 2015, a prospective post-market study was conducted on ITM in the EU in 40 cases from different specialties...
November 4, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27806309/targeted-ultra-deep-sequencing-unveils-a-lack-of-driver-gene-mutations-linking-non-hereditary-gastrointestinal-stromal-tumors-and-highly-prevalent-second-primary-malignancies-random-or-nonrandom-that-is-the-question
#5
Bo-Ru Lai, Yu-Tung Wu, Yung-Chia Kuo, Hung-Chih Hsu, Jen-Shi Chen, Tse-Ching Chen, Ren-Chin Wu, Cheng-Tang Chiu, Chun-Nan Yeh, Ta-Sen Yeh
The association of non-hereditary (sporadic) gastrointestinal stromal tumors (GISTs) and second primary malignancies is known to be nonrandom, although the underlying molecular mechanisms remain unknown. In this study, 136 of 749 (18.1%) patients with sporadic GISTs were found to have additional associated cancers, with gastrointestinal and genitourinary/gynecologic/breast cancers being the most prevalent. Gene mutations in GISTs and their associated colorectal cancers (CRCs) (n=9) were analyzed using a panel of 409 cancer-related genes, while a separate group of 40 sporadic CRCs not associated with GISTs served as controls...
October 4, 2016: Oncotarget
https://www.readbyqxmd.com/read/27801734/pd-l1-expression-in-carcinosarcomas-of-the-gynecologic-tract-a-potentially-actionable-biomarker
#6
Andre Pinto, Nicholas Mackrides, Mehrdad Nadji
BACKGROUND: Carcinosarcomas of the gynecologic tract, also known as malignant mixed Müllerian tumors, are aggressive neoplasms with a high recurrence rate and poor prognosis. Despite advances in adjuvant therapies in recent years, the prognosis of these tumors has not improved. In fact, there are currently no consensus guidelines for the treatment of these neoplasms and the search for targetable biomarkers has not been successful so far. Programmed death-ligand 1 (PD-L1) has emerged as a potential target for therapeutics in a number of malignant tumors, including melanoma, lung, and colorectal cancer...
October 31, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/27753246/prospective-randomized-controlled-study-on-the-validity-and-safety-of-an-absorbable-adhesion-barrier-interceed%C3%A2-made-of-oxidized-regenerated-cellulose-for-laparoscopic-colorectal-surgery
#7
Masanori Naito, Naoto Ogura, Takahiro Yamanashi, Takeo Sato, Takatoshi Nakamura, Hirohisa Miura, Atsuko Tsutsui, Yasutoshi Sakamoto, Rieko Tanaka, Yuji Kumagai, Masahiko Watanabe
INTRODUCTION: Clinical use of an adhesion barrier made of oxidized, regenerated cellulose, Interceed®, has been reported in the field of obstetrics and gynecology to help prevent adhesions between the peritoneum and the bowel in various types of operations. In gastrointestinal surgery, sodium hyaluronate/carboxymethylcellulose has been reported as an absorbable membrane to reduce postoperative adhesions. The present study was a prospective randomized controlled study to investigate the safety and usefulness of Interceed in laparoscopic colorectal surgery...
October 18, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27743227/cancer%C3%A2-survivorship-defining-the-incidence-of-incisional-hernia-after-resection-for-intra-abdominal-malignancy
#8
Rebeccah B Baucom, Jenny Ousley, Gloria B Beveridge, Sharon E Phillips, Richard A Pierce, Michael D Holzman, Kenneth W Sharp, William H Nealon, Benjamin K Poulose
BACKGROUND: Cancer survivorship focuses largely on improving quality of life. We aimed to determine the rate of ventral incisional hernia (VIH) formation after cancer resection, with implications for survivorship. METHODS: Patients without prior VIH who underwent abdominal malignancy resections at a tertiary center were followed up to 2 years. Patients with a viewable preoperative computed tomography (CT) scan and CT within 2 years postoperatively were included...
October 14, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27682131/treatment-of-vaginal-stenosis-with-fasciocutaneous-singapore-flap
#9
Marisa M Clifton, Raffi Gurunluoglu, Javier Pizarro-Berdichevsky, Todd Baker, Sandip P Vasavada
INTRODUCTION: Vaginal stenosis is an unfortunate complication that can occur after pelvic radiation therapy for gynecologic or colorectal malignancies. Treatment is challenging and can require significant reconstructive surgery. The objective of this video is to present a case of vaginal stenosis after radiation and describe vaginal reconstruction with a fasciocutaneous Singapore flap. METHODS: We describe the case of a 42-year-old woman with a history of stage 3 colorectal cancer who underwent partial colectomy, chemotherapy, and pelvic radiation...
September 28, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27642480/-lynch-syndrome-case-report-and-review-of-the-literature
#10
Laila Bouguenouch, Imane Samri, Khadija Belhassan, Hanane Sayel, Meriame Abbassi, Sanae Bennis, Dafr Allah Benajah, Adil Ibrahimi, Afaf Amarti, Karim Ouldim
Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC) is the most common form of hereditary colorectal cancers. It increases cancer susceptibility, the risk of colorectal cancer in first-degree, endometrial cancer in women, and to a lesser extent, other cancers (ovarian, small bowel, stomach, urinary tract and hepatobiliary). Thus, the cumulative risk of developing colorectal cancer or endometrial cancer at the age of 80 years rises to 20 and 40% respectively. These cancers are characterized by a positive family history, their occurrence at an early age, and by the development of metachronous cancers in the same individual...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27621244/menopausal-hormone-therapy-in-cancer-survivors-a-narrative-review-of-the-literature
#11
REVIEW
Carol L Kuhle, Ekta Kapoor, Richa Sood, Jacqueline M Thielen, Aminah Jatoi, Stephanie S Faubion
Decision making regarding the use of menopausal hormone therapy (MHT) for the treatment of bothersome menopausal symptoms in a cancer survivor can be complex, and includes assessment of its impact on disease-free or overall survival. Estrogen receptors are present in several cancer types, but this does not always result in estrogen-mediated tumor proliferation and adverse cancer-related outcomes. Estrogen may even be protective against certain cancers. Menopausal hormone therapy is associated with an increased risk of recurrence and mortality after diagnosis of some cancer types, but not others...
October 2016: Maturitas
https://www.readbyqxmd.com/read/27553580/women-with-endometriosis-have-higher-comorbidities-analysis-of-domestic-data-in-taiwan
#12
Sen-Wen Teng, Huann-Cheng Horng, Chi-Hong Ho, Ming-Shyen Yen, Hsiang-Tai Chao, Peng-Hui Wang
Endometriosis, defined by the presence of viable extrauterine endometrial glands and stroma, can grow or bleed cyclically, and possesses characteristics including a destructive, invasive, and metastatic nature. Since endometriosis may result in pelvic inflammation, adhesion, chronic pain, and infertility, and can progress to biologically malignant tumors, it is a long-term major health issue in women of reproductive age. In this review, we analyze the Taiwan domestic research addressing associations between endometriosis and other diseases...
August 20, 2016: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/27551774/asking-the-right-questions-to-get-the-right-answers-using-cognitive-interviews-to-review-the-acceptability-comprehension-and-clinical-meaningfulness-of-patient-self-report-adverse-event-items-in-oncology-patients
#13
Patricia Holch, Lorraine Warrington, Barbara Potrata, Lucy Ziegler, Ceri Hector, Ada Keding, Clare Harley, Kate Absolom, Carolyn Morris, Leon Bamforth, Galina Velikova
BACKGROUND: Standardized reporting of treatment-related adverse events (AE) is essential in clinical trials, usually achieved by using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) reported by clinicians. Patient-reported adverse events (PRAE) may add value to clinician assessments, providing patient perspective on subjective toxicity. We developed an online patient symptom report and self-management system for real-time reporting and managing AE during cancer treatment integrated with electronic patient records (eRAPID)...
August 23, 2016: Acta Oncologica
https://www.readbyqxmd.com/read/27535758/prevalence-of-lynch-syndrome-in-unselected-patients-with-endometrial-or-ovarian-cancer
#14
Karin Kast, Catharina Dobberschütz, Carolin Eva Sadowski, Steffen Pistorius, Pauline Wimberger
INTRODUCTION: Lynch syndrome is known by healthcare providers mainly for patients with colorectal cancer. Awareness of other associated tumors, such as endometrial or ovarian cancer, is low. This study aimed to analyze the prevalence of Lynch syndrome in unselected patients with endometrial or ovarian cancer. In addition, the willingness of patients and family members to undergo germline mutation testing was investigated. METHODS: The medical records of all patients diagnosed with endometrial or ovarian cancer at the Department of Gynecology and Obsterics, University Hospital Dresden, between 1998 and 2012, were screened for a family history of HNPCC-associated cancer...
August 18, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27509022/background-colonic-18f-fluoro-2-deoxy-d-glucose-uptake-on-positron-emission-tomography-is-associated-with-the-presence-of-colorectal-adenoma
#15
Ko Eun Lee, Chang Mo Moon, Hai-Jeon Yoon, Bom Sahn Kim, Ji Young Chang, Hyo Moon Son, Min Sun Ryu, Seong-Eun Kim, Ki-Nam Shim, Hye-Kyung Jung, Sung-Ae Jung
18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) scan is used to evaluate various kinds of tumors. While most studies on PET findings of the colon focus on the colonic uptake pattern, studies regarding background colonic uptake on PET scan are rare. The purpose of this study was to identify the association between the background colonic uptake and the presence of colorectal adenoma (CRA), which is a frequent precancerous lesion. We retrospectively reviewed the medical records of 241 patients with gynecologic malignancy who had received PET or PET/computed tomography (CT) scan and colonoscopy at the same period as a baseline evaluation...
2016: PloS One
https://www.readbyqxmd.com/read/27505184/indeterminate-but-likely-unimportant-extracolonic-findings-at-screening-ct-colonography-c-rads-category-e3-incidence-and-outcomes-data-from-a-clinical-screening-program
#16
B Dustin Pooler, David H Kim, Perry J Pickhardt
OBJECTIVE: The purpose of this study was to analyze the incidence and outcomes of unsuspected indeterminate but likely unimportant extracolonic findings (CT Colonography Reporting and Data System [C-RADS] category E3) at screening CT colonography (CTC). MATERIALS AND METHODS: Over 99 months (April 2004 through June 2012), 7952 consecutive adults without symptoms of colorectal cancer (4277 women, 3675 men; mean age ± SD, 56.7 ± 7.3 years) underwent first-time screening CTC...
November 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27495281/laparoscopic-anterior-resection-with-transvaginal-specimen-extraction-tvse-for-colorectal-cancer-and-concomitant-total-hysterectomy-and-bilateral-salpingo-oophrectomy-thbso-a-technical-description
#17
Chun-Han Nigel Tan, Choon-Seng Chong, Yoke-Fai Fong, Shakina Rauff, Ker-Kan Tan
BACKGROUND: Natural orifice specimen extraction (NOSE) has evolved to circumvent the need for a specimen extraction site. Transvaginal specimen extraction (TVSE) for colorectal disease has been shown to be safe and feasible in selected cases.1 (,) 2 We describe our technique of TVSE in a case of laparoscopic ultra-low anterior resection (ULAR) with defunctioning ileostomy (DI) with a concomitant total hysterectomy and bilateral salpingo-oophrectomy (THBSO). METHODS AND RESULTS: A 74-year-old Chinese female was diagnosed with a mid-rectal cancer following colonoscopic evaluation for a change in bowel habits...
August 5, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27456544/the-use-of-coffee-chewing-gum-and-gastrograffin-in-the-management-of-postoperative-ileus-a-review-of-current-evidence
#18
Diego Flores-Funes, Álvaro Campillo-Soto, Enrique Pellicer-Franco, José Luis Aguayo-Albasini
Postoperative ileus is one of the main complications in the postoperative period. New measures appeared with the introduction of «fast-track surgery» to accelerate recovery: coffee, chewing gum and gastrograffin. We performed a summary of current evidence, reviewing articles from MEDLINE, Cochrane Database of Systematic Reviews, ISI Web of Science, and SCOPUS databases. Employed search terms were «postoperative ileus» AND («definition» OR «epidemiology» OR «risk factors» OR «Management»). We selected 44 articles: 9 systematic reviews 11 narrative reviews, 13 randomized clinical trials, 6 observational studies, and the remaining 5 scientific letters, assumptions, etc...
July 22, 2016: Cirugía Española
https://www.readbyqxmd.com/read/27343313/posterior-pelvic-exenteration-and-retrograde-total-hysterectomy-in-patients-with-locally-advanced-ovarian-cancer-clinical-and-functional-outcome
#19
Roberto Berretta, Federico Marchesi, Lavinia Volpi, Giulio Ricotta, Michela Monica, Giulio Sozzi, Maurizio Di Serio, Daniele Mautone
OBJECTIVE: To evaluate clinical outcomes and postoperative quality of life in patients affected by locally advanced ovarian cancer who underwent pelvic posterior exenteration with Hudson-Delle Piane radical retrograde hysterectomy. MATERIALS AND METHODS: Our study was done on a retrospective cohort using data from 22 patients who underwent surgery between 2010 and 2014 at the Gynecological Oncologic Center of Parma, Parma, Italy. RESULTS: Residual disease after surgery (Sugarbacker index) was absent (CC-0) in 68% of cases...
June 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27338579/risks-of-subsequent-abdominal-operations-after-laparoscopic-ventral-hernia-repair
#20
Puraj P Patel, Michael W Love, Joseph A Ewing, Jeremy A Warren, William S Cobb, Alfredo M Carbonell
INTRODUCTION: Laparoscopic ventral hernia repair (LVHR) with intraperitoneal mesh placement is well established; however, the fate of patients requiring future abdominal operations is not well understood. This study identifies the characteristics of LVHR patients undergoing reoperation and the sequelae of reoperation. METHODS: A retrospective review of a prospectively maintained database at a hernia referral center identified patients who underwent LVHR between 2005 and 2014 and then underwent a subsequent abdominal operation...
June 23, 2016: Surgical Endoscopy
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