mixedema treatment

Preoperative evaluation of patients with thyroid land disease, in any kind of surgery, should include the possibility of difficult intubation caused by thyromegaly, the hormonal status (its disbalance), as well as the screening, and therapy of consequences of thyroid imbalance on specific organ systems, especially cardiovascular. It is necessary to select the adequate anesthetics and other pharmacological agents, according to current hormonal status. It is also necessary to select the adequate medications and other therapeutic measures for prevention and treatment of possible complications in perioperative period, some of which are life-threatening (thyroid storm and mixedema coma)...

Trans-placental passage of amiodarone has not yet been demonstrated, even if it has been suspected from the observation of some cases of congenital mixedema in babies born of amiodarone-treated women. A pregnant woman, suffering from recurrent episodes of resistant high frequency, 1:1 atrial tachycardia, with severe hypotension, was treated with oral amiodarone 200 mg daily during the last three months of pregnancy. The arrhythmia was satisfactorily controlled and pregnancy was carried on well. At birth, the baby was normal on physical examination and routine blood exams...