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Vitamin B2

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https://www.readbyqxmd.com/read/29299926/hydrophilic-multi-template-molecularly-imprinted-biopolymers-based-on-a-green-synthesis-strategy-for-determination-of-b-family-vitamins
#1
Abbas Ostovan, Mehrorang Ghaedi, Maryam Arabi, Qian Yang, Jinhua Li, Lingxin Chen
A novel green synthesis strategy was proposed for preparation of multi-template molecularly imprinted biopolymers (mt-MIBP) in aqueous media with less consumption of organic solvents, which were subsequently used as sorbents of ultrasound-assisted dispersive solid-phase extraction (d-SPE) for simultaneous recognition and efficient separation of B-family vitamins in juice samples followed by high performance liquid chromatography (HPLC) determination. The obtained mt-MIBP was fully characterized by SEM, FT-IR, TEM and BET...
January 4, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29298833/production-of-il-17-by-mait-cells-is-increased-in-multiple-sclerosis-and-is-associated-with-il-7-receptor-expression
#2
Anne Willing, Jan Jäger, Stefanie Reinhardt, Nina Kursawe, Manuel A Friese
Multiple sclerosis (MS) is a T cell-driven inflammatory disease of the CNS. Research on T cell subsets involved in MS pathogenesis has mainly focused on classical CD4+ T cells, especially Th17 cells, as they produce the proinflammatory, MS-associated cytokine IL-17. However, the abundant unconventional mucosal-associated invariant T (MAIT) cells are also able to produce IL-17. MAIT cells are characterized by high CD161 expression and a semi-invariant Vα7.2 TCR, with which they recognize bacterial and yeast Ags derived from the riboflavin (vitamin B2) metabolism...
January 3, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29298649/an-inflammation-related-nutrient-pattern-is-associated-with-both-brain-and-cognitive-measures-in-a-multiethnic-elderly-population
#3
Yian Gu, Jennifer J Manly, Richard P Mayeux, Adam M Brickman
BACKGROUND: Accumulating evidence suggest that dietary factors are associated with Alzheimer's disease, and brain and cognitive health. It is unclear whether inflammation explains this association. OBJECTIVE: To examine whether an inflammation-related nutrient pattern (INP) was associated with neuroimaging and cognitive measures of brain health. METHOD: The current cross-sectional study included 330 non-demented elderly (mean age 79 years at MRI scan) participants in a multi-ethnic, community-based cohort study who had information on nutritional intakes (estimated from food frequency questionnaire), circulating C-reactive protein and interleukin-6 (measured by ELISA), MRI scans, and cognition...
January 1, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29296550/comparison-of-transepithelial-corneal-crosslinking-with-epithelium-off-crosslinking-epithelium-off-cxl-in-adult-pakistani-population-with-progressive-keratoconus
#4
Bushra Akbar, Rana Intisar-Ul-Haq, Mazhar Ishaq, Ayesha Fawad, Sabahat Arzoo, Kashif Siddique
PURPOSE: The purpose of this study is to compare the safety and efficacy of transepithelial corneal crosslinking (CXL) with epithelium-off crosslinking (epithelium-off CXL) in the treatment of progressive keratoconus in adult Pakistani population. MATERIALS AND METHODS: Sixty-four eyes of 64 consecutive patients of progressive keratoconus were included in this quasi-experimental study. Thirty-two eyes received transepithelial CXL with Peschke TE (0.25% riboflavin (Vitamin B2), 1...
October 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29296267/optimization-of-effective-minerals-on-riboflavin-production-by-bacillus-subtilis-subsp-subtilis-atcc-6051-using-statistical-designs
#5
Marjan Oraei, Seyed Hadi Razavi, Faramarz Khodaiyan
Background: Riboflavin (vitamin B2) is an essential component of the basic metabolism, and an important nutritional and growth factor in humans, animals, plants and micro-organisms. It has been widely used in the fields of pharmaceuticals, feed and food additives. The industrial production of riboflavin mostly relies on the microbial fermentation. Designing an appropriate fermentation medium is of crucial importance to improve the riboflavin production. Methods: In this study, sequential methodology combining a screening test of minerals by Plackett-Burman (PB) and an optimization test by Central Composite Design (CCD) was applied to enhance riboflavin production by Bacillus subtilis ATCC 6051 in shake flasks...
January 2018: Avicenna Journal of Medical Biotechnology
https://www.readbyqxmd.com/read/29258537/gender-differences-and-typical-nutrition-concerns-of-the-diets-of-preschool-children-the-results-of-the-first-stage-of-an-intervention-study
#6
Sylwia Merkiel-Pawłowska, Wojciech Chalcarz
BACKGROUND: Nutrition in children has an important influence on health both in childhood and adulthood. Actions aimed at improving children's nutrition are essential, not only to the children and their families, but also to the whole society. The aim of the study was to present the results of nutrient intake before starting a nutrition and physical activity intervention programme, to investigate gender differences in nutrient intake and to discuss whether the preschoolers' nutrient intake is similar to the intake of their peers from other countries...
December 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29243793/a-new-antioxidant-formulation-reduces-the-apoptotic-and-damaging-effect-of-cigarette-smoke-extract-on-human-bronchial-epithelial-cells
#7
L Vanella, G Li Volti, A Distefano, M Raffaele, V Zingales, R Avola, D Tibullo, I Barbagallo
OBJECTIVE: In this study we evaluated the possible protective effect of an antioxidant formulation containing microfiltered milk derived polypeptides, Curcumin, Vitamin B2, Carnitine and N-Acetyl-cysteine (NAC) in an in vitro model of chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS: Human bronchial epithelial cells (16HBE) were used in this study. Cells were treated for 24 h in the presence or absence of 10% of cigarette smoke extract (CSE) and in the presence or absence of antioxidant formulation...
December 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29227220/taxonomic-analyses-of-members-of-the-streptomyces-cinnabarinus-cluster-description-of-streptomyces-cinnabarigriseus-sp-nov-and-streptomyces-davaonensis-sp-nov
#8
Wiebke Landwehr, Peter Kämpfer, Stefanie P Glaeser, Christian Rückert, Jörn Kalinowski, Jochen Blom, Alexander Goesmann, Matthias Mack, Peter Schumann, Ewelina Atasayar, Richard L Hahnke, Manfred Rohde, Karin Martin, Marc Stadler, Joachim Wink
Roseoflavin is the only known riboflavin (vitamin B2) analog with antibiotic properties. It is actively taken up by many micro-organisms and targets flavinmononucleotide riboswitches and flavoproteins. It is described as the product of the tentatively named 'Streptomyces davawensis' JCM 4913. Taxonomic analysis of this strain with a polyphasic approach showed that it is very closely related to Streptomyces cinnabarinus (DSM 40467). The two Streptomyces isolates were obtained from different geographical locations (the Philippines and the Kamchatka Peninsula, respectively), their genomes have been sequenced and the question was whether or not the two isolates were representatives of the same species...
December 11, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29197046/evaluation-of-nutritional-status-post-laparoscopic-sleeve-gastrectomy-5-year-outcomes
#9
Salman Al-Sabah, Aliaa Al-Mutawa, Alfred Kojo Anderson, Mohammad Al-Mutawa
INTRODUCTION: Obesity is considered a public health problem and has led to advancements in bariatric surgery. Laparoscopic sleeve gastrectomy (LSG) had become the most performed procedure worldwide; however, its consequences on nutritional status in the short and long term are of concern. METHODS: A retrospective analysis of medical records and bariatric database of patients who underwent LSG from October 2008-September 2015 at Al-Amiri Hospital, Kuwait, was performed...
December 1, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29185933/severe-riboflavin-deficiency-induces-alterations-in-the-hepatic-proteome-of-starter-pekin-ducks
#10
Jing Tang, Maria A Hegeman, Jian Hu, Ming Xie, Wenbiao Shi, Yong Jiang, Vincent de Boer, Yuming Guo, Shuisheng Hou, Jaap Keijer
Suboptimal vitamin B2 status is encountered globally. Riboflavin deficiency depresses growth and results in a fatty liver. The underlying mechanisms remain to be established and an overview of molecular alterations is lacking. We investigated hepatic proteome changes induced by riboflavin deficiency to explain its effects on growth and hepatic lipid metabolism. In all, 360 1-d-old Pekin ducks were divided into three groups of 120 birds each, with twelve replicates and ten birds per replicate. For 21 d, the ducks were fed ad libitum a control diet (CAL), a riboflavin-deficient diet (RD) or were pair-fed with the control diet to the mean daily intake of the RD group (CPF)...
November 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/29168736/association-between-vitamin-intake-during-pregnancy-and-risk-of-small-for-gestational-age
#11
Inmaculada Salcedo-Bellido, Juan Miguel Martínez-Galiano, Rocío Olmedo-Requena, Juan Mozas-Moreno, Aurora Bueno-Cavanillas, Jose J Jimenez-Moleon, Miguel Delgado-Rodríguez
Pregnancy increases the requirements of certain nutrients, such as vitamins, to provide nutrition for the newborn. The aim was to analyze the association between dietary intake of vitamins during pregnancy and risk of having a small for gestational age (SGA) newborn. A matched case-control study was conducted (518 cases and 518 controls of pregnant women) in Spain. Dietary vitamin intake during pregnancy was assessed using a validated food frequency questionnaire, categorized into quintiles. Odds ratios (ORs) and their 95% confidence intervals (CI) were estimated with conditional regression logistic models...
November 23, 2017: Nutrients
https://www.readbyqxmd.com/read/29166640/lactic-acid-bacteria-from-andean-grain-amaranth-a-source-of-vitamins-and-functional-value-enzymes
#12
Silvana L Carrizo, Cecilia E Montes de Oca, María Elvira Hébert, Lucila Saavedra, Graciela Vignolo, Jean Guy LeBlanc, Graciela Celestina Rollán
Amaranth is a rediscovered pseudocereal with high nutritional properties. Lactic acid fermentation can increase the functional and nutritional value of foods. The aims of this study were to isolate and evaluate the functionality of lactic acid bacteria (LAB) from amaranth. LAB strains (n = 29) isolated from amaranth sourdough and grains included Lactobacillus (L.) plantarum (n = 8), L. rhamnosus (n = 6), Enterococcus (E.) mundtii (n = 4), E. hermanniensis (n = 3), E. durans (n = 1), Enterococcus sp. (n = 1), Leuconostoc (Lc...
November 23, 2017: Journal of Molecular Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29145311/pulmonary-hypertension-as-a-manifestation-of-mitochondrial-disease-a-case-report-and-review-of-the-literature
#13
Shan Xu, Xiaoling Xu, Jisong Zhang, Kejing Ying, Yuquan Shao, Ruifeng Zhang
BACKGROUND: Mitochondrial diseases are a group of multisystem heterogeneous diseases caused by pathologic dysfunction of the mitochondrial respiratory chain. A wide range of clinical expression has been described. However, pulmonary hypertension has rarely been described in association with mitochondrial disease until the past decade, and there is no currently recognized treatment for the pulmonary hypertension complicated with mitochondrial disorder. PATIENT CONCERNS: We reported the case of a 15-year-old boy who presented with shortness of breath and exercise limitation after a cold, and the diagnosis of pulmonary hypertension was confirmed by right heart catheter...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29129231/the-association-between-the-index-of-nutritional-quality-inq-and-breast-cancer-and-the-evaluation-of-nutrient-intake-of-breast-cancer-patients-a-case-control-study
#14
Farhad Vahid, Mahshid Hatami, Mahya Sadeghi, Fatemeh Ameri, Zeinab Faghfoori, Sayed Hossein Davoodi
OBJECTIVE: Breast cancer (BrCa) is the most frequently diagnosed cancer among females and second cancer after lung cancer in many societies. In Iran, the risk for BrCa is 1 in 35 and each year, 8000 new patients have been diagnosed with BrCa. Studies have shown that dietary components are implicated in the etiology of BrCa. The Index of Nutritional Quality (INQ) is a method of quantitative and qualitative analysis of single foods, meals, and diets. The aim of this study was to determine the usefulness of INQs in predicting BrCa risk...
January 2018: Nutrition
https://www.readbyqxmd.com/read/29124435/vitamin-d-deficiency-an-unrecognized-cause-of-flank-pain
#15
Dina O Abdulazim, Mona M Salem, Mohammed Hassan, Ahmed Abdo, Esam Rashad, Usama A A Sharaf El Din
Loin pain is frequently not associated with any urinary abnormality. Musculoskeletal abnormalities are not uncommon as alternative cause of flank pain. Osteomalacia of the ribs was infrequently encountered as the cause of flank pain. Vitamin D deficiency has been reported as a common problem worldwide with special predilection to the Middle East area. In this study, we looked for vitamin D deficiency in patients with flank pain associated with tenderness over the tips of the lowermost ribs. Out of 783 patients presenting with unilateral or bilateral flank pain to a single center over a period of 3 years, 316 did not have a definite urologic cause (group B)...
November 9, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29122468/an-intronic-variation-in-slc52a1-causes-exon-skipping-and-transient-riboflavin-responsive-multiple-acyl-coa-dehydrogenation-deficiency
#16
Signe Mosegaard, Gitte Hoffmann Bruun, Karen Freund Flyvbjerg, Yngve Thomas Bliksrud, Niels Gregersen, Maja Dembic, Ellen Annexstad, Trine Tangeraas, Rikke Katrine Jentoft Olsen, Brage S Andresen
Vitamin B2, riboflavin is essential for cellular function, as it participates in a diversity of redox reactions central to human metabolism, through its role as precursor for the cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are electron carriers. The electron transfer flavoprotein (ETF) and its dehydrogenase (ETFDH), uses FAD as cofactor. The ETF and ETFDH are forming the electron transport pathway for many mitochondrial flavoprotein dehydrogenases involved in fatty acid, amino acid and choline metabolism...
November 2, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29106304/role-of-mait-cells-in-the-immunopathogenesis-of-inflammatory-diseases-new-players-in-old-game
#17
Vijay Kumar, Ali Ahmad
Current advances in immunology have led to the identification of a population of novel innate immune T cells, called mucosa-associated invariant T (MAIT) cells. The cells in humans express an invariant TCRα chain (Vα7.2-Jα33) paired with a limited subset of TCRβ chains (Vβ2, 13 and 22), are restricted by the MHC class I (MH1)-related (MR)-1, and recognize molecules that are produced in the bacterial riboflavin (vitamin B2) biosynthetic pathway. They are present in the circulation, liver and at various mucosal sites (i...
November 6, 2017: International Reviews of Immunology
https://www.readbyqxmd.com/read/29104633/echinocystic-acid-ameliorates-hyperhomocysteinemia-induced-vascular-endothelial-cell-injury-through-regulating-nf-%C3%AE%C2%BAb-and-cyp1a1
#18
Chuan-Feng Huang, Wei-Na Wang, Cheng-Cao Sun, Yu-Qing Wang, Ling Li, Yin Li, De-Jia Li
The present study investigated the role of echinocystic acid (EA) on the expression of nuclear factor (NF)-κB and cytochrome P450 1A1 (CYP1A1), and aortic morphology, in a rat model of hyperhomocysteinemia (Hhcy). A total of 50 Sprague Dawley rats were randomly divided into five groups as follows: Normal control (NC), model control (MC), vitamin control (VC; folic acid 1 mg/kg + vitamin B2 2 mg/kg + vitamin B12 10u g/kg), EA1 (20 mg/kg EA) and EA2 (40 mg/kg EA). Plasma homocysteine (Hcy) levels were determined via high performance liquid chromatography, and the morphology of the aorta was investigated using hematoxylin and eosin staining...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29101380/reduced-graphene-oxide-gold-nanoparticle-nanoframework-as-a-highly-selective-separation-material-for-aflatoxins
#19
Wenbo Guo, Lidong Wu, Kai Fan, Dongxia Nie, Weijing He, Junhua Yang, Zhihui Zhao, Zheng Han
Graphene-based materials have been studied in many applications, owing to the excellent electrical, mechanical, and thermal properties of graphene. In the current study, an environmentally friendly approach to the preparation of a reduced graphene oxide-gold nanoparticle (rGO-AuNP) nanocomposite was developed by using L-cysteine and vitamin C as reductants under mild reaction conditions. The rGO-AuNP material showed a highly selective separation ability for 6 naturally occurring aflatoxins, which are easily adsorbed onto traditional graphene materials but are difficult to be desorbed...
November 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29094631/acculturation-and-dietary-intakes-by-gender-among-mongolians-in-south-korea-nutrition-education-implication-for-multicultural-families
#20
Hae Ryun Park, Zuunnast Tserendejid, Joung Hee Lee, Young Suk Lim
We explored the relationship between acculturation and dietary intake by gender for 500 Mongolians residing in South Korea. The high acculturation (HA) group females consumed more fish and shellfish, vegetables, beans, and rice, and less meats, flours, and oil than the low acculturation (LA) group did. However, there was no statistical difference in food group intake between HA and LA group males. HA group females showed higher intake of carbohydrates, fiber, sodium, potassium, calcium, vitamin A, and folate compared with LA group females...
October 2017: Asia-Pacific Journal of Public Health
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