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https://www.readbyqxmd.com/read/28437181/isolation-of-brucella-inopinata-like-bacteria-from-white-s-and-denny-s-tree-frogs
#1
Masanobu Kimura, Yumi Une, Michio Suzuki, Eun-Sil Park, Koichi Imaoka, Shigeru Morikawa
Brucella inopinata strain BO1 and B. sp. strain BO2 isolated from human patients, respectively, are genetically different from classical Brucella species. We isolated bacteria of the genus Brucella from two species of wild-caught tropical frogs kept in the facilities in Japan: White's tree frog, which inhabits Oceania, and Denny's tree frog, which inhabits Southeast Asia. Phylogenetic analyses based on 16S rRNA and recA gene sequences and multilocus sequence analysis showed that two isolates of Brucella spp...
February 16, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28428937/intravenous-immunoglobulin-g-in-women-with-reproductive-failure-the-korean-society-for-reproductive-immunology-practice-guidelines
#2
REVIEW
Nayoung Sung, Ae Ra Han, Chan Woo Park, Dong Wook Park, Joon Cheol Park, Na Young Kim, Kyung Sil Lim, Ji Eun Shin, Chang Woo Joo, Seung Eun Lee, Jae Won Kim, Sung Ki Lee
The task force of the Korean Society for Reproductive Immunology recommends intravenous immunoglobulin G treatment in women with reproductive failure, including recurrent pregnancy loss and/or repeated implantation failure, who show cellular immune factors such as abnormal natural killer cell levels, natural killer cell cytotoxicity, and/or type 1 T helper immunity.
March 2017: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28426201/exploiting-solvate-ionic-liquids-for-amine-gas-analysis-on-a-quartz-crystal-microbalance
#3
Hsin-Yi Li, Yen-Ho Chu
We demonstrated in this work the usefulness of solvate ionic liquids, SIL 3 and SIL 4, for chemoselective detection of amine gases on a quartz crystal microbalance. This detection of gaseous amines was achieved by nucleophilic aromatic addition reactions with super electrophilic SIL 3 or SIL 4 thin-coated on quartz chips. Starting with inexpensive reagents, functional SIL 3 and SIL 4 could be readily synthesized in two short steps with high isolated yield (81% and 77%, respectively). The QCM platform developed in this work is readily applicable and highly sensitive to low molecular weight amine gases: for propylamine gas at 10 Hz decrease in resonance frequency, the sensitivity of detection using SIL 4 was 5...
April 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28422196/boundary-layer-friction-of-solvate-ionic-liquids-as-a-function-of-potential
#4
Hua Li, Mark W Rutland, Masayoshi Watanabe, Rob Atkin
Atomic force microscopy (AFM) has been used to investigate the potential dependent boundary layer friction at solvate ionic liquid (SIL)-highly ordered pyrolytic graphite (HOPG) and SIL-Au(111) interfaces. Friction trace and retrace loops of lithium tetraglyme bis(trifluoromethylsulfonyl)amide (Li(G4) TFSI) at HOPG present clearer stick-slip events at negative potentials than at positive potentials, indicating that a Li(+) cation layer adsorbed to the HOPG lattice at negative potentials which enhances stick-slip events...
April 19, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28421120/in-vitro-and-in-vivo-studies-on-quercus-acuta-thunb-fagaceae-extract-active-constituents-serum-uric-acid-suppression-and-xanthine-oxidase-inhibitory-activity
#5
In-Soo Yoon, Dae-Hun Park, Min-Suk Bae, Deuk-Sil Oh, Nan-Hui Kwon, Jung-Eun Kim, Chul-Yung Choi, Seung-Sik Cho
Quercus acuta Thunb. (Fagaceae) (QA) is cultivated as a dietary and ornamental plant in China, Japan, South Korea, and Taiwan. It has been widely used as the main ingredient of acorn tofu, a traditional food in China and South Korea. The aim of this study was to determine in vitro and in vivo xanthine oxidase (XO) inhibitory and antihyperuricemic activities of an ethyl acetate extract of QA leaf (QALE) and identify its active phytochemicals using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography (LC) systems...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28419815/diagnostic-performance-of-and-breast-tissue-changes-at-early-breast-mr-imaging-surveillance-in-women-after-breast-conservation-therapy
#6
Eun Jeong Kim, Bong Joo Kang, Sung Hun Kim, In Kyung Youn, Ji Eun Baek, Hyun Sil Lee
Purpose To investigate the diagnostic performance and tissue changes in early (1 year or less) breast magnetic resonance (MR) imaging surveillance in women who underwent breast conservation therapy for breast cancer. Materials and Methods This prospective study was approved by the institutional review board, and written informed consent was obtained. Between April 2014 and June 2016, 414 women (mean age, 51.5 years; range, 21-81 years) who underwent 422 early surveillance breast MR imaging examinations (median, 6...
April 18, 2017: Radiology
https://www.readbyqxmd.com/read/28418865/anti-helminthic-niclosamide-inhibits-ras-driven-oncogenic-transformation-via-activation-of-gsk-3
#7
Sung Yong Ahn, Ji Hye Yang, Nam Hee Kim, Kyungro Lee, Yong Hoon Cha, Jun Seop Yun, Hee Eun Kang, Yoonmi Lee, Jiwon Choi, Hyun Sil Kim, Jong In Yook
Despite the importance of Ras oncogenes as a therapeutic target in human cancer, their 'undruggable' tertiary structures limit the effectiveness of anti-Ras drugs. Canonical Wnt signaling contributes to Ras activity by glycogen synthase kinase 3 (GSK-3)-dependent phosphorylation at the C-terminus and subsequent degradation. In the accompanying report, we show that the anti-helminthic niclosamide directly binds to GSK-3 and inhibits Axin functions in colon cancer cells, with reversion of Snail-mediated epithelial-mesenchymal transition...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28418862/niclosamide-is-a-potential-therapeutic-for-familial-adenomatosis-polyposis-by-disrupting-axin-gsk3-interaction
#8
Sung Yong Ahn, Nam Hee Kim, Kyungro Lee, Yong Hoon Cha, Ji Hye Yang, So Young Cha, Eunae Sandra Cho, Yoonmi Lee, Jeong Seok Cha, Hyun Soo Cho, Yoon Jeon, Young-Su Yuk, Suebean Cho, Kyoung Tai No, Hyun Sil Kim, Ho Lee, Jiwon Choi, Jong In Yook
The epithelial-mesenchymal transition (EMT) is implicated in tumorigenesis and cancer progression, and canonical Wnt signaling tightly controls Snail, a key transcriptional repressor of EMT. While the suppression of canonical Wnt signaling and EMT comprises an attractive therapeutic strategy, molecular targets for small molecules reverting Wnt and EMT have not been widely studied. Meanwhile, the anti-helminthic niclosamide has been identified as a potent inhibitor of many oncogenic signaling pathways although its molecular targets have not yet been clearly identified...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28413914/prognostic-value-of-the-soluble-interleukin-2-receptor-level-after-patients-with-follicular-lymphoma-achieve-a-response-to-r-chop
#9
Kento Umino, Shin-Ichiro Fujiwara, Takashi Ikeda, Yumiko Toda, Shoko Ito, Kiyomi Mashima, Daisuke Minakata, Hirofumi Nakano, Ryoko Yamasaki, Yasufumi Kawasaki, Miyuki Sugimoto, Chihiro Yamamoto, Masahiro Ashizawa, Kaoru Hatano, Kazuya Sato, Iekuni Oh, Ken Ohmine, Kazuo Muroi, Yoshinobu Kanda
OBJECTIVES: Follicular lymphoma (FL) is a clinically and biologically heterogeneous disease. Therefore, it is important to identify factors that can predict its clinical outcome. METHODS: We retrospectively evaluated the usefulness of soluble interleukin-2 receptor (sIL-2R) levels after R-CHOP (posttreatment sIL-2R) in 72 patients with newly diagnosed FL who had either a complete response (CR) or partial response. With the use of a recursive partitioning analysis, we determined the cut-off values of post- and pretreatment sIL-2R levels that were associated with disease progression, which corresponded to 486...
April 17, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/28411687/oral-administration-of-red-ginseng-powder-fermented-with-probiotic-alleviates-the-severity-of-dextran-sulfate-sodium-induced-colitis-in-a-mouse-model
#10
Sun-Hee Jang, Jisang Park, Sae-Hae Kim, Kyung-Min Choi, Eun-Sil Ko, Jeong-Dan Cha, Young-Ran Lee, Hyonseok Jang, Yong-Suk Jang
Red ginseng is a well-known alternative medicine with anti-inflammatory activity. It exerts pharmacological effects through the transformation of saponin into metabolites by intestinal microbiota. Given that intestinal microflora vary among individuals, the pharmacological effects of red ginseng likely vary among individuals. In order to produce homogeneously effective red ginseng, we prepared probiotic-fermented red ginseng and evaluated its activity using a dextran sulfate sodium (DSS)-induced colitis model in mice...
March 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28408939/the-immune-effects-of-an-african-traditional-energy-tonic-in-in-vitro-and-in-vivo-models
#11
Mlungisi Ngcobo, Nceba Gqaleni, Vinny Naidoo, Protus Cele
Most of the African traditional medicines (ATM) are formulated as energy tonics to boost and maintain immune defences. In this study, we aimed to evaluate the immune effects of a traditional energy tonic using peripheral blood mononuclear cells (PBMCs), THP-1 monocytes, and bacteria infected rats. When tested in mitogen and peptidoglycan stimulated PBMCs, this energy tonic showed minimal cytotoxicity, while in acute toxicity studies in rats it did not exhibit any significant toxicity at doses up to 2000 mg/mL/kg...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28406507/achieving-yellow-emission-by-varying-the-donor-acceptor-units-in-rod-shaped-fluorenyl-alkynyl-based-%C3%AF-conjugated-oligomers-and-their-binuclear-gold-i-alkynyl-complexes
#12
Sk Najmul Islam, Amit Sil, Sanjib K Patra
Fluorenyl-alkynyl based π-conjugated rod-shaped oligomers bearing different central aromatic moieties and functionalizable di-alkynyl termini, such as H-[triple bond, length as m-dash]-Fl-[triple bond, length as m-dash]-Fl-[triple bond, length as m-dash]-Fl-[triple bond, length as m-dash]-H (OH1), H-[triple bond, length as m-dash]-Fl-[triple bond, length as m-dash]-Btz-[triple bond, length as m-dash]-Fl-[triple bond, length as m-dash]-H (OH2) and H-[triple bond, length as m-dash]-Fl-[triple bond, length as m-dash]-Btd-[triple bond, length as m-dash]-Fl-[triple bond, length as m-dash]-H (OH3) where Fl = 9,9-dioctylfluorene, Btz = N-hexylbenzotriazole, and Btd = benzothiadiazole, were successfully synthesized by a Pd(0) catalyzed Stille coupling protocol...
April 13, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28402273/serum-il-33-level-is-a-predictor-of-progression-free-survival-after-chemotherapy
#13
Wenwei Hu, Chen Wu, Xiaodong Li, Zhuojun Zheng, Quanqin Xie, Xu Deng, Jingting Jiang, Changping Wu
This study aimed to evaluate the association between of serum IL-33 (sIL-33) level in gastric cancer (GC) patients and progression-free survival (PFS). A total of 62 patients with advanced GC and 32 healthy subjects were enrolled. sIL-33 level was detected in pre-chemotherapy patients, post-chemotherapy patients and healthy subjects, respectively. sIL-33 levels were 131.9 (95% CI 105.9-184.9) pg/mL, 95.1 (95% CI 70.8-140.2) pg/mL and 95.7 (95% CI 73.3-114.3) pg/mL in pre-chemotherapy patients, post-chemotherapy patients and controls, respectively...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28401287/graphene-oxide-for-solid-phase-extraction-of-bioactive-phenolic-acids
#14
Xiudan Hou, Xusheng Wang, Yingxin Sun, Licheng Wang, Yong Guo
A solid-phase extraction (SPE) method for the efficient analysis of trace phenolic acids (PAs, caffeic acid, ferulic acid, protocatechuic acid, cinnamic acid) in urine was established. In this work, a graphene oxide (GO) coating was grafted onto pure silica to be investigated as SPE material. The prepared GO surface had a layered and wrinkled structure that was rough and well organized, which could provide more open adsorption sites. Owing to its hydrophilicity and polarity, GO showed higher extraction efficiency toward PAs than reduced GO did, in agreement with the theoretical calculation results performed by Gaussian 09 software...
April 11, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28400220/transvaginal-excision-of-an-eroded-sacrocolpopexy-mesh-by-using-the-sils-equipment
#15
Stefan Mohr, Franziska Siegenthaler, Sara Imboden, Annette Kuhn, Michael D Mueller
No abstract text is available yet for this article.
April 8, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28395939/a-case-series-of-histoplasmosis-patients-with-elevated-serum-soluble-interleukin-2-receptor-levels
#16
Tatsuro Hirayama, Takahiro Takazono, Kazuma Iwata, Hiroaki Senju, Takaharu Shimazaki, Masato Tashiro, Tomomi Saijo, Takeshi Tanaka, Shigeki Nakamura, Yoshifumi Imamura, Maiko Kojiro, Taiga Miyazaki, Misuzu Tsukamoto, Akitsugu Furumoto, Konosuke Morimoto, Yasunori Muraosa, Yuichi Matsubara, Katsunori Yanagihara, Hiroshi Mukae, Katsuhiko Kamei, Shigeru Kohno, Koichi Izumikawa
Histoplasmosis is a common endemic mycosis that is usually asymptomatic but occasionally results in severe illness. Histoplasmosis and its causative agent, Histoplasma capsulatum, are found worldwide but rarely in Japan. In recent years, however, the number of histoplasmosis patients in Japan has increased. In addition, to our knowledge, there are no previous reports of increased serum soluble interleukin-2 receptor (sIL-2R) levels in patients with histoplasmosis. We report a case series of histoplasmosis in three Japanese temporary workers in Manzanillo, Mexico...
April 8, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28395502/reirradiation-of-head-and-neck-cancer-in-the-era-of-intensity-modulated-radiotherapy-patient-selection-practical-aspects-and-current-evidence
#17
REVIEW
Yeon Sil Kim
Locoregional failure is the most frequent pattern of failure in locally advanced head and neck cancer patients and it leads to death in most of the patients. Second primary tumors occurring in the other head and neck region reach up to almost 40% of long-term survivors. Recommended and preferred retreatment option in operable patients is salvage surgical resection, reporting a 5-year overall survival of up to 40%. However, because of tumor location, extent, and underlying comorbidities, salvage surgery is often limited and compromised by incomplete resection...
March 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28393817/efficacy-of-triphala-extract-and-chlorhexidine-mouth-rinse-against-plaque-accumulation-and-gingival-inflammation-among-female-undergraduates-a-randomized-controlled-trial
#18
Sahana Umesh Baratakke, Rekha Raju, Sushi Kadanakuppe, Nagashree R Savanur, Radha Gubbihal, Pallavi Swamy Kousalaya
AIM: To know the efficacy of Triphala extract and Chlorhexidine mouth rinse against plaque and gingival inflammation. MATERIALS AND METHODS: A double blinded parallel arm randomised control trial was done among 60 participants aged 18-24 years. Participants were randomly allotted to three groups with 20 participants in each group of 0.6% triphala, 0.12% chlorhexidine and control group. Study was done in 2 phases of 21 days duration. During the experimental period, participants rinsed with the allocated mouth rinse 10ml twice daily for 30 seconds without any supervision...
January 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28390205/comparative-efficacy-of-a-soft-toothbrush-with-tapered-tip-bristles-and-an-ada-reference-toothbrush-on-established-gingivitis-and-supragingival-plaque-over-a-12-week-period
#19
John Gallob, Dolores M Petrone, Luis R Mateo, Patricia Chaknis, Boyce M Morrison, Malcolm Williams, Foti Panagakos
OBJECTIVES: Evaluation of the efficacy of a soft toothbrush with tapered-tip bristles (Test Toothbrush) and an ADA reference soft toothbrush (ADA Toothbrush) on established gingivitis and supragingival plaque over a 12-week period. METHODS: This randomized, single-center, examiner-blind, two-cell, parallel clinical research study assessed plaque removal by the comparison of pre- to- post-brushing after a single use, and again after six- and 12-weeks' use, using the Quigley-Hein Plaque Index, Turesky Modification...
June 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390199/efficacy-of-dentaq%C3%A2-oral-and-ent-health-probiotic-complex-on-clinical-parameters-of-gingivitis-in-patients-undergoing-fixed-orthodontic-treatment-a-pilot-study
#20
Duygu Kolip, Nuray Yılmaz, Berna Gökkaya, Pinar Kulan, Betul Kargul, Kyle W MacDonald, Peter A Cadieux, Jeremy P Burton, Kris M James
OBJECTIVES: Probiotics act as a unique approach to maintaining oral health by supplementing the endogenous oral bacteria with additional naturally occurring beneficial microbes to provide defense against pathogens harmful to teeth and gingiva. The aim of this pilot study was to clinically evaluate the effects of probiotics on plaque accumulation and gingival inflammation in subjects with fixed orthodontics. METHODS: The pilot study was comprised of 15 healthy patients, aged 11 to 18 years, undergoing fixed orthodontic treatment...
September 2016: Journal of Clinical Dentistry
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