Read by QxMD icon Read

Triple rule-out

Alhadji Malloum, Jean Jules Fifen, Zoubeida Dhaouadi, Serge Guy Nana Engo, Nejm-Eddine Jaidane
The accurate determination of the solvation energies of a proton in ammonia is based on the precise knowledge of the structures of neutral and protonated ammonia clusters. In this work, we have investigated all the possible and stable structures of protonated ammonia clusters H(+)(NH3)n=2-9, along with their isomeric distribution at a specific temperature. New significant isomers are reported here for the first time and show that the structures of protonated ammonia clusters are not only branched linear as assumed by all previous authors...
September 29, 2016: Physical Chemistry Chemical Physics: PCCP
Richard A P Takx, Radko Krissak, Christian Fink, Valentin Bachmann, Thomas Henzler, Mathias Meyer, John W Nance, Stefan O Schoenberg, Paul Apfaltrer
OBJECTIVES: To investigate the relationship between image quality and patient size at 100 kilovoltage (kV) compared to 120 kV ECG-gated Triple-Rule-Out CT angiography (TRO-CTA). METHODS: We retrospectively included 73 patients (age 64 ± 14 years) who underwent retrospective ECG-gated chest CTA. 40 patients were scanned with 100 kV while 33 patients with 120 kV. Body mass index (BMI), patients' chest circumference (PC) and thoracic surface area (TSA) were recorded...
September 29, 2016: European Radiology
Matheus Bertanha, Paula Angeleli Bueno de Camargo, Regina Moura, Winston Bonetti Yoshida, Rafael Elias Farres Pimenta, Jamil Victor de Oliveira Mariúba, Giovana Piteri Alcantara, Dênia Reis de Paula, Marcone Lima Sobreira
BACKGROUND: Telangiectasias are defined as small venules abnormally dilated, located in the intradermal portion of the skin, of reddish or bluish tinge, their diameter not exceeding 1 mm; they are classified by the American Venous Forum as mild venous disease CEAP C1. Conventional treatment consists of chemical sclerotherapy, considered a minimally invasive technique with rapid clinical recovery. A wide variety of sclerosing solutions can be used for this purpose. METHODS/DESIGN: This project intends to include 96 patients that will be randomized to a triple-blind study...
September 2016: Medicine (Baltimore)
Hyun Su Kim, Sung Mok Kim, Min Jae Cha, Yoo Na Kim, Hae Jin Kim, Jin-Ho Choi, Yeon Hyeon Choe
BACKGROUND: Triple rule-out computed tomography (TRO CT) is a CT protocol designed to simultaneously evaluate the coronary, aorta, and pulmonary arteries. PURPOSE: To evaluate potential diagnostic performance of TRO CT with restricted volume coverage for detection of pulmonary thromboembolism (PTE) and aortic dissection (AD). MATERIAL AND METHODS: This study included 1224 consecutive patients with acute chest pain who visited the emergency department and underwent TRO CT using a 128-slice dual-source CT...
August 22, 2016: Acta Radiologica
Suriya Plernsub, Jassada Saingamsook, Jintana Yanola, Nongkran Lumjuan, Pongsri Tippawangkosol, Kom Sukontason, Catherine Walton, Pradya Somboon
BACKGROUND: Mutation in the voltage-gated sodium channel gene that results in knockdown resistance (kdr), is a major mechanism of pyrethroid resistance in several mosquito species. In Aedes aegypti, V1016G (occurring with and without S989P) and F1534C mutations are common and widely distributed throughout Asia. The G1016 allele is known to be associated with resistance to type I and II pyrethroids. The C1534 allele is primarily associated with resistance to type I pyrethroids and is known to be a recessive allele in conferring kdr...
2016: Parasites & Vectors
Minjung Kathy Chae, Eun Kyoung Kim, Ka-Young Jung, Tae Gun Shin, Min Seob Sim, Ik-Joon Jo, Keun Jeong Song, Sung-A Chang, Young Bin Song, Joo-Yong Hahn, Seung Hyuk Choi, Hyeon-Cheol Gwon, Sang-Hoon Lee, Sung Mok Kim, Hong Eo, Yeon Hyeon Choe, Jin-Ho Choi
AIMS: Clinical evidence supporting triple rule-out computed tomography (TRO-CT) for rapid screening of cardiovascular disease is limited. We investigated the clinical value of TRO-CT in patients with acute chest pain. METHODS: We retrospectively enrolled 1024 patients who visited the emergency department (ED) with acute chest pain and underwent TRO-CT using a 128-slice CT system. TRO-CT was classified as "positive" if it revealed clinically significant cardiovascular disease including obstructive coronary artery disease, pulmonary thromboembolism, or acute aortic syndrome...
July 2016: Journal of Cardiovascular Computed Tomography
Christian T Braun, Meret E Ricklin, Aristomenis K Exadaktylos
We present a rare case of severe ischaemic papillary muscle rupture in a 67-year-old male patient who was admitted to the Emergency Department of the University Hospital Bern, Switzerland, in November 2013 with acute chest pain. On admission, the patient's blood pressure was 60/40 mm/Hg, his pulse was 110 beats per minute and his respiratory rate was 20 breaths per minute. An electrocardiogram was normal and focused assessment with sonography in trauma was negative. Transthoracic echocardiography showed possible thickening of the mitral valve leaflet with no indications of severe mitral insufficiency or wall motion abnormalities...
May 2016: Sultan Qaboos University Medical Journal
Xudong Wu, Artur A Indzhykulian, Paul D Niksch, Roxanna M Webber, Miguel Garcia-Gonzalez, Terry Watnick, Jing Zhou, Melissa A Vollrath, David P Corey
Members of the TRP superfamily of ion channels mediate mechanosensation in some organisms, and have been suggested as candidates for the mechanotransduction channel in vertebrate hair cells. Some TRP channels can be ruled out based on lack of an inner ear phenotype in knockout animals or pore properties not similar to the hair-cell channel. Such studies have excluded Trpv4, Trpa1, Trpml3, Trpm1, Trpm3, Trpc1, Trpc3, Trpc5, and Trpc6. However, others remain reasonable candidates. We used data from an RNA-seq analysis of gene expression in hair cells as well as data on TRP channel conductance to narrow the candidate group...
2016: PloS One
Angelo Valetto, Veronica Bertini, Angela Michelucci, Benedetta Toschi, Eleonora Dati, Giampietro I Baroncelli, Silvano Bertelloni
Short stature homeobox gene (SHOX) mutations and pseudoautosomal region 1 (PAR1) deletions encompassing SHOX are known causes of Léri-Weill dyschondrosteosis and isolated short stature, while 3 copies of SHOX in cases with triple sex chromosome constitution are responsible for tall stature. Duplications involving SHOX have been rarely reported, and they were found in individuals with short, normal and tall stature. An adopted boy with short stature, isodicentric Y chromosome and 3 copies of SHOX is described...
April 2016: Molecular Syndromology
Amelia M Wnorowski, Ethan J Halpern
OBJECTIVE: The objective of the present study is to quantify the diagnostic yield of triple-rule-out (TRO) CT for the evaluation of acute chest pain in emergency department patients. MATERIALS AND METHODS: All TRO CT studies performed at our institution from 2006 to 2015 were reviewed. Scans were performed on a 256-MDCT scanner, with the use of ECG gating and a biphasic contrast injection. Radiology reports were reviewed to identify diagnoses that could explain chest pain, including coronary and noncoronary diagnoses, and significant incidental findings that did not account for the patient's presentation...
August 2016: AJR. American Journal of Roentgenology
G M Buzás
Carcinoma antigen 72-4 is a cell surface glycoprotein produced by gastric carcinoma cells. In the case presented, Helicobacter pylori infection induced an inappropriate elevation of this tumour antigen in a 66-year-old female patient, reaching values seen with gastric carcinomas. Extragastric sources of CA 72-4 elevation were ruled out. The elevation slowly returned to normal levels after two courses of triple and sequential eradication therapy, causing considerable anxiety for the patient and several costly examinations...
May 2016: Zeitschrift Für Gastroenterologie
Yasir Serag Alnor Gorafi, Amin Elsadig Eltayeb, Hisashi Tsujimoto
Under the changing climate, early flowering is advantageous to escape terminal heat and drought. Previously during evaluation of 14 chromosome introgression lines (ILs), we found three ILs that flowered a month earlier than their wheat background Chinese Spring (CS). This paper describes the cause of the early flowering in the ILs and provides insight into the evolution of spring wheat from the winter wheat. We used specific molecular markers for Vrn genes to determine its allelic composition. Phenotypic evaluations carried out under field conditions and in a growth chamber...
March 2016: Breeding Science
Anna Wójcik, Mariusz Radoń, Tomasz Borowski
Four mechanisms previously proposed for dioxygen activation catalyzed by α-keto acid dependent oxygenases (α-KAO) were studied with dispersion-corrected DFT methods employing B3LYP and TPSSh functionals in combination with triple-ζ basis set (cc-pVTZ). The aim of this study was to revisit mechanisms suggested in the past decade and resolve remaining issues related to dioxygen activation. Mechanism A, which runs on the quintet potential energy surface (PES) and includes formation of an Fe(III)-superoxide radical anion complex, subsequent oxidative decarboxylation, and O-O bond cleavage, was found to be most likely...
March 3, 2016: Journal of Physical Chemistry. A
Jinyan Li, Guowei Zhang, Ximing Wang, Yanhua Duan, Xiaopeng Ji, Ting Cao, Wenyue Sun, Yaodong Qi
OBJECTIVE: To assess the feasibility of individual contrast injection protocols in triple-rule-out computed tomography examination using a dual-source Flash-chest-pain technique. METHODS: From April to August 2014, 63 patients with undifferentiated acute chest pain underwent ECG-synchronized dual-spiral chest CT angiography. 31 Patients, who all had low (<65 bpm) and stable heart rate underwent TRO CT angiography in a Flash mode, with an individual triphasic contrast protocol based on weight (350 mgI/ml, A: 0...
August 4, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Udo Hoffmann, Scott R Akers, Richard K J Brown, Kristopher W Cummings, Ricardo C Cury, S Bruce Greenberg, Vincent B Ho, Joe Y Hsu, James K Min, Kalpesh K Panchal, Arthur E Stillman, Pamela K Woodard, Jill E Jacobs
Primary imaging options in patients at low risk for coronary artery disease (CAD) who present with undifferentiated chest pain and without signs of ischemia are functional testing with exercise or pharmacologic stress-based electrocardiography, echocardiography, or myocardial perfusion imaging to exclude myocardial ischemia after rule-out of myocardial infarction and early cardiac CT because of its high negative predictive value to exclude CAD. Although possible, is not conclusive whether triple-rule-out CT (CAD, pulmonary embolism, and aortic dissection) might improve the efficiency of patient management...
December 2015: Journal of the American College of Radiology: JACR
Thomas D Glanville, Heekwon Ahn, Neslihan Akdeniz, Benjamin P Crawford, Jacek A Koziel
A passively-ventilated plastic-wrapped composting system initially developed for biosecure disposal of poultry mortalities caused by avian influenza was adapted and tested to assess its potential as an emergency disposal option for disease-related swine mortalities. Fresh air was supplied through perforated plastic tubing routed through the base of the compost pile. The combined air inlet and top vent area is ⩽∼1% of the gas exchange surface of a conventional uncovered windrow. Parameters evaluated included: (1) spatial and temporal variations in matrix moisture content (m...
February 2016: Waste Management
Vilma Ratti, Olivia Pagani
BACKGROUND: Glycogen-rich clear cell breast carcinoma is a rare histological breast cancer subtype. Its prognosis may vary depending on specific clinical and pathological characteristics such as low grade, strong positivity of estrogen receptor (ER) expression and early diagnosis. CASE PRESENTATION: We present the case of a 53-year-old woman with a bleeding 10-cm-diameter mass in the left breast. The histological examination showed a poorly differentiated tumor with malignant cells characterized by abundant clear cytoplasm...
September 2015: Case Reports in Oncology
Kelly N Sawyer, Payal Shah, Lihua Qu, Michael C Kurz, Carol L Clark, Robert A Swor
INTRODUCTION: Undifferentiated chest pain in the emergency department (ED) is a diagnostic challenge. One approach includes a dedicated chest computed tomography (CT) for pulmonary embolism or dissection followed by a cardiac stress test (TRAD). An alternative strategy is a coronary CT angiogram with concurrent chest CT (Triple Rule Out, TRO). The objective of this study was to describe the ED patient course and short-term safety for these evaluation methods. METHODS: This was a retrospective observational study of adult patients presenting to a large, community ED for acute chest pain who had non-diagnostic electrocardiograms (ECGs) and normal biomarkers...
September 2015: Western Journal of Emergency Medicine
Dimitrios G Liakos, Frank Neese
In this study the question of what is the last unbranched alkane that prefers a linear conformation over a folded one is revisited from a theoretical point of view. Geometries have been optimized carefully using the most accurate theoretical approach available to date for such systems, namely, doubly hybrid density functional theory in conjunction with larger quadruple-ζ quality basis sets. The resulting geometries deviate significantly from previously reported ones and have a significant impact on the predicted energetics...
May 12, 2015: Journal of Chemical Theory and Computation
Te-Lu Yap, Yong Chen, Wilson Wei Xin Low, Caroline Choo Phaik Ong, Shireen Anne Nah, Anette S Jacobsen, Liang Shen, Yee Low
AIM: The aim of this study was to develop a new Children's Appendicitis Score (CAS) by combining 3 inflammatory markers and a set of predictors for suspected appendicitis in children. METHODS: 374 children aged 4-16years with suspicion of appendicitis were prospectively enrolled for the derivation cohort. Demographic characteristics, clinical features, laboratory, and histology data were collected. The outcome measure was the histological presence or absence of appendicitis...
December 2015: Journal of Pediatric Surgery
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"