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noninvasive vascular imaging

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https://www.readbyqxmd.com/read/28634807/differential-diagnosis-between-benign-and-malignant-soft-tissue-tumors-utilizing-ultrasound-parameters
#1
Takeshi Morii, Tomonori Kishino, Naoko Shimamori, Mitsue Motohashi, Hiroaki Ohnishi, Keita Honya, Takayuki Aoyagi, Takashi Tajima, Shoichi Ichimura
PURPOSE: Preoperative discrimination between benign and malignant soft tissue tumors is critical for the prevention of excess application of magnetic resonance imaging and biopsy as well as unplanned resection. Although ultrasound, including power Doppler imaging, is an easy, noninvasive, and cost-effective modality for screening soft tissue tumors, few studies have investigated reliable discrimination between benign and malignant soft tissue tumors. METHODS: To establish a modality for discrimination between benign and malignant soft tissue tumors using ultrasound, we extracted the significant risk factors for malignancy based on ultrasound information from 40 malignant and 56 benign pathologically diagnosed soft tissue tumors and established a scoring system based on these risk factors...
June 20, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28614306/photoacoustic-confocal-dermoscope-with-a-waterless-coupling-and-impedance-matching-opto-sono-probe
#2
Haigang Ma, Sihua Yang, Zhongwen Cheng, Da Xing
Recently, intensive research on photoacoustic (PA) imaging has been conducted to accelerate the development of dermoscopy of the human skin. In this Letter, we first developed a PA dermoscope equipped with a waterless coupling and impedance matching opto-sono probe to achieve quantitative, high-resolution, and high-contrast imaging of the human skin. Compared with the commonly used liquid-coupled PA probes, the human-skin-adapted probe can facilitate implementation in the clinical setting. The noninvasive imaging experiments of epidermal and dermal structures in volunteers have been carried out to demonstrate the high imaging quality that can be obtained by using such an opto-sono probe for a PA dermoscope...
June 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28614137/swept-source-optical-coherence-tomography-angiography-in-rickettsial-retinitis
#3
Rim Kahloun, Bechir Jelliti, Imen Ksiaa, Hager Ben Amor, Sonia Zaouali, Marco Lupidi, Salim Ben Yahia, Moncef Khairallah
PURPOSE: To report optical coherence tomography angiography findings in a patient with rickettsial retinitis. METHODS: A 29-year-old man complaining of acute blurring vision in the right eye associated with Rickettsia conorii infection underwent a comprehensive ocular examination, fluorescein angiography, spectral-domain optical coherence tomography, and swept-source optical coherence tomography angiography. RESULTS: Funduscopy showed two large areas of retinitis in the inferior macula along the distribution of the inferotemporal artery with associated retinal hemorrhages, retinal edema, and serous retinal detachment...
June 13, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28613354/the-quantitative-measurements-of-vascular-density-and-flow-areas-of-macula-using-optical-coherence-tomography-angiography-in-normal-volunteers
#4
Fariba Ghassemi, Kaveh Fadakar, Fatemeh Bazvand, Reza Mirshahi, Masoumeh Mohebbi, Siamak Sabour
BACKGROUND AND OBJECTIVE: The quantification of the density of macular vascular networks and blood flow areas in the foveal and parafoveal area in healthy subjects using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Cross-sectional, prospective study in an institutional setting at the Retina Services of Farabi Eye Hospital. One hundred twelve normal volunteers with no known ocular or systemic disease were included, including patient numbers (one or both eyes), selection procedures, inclusion/exclusion criteria, randomization procedure, and masking...
June 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28613216/polypoidal-choroidal-vasculopathy-upon-optical-coherence-tomographic-angiography
#5
Szy Yann Chan, Qian Wang, Ya Xing Wang, Xue Hui Shi, Jost B Jonas, Wen Bin Wei
PURPOSE: To study polypoidal lesions and branching choroidal vascular networks in eyes with polypoidal choroidal vasculopathy by optical coherence tomography (OCT)-based angiography (OCTA). METHODS: In the observational cross-sectional study, patients with polypoidal choroidal vasculopathy, as diagnosed by indocyanine green angiography, underwent OCTA. RESULTS: Thirty-two eyes of 31 patients with an age of 61.1 ± 7.6 years were included. Branching choroidal vascular networks were detected by indocyanine green angiography and OCTA in 25 of 32 (78 ± 73%) and in 30 of 32 (94 ± 4%) eyes, respectively, with a marginally significant difference (P = 0...
May 22, 2017: Retina
https://www.readbyqxmd.com/read/28605001/determination-of-structural-femoral-head-allograft-viability-and-integrity-with-a-novel-diagnostic-tool-spect-ct-a-preliminary-study
#6
Kasım Kilicarslan, Nadir Yalcin, Vedat Bicici, Elif Ozdemir, Izzet Bingol, Seyda Turkolmez
OBJECTIVE: To evaluate the viability and integrity of fresh frozen bulk femoral head allografts obtained from the institutional bone bank that were used to reconstruct severe acetabular defects and to validate the SPECT/CT method which gives both anatomical and functional data for this purpose. METHODS: We retrospectively reviewed 9 patients (6 female, 3 male; mean age 63.6 years). Preoperative and postoperative leg lengths, existence of the Trendelenburg sign, range of motion of the hip, visual analogue score (VAS), Harris Hip Score (HHS) and any complication were assesed at each follow-up...
June 2, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28596917/assessment-of-vascular-change-using-swept-source-optical-coherence-tomography-angiography-a-new-theory-explains-central-visual-loss-in-behcet-s-disease
#7
Thanapong Somkijrungroj, Sritatath Vongkulsiri, Wijak Kongwattananon, Peranut Chotcomwongse, Sasivarin Luangpitakchumpol, Korrawan Jaisuekul
OBJECTIVE: To evaluate retinal vascular structural change in ocular Behcet's using optical coherence tomography angiography (OCTA) and fluorescein angiography (FA). METHODS: An analytic cross-sectional study of 37 eyes of 21 Behcet's uveitic patients was performed. Foveal retinal thickness (FRT), perifoveal hypoperfusion areas in superficial capillary plexus (SCP), and deep capillary plexus (DCP) were measured with swept-source optical coherence tomography and OCTA...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28593557/assessment-of-myocardial-blood-flow-and-coronary-flow-reserve-with-positron-emission-tomography-in-ischemic-heart-disease-current-state-and-future-directions
#8
REVIEW
Firas Al Badarin, Ahmed Aljizeeri, Fatimah Almasoudi, Mouaz H Al-Mallah
Positron emission tomography (PET) is a versatile imaging technology that allows assessment of myocardial perfusion, both at a spatially relative scale and also in absolute terms, thereby enabling noninvasive evaluation of myocardial blood flow (MBF) and coronary flow reserve (CFR). Assessment of MBF using FDA-approved PET isotopes, such as (82)Rb and (13)N-ammonia, has been well validated, and several software packages are currently available, thereby allowing for MBF evaluation to be incorporated into routine workflow in contemporary nuclear laboratories...
June 7, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28590938/combined-passive-acoustic-mapping-and-magnetic-resonance-thermometry-for-monitoring-phase-shift-nanoemulsion-enhanced-focused-ultrasound-therapy
#9
Calum Crake, F Can Meral, Mark Burgess, Iason Papademetriou, Nathan McDannold, Tyrone Porter
Focused ultrasound (FUS) has the potential to enable precise, image-guided noninvasive surgery for the treatment of cancer in which tumors are identified and destroyed in a single integrated procedure. However, success of the method in highly vascular organs has been limited due to heat losses to perfusion, requiring development of techniques to locally enhance energy absorption and heating. In addition, FUS procedures are conventionally monitored using MRI, which provides excellent anatomical images and can map temperature, but is not capable of capturing the full gamut of available data such as the acoustic emissions generated during this inherently acoustically-driven procedure...
June 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28590796/noninvasive-therapy-for-osteoid-osteoma-a-prospective-developmental-study-with-mr-imaging-guided-high-intensity-focused-ultrasound
#10
Alessandro Napoli, Alberto Bazzocchi, Roberto Scipione, Michele Anzidei, Luca Saba, Pejman Ghanouni, Denis A Cozzi, Carlo Catalano
Purpose To demonstrate that magnetic resonance (MR) imaging-guided high-intensity focused ultrasound (HIFU) is a safe, effective, and durable treatment option for the management of osteoid osteoma in children and young adults. Materials and Methods This prospective study was institutional review board approved and is registered with clinicaltrials.gov (identification number NCT02302651). Written informed consent was obtained from patients or their parents. Patients who had both clinical and radiologic findings that were diagnostic for nonvertebral osteoid osteoma and no contraindications to MR imaging-guided HIFU were enrolled between June 2010 and June 2013...
June 7, 2017: Radiology
https://www.readbyqxmd.com/read/28582276/biomarkers-of-neovascular-activity-in-age-related-macular-degeneration-using-oct-angiography
#11
Mayss Al-Sheikh, Nicholas A Iafe, Nopasak Phasukkijwatana, SriniVas R Sadda, David Sarraf
PURPOSE: To study the qualitative and quantitative features of choroidal neovascular (NV) membranes in age-related macular degeneration using optical coherence tomography angiography in patients with active and quiescent NV lesions before and after treatment with anti-vascular endothelial growth factor. METHODS: Macular optical coherence tomography angiography images were obtained using RTVue XR Avanti with AngioVue. Morphologic features and quantitative measurements of the NV lesion were analyzed using en face projection images...
May 2, 2017: Retina
https://www.readbyqxmd.com/read/28558368/molecular-imaging-of-inducible-vegf-expression-and-tumor-progression-in-a-breast-cancer-model
#12
Lu Liang, Zhiwei Yue, Wei Du, Yang Li, Hongyan Tao, Di Wang, Ran Wang, Ziwei Huang, Ningning He, Xiaoyan Xie, Zhongchao Han, Na Liu, Zongjin Li
BACKGROUND: Tumor derived vascular endothelial growth factor (VEGF) can stimulate proliferation and migration of endothelial cells and recruit endothelial progenitor cells into tumors for vascular formation via a paracrine manner. Now increasing evidence suggests that VEGF also serves as an autocrine factor promoting cell survival and tumor angiogenesis. Real time visualization of VEGF activity in the early stages of tumor formation using molecular imaging will provide unprecedented insight into the biological processes of cancer...
2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28552136/epidemiology-clinical-presentation-diagnostic-evaluation-and-prognosis-of-spinal-arteriovenous-malformations
#13
Alp Ozpinar, Gregory M Weiner, Andrew F Ducruet
Spinal arteriovenous malformations (sAVM) are rare vascular pathologies whose natural history remains incompletely understood. Advances in diagnostic imaging, coupled with the evolution of endovascular and microsurgical techniques have led to the description of a number of classification schemes for these lesions. An updated method has changed AVM classification from five categories of lesion based on source and location of feeder vessels to three categories based on pathophysiology. These categories include extradural arteriovenous fistulae (AVFs), intradural AVFs, extradural-intradural AVFs, intramedullary AVMs, and conus medullaris AVM each with individual subclassifications...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28548465/assessment-of-infantile-hemangiomas-using-a-handheld-wireless-diffuse-optical-spectroscopic-device
#14
Christopher J Fong, Maria C Garzon, Jennifer W Hoi, Hyun K Kim, Christine T Lauren, Kimberly Morel, Lauren Geller, Nina Antonov, Nicole Weitz, June Wu, Andreas H Hielscher
BACKGROUND/OBJECTIVES: Infantile hemangiomas (IHs) are vascular tumors with the potential for significant morbidity. There is a lack of validated objective tools to assess IH severity and response to treatment. Diffuse optical spectroscopy (DOS), a noninvasive, nonionizing imaging modality, can measure total hemoglobin concentration and hemoglobin oxygen saturation in tissue to assess IH vascularity and response to treatment. Our objective was to evaluate the utility of a wireless, handheld DOS system to assess IH characteristics at selected points during their clinical course...
May 26, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28545358/molecular-imaging-of-tumor-angiogenesis-and-therapeutic-effects-with-dual-bioluminescence
#15
Ran Wang, Kaiyue Zhang, Hongyan Tao, Wei Du, Di Wang, Ziwei Huang, Manqian Zhou, Yang Xu, Yuebing Wang, Na Liu, Hui Wang, Zongjin Li
BACKGROUND: Angiogenesis is critical for the growth of tumor by supplying nutrients and oxygen that exacerbates the metastasis and progression of cancer. Noninvasive imaging of angiogenesis during the tumor therapeutic processes may provide novel opportunities for image-guided tumor management. OBJECTIVE: Here, we want to develop a mouse animal model for assessing cancer progression and angiogenesis in the same individuals by molecular imaging. METHODS: Breast cancer model was developed with mouse breast cancer cell line 4T1 carrying a reporter system encoding a triple fusion (TF) reporter gene consisting of renilla luciferase (Rluc), red fluorescent protein (RFP) and herpes simplex virus truncated thymidine kinase (HSV-ttk) in transgenic mice, which expressed firefly luciferase (Fluc) under the promoter of vascular endothelial growth factor receptor 2 (Vegfr2-luc)...
May 23, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28538567/hyperspectral-imaging-provides-early-prediction-of-random-axial-flap-necrosis-in-a-preclinical-model
#16
Michael S Chin, Ava G Chappell, Giorgio Giatsidis, Dylan J Perry, Jorge Lujan-Hernandez, Anthony Haddad, Hajime Matsumine, Dennis P Orgill, Janice F Lalikos
BACKGROUND: Necrosis remains a significant complication in cutaneous flap procedures. Monitoring, and ideally prediction, of vascular compromise in the early postoperative period may allow surgeons to limit the impact of complications by prompt intervention. Hyperspectral imaging could be a reliable, effective, and noninvasive method for predicting flap survival postoperatively. In this preclinical study, the authors demonstrate that hyperspectral imaging is able to correlate early skin perfusion changes and ultimate flap survival in a preclinical model...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28525681/unveiling-idiopathic-macular-telangiectasia-clinical-applications-of-optical-coherence-tomography-angiography
#17
Marco A Gonzalez, Diana Shechtman, Jay M Haynie, Leo Semes
PURPOSE: Idiopathic macular telangiectasia type 2 (IMT2) is a bilateral acquired maculopathy, with a spectrum of clinical presentations associated with inner retinal telangiectatic vascular anomalies. Cases often are underdiagnosed or misdiagnosed. Current diagnostic modalities such as spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) are valuable to the understanding of the clinicopathology. More recently, optical coherence tomography angiography (OCTA), as an emerging noninvasive technology, has been shown to be particularly useful in the assessment and management of IMT2...
May 19, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28521772/feasibility-and-relevance-of-compound-strain-imaging-in-non-stenotic-arteries-comparison-between-individuals-with-cardiovascular-diseases-and-healthy-controls
#18
Martijn F H Maessen, Thijs M H Eijsvogels, Ayla Grotens, Maria T E Hopman, Dick H J Thijssen, Hendrik H G Hansen
BACKGROUND: Compound strain imaging is a novel method to noninvasively evaluate arterial wall deformation which has recently shown to enable differentiation between fibrous and (fibro-)atheromatous plaques in patients with severe stenosis. We tested the hypothesis that compound strain imaging is feasible in non-stenotic arteries and provides incremental discriminative power to traditional measures of vascular health (i.e., distensibility coefficient (DC), central pulse wave velocity [cPWV], and intima-media thickness [IMT]) for differentiating between participants with and without a history of cardiovascular diseases (CVD)...
May 18, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28520896/laser-assisted-indocyanine-green-dye-angiography-for-postoperative-fistulas-after-salvage-laryngectomy
#19
Erin J Partington, Lindsay S Moore, Russel Kahmke, Jason M Warram, William Carroll, Eben L Rosenthal, Benjamin J Greene
Importance: Pharyngocutaneous fistula formation is an unfortunate complication after salvage laryngectomy for head and neck cancer that is difficult to anticipate and related to a variety of factors, including the viability of native pharyngeal mucosa. Objective: To examine whether noninvasive angiography with indocyanine green (ICG) dye can be used to evaluate native pharyngeal vascularity to anticipate pharyngocutaneous fistula development. Design, Setting, and Participants: This cohort study included 37 patients enrolled from June 1, 2013, to June 1, 2016, and follow-up was for at least 1 month postoperatively...
May 18, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28513892/assessment-of-nonarteritic-anterior-ischemic-optic-neuropathy-with-intravoxel-incoherent-motion-diffusion-weighted-imaging-using-readout-segmented-echo-planar-imaging-parallel-imaging-and-2d-navigator-based-reacquisition
#20
Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tan, Wenlin Tang
PURPOSE: To determine the feasibility of intravoxel incoherent motion (IVIM) for characterizing perfusion properties and its potential diagnostic utility for nonarteritic anterior ischemic optic neuropathy (NAION). IVIM diffusion-weighted imaging is a promising technique that can measure perfusion and diffusion characteristics simultaneously in a noninvasive manner. MATERIALS AND METHODS: Orbital IVIM in a 3.0T scanner was performed on 33 patients with NAION and 15 controls using readout-segmented echo-planar imaging, parallel imaging, and 2D navigator-based reacquisition (RESOLVE-IVIM)...
May 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
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