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mohammad Ali javadi

Hossein Mohammad Rabie, Parviz Malekifar, Mohammad Ali Javadi, Danial Roshandel, Hamed Esfandiari
PURPOSE: To review our experience with crystalline lens extraction and iris claw Artisan IOL implantation in patients with lens subluxation secondary to Marfan syndrome. METHODS: A retrospective analysis of 12 eyes of 9 patients with lens subluxation due to Marfan syndrome who underwent crystalline lens removal and Artisan IOL (Ophtec, Groningen, Netherlands) implantation. A questionnaire of pre- and post-operative data, including demographics, pre- and postoperative comorbidities and complications was completed...
October 5, 2016: International Ophthalmology
Sajjad Javadi, Reza Yousefi, Saman Hosseinkhani, Ali-Mohammad Tamaddon, Vladimir N Uversky
The high level of dehydroascorbic acid (DHA) in the lenticular tissue is an important risk factor for the development of age-related cataracts. In this study, the effects of DHA on structure and function of lens crystallins were studied in the presence of carnosine using gel mobility shift assay, different spectroscopic techniques, and lens culture analysis. The DHA-induced unfolding and aggregation of lens proteins were largely prevented by this endogenous dipeptide. The ability of carnosine to preserve native protein structure upon exposure to DHA suggests the essential role of this dipeptide in prevention of the senile cataract development...
July 29, 2016: Journal of Biomolecular Structure & Dynamics
Sepehr Feizi, Mozhgan Rezaei Kanavi, Davood Kharaghani, Sahar Balagholi, Masoumeh Meskinfam, Mohammad Ali Javadi
PURPOSE: To characterize the walls of big bubbles formed during deep anterior lamellar keratoplasty (DALK) using the corrosion casting technique. METHODS: Fresh corneoscleral buttons with normal transparency and without any known eye diseases (n = 11) were obtained from 11 human donors. A 20-gauge needle was used to inject a solution of 20 % polyvinyl alcohol (PVA) immediately beneath the corneal endothelium to form big bubbles in eight corneoscleral buttons...
July 19, 2016: Japanese Journal of Ophthalmology
Hossein Mohammad-Rabei, Elham Mohammad-Rabei, Goldis Espandar, Mohammad Ali Javadi, Mohammad Reza Jafarinasab, Seyed Javad Hashemian, Sepehr Feizi
PURPOSE: To compare the safety and efficacy of three methods for correcting pre-existing astigmatism during phacoemulsification. METHODS: This prospective, comparative, non-randomized study was conducted from March 2010 to January 2011, and included patients with keratometric astigmatism ≥1.25 D undergoing cataract surgery. Astigmatism was corrected using the following approaches: limbal relaxing incisions (LRI) on the steep meridian, extension and suturing of the phaco incision created at the steep meridian (extended-on-axis incision, EOAI), and toric intraocular lens (tIOL) implantation...
April 2016: Journal of Ophthalmic & Vision Research
Mozhgan Rezaei Kanavi, Mohammad Ali Javadi, Tahmineh Motevasseli, Tahereh Chamani, Mahnoush Rezaei Kanavi, Bahareh Kheiri, Sare Safi
PURPOSE: To report changing trends in indications and techniques of corneal transplantation in Iran. METHODS: We reviewed eye bank records of 47,129 patients who had undergone corneal transplantation between 2006 and 2013 at different eye centers throughout Iran. RESULTS: The most common indication for corneal transplantation was keratoconus (KCN, n = 21,350 eyes, 45.3%), followed by bullous keratopathy (BK, n = 8,566 eyes, 18.2%), corneal opacity and scar (COS, n = 7,158 eyes, 15...
April 2016: Journal of Ophthalmic & Vision Research
Mohammad Ali Javadi, Hossein Mohammad-Rabei, Sepehr Feizi, Seyed-Hashem Daryabari
PURPOSE: To compare the visual outcomes of deep anterior lamellar keratoplasty (DALK) for keratoconus with and without successful big-bubble formation. METHODS: In this retrospective comparative study, a total of 289 consecutive eyes from 257 patients underwent DALK using the big-bubble technique. In cases where the big bubble could not be accomplished, manual stromal dissection down to Descemeton membrane (DM) was performed using a crescent knife. Visual acuity and refractive outcomes were compared between the bare DM group (Group 1) and manual dissection group (Group 2)...
January 2016: Journal of Ophthalmic & Vision Research
Muhammad Junaid, Aung Khine Linn, Mohammad Bagher Javadi, Sarbast Al-Gubare, Niaz Ali, Gerd Katzenmeier
Helicobacter pylori is associated with severe and chronic diseases of the stomach and duodenum such as peptic ulcer, non-cardial adenocarcinoma and gastric lymphoma, making Helicobacter pylori the only bacterial pathogen which is known to cause cancer. The worldwide rate of incidence for these diseases is extremely high and it is estimated that about half of the world's population is infected with H. pylori. Among the bacterial virulence factors is the vacuolating cytotoxin A (VacA), which represents an important determinant of pathogenicity...
August 2016: Toxicon: Official Journal of the International Society on Toxinology
Mansoor Shahriari, Sayed Bagher Hosseini, Roshanak Aliakbar-Navahi, Mohammad Ali Javadi, Yalda Abrishami
To report two cases of bilateral conjunctival granuloma with histopathological features of the Splendore-Hoeppli phenomenon and review of the literature. Two female patients, one with a history of pulmonary eosinophilic infiltration and another with a history of vernal keratoconjunctivitis, presented with bilateral cream to yellow colored nodules in the superior bulbar conjunctiva. Histopathologic examination revealed characteristic features of the Splendore-Hoeppli phenomenon manifesting as zones of amorphous eosinophilic material surrounded by aggregations of epithelioid histiocytes, giant cells, eosinophils and lymphoplasmacytic infiltrates...
October 2015: Journal of Ophthalmic & Vision Research
Zhaleh Rajavi, Mohammad Ali Javadi, Narsis Daftarian, Sare Safi, Farhad Nejat, Armin Shirvani, Hamid Ahmadieh, Saeid Shahraz, Hossein Ziaei, Hamidreza Moein, Behzad Fallahi Motlagh, Sepehr Feizi, Alireza Foroutan, Hassan Hashemi, Seyed Javad Hashemian, Mahmoud Jabbarvand, Mohammad Reza Jafarinasab, Farid Karimian, Hossein Mohammad-Rabei, Mehrdad Mohammadpour, Nader Nassiri, Mahmoodreza Panahi-Bazaz, Mohammad Reza Rohani, Mohammad Reza Sedaghat, Kourosh Sheibani
PURPOSE: To customize clinical practice guidelines (CPGs) for cataract management in the Iranian population. METHODS: First, four CPGs (American Academy of Ophthalmology 2006 and 2011, Royal College of Ophthalmologists 2010, and Canadian Ophthalmological Society 2008) were selected from a number of available CPGs in the literature for cataract management. All recommendations of these guidelines, together with their references, were studied. Each recommendation was summarized in 4 tables...
October 2015: Journal of Ophthalmic & Vision Research
Sepehr Feizi, Mohammad Ali Javadi, Hassan Ghasemi, Fatemeh Javadi
PURPOSE: To evaluate the effect of donor and eye bank characteristics on graft rating and clinical outcomes after penetrating keratoplasty (PK) for keratoconus. METHODS: This retrospective interventional case series included 252 keratoconic eyes which underwent PK. Donor data included age and sex, cause of death, death-to-preservation time, preservation-to-surgery time, epithelial and stromal status, endothelial cell density (ECD) and morphology, and graft rating...
October 2015: Journal of Ophthalmic & Vision Research
Sepehr Feizi, Seyed-Hashem Daryabari, Danial Najdi, Mohammad Ali Javadi, Farid Karimian
PURPOSE: To compare 2 sites of air injection to achieve Descemet membrane (DM) detachment in big-bubble deep anterior lamellar keratoplasty (DALK). METHODS: In this prospective, randomized study, 48 eyes of 48 keratoconus-affected patients who underwent DALK by cornea fellows were enrolled. Each patient was randomly assigned into one of 2 groups. After trephination to approximately 80% of the corneal thickness, a 27-G needle was inserted into the stroma from the trephination site...
June 10, 2016: European Journal of Ophthalmology
Maryam Eslami, Gholamreza Javadi, Nasser Agdami, Mohammad Ali Shokrgozar
OBJECTIVE: The incidence of heart valve disease is increasing worldwide and the number of heart valve replacements is expected to increase in the future. By mimicking the main tissue structures and properties of heart valve, tissue engineering offers new options for the replacements. Applying an appropriate scaffold in fabricating tissue-engineered heart valves (TEHVs) is of importance since it affects the secretion of the main extracellular matrix (ECM) components, collagen 1 and elastin, which are crucial in providing the proper mechanical properties of TEHVs...
2015: Cell Journal
Sepehr Feizi, Mohammad Ali Javadi, Seyed-Hashem Daryabari
PURPOSE: To investigate recipient and operative factors that can influence the rate of achieving a bare Descemet's membrane (DM) during deep anterior lamellar keratoplasty (DALK) for keratoconus. MATERIALS: In this retrospective comparative study, a total of 290 (153 right) consecutive eyes from 257 (179 male) keratoconus-affected patients who underwent DALK with the big-bubble technique were enrolled. Univariate analyses and multiple logistic regressions were used to investigate factors including patient age and sex, family history of keratoconus, history of contact lens wear or vernal keratoconjunctivitis, the presence of Vogt's striae or superficial stromal opacities, keratometric readings, corneal diameter, central and peripheral corneal thickness, anterior chamber depth, vitreous length, and trephination size, which could predict achievement of a bare DM...
May 2016: British Journal of Ophthalmology
Sepehr Feizi, Mohammad Ali Javadi
PURPOSE: To determine the factors that predict refraction, mean keratometry, and keratometric astigmatism after deep anterior lamellar keratoplasty (DALK) in keratoconus. DESIGN: Consecutive interventional case series. METHODS: This study enrolled 194 consecutive eyes of 181 patients with keratoconus who underwent DALK using the big-bubble technique. Indications for surgery included contact lens intolerance or poor corrected visual acuity...
October 2015: American Journal of Ophthalmology
Amir Ali Hamidieh, Mona Sherafatmand, Ava Mansouri, Molouk Hadjibabaie, Asieh Ashouri, Zahra Jahangard-Rafsanjani, Kheirollah Gholami, Mohammad Reza Javadi, Ardeshir Ghavamzadeh, Mania Radfar
Fanconi anemia is a rare inherited aplastic anemia, which is cured only by hematopoietic stem-cell transplantation (HSCT). One of the most debilitating complications of high-dose chemotherapy regimen before HSCT is oral mucositis (OM), which occurs frequently in this population. Vitamin D has identified immunoregulatory, anti-inflammatory, and antioxidant role. This study was designed to examine the efficacy of vitamin D in the prevention of OM in patients with Fanconi anemia undergoing allogenic HSCT. Twenty-eight patients were enrolled in the study...
July 8, 2015: American Journal of Therapeutics
Marzieh Katibeh, Sara Hosseini, Mehdi Yaseri, Mohammad Naiem Aminifar, Alireza Mahdavi, Mohammad Reza Jafarinasab, Mohammad Ali Javadi
PURPOSE: To determine the prevalence of trachoma and risk factors associated with the disease in rural areas of the Sistan-va-Baluchestan province in Iran from 2012-2013. Population-based prevalence data for trachoma is lacking in this region. METHODS: In this population-based cross-sectional study, 80 clusters were selected using a systematic and probability proportional to size method. All participants underwent clinical eye examinations according to the World Health Organization simplified trachoma grading system...
2015: Ophthalmic Epidemiology
Sepehr Feizi, Mohammad Ali Javadi
PURPOSE: To compare 2 sites of air injection to prepare donor lenticules for Descemet membrane (DM) endothelial keratoplasty. METHODS: Fifty-one human corneoscleral buttons from donors aged 4 to 57 years were used. Corneoscleral buttons were placed endothelial side up and a 27-G needle was inserted just outside Schwalbe line and advanced immediately beneath the endothelium. Air was injected centrally inside the 8-mm zone (group 1) or peripherally approximately 1 mm in front of the limbus (group 2)...
January 2016: European Journal of Ophthalmology
Siamak Delfazayebaher, Sepehr Feizi, Mohammad Ali Javadi, Alireza Baradaran-Rafii, Mohammad Mehdi Sadoughi, Amir Faramarzi
PURPOSE: To describe a sign that can confirm the correct position of donor lenticules during Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: In this clinical and laboratory study, DSAEK was performed in 3 eyes with a diagnosis of pseudophakic bullous keratopathy. Additionally, 2 whole globes and 2 precut corneoscleral buttons were procured for the purpose of the laboratory part of the study. After removal of recipient Descemet membrane, the donor graft was inserted into the anterior chamber, unfolded, and attached to the posterior corneal stroma with an air bubble...
August 2015: Cornea
Reza Najafipour, Abolfazl Heidari, Safar Ali Alizadeh, Hannaneh Ghafelebashi, Zahra Rashvand, Amir Javadi, Mohammad Moradi, Hosein Afshar
BACKGROUND: Caveolin is a multifunctional and scaffolding membrane protein, which involves cholesterol trafficking to plasma lipid microdomain. It organizes and targets synaptic parts of the neurotransmitter and neurotrophic receptor signaling pathways. Caveolins are encoded by CAV-1, 2 and 3 genes. Disruption of the CAV1 would likely ruin the neuronal signaling, which leads to symptoms of schizophrenia in predisposed individuals. OBJECTIVES: The upper area of CAV-1 gene is highly conserved and can have a regulatory role in neurodegenerative diseases...
December 2014: Iranian Red Crescent Medical Journal
Mohammad-Ali Javadi, Sepehr Feizi
PURPOSE: To report a keratoconic eye that developed severe sterile keratitis and corneal scar after collagen crosslinking necessitating corneal transplantation. CASE REPORT: A 26-year-old man with progressive keratoconus underwent collagen crosslinking and presented with severe keratitis 72 hours after the procedure. The initial impression was infectious corneal ulcer and a fortified antibiotic regimen was administered. However, the clinical course and confocal microscopy results prompted a diagnosis of sterile keratitis...
October 2014: Journal of Ophthalmic & Vision Research
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