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https://www.readbyqxmd.com/read/28319822/comparison-of-intravenous-versus-topical-tranexamic-acid-in-primary-total-hip-and-knee-arthroplasty-an-updated-meta-analysis
#1
REVIEW
Jinwei Xie, Qinsheng Hu, Qiang Huang, Jun Ma, Yiting Lei, Fuxing Pei
BACKGROUND: The appropriate route for administering tranexamic acid in primary total hip (THA) and knee arthroplasty (TKA) remains controversial. The purpose of this meta-analysis was to compare the efficacy and safety of topical or intravenous tranexamic acid. METHODS: PubMed, EMBASE, and the Cochrane Library databases were systematically searched for randomized controlled trials (RCTs) comparing topical and intravenous tranexamic acid following primary THA or TKA...
March 10, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28319549/therapeutic-plasma-transfusion-in-bleeding-patients-a-systematic-review
#2
Jerrold H Levy, Oliver Grottke, Dietmar Fries, Sibylle Kozek-Langenecker
Plasma products, including fresh frozen plasma, are administered extensively in a variety of settings from massive transfusion to vitamin K antagonist reversal. Despite the widespread use of plasma as a hemostatic agent in bleeding patients, its effect in comparison with other available choices of hemostatic therapies is unclear. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PubMed Central, and databases of ongoing trials for randomized controlled trials that assessed the efficacy and/or safety of therapeutic plasma as an intervention to treat bleeding patients compared with other interventions or placebo...
April 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28319308/concepts-models-and-measurement-of-continuity-of-care-in-mental-health-services-a-systematic-appraisal-of-the-literature
#3
REVIEW
Nick Weaver, Michael Coffey, Jeanette Hewitt
INTRODUCTION: The increased complexity of community mental health services, and associated fragmentation of traditional dividing lines between services, has underscored the centrality of care continuity and coordination in modern mental healthcare. However, clarification of the key features of the care continuity concept has proved difficult and a consensus has not been reached. AIM/QUESTION: This review draws together and critically examines latest evidence concerning concepts, models and scales based on a multi-dimensional understanding of care continuity...
March 20, 2017: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/28319277/the-systematic-review-and-meta-analysis-of-free-flap-safety-in-the-elderly-patients
#4
Galip Gencay Üstün, Ali Emre Aksu, Hakan Uzun, Ozan Bitik
BACKGROUND: Prolonged mean life expectancy gives rise to a more populated and older patient group. With increasing number of cases during the past decades, older patients are regarded as candidates for microsurgical interventions. Whether advanced patient age is an independent risk factor for microsurgical reconstruction is still an ongoing matter of debate. METHODS: The Cochrane Central Register of Controlled Trials, PubMed, MEDLINE, CINAHL and EMBASE databases were screened for combination of the key words "elderly", "geriatric", "advanced age", "free flap", "microsurgery", free tissue transfer" by using time limits between 1989 and 2015...
March 20, 2017: Microsurgery
https://www.readbyqxmd.com/read/28319195/serum-uric-acid-levels-in-patients-with-parkinson-s-disease-a-meta-analysis
#5
Min Wen, Bo Zhou, Yun-Hua Chen, Zhao-Lei Ma, Yun Gou, Chun-Lin Zhang, Wen-Feng Yu, Ling Jiao
BACKGROUND: Lower serum uric acid (UA) levels have been reported as a risk factor in Parkinson's disease (PD). However, the results have been inconsistent so far. OBJECTIVES: The aim of the present study was to clarify the potential relationship of uric acid with PD. METHODS: Comprehensive electronic search in pubmed, web of science, and the Cochrane Library database to find original articles about the association between PD and serum uric acid levels published before Dec 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28318958/the-association-between-carotid-artery-atherosclerosis-and-silent-brain-infarction-a-systematic-review-and-meta-analysis
#6
Caitlin Finn, Ashley E Giambrone, Gino Gialdini, Diana Delgado, Hediyeh Baradaran, Hooman Kamel, Ajay Gupta
BACKGROUND: Carotid atherosclerosis is responsible for ~20% of ischemic strokes, but it is unclear whether carotid disease is associated with the presence of downstream silent brain infarction (SBI). We performed a systematic review and meta-analysis to study the relationship between SBI and 2 separate manifestations of carotid atherosclerosis, carotid intima-media thickening (IMT) and luminal stenosis. METHODS: Ovid MEDLINE, Ovid Embase, and the Cochrane Library Database were searched with an additional search of references and citing articles of target studies...
March 15, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28318686/probiotic-supplementation-for-management-of-cardiovascular-risk-factors-in-adults-with-type-ii-diabetes-a-systematic-review-and-meta-analysis
#7
Fatemeh Hendijani, Vajihe Akbari
BACKGROUND & AIMS: The effectiveness of probiotics in control of hypertension and dyslipidemia in diabetic patients remains unclear. Therefore, we systematically reviewed relevant data to elucidate the effects of probiotics on blood pressure and lipid profile of type 2 diabetic patients. METHODS: We searched PubMed, ISI Web of Knowledge, Scopus, The Cochrane Library, ClinicalTrials.gov, ProQuest Dissertations and Theses databases until May 2016. The primary outcomes were systolic blood pressure (SBP) and diastolic blood pressure (DBP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG)...
February 24, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28318599/perinatal-risk-factors-for-infantile-hypertrophic-pyloric-stenosis-a-meta-analysis
#8
REVIEW
Jianghu Zhu, Tingting Zhu, Zhenlang Lin, Yi Qu, Dezhi Mu
BACKGROUND: Infantile hypertrophic pyloric stenosis (IHPS) is the most common surgical cause of nonbilious vomiting in infancy. The etiology of IHPS is not completely understood. Hence, we performed a meta-analysis to investigate the association between perinatal factors and IHPS onset. METHODS: The MEDLINE, EMBASE, PubMed and Cochrane Library databases were searched for studies published in English before December 2016. The combined odd ratios (ORs) and 95% confidence intervals (CIs) were calculated using random-effects models...
March 15, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28318159/-meta-analysis-of-the-condylar-position-changes-produced-by-functional-appliances-in-class-%C3%A2-malocclusion
#9
Huang Xinqi, Cen Xiao, Liu Jun
OBJECTIVE: This study aimed to analyze the condylar position changes produced by functional appliances in class Ⅱ malocclusion by systematic review. METHODS: Electronic search was conducted using Chinese Biomedical Literature Database, China National Knowledge Infrastructure, VIP Database for Chinese Technical Periodicals, Medline, Embase, Pubmed, and Cochrane Central Register of Controlled Trials. Studies on condylar position changes produced by functional appliances in class Ⅱ malocclusion were included...
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28318052/systematic-review-benefits-and-harms-of-transarterial-embolisation-for-treating-hepatocellular-adenoma
#10
REVIEW
C Zhao, S-L Pei, A Cucchetti, T-J Tong, Y-L Ma, J-H Zhong, L-Q Li
BACKGROUND: Transarterial embolisation (TAE) is a standard treatment for bleeding hepatocellular adenoma (HCA) and, occasionally, symptomatic HCA involving large tumours. Whether TAE is similarly safe and effective as an elective treatment for bleeding and nonbleeding HCA remains unclear. AIM: To investigate the benefits and harms of TAE for bleeding and nonbleeding HCA. METHODS: PubMed, Scopus, Embase and Cochrane Library databases were systematically searched for studies that examined post-TAE tumour reduction in patients with bleeding or nonbleeding HCA and that were published between January 2000 and January 2017...
March 20, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28318009/the-efficacy-of-interventions-to-increase-physical-activity-participation-of-children-with-cerebral-palsy-a-systematic-review-and-meta-analysis
#11
REVIEW
Sarah Reedman, Roslyn N Boyd, Leanne Sakzewski
AIM: To determine efficacy of therapy and behaviour change interventions to increase the level of participation in leisure-time physical activities (LTPAs) and habitual physical activity in children and young people with cerebral palsy. METHOD: Five databases were systematically searched. Included studies were randomized or comparison designs. Methodological quality was assessed with a modified Downs and Black Scale. Quantitative analysis was performed using RevMan 5...
March 20, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28318008/meta-analysis-of-prophylactic-abdominal-drainage-in-pancreatic-surgery
#12
REVIEW
F J Hüttner, P Probst, P Knebel, O Strobel, T Hackert, A Ulrich, M W Büchler, M K Diener
BACKGROUND: Intra-abdominal drains are frequently used after pancreatic surgery whereas their benefit in other gastrointestinal operations has been questioned. The objective of this meta-analysis was to compare abdominal drainage with no drainage after pancreatic surgery. METHODS: PubMed, the Cochrane Library and Web of Science electronic databases were searched systematically to identify RCTs comparing abdominal drainage with no drainage after pancreatic surgery...
March 20, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28317584/dealing-with-microscopic-peritoneal-metastases-of-epithelial-ovarian-cancer-a-surgical-challenge
#13
REVIEW
Henri Azaïs, Juan Pablo Estevez, Périne Foucher, Yohan Kerbage, Serge Mordon, Pierre Collinet
Understanding biology and progression mechanisms of peritoneal metastases of epithelial ovarian cancer (EOC) is a cornerstone in the knowledge and the comprehensive management of the disease. Despite clinical remission after the association of complete cytoreductive surgery and platinum-based chemotherapy, peritoneal recurrence still occurs in 60% of patients. Eligible studies, published from 1980 to June 2016, were retrieved through ClinicalTrials.gov, MEDLINE, Cochrane databases and bibliography searches...
March 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28317389/prp-for-degenerative-cartilage-disease
#14
Lior Laver, Niv Marom, Lad Dnyanesh, Omer Mei-Dan, João Espregueira-Mendes, Alberto Gobbi
OBJECTIVE: To explore the utilization of platelet-rich plasma (PRP) for degenerative cartilage processes and evaluate whether there is sufficient evidence to better define its potential effects. DESIGN: Systematic literature reviews were conducted in PubMed/MEDLINE and Cochrane electronic databases till May 2015, using the keywords "platelet-rich plasma OR PRP OR autologous conditioned plasma OR ACP AND cartilage OR chondrocyte OR chondrogenesis OR osteoarthritis (OA) OR arthritis...
September 1, 2016: Cartilage
https://www.readbyqxmd.com/read/28316312/partial-splenic-artery-embolization-to-treat-hypersplenism-secondary-to-hepatic-cirrhosis-a-meta-analysis
#15
Yun-Bing Wang, Jian-Ying Zhang, Fan Zhang, Yong Zhao, Jian-Ping Gong
This meta-analysis aimed to explore the effectiveness of partial spleen arterial embolization (PSAE) in the treatment of hypersplenism secondary to hepatic cirrhosis. PubMed, Embase, Cochrane Library, Wan Fang, CNKI, Vip, and CBM databases were searched for randomized controlled trials, cohort studies, and case-control studies that compared PSAE with splenectomy in the treatment of hypersplenism secondary to hepatic cirrhosis from their inception to July 25, 2015. Statistical analysis was conducted in Cochrane Network RevMan v5...
March 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28316155/-reevaluation-of-the-methodological-quality-in-meta-analyses-of-accelerated-rehabilitation-on-recovery-after-surgery-for-colorectal-cancer
#16
S N Ding, H Y Pan, J G Zhang
Objective: To evaluate the methodological quality and impacts on outcomes for systematic reviews (SRs) of accelerated rehabilitation versus traditional control for colorectal surgery. Methods: We comprehensively searched six databases and additional websites to collect SRs, or meta-analysis from inception to July 2016. The Overview Quality Assessment Questionnaire (OQAQ) was applied for quality assessment of the included studies, the tools recommended by the Cochrane Collaboration was applied for quality assessment for RCT and CCT and the Newcastle-Ottawa Scale (NOS) was applied to assess observational study...
March 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28315968/the-efficacy-of-bipolar-sealer-on-blood-loss-in-spine-surgery-a-meta-analysis
#17
REVIEW
Tao Lan, Shi-Yu Hu, Xin-Jian Yang, Yang Chen, Yi-Yan Qiu, Wei-Zhuang Guo, Jian-Ze Lin, Kai Ren
OBJECTIVE: The purpose of this meta-analysis of randomized controlled trials (RCTs) and non-RCTs was to gather data to evaluate the efficacy and safety of bipolar sealer versus standard electrocautery in the management of spinal disease. METHODS: The electronic databases including Embase, PubMed and Cochrane library were searched to identify relevant studies published from the time of the establishment of these databases up to January 2017. The primary outcomes were total blood loss, requirement of transfusion (rate and amount), and operation time...
March 18, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28315933/coblation-tonsillectomy-a-systematic-review-and-descriptive-analysis
#18
Christopher Metcalfe, Jameel Muzaffar, Charles Daultrey, Christopher Coulson
Coblation is one of the more recent techniques for tonsillectomy; however, it remains unclear whether it exhibits any benefit or increased risk when compared to other techniques. This review provides an updated assessment of coblation tonsillectomy and how it compares to other tonsillectomy techniques. Systematic review and descriptive analysis of published literature. Electronic searches of MEDLINE, EMBASE, Web of Science and the Cochrane Database were performed. We included all randomized control trials comparing coblation tonsillectomy (not 'tonsillotomy') with any other tonsillectomy technique...
March 18, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28315877/the-value-of-lncrna-hulc-as-a-prognostic-factor-for-survival-of-cancer-outcome-a-meta-analysis
#19
Xian Chen, Limin Lun, Huabin Hou, Runhua Tian, Haiping Zhang, Yunyuan Zhang
AIMS: Growing evidence from recent studies has shown that lncRNA HULC plays a role in the development of multiple carcinomas. This meta-analysis aimed to analyze available data to identify the prognostic value of HULC in multiple tumors. METHODS: A systematic search was performed by using PubMed (medline), Embase, ISI Web of Knowledge, Springer, the Cochrane Library, Scopus, BioMed Central, ScienceDirect, Wanfang, Weipu, and China National Knowledge Internet (CNKI) computerized databases from inception to Nov 30, 2016...
March 17, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28315875/systematic-review-of-exocrine-pancreatic-insufficiency-after-gastrectomy-for-cancer
#20
Jennifer Straatman, Jim Wiegel, Nicole van der Wielen, E P Jansma, Miguel A Cuesta, Donald L van der Peet
BACKGROUND: Survival rates after a total gastrectomy with adequate lymphadenectomy are improving, leading to a shift in outcomes of interest from survival to postoperative outcomes and symptoms. In this systematic review, we investigate gastrointestinal symptoms that occur after a gastrectomy in relation to exocrine pancreatic insufficiency and the effect of pancreatic exocrine enzyme supplementation on these symptoms. METHODS: Online databases PubMed, Embase, and Cochrane Library were systematically searched in accordance with the PRISMA guidelines...
March 18, 2017: Digestive Surgery
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