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https://www.readbyqxmd.com/read/29166553/botulinum-toxin-injection-versus-topical-nitrates-for-chronic-anal-fissure-an-updated-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#1
REVIEW
Shaheel M Sahebally, Babak Meshkat, Stewart R Walsh, David Beddy
BACKGROUND: Chronic anal fissures (CAF) are frequently encountered in coloproctology clinics. Chemical sphincterotomy with pharmacological agents is recommended as first-line therapy. Topical nitrates (TN) heal CAF effectively but recurrences are common. An alternative treatment modality is injection of botulinum toxin (BT) into the anal sphincter. We aimed to perform an updated systematic review and meta-analysis to compare the effectiveness of BT and TN in the management of CAF. METHODS: PubMed, EMBASE and Cochrane databases were searched for relevant articles from inception until March 2017...
November 22, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29166295/nursing-care-of-infants-with-a-ventriculoperitoneal-shunt
#2
Rachel A Joseph, Michaela R Killian, Emily E Brady
BACKGROUND: Infants with congenital or posthemorrhagic hydrocephalus may require a ventriculoperitoneal (VP) shunt to divert the flow of cerebrospinal fluid, thus preventing increase in intracranial pressure. Knowledge on various aspects of caring for a child with a VP shunt will enable new and experienced nurses to better care for these infants and equip parents for ongoing care at home. PURPOSE: To review the nurses' role in care of infants with hydrocephalus, care after VP shunt placement, prevention of complications, and parental preparation for home care...
November 20, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29166260/the-development-and-content-validation-of-a-multidisciplinary-evidence-based-wound-infection-prevention-and-treatment-guideline
#3
Sammy A Zakhary, Chris Davey, Rebecca Bari, Jordan Bean, Tyler Reber, Kathy Gallagher, Kara Couch, Jennifer Hurlow, Karen Laforet, Corrine McIssac, Karen Napier, Diana Vilar-Compte, Emily Zakhary, Michel Hermans, Laura Bolton
Acute and chronic wound infections create clinical, economic, and patient-centered challenges best met by multidisciplinary wound care teams providing consistent, valid, clinically relevant, safe, evidence-based management across settings. To develop an evidence-based wound infection guideline, PubMed, Cochrane Library, and Cumulative Index to Nursing and Allied Health Literature databases were searched from inception through August 1, 2017 using the terms (or synonyms) wound infection and risk factor, significant, diagnosis, prevention, treatment, or surveillance...
November 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/29166151/biomarkers-and-imaging-of-breast-cancer
#4
Olena Weaver, Jessica W T Leung
OBJECTIVE: The goals of this review are to provide background information on the definitions and applications of the general term "biomarker" and to highlight the specific roles of breast imaging biomarkers in research and clinical breast cancer care. A search was conducted of the main electronic biomedical databases (PubMed, Cochrane, Embase, MEDLINE [Ovid], Scopus, and Web of Science). The search was focused on review literature in general radiology and biomedical sciences and on reviews and primary research articles on biomarkers in breast imaging over the 15 years ending in June 2017...
November 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29165784/interventions-for-managing-skeletal-muscle-spasticity-following-traumatic-brain-injury
#5
REVIEW
Anneliese Synnot, Marisa Chau, Veronica Pitt, Denise O'Connor, Russell L Gruen, Jason Wasiak, Ornella Clavisi, Loyal Pattuwage, Kate Phillips
BACKGROUND: Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness, reduced range of movement, broken skin and pain. Treatments for spasticity include a range of pharmacological and non-pharmacological interventions, often used in combination. Management of spasticity following TBI varies from other clinical populations because of the added complexity of behavioural and cognitive issues associated with TBI...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29165173/health-and-well-being-benefits-of-spending-time-in-forests-systematic-review
#6
Byeongsang Oh, Kyung Ju Lee, Chris Zaslawski, Albert Yeung, David Rosenthal, Linda Larkey, Michael Back
BACKGROUND: Numerous studies have reported that spending time in nature is associated with the improvement of various health outcomes and well-being. This review evaluated the physical and psychological benefits of a specific type of exposure to nature, forest therapy. METHOD: A literature search was carried out using MEDLINE, PubMed, ScienceDirect, EMBASE, and ProQuest databases and manual searches from inception up to December 2016. Key words: "Forest" or "Shinrin -Yoku" or "Forest bath" AND "Health" or "Wellbeing"...
October 18, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29164757/considerations-in-fertility-preservation-in-cases-of-genital-trauma
#7
B Z Starmer, A Baird, M A Lucky
OBJECTIVE: To perform a review of the literature to assess the options of preserving fertility in patients with fertility threatening testicular injuries and their efficacy to help guide surgeons who encounter these patients in the future. METHODS: Medline, EMBASE and Cochrane library databases were searched using the keywords treatment, therapy, management, scrotal trauma / injury, testicular trauma / injury / amputation, fertility and fertility preservation Inclusion criteria: studies reporting the fertility preserving techniques with a history of testicular trauma with loss of one, both or nearly all testicular parenchymal tissue RESULTS: Two cases of testicular sperm extraction, eight cases of testicular replantation, and one case of cryopreservation after injury were identified...
November 22, 2017: BJU International
https://www.readbyqxmd.com/read/29164603/18f-pet-with-florbetapir-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#8
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Xavier Bonfill Cosp, Leon Flicker
BACKGROUND: (18)F-florbetapir uptake by brain tissue measured by positron emission tomography (PET) is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using amyloid biomarkers tests like (18)F-florbetapir...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164602/18f-pet-with-flutemetamol-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#9
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Leon Flicker, Xavier Bonfill Cosp
BACKGROUND: (18)F-flutemetamol uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and the confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using some amyloid biomarkers tests like (18)F-flutemetamol...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164600/18f-pet-with-florbetaben-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#10
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Leon Flicker, Xavier Bonfill Cosp
BACKGROUND: (18)F-florbetaben uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using some amyloid biomarkers tests like (18)F-florbetaben...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164533/lower-serum-zinc-concentration-despite-higher-dietary-zinc-intake-in-athletes-a-systematic-review-and-meta-analysis
#11
REVIEW
Anna Chu, Cushla Holdaway, Trishala Varma, Peter Petocz, Samir Samman
BACKGROUND: Zinc is an essential trace element that has been implicated in numerous biological functions, including immunity, energy metabolism and antioxidative processes. Recent evaluations of the literature have provided evidence of significant acute changes in zinc metabolism following a bout of aerobic exercise. OBJECTIVE: The aim of this study was to determine the zinc status of trained athletes compared with control populations, as described in cross-sectional studies...
November 21, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29164528/equivalent-analgesic-effectiveness-between-perineural-and-intravenous-dexamethasone-as-adjuvants-for-peripheral-nerve-blockade-a-systematic-review-and-meta-analysis
#12
REVIEW
Nasir Hussain, Tom Van den Langenbergh, Corey Sermer, Manuel L Fontes, Amit Atrey, Naum Shaparin, Tamara R Sawyer, Amaresh Vydyanathan
PURPOSE: Dexamethasone is commonly used as an adjuvant to local anesthetics for peripheral nerve blockade; however, uncertainty persists regarding its optimal route of administration and safety. A systematic review and meta-analysis of randomized-controlled trials (RCTs) was conducted to compare the incremental benefits of intravenous (IV) vs perineural (PN) dexamethasone when used as adjuvants for peripheral nerve blockade to improve analgesia. SOURCES: A search strategy was developed to identify eligible articles from the Cochrane and National Library of Medicine databases from inception until June 2017...
November 21, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29163987/medial-collateral-ligament-calcification-a-rare-knee-pain-entity-with-literature-review
#13
Md Abu Bakar Siddiq, Israt Jahan
Medial knee pain can originate from both osseous and non-osseous soft tissue structures including medial collateral ligament (MCL), creating a raft for patients' sufferings. Previously published works demonstrated MCL calcification as a rare medial knee pain entity. Alongside physical examination, radio-imaging techniques, namely conventional X-ray, CT/MRI scanning, etc. have been reported to be useful in recognizing MCL calcification. The present study demonstrates MCL calcification in a 60-year-old Asian-Bangladeshi woman, using high frequency diagnostic ultrasonogram and is the first reported study in the literature...
November 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/29163971/dexmedetomidine-vs-propofol-for-gastrointestinal-endoscopy-a-meta-analysis
#14
REVIEW
Toshihiro Nishizawa, Hidekazu Suzuki, Naoki Hosoe, Haruhiko Ogata, Takanori Kanai, Naohisa Yahagi
Background and aim: Several randomized controlled trials have compared sedation with dexmedetomidine and propofol in gastrointestinal endoscopy, with contradictory results. We conducted a meta-analysis of data from randomized controlled trials that compared dexmedetomidine with propofol. Methods: We searched PubMed, the Cochrane library, and the Igaku-chuo-zasshi database for randomized trials eligible for inclusion in our meta-analysis. We identified six eligible randomized trials from the database search, and compared the effect of propofol versus dexmedetomidine with respect to: (a) patient's satisfaction level, (b) body movement or gagging, (c) cardiopulmonary complications, and (d) change in heart rate...
November 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29163836/kinetics-of-plasma-von-willebrand-factor-in-acute-myocardial-infarction-patients-a-meta-analysis
#15
Xia Wang, Junyu Zhao, Yong Zhang, Xiujuan Xue, Jie Yin, Lin Liao, Cuiping Xu, Yinglong Hou, Suhua Yan, Ju Liu
Previous studies have shown a variation in plasma level of von Willebrand factor (vWF) in acute myocardial infarction (AMI) patients but with contentious results. In this study, we performed a meta-analysis to evaluate the kinetics of plasma vWF after AMI. A total of 11 qualified studies were obtained through systematical search in PubMed, Web of science, Cochrane Library database and CNKI, followed by search of reference lists, involving 519 AMI patients and 466 non-AMI controls. The standard mean difference (SMD) and 95% confidence intervals (95% CI) were calculated using random-effects model...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29163833/a-systematic-review-and-meta-analysis-of-effectiveness-and-safety-of-therapy-for-overactive-bladder-using-botulinum-toxin-a-at-different-dosages
#16
Hui-Yun Gu, Ju-Kun Song, Wen-Jun Zhang, Jin Xie, Qi-Sheng Yao, Wen-Jing Zeng, Chao Zhang, Yu-Ming Niu
Purpose: To assess the effectiveness and safety of botulinum toxin A (BTX-A) at different dosages for overactive bladder (OAB). Materials and Methods: The MEDLINE, EMBASE, and Cochrane Controlled Trials Register databases were searched through November 3, 2016 to identify relevant randomized controlled trials (RCTs). Results: Eleven studies were identified in this meta-analysis. Compared with placebo, the urinary incontinence (UI) episodes per week as the primary outcomes, urodynamic parameters including maximum cystometric capacity (MCC), and maximum detrusor pressure (MDP) for neurogenic detrusor overactivity (NDO) at 6 weeks, and for idiopathic detrusor overactivity (IDO) at 36 weeks were evaluated...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29163829/meta-analysis-of-the-prognostic-value-of-lncrna-zfas1-in-patients-with-solid-tumors
#17
Wei Song, Chuan Tian, Run-Jin Zhang, Shu-Bing Zou, Kai Wang
Expression of ZFAS1, a newly identified long noncoding RNA (lncRNA), is dysregulated in several types of cancer. Here we assessed the prognostic value of ZFAS1 in solid tumors. A comprehensive literature search was performed by screening the PubMed, EMBASE, MEDLINE, Cochrane Library, CNKI, and Wanfang databases. A total of 874 patients from 10 studies were included. The pooled analysis demonstrated that patients with high ZFAS1 expression had a significantly shorter overall survival (OS) (HR, 1.58; 95% CI, 1...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29163326/systematic-review-of-traumatic-brain-injuries-in-baseball-and-softball-a-framework-for-prevention
#18
Michael D Cusimano, Alice Zhu
Background: Traumatic brain injuries (TBIs) are an important public health challenge. The classification of baseball and softball as low contact sports and their association with extremity injuries cause individuals to overlook the risk of TBI in baseball and softball. Purpose: To summarize our knowledge of the epidemiology and risk factors of TBIs associated with baseball and softball with an aim to better design and implement preventive strategies. Methods: A search algorithm containing keywords that were synonymous to the terms "TBI," "baseball" was applied to the following nine databases: MEDLINE, Scopus, PubMed, EMBASE, CINAHL, Healthstar, PsychINFO, AMED, Cochrane library...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29162585/diet-behavior-change-techniques-in-type-2-diabetes-a-systematic-review-and-meta-analysis
#19
REVIEW
Kevin A Cradock, Gearóid ÓLaighin, Francis M Finucane, Rhyann McKay, Leo R Quinlan, Kathleen A Martin Ginis, Heather L Gainforth
OBJECTIVE: Dietary behavior is closely connected to type 2 diabetes. The purpose of this meta-analysis was to identify behavior change techniques (BCTs) and specific components of dietary interventions for patients with type 2 diabetes associated with changes in HbA1c and body weight. RESEARCH DESIGN AND METHODS: The Cochrane Library, CINAHL, Embase, PubMed, PsycINFO, and Scopus databases were searched. Reports of randomized controlled trials published during 1975-2017 that focused on changing dietary behavior were selected, and methodological rigor, use of BCTs, and fidelity and intervention features were evaluated...
December 2017: Diabetes Care
https://www.readbyqxmd.com/read/29162558/surgical-interventions-for-the-treatment-of-supracondylar-humerus-fractures-in-children-protocol-of-a-systematic-review
#20
Oreste Lemos Carrazzone, João Carlos Belloti, Fabio Teruo Matsunaga, Nacime Salomão Barbachan Mansur, Marcelo Hide Matsumoto, Flavio Faloppa, Marcel Jun Sugawara Tamaoki
BACKGROUND: The treatment of supracondylar humerus fracture in children (SHFC) is associated with complications such as functional deficit, residual deformity, and iatrogenic neurological damage. The standard treatment is closed reduction and percutaneous Kirschner wire fixation with different configurations. Despite this fact, there is still no consensus on the most effective technique for the treatment of these fractures. OBJECTIVE: The aim of this systematic review will be to evaluate the effect of surgical interventions on the treatment of Gartland type II and III SHFC by assessing function, complications, and error as primary outcomes...
November 21, 2017: JMIR Research Protocols
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