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https://www.readbyqxmd.com/read/29769482/aetiological-factors-of-female-genitourinary-fistula
#1
F Z Aalpona, M Kamrul-Hasan, F Islam, S Hossain, S Akter, K F Ananya
The purpose of this observational cross-sectional study was to evaluate the histories of women with urinary incontinence caused by genitourinary fistulae in Bangladesh. This is an exploratory analysis to investigate possible contributing factors to the development of urogenital fistulae. Sixty four (64) women who were treated for urogenital fistulae at the National Fistula Center, Dhaka Medical College Hospital, Dhaka, Bangladesh were interviewed from July 2013 to December 2013. Their average age was 35.91 years; majorities were illiterate; had early marriage and came from poor family...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29760616/high-frequency-of-primary-hereditary-ichthyoses-in-the-north-east-region-of-cairo-egypt
#2
Nermine El-Sayed, Neveen S Seifeldin, Christine K T Gobrial
Introduction: Inherited ichthyoses are caused by mutations in various genes important for keratinocyte differentiation and epidermal barrier function. Although ichthyoses are rare disorders, they require costly long-term medical management, and thus there is a need for efficient preventive and therapeutic strategies. Aim: We performed a retrospective study to determine the frequency, types, clinical presentation and associated genomic errors of primary hereditary ichthyoses in Egyptian patients and their relatives consulting the Genetics Clinic, Pediatric Hospital, Ain Shams University...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29745249/mitochondrial-dna-analysis-of-mazahua-and-otomi-indigenous-populations-from-estado-de-m%C3%A3-xico-suggests-a-distant-common-ancestry
#3
Angélica González-Oliver, Ernesto Garfias-Morales, David Glenn Smith, Mirsha Quinto-Sánchez
The indigenous Mazahua and Otomi have inhabited the same localities in Estado de México since pre-Columbian times. Their languages, Mazahua and Otomi, belong to the Oto-Manguean linguistic family, and although they share cultural traditions and a regional history that suggest close genetic relationships and common ancestry, the historical records concerning their origin are confusing. To understand the biological relationships between Mazahua and Otomi, we analyzed mitochondrial DNA (mtDNA) genetic variation...
July 2017: Human Biology
https://www.readbyqxmd.com/read/29739244/the-relationship-between-some-neonatal-and-maternal-factors-during-pregnancy-with-the-prevalence-of-congenital-malformations-in-iran-a-systematic-review-and-meta-analysis
#4
Salman Daliri, Hamid Safarpour, Jafar Bazyar, Kourosh Sayehmiri, Arezoo Karimi, Rahman Anvary
INTRODUCTION: Congenital malformations are one of the main causes of death and disability in children. These malformations arise during embryogenesis and fetal development during pregnancy due to exposure to some environmental factors and genetic mutations. Given the high prevalence of congenital malformations in Iran, the current study was conducted to investigate the relationship between some neonatal and maternal factors during pregnancy with the prevalence of congenital malformations in Iran...
May 8, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29730657/adolescent-undernutrition-global-burden-physiology-and-nutritional-risks
#5
Parul Christian, Emily R Smith
Adolescents, comprised of 10-19 year olds, form the largest generation of young people in our history. There are an estimated 1.8 billion adolescents in the world, with 90% residing in low- and middle-income countries. The burden of disease among adolescents has its origins in infectious and injury-related causes, but nutritional deficiencies, suboptimal linear growth, and undernutrition are major public health problems, even as overweight may be on the rise in many contexts. Summary and Key Messages: Girls are most vulnerable to the influences of cultural and gender norms, which often discriminate against them...
May 4, 2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29693968/determinants-of-breast-cancer-screening-by-mammography-in-women-referred-to-health-centers-of-urmia-iran
#6
Fatemeh Moghaddam Tabrizi, Sakineh Vahdati, Shahriar Khanahmadi, Samira Barjasteh
Background: In women, breast cancer accounts for 30 percent of all cancers and it is the second leading cause of mortality. Mammography is considered an effective procedure to detect early breast cancer recommended by World Health Organization. This study was aimed to evaluate breast cancer screening determinants in women referred to health centers of Urmia for mammography in 2017. Materials and Methods: In this descriptive-analytic cross-sectional study, 348 women referred to health centers of Urmia were selected using multistage sampling...
April 25, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29693034/studying-the-determinant-factors-leading-to-congenital-heart-disease-in-newborns
#7
Mohammadhossein Arjmandnia, Mahsa Besharati, Sajad Rezvan
CONTEXT: Congenital heart disease (CHD) is an important cause of death during the 1st year of life and includes a special group of cardiac diseases that exist from birth. These conditions arise due to the abnormal development of an embryo's normal structures. AIMS: A case-control study was conducted to investigate the determinant factors leading to CHD. MATERIALS AND METHODS: All newborns who have been diagnosed with CHD upon echocardiography in 2013 were considered as cases...
2018: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29691789/impact-of-cancer-on-romantic-relationships-among-young-adults-a-systematic-review
#8
REVIEW
Carolyn Rabin
The aim of this review was to determine the impact of a cancer diagnosis and history on young adults' ability to initiate and maintain romantic relationships. MedLine and PsycInfo databases were used to identify articles that address dating, romantic relationships, or marriage among 18- to 45-year-old cancer survivors. Twenty-one relevant articles were identified. Findings indicate that young adult cancer survivors struggle with when/how to disclose their cancer history to potential partners, are delayed in initiating their first romantic relationships, have fewer romantic relationships than peers, and are less likely than peers to marry...
April 24, 2018: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/29663531/identification-of-variants-in-the-mitochondrial-lysine-trna-mt-tk-gene-in-myoclonic-epilepsy-pathogenicity-evaluation-and-structural-characterization-by-in-silico-approach
#9
Muhammad S Nadeem, Habib Ahmad, Kaleemuddin Mohammed, Khushi Muhammad, Inam Ullah, Othman A S Baothman, Nasir Ali, Firoz Anwar, Mazin A Zamzami, Abdul Rauf Shakoori
Variations in mitochondrial genes have an established link with myoclonic epilepsy. In the present study we evaluated the nucleotide sequence of MT-TK gene of 52 individuals from 12 unrelated families and reported three variations in 2 of the 13 epileptic patients. The DNA sequences coding for MT-TK gene were sequenced and mutations were detected in all participants. The mutations were further analyzed by the in silico analysis and their structural and pathogenic effects were determined. All the investigated patients had symptoms of myoclonus, 61...
April 16, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29629049/risk-factors-associated-with-congenital-hypothyroidism-a-case-control-study-in-southeast-iran
#10
Mohammad Khammarnia, Fariba Ramezani Siakhulak, Hossein Ansari, Mostafa Peyvand
Background and aim: Congenital hypothyroidism (CH) is known as one of the most common preventable cause of mental retardation. This study aimed to determine factors associated with CH in Iran. Methods: This case-control study was conducted on 160 children under one year old in Zahedan in southeast Iran in 2016. The neonates who were born from March 1, 2015 to March 19, 2016 and had undergone a screening program for CH were the study population. The neonates with serum TSH > 10mIu/L and T4 < 6...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29614848/outcomes-of-mitochondrial-derived-diseases-a-single-center-experience
#11
Sahin Erdol, Halil Saglam
BACKGROUND: The purpose of this study is to help elucidate which part of the mitochondria is causing a problem through anamnesis, physical examination, and routine biochemical tests in the event of a suspected mitochondrial disease case. METHODS: The data were obtained retrospectively from the medical records of 75 cases; the mitochondrial-derived disease (MDD) cases were observed in our center from 2011 to 2017. RESULTS: The most commonly observed MDDs were oxidative phosphorylation disorders at 44%, followed by fatty acid oxidation disorder at 40%, pyruvate metabolism disorder at 12%, and ketone metabolism disorder at 4%, respectively...
March 28, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29610672/work-hour-trajectories-and-depressive-symptoms-among-midlife-and-older-married-couples
#12
Wylie H Wan, Toni C Antonucci, Kira S Birditt, Jacqui Smith
Life course theories highlight the importance of understanding psychological health of aging individuals in context. Work and marriage are influential contexts in later life that are increasingly relevant because both spouses of many households work and individuals are delaying retirement. Although there is extensive literature on predictors of depressive symptoms, incorporating life course histories of work and social contexts has been a critical omission in the aging and health field. This study identifies couples' work trajectories as a function of husband's and wife's weekly work hours and examines the link between couple work-hour trajectory membership and individual depressive symptoms...
January 2018: Work, Aging and Retirement
https://www.readbyqxmd.com/read/29499514/bilateral-split-hand-foot-malformation-in-siblings-case-series
#13
Mohammed Ashi, Rehab Assur, Basim Awan, Hattan Aljaaly
INTRODUCTION: Split Hand-Foot malformation (SHFM) is a congenital limb defect that affects the central rays of the hands and/or feet. It is a rare condition that has genetic and environmental etiologies. It ranges in severity depending on the extent of the malformation. We report on two siblings with severe SHFM affecting all limbs. METHODS: We described two cases of siblings with SHFM and discuss the possible causes of the condition. This research did not require ethical approval due to the institute not requiring it for this type of study...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29445638/comparison-characteristics-of-family-and-demographic-of-children-with-antenatal-hydronephrosis-between-2-nd-and-3-rd-trimesters-of-gestation
#14
Maryam Nazemipour, Abdol-Mohammad Kajbafzadeh, Kazem Mohammad, Abbas Rahimi Foroushani, Asal Hojjat, Maryam Seyedtabib, Ali Nazemipour, Mahmood Mahmoudi
Background: The aim of this study was comparison characteristics of family and demographics of children with antenatal hydronephrosis, in 2nd and 3rd trimester of pregnancy, in order to the need for postnatal management. Methods: This cross-sectional study described some information from family of children with antenatal hydronephrosis, at the Pediatric Urology Research Center of Children's Hospital Medical Center of Tehran University of Medical Sciences. Data for 193 children, admitted in 2012-2013, were collected retrospectively...
February 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29443635/race-differences-in-linking-family-formation-transitions-to-women-s-mortality
#15
Adriana M Reyes, Melissa Hardy, Eliza Pavalko
We examine how the timing and sequencing of first marriage and childbirth are related to mortality for a cohort of 4,988 white and black women born between 1922 and 1937 from the National Longitudinal Survey of Mature Women. We use Cox proportional hazard models to estimate race differences in the association between family formation transitions and mortality. Although we find no relationships between marital histories and longevity, we do find that having children, the timing of first birth, and the sequencing of childbirth and marriage are associated with mortality...
February 1, 2018: Journal of Health and Social Behavior
https://www.readbyqxmd.com/read/29430150/on-the-origins-of-the-semen-analysis-a-close-relationship-with-the-history-of-the-reproductive-medicine
#16
REVIEW
Fernando Tadeu Andrade-Rocha
The spermatozoa were first seen in ejaculates in the 17th century. However, the basic mechanisms of human fertilization have been only fully understood after the discovery of ovum in 1827. As a result, the interest in developing technologies for semen analysis arose from the early 1900s. Indeed, standard methodologies for semen analysis were designed mostly along the first half of the 20th century. Before the 1930s, semen analysis was nearly unavailable clinically, since there were still no robust methodologies for assessing sperm characteristics, as well as to set up standard references that could be able to assess the reproductive capacity of men...
October 2017: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29417130/the-origin-of-spousal-resemblance-for-alcohol-use-disorder
#17
Kenneth S Kendler, Sara Larsson Lönn, Jessica Salvatore, Jan Sundquist, Kristina Sundquist
Importance: Although spouses strongly resemble one another in their risk for alcohol use disorder (AUD), the causes of this association remain unclear. Objectives: To examine longitudinally, in first marriages, the association of a first registration for AUD in one spouse with risk of registration in his or her partner and to explore changes in the risk for AUD registration in individuals with multiple marriages as they transition from a spouse with AUD to one without or vice versa...
March 1, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29402337/completed-fertility-during-the-twentieth-century-an-example-from-six-settlements-in-northern-greece
#18
Konstantinos N Zafeiris, Stamatina Kaklamani
This study aimed to delineate temporal trends and differentials of completed fertility and their relationship with some characteristics of the marriage system in specific anthropological populations of northern Greece. The analysis was based on the life history of quinquennial and decennial birth cohorts of married women born in the 20th century who reproduced solely within the settlements studied. The variables studied were: children ever born, mean age of mother at first marriage, mean age of mother at first child (live birth), mean age of mother at last child and reproductive span...
February 6, 2018: Journal of Biosocial Science
https://www.readbyqxmd.com/read/29389703/association-between-cleft-lip-and-or-cleft-palate-and-family-history-of-cancer-a-case-control-study
#19
Anthony H Bui, Ayisha Ayub, Mairaj K Ahmed, Emanuela Taioli, Peter J Taub
BACKGROUND: Cleft lip and/or cleft palate (CL ± P) are among the most common congenital anomalies. Nevertheless, their etiologies remain poorly understood. Several studies have demonstrated increased rates of cancer among patients with CL ± P and their relatives, as well as increased risk of CL ± P among family members of cancer survivors. In addition, a number of possible genetic associations between cancer and CL ± P have been identified. However, these studies are limited by confounding factors that may be prevalent in these patients, such as tobacco exposure and perinatal complications...
April 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29389674/inherited-factor-ii-deficiency-with-paradoxical-hypercoagulability-a-case-report
#20
Harold Watson, Ariel Perez, Kwabena Ayesu, Faisal Musa, Jose Sarriera, Mario Madruga, Steve J Carlan
: Congenital deficiency of factor II is a very rare autosomal recessive disorder that can result in a bleeding diathesis. Genotypically, individuals are either homozygous for a defective prothrombin gene or a compound heterozygote with different mutated prothrombin genes inherited from each parent. Phenotypically, it is characterized by either a low production of normal prothrombin or a near-normal production of dysfunctional prothrombin. Treatment is aimed at restoring normally functioning factor II circulating levels to sufficient concentration for hemostasis...
March 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
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