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https://www.readbyqxmd.com/read/29017808/a-novel-technique-for-duplex-guided-office-based-interventions-for-patients-with-acute-arteriovenous-fistula-occlusion
#1
Afsha Aurshina, Enrico Ascher, Anil Hingorani, Natalie Marks
OBJECTIVE: The purpose of the study was to aggressively salvage acutely occluded arteriovenous fistulas (AVFs) using duplex imaging as the sole imaging modality for percutaneous transluminal angioplasty of acutely thrombosed AVF. METHODS: Over a period of 12 months, 14 patients with acute thrombosis of their AVFs underwent 18 procedures in a single center for AVF salvage. All 14 patients presented with chronic renal failure, and six were diabetic. All patients were treated under duplex guidance alone...
October 7, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28899228/intraoperative-venoplasty-to-facilitate-placement-of-tunneled-catheters-for-hemodialysis
#2
Afsha Aurshina, Anil Hingorani, Natalie Marks, Enrico Ascher
Objective With the implementation of the K-DOQI guidelines, more patients are in need of long-term dialysis catheters until maturation of the arteriovenous fistula. However, on occasion, when placing a tunneled cuffed catheter for hemodialysis, we have encountered difficulty with passing the guidewire in spite of demonstration of a patent cervical portion of the internal jugular vein on duplex. Herein, we review our experience with intraoperative venoplasty for placement of Tesio™ catheters (Medcomp Harleysville, PA)...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28790050/anaphylaxis-after-disinfection-with-2-chlorhexidine-wand-applicator
#3
Sameer Bahal, Samriti Sharma, Lene Heise Garvey, Vasantha Nagendran
A 54-year-old man with end-stage renal failure attended for dialysis. Within seconds of applying 2% w/v chlorhexidine (ChloraPrep 3 mL Wand Applicator) to the skin surrounding the insertion point of his dialysis catheter (Tesio catheter), he developed pruritus, urticaria, shortness of breath, hypotension and reduced responsiveness. Treatment for anaphylaxis was initiated with rapid improvement of his symptoms, and he made a full recovery. Allergy to chlorhexidine was confirmed with skin testing, and the patient was warned against all future exposure to chlorhexidine...
August 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28747268/screening-of-depression-in-cardiology-a-study-on-617-cardiovascular-patients
#4
Valentina Tesio, Sebastiano Marra, Stefania Molinaro, Riccardo Torta, Fiorenzo Gaita, Lorys Castelli
BACKGROUND: Depression screening in the cardiovascular disease (CVD) care setting is under-performed, also because the issue of the optimal screening tools cut-off is still open. We analysed which HADS (Hospital Anxiety and Depression Scale) total score cut-off value shows the best properties in two groups of 357 Acute Coronary Syndrome (ACS) and 260 Chronic Coronary Artery Disease (CAD) hospitalized patients. METHODS: A Receiver Operating Characteristics (ROC) curve was plotted for both groups using the Montgomery-Asberg Depression Rating Scale (MADRS) as the criterion...
July 20, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28719477/gait-analysis-on-force-treadmill-in-children-comparison-with-results-from-ground-based-force-platforms
#5
Luigi Tesio, Chiara Malloggi, Nicola M Portinaro, Luigi Catino, Nicola Lovecchio, Viviana Rota
Gait analysis (GA) typically includes surface electromyographic (sEMG) recording from several lower limb muscles, optoelectronic measurement of joint rotations, and force recordings from ground-based platforms. From the latter two variables, the muscle power acting on the lower limb joints can be estimated. Recently, gait analysis on a split-belt force treadmill (GAFT) was validated for the study of adult walking. It showed high reliability of spatiotemporal, kinematic, dynamic, and sEMG parameters, matching those obtainable with GA on the basis of ground walking...
July 17, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28681716/psychosomatic-syndromes-in-fibromyalgia
#6
Ada Ghiggia, Riccardo Torta, Valentina Tesio, Marialaura Di Tella, Annunziata Romeo, Fabrizio Colonna, Giuliano Carlo Geminiani, Enrico Fusaro, Alberto Batticciotto, Lorys Castelli
OBJECTIVES: The aim of this study was to compare the prevalence of psychosomatic symptoms in patients with fibromyalgia (FM) or rheumatoid arthritis (RA). METHODS: Seventy-six consecutive women with FM and 80 with RA without concomitant FM were assessed using the Diagnostic Criteria for Psychosomatic Research (DCPR) interview to evaluate the presence of psychosomatic syndromes. Beck Depression Inventory - II (BDI-II) and Form Y of the State-Trait Anxiety Inventory (STAI-Y) were administered in order to assess the symptoms of anxiety and depression...
May 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28592888/tcr%C3%AE-rearrangements-identify-a-subgroup-of-nkl-deregulated-adult-t-alls-associated-with-favorable-outcome
#7
P Villarese, C Lours, A Trinquand, S Le Noir, M Belhocine, L Lhermitte, A Cieslak, M Tesio, A Petit, M LeLorch, S Spicuglia, N Ifrah, H Dombret, A W Langerak, N Boissel, E Macintyre, V Asnafi
T-cell acute lymphoblastic leukemia (T-ALL) results from leukemic transformation of T-cell precursors arrested at specific differentiation stages, including an 'early-cortical' thymic maturation arrest characterized by expression of cytoplasmic TCRβ but no surface T-cell receptor (TCR) and frequent ectopic expression of the TLX1/3 NK-like homeotic proteins (NKL). We designed a TCRα VJC PCR to identify clonal TCRα rearrangements in 32% of 127 T-ALLs, including 0/52 immature/TCRγδ lineage cases and 41/75 (55%) TCRαβ lineage cases...
June 8, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/28577473/alexithymia-and-depression-in-patients-with-fibromyalgia-when-the-whole-is-greater-than-the-sum-of-its-parts
#8
Ada Ghiggia, Annunziata Romeo, Valentina Tesio, Marialaura Di Tella, Fabrizio Colonna, Giuliano Carlo Geminiani, Enrico Fusaro, Lorys Castelli
This study investigated the link between alexithymia and depressive symptoms in Fibromyalgia (FM). 181 FM women and 181 healthy controls (HC) were compared using the Hospital Anxiety and Depression Scale and the Toronto Alexithymia Scale. A moderation analysis was performed to examine the moderation effect of the group (FM vs. HC) on the relationship between alexithymia and depression. Group was a significant moderator, highlighting a stronger relationship between alexithymia and depressive symptoms in the FM compared to HC...
September 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28574860/crouch-gait-can-be-an-effective-form-of-forced-use-no-constraint-exercise-for-the-paretic-lower-limb-in-stroke
#9
Luigi Tesio, Viviana Rota, Chiara Malloggi, Luigia Brugliera, Luigi Catino
In hemiplegic gait the paretic lower limb provides less muscle power and shows a briefer stance compared with the unaffected limb. Yet, a longer stance and a higher power can be obtained from the paretic lower limb if gait speed is increased. This supports the existence of a 'learned non-use' phenomenon, similar to that underlying some asymmetric impairments of the motion of the eyes and of the upper limbs. Crouch gait (CG) (bent-hip bent-knee, about 30° minimum knee flexion) might be an effective form of 'forced-use' treatment of the paretic lower limb...
September 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28539671/age-related-clinical-and-biological-features-of-pten-abnormalities-in-t-cell-acute-lymphoblastic-leukaemia
#10
M Tesio, A Trinquand, P Ballerini, G Hypolite, L Lhermitte, A Petit, N Ifrah, A Baruchel, H Dombret, E Macintyre, V Asnafi
The tumour suppressor gene PTEN is commonly altered in T-cell acute lymphoblastic leukaemia but its prognostic impact is still debated. We screened a cohort of 573 fully characterized adult and paediatric T-ALL patients for genomic PTEN abnormalities. PTEN inactivating mutations and/or deletions were identified in 91 cases (16%), including 18% of paediatric (49/277) and 14% of adult cases (42/296). Thirty-four patients harboured only mutations, 12 cases demonstrated only large deletions and 9 only micro-deletions...
May 25, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/28479188/vitamin-a-retinoic-acid-signaling-regulates-hematopoietic-stem-cell-dormancy
#11
Nina Cabezas-Wallscheid, Florian Buettner, Pia Sommerkamp, Daniel Klimmeck, Luisa Ladel, Frederic B Thalheimer, Daniel Pastor-Flores, Leticia P Roma, Simon Renders, Petra Zeisberger, Adriana Przybylla, Katharina Schönberger, Roberta Scognamiglio, Sandro Altamura, Carolina M Florian, Malak Fawaz, Dominik Vonficht, Melania Tesio, Paul Collier, Dinko Pavlinic, Hartmut Geiger, Timm Schroeder, Vladimir Benes, Tobias P Dick, Michael A Rieger, Oliver Stegle, Andreas Trumpp
Dormant hematopoietic stem cells (dHSCs) are atop the hematopoietic hierarchy. The molecular identity of dHSCs and the mechanisms regulating their maintenance or exit from dormancy remain uncertain. Here, we use single-cell RNA sequencing (RNA-seq) analysis to show that the transition from dormancy toward cell-cycle entry is a continuous developmental path associated with upregulation of biosynthetic processes rather than a stepwise progression. In addition, low Myc levels and high expression of a retinoic acid program are characteristic for dHSCs...
May 18, 2017: Cell
https://www.readbyqxmd.com/read/28408875/apas-constraints-to-voluntary-movements-the-case-for-limb-movements-coupling
#12
REVIEW
Fausto G Baldissera, Luigi Tesio
When rhythmically moving two limbs in either the same or in opposite directions, one coupling mode meets constraints that are absent in the other mode. Isodirectional (ISO) flexion-extensions of the ipsilateral hand and foot can be easily performed with either the hand prone or supine. Instead, antidirectional (ANTI) movements require attentive effort and irresistibly tend to reverse into ISO when frequency increases. Experimental evidence indicates that the direction dependent easy-difficult dichotomy is caused by interference of the anticipatory postural commands associated to movements of one limb with voluntary commands to the other limb...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28286493/attachment-style-and-chronic-pain-toward-an-interpersonal-model-of-pain
#13
Annunziata Romeo, Valentina Tesio, Gianluca Castelnuovo, Lorys Castelli
Chronic pain (CP) is a burdensome symptom. Different psychological models have been proposed to explain the role of psychological and social factors in developing and maintaining CP. Attachment, for example, is a psychological construct of possible relevance in CP. The first studies on the role of attachment in CP did not investigate the partner's psychological factors, thus neglecting the influence of the latter. The main aim of this mini-review was to examine the more recent literature investigating the relationship between CP and attachment style...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28235422/crying-spells-triggered-by-thumb-index-rubbing-after-thalamic-stroke-a-case-report
#14
R Bassani, C Rosazza, L Ghirardin, V Caldiera, E Banco, C Casati, L Tesio
BACKGROUND: Pathologic crying, devoid of any emotional counterpart, is known to occur as a consequence of various brain stem, cortical hemispheric and cerebellar lesions or, quite exceptionally, of "dacrystic" epilepsy. The case reported here suggests that thalamic lesions may also cause crying spells, under the special circumstances described below. CASE PRESENTATION: After a mild left thalamic stroke a caucasian 77 years old man presented with crying spells with no emotional counterpart, triggered by thumb-index rubbing of his right hand...
February 24, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28207426/psychological-characteristics-of-early-stage-melanoma-patients-a-cross-sectional-study-on-204-patients
#15
Valentina Tesio, Simone Ribero, Lorys Castelli, Stefania Bassino, Paolo Leombruni, Virginia Caliendo, Marcella Grassi, Danilo Lauro, Giuseppe Macripò, Riccardo G V Torta
The presence of psychological distress has a negative impact not only on cancer patients' quality of life but also on the course of the disease, with slower recovery and increased morbidity. These issues are of particular importance in melanoma patients (MP), who remain at risk of disease progression for many years after diagnosis. This study aimed to investigate psychological distress, coping strategies, and their possible relationships with demographic-clinical features in patients with early-stage melanoma in follow-up...
June 2017: Melanoma Research
https://www.readbyqxmd.com/read/28145810/post-traumatic-growth-distress-and-attachment-style-among-women-with-breast-cancer
#16
Annunziata Romeo, Ada Ghiggia, Valentina Tesio, Marialaura Di Tella, Riccardo Torta, Lorys Castelli
Identifying factors fostering post-traumatic growth (PTG) is very important to promote PTG itself through specific psychological interventions. To this end, we investigated PTG and its relationship with clinical and psychological variables in a sample of 108 female breast cancer survivors. Results showed that women with higher depressive symptoms presented lower levels of PTG than women without. Moreover, women who had undergone combined treatment presented higher levels of PTG than women who had not. The results highlighted the resulting importance of psychological intervention focusing on depressive symptoms, which negatively interfere with the patients' psychological growth...
May 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/27922597/baboon-envelope-pseudotyped-lentiviral-vectors-a-highly-efficient-new-tool-to-genetically-manipulate-t-cell-acute-lymphoblastic-leukaemia-initiating-cells
#17
C Costa, G Hypolite, O Bernadin, C Lévy, F-L Cosset, V Asnafi, E Macintyre, E Verhoeyen, M Tesio
No abstract text is available yet for this article.
April 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/27899804/casein-kinase-2-controls-the-survival-of-normal-thymic-and-leukemic-%C3%AE-%C3%AE-t-cells-via-promotion-of-akt-signaling
#18
S T Ribeiro, M Tesio, J C Ribot, E Macintyre, J T Barata, B Silva-Santos
The thymus is the major site for normal and leukemic T-cell development. The dissection of the molecular determinants of T-cell survival and differentiation is paramount for the manipulation of healthy or transformed T cells in cancer (immuno)therapy. Casein kinase 2 (CK2) is a serine/threonine protein kinase whose anti-apoptotic functions have been described in various hematological and solid tumors. Here we disclose an unanticipated role of CK2 in healthy human thymocytes that is selective to the γδ T-cell lineage...
July 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/27750065/pain-experience-in-fibromyalgia-syndrome-the-role-of-alexithymia-and-psychological-distress
#19
Marialaura Di Tella, Ada Ghiggia, Valentina Tesio, Annunziata Romeo, Fabrizio Colonna, Enrico Fusaro, Riccardo Torta, Lorys Castelli
BACKGROUND: Fibromyalgia (FM) is a chronic pain syndrome with a high prevalence of alexithymia, a personality disposition that affects emotional self-awareness. The present study aimed to investigate the relationship between alexithymia and pain, differentiating between the sensory and affective components of pain experience, in a sample of FM patients. METHODS: One hundred and fifty-nine FM patients completed a battery of tests assessing pain experience, pain intensity, alexithymia and psychological distress...
January 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27687515/psychological-distress-and-coping-in-nasopharyngeal-cancer-an-explorative-study-in-western-europe
#20
Ada Ghiggia, Lorys Castelli, Giuseppe Riva, Valentina Tesio, Erica Provenzano, Mattia Ravera, Massimiliano Garzaro, Giancarlo Pecorari, Pierfrancesco Franco, Ilenia Potenza, Monica Rampino, Riccardo Torta
Nasopharyngeal carcinoma (NPC) is the head and neck cancer with the greatest impact on patients' quality of life. The aim of this explorative study is to investigate the psychological distress, coping strategies and quality of life of NPC patients in the post-treatment observation period. Twenty-one patients disease-free for at least two years were assessed with a medical and a psycho-oncological evaluation. Clinically relevant depressive symptoms (CRD) were present in 23.8% of patients and 33.3% reported clinically relevant anxiety symptoms (CRA)...
August 10, 2016: Psychology, Health & Medicine
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