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https://www.readbyqxmd.com/read/29217815/effects-of-nicotine-and-tocotrienol-rich-fraction-supplementation-on-cytoskeletal-structures-of-murine-pre-implantation-embryos
#1
Nurul Kamsani Hamirah, Yuhaniza Shafinie Kamsani, Nor-Ashikin Mohamed Nor Khan, Sharaniza Ab Rahim, Mohd Hamim Rajikin
BACKGROUND Cytoskeletal structures, in particular actin and tubulin, provide a fundamental framework in all cells, including embryos. The objective of this study was to evaluate the effects of nicotine, which is a source of oxidative stress, and subsequent supplementation with Tocotrienol-rich fraction (TRF) on actin and tubulin of 2- and 8-cell murine embryos. MATERIAL AND METHODS Thirty female Balb/C mice were divided into 4 groups: Group 1 received: subcutaneous (sc) injection of 0.9% NaCl; Group 2 received sc injection of 3...
December 8, 2017: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/29216868/socio-demographic-determinants-and-effect-of-structured-personal-diabetes-care-a-19-year-follow-up-of-the-randomized-controlled-study-diabetes-care-in-general-practice-dcgp
#2
Andreas Heltberg, Volkert Siersma, John Sahl Andersen, Christina Ellervik, Henrik Brønnum-Hansen, Jakob Kragstrup, Niels de Fine Olivarius
BACKGROUND: We investigated how four aspects of socio-demography influence the effectiveness of an intervention with structured personal diabetes care on long-term outcomes. METHODS: The Diabetes Care in General Practice (DCGP) study is a cluster-randomized trial involving a population-based sample of 1381 patients with newly diagnosed type 2-diabetes mellitus. We investigated how education, employment, cohabitation status and residence influenced the effectiveness of 6 years of intervention with structured personal diabetes care, resembling present day recommendations...
December 8, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/29208892/discrete-and-continuous-mechanisms-of-temporal-selection-in-rapid-visual-streams
#3
Sébastien Marti, Stanislas Dehaene
Humans can reliably detect a target picture even when tens of images are flashed every second. Here we use magnetoencephalography to dissect the neural mechanisms underlying the dynamics of temporal selection during a rapid serial visual presentation task. Multivariate decoding algorithms allow us to track the overlapping brain responses induced by each image in a rapid visual stream. The results show that temporal selection involves a sequence of gradual followed by all-or-none stages: (i) all images first undergo the same parallel processing pipeline; (ii) starting around 150 ms, responses to multiple images surrounding the target are continuously amplified in ventral visual areas; (iii) only the images that are subsequently reported elicit late all-or-none activations in visual and parietal areas around 350 ms...
December 5, 2017: Nature Communications
https://www.readbyqxmd.com/read/29204805/the-epidemiology-of-depressive-symptoms-and-poor-sleep-findings-from-the-english-longitudinal-study-of-ageing-elsa
#4
Lydia Poole, Marta Jackowska
PURPOSE: The reasons for the comorbidity between depressed mood and poor sleep are not well understood. METHOD: Participants were 5172 adults aged 50 years and older from the English Longitudinal Study of Ageing. Sleep was measured via self-report and depressive symptoms using the Centre for Epidemiological Studies Depression scale. RESULTS: Greater depressive symptoms and sleep complaints were associated with female sex, non-cohabitation, relative poverty, smoking, infrequent physical activity, infrequent alcohol consumption, higher body mass index (BMI), diagnosis of hypertension, coronary heart disease, diabetes/high blood glucose, pulmonary disease, arthritis, and higher levels of fibrinogen and C-reactive protein (all p < 0...
December 4, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29204125/alcohol-s-effects-on-pair-bond-maintenance-in-male-prairie-voles
#5
Andre T Walcott, Andrey E Ryabinin
Alcohol abuse can have devastating effects on social relationships. In particular, discrepant patterns of heavy alcohol consumption are associated with increased rates of separation and divorce. Previous studies have attempted to model these effects of alcohol using socially monogamous prairie voles. These studies showed that alcohol consumption can inhibit the formation of pair bonds in this species. While these findings indicated that alcohol's effects on social attachments can involve biological mechanisms, the formation of pair bonds does not properly model long-term human attachments...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29190769/measuring-couple-relationship-quality-in-a-rural-african-population-validation-of-a-couple-functionality-assessment-tool-in-malawi
#6
Allison Ruark, Rachel Chase, John Hembling, Valerie Rhoe Davis, Paul Clayton Perrin, Dorothy Brewster-Lee
Available data suggest that individual and family well-being are linked to the quality of women's and men's couple relationships, but few tools exist to assess couple relationship functioning in low- and middle-income countries. In response to this gap, Catholic Relief Services has developed a Couple Functionality Assessment Tool (CFAT) to capture valid and reliable data on various domains of relationship quality. This tool is designed to be used by interventions which aim to improve couple and family well-being as a means of measuring the effectiveness of these interventions, particularly related to couple relationship quality...
2017: PloS One
https://www.readbyqxmd.com/read/29190680/identifying-social-factors-amongst-older-individuals-in-linked-electronic-health-records-an-assessment-in-a-population-based-study
#7
Anu Jain, Albert J van Hoek, Jemma L Walker, Rohini Mathur, Liam Smeeth, Sara L Thomas
Identification and quantification of health inequities amongst specific social groups is a pre-requisite for designing targeted healthcare interventions. This study investigated the recording of social factors in linked electronic health records (EHR) of individuals aged ≥65 years, to assess the potential of these data to identify the social determinants of disease burden and uptake of healthcare interventions. Methodology was developed for ascertaining social factors recorded on or before a pre-specified index date (01/01/2013) using primary care data from Clinical Practice Research Datalink (CPRD) linked to hospitalisation and deprivation data in a cross-sectional study...
2017: PloS One
https://www.readbyqxmd.com/read/29190365/a-national-portrait-of-stepfamilies-in-later-life
#8
I-Fen Lin, Susan L Brown, Cassandra Jean Cupka, Deborah Carr
Objectives: Scholars have documented increases in the prevalence and complexity of stepfamilies earlier in the life course, but no one has systematically investigated U.S. stepfamily structure in later life. Guided by a family systems approach, we described the prevalence and composition of later-life stepfamilies. Method: The analysis was based on 6,250 married and cohabiting couples participating in the 2012 Health and Retirement Study. We identified the prevalence of later-life stepfamilies, decomposed stepfamily structures, and compared the sociodemographic characteristics and relationship quality of the couples in stepfamilies with those in married families (with only joint children and no stepchildren), paying attention to differences between married and cohabiting stepfamilies...
November 28, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29181136/feasibility-and-effectiveness-of-tuberculosis-active-case-finding-among-children-living-with-tuberculosis-relatives-a-cross-sectional-study-in-guinea-bissau
#9
L Bosa, L Da Silva, D V Mendes, A Sifna, M Sargento Mendes, F Riccardi, R Colombatti
Background and objectives: The World Health Organization End tuberculosis (TB) Strategy, approved in 2014, aims at a 90% reduction in TB deaths and an 80% reduction in TB incidence rate by 2030. One of the suggested interventions is the systematic screening of people with suspected TB, belonging to specific risk groups. The Hospital Raoul Follereau (HRF) in Bissau, Guinea-Bissau, is the National Reference Hospital for Tuberculosis and Lung Disease of the country. We performed an active case-finding program among pediatric age family members and cohabitants of admitted adult TB patients, from January to December 2013...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/29180836/skin-immune-landscape-inside-and-outside-the-organism
#10
REVIEW
Florence Abdallah, Lily Mijouin, Chantal Pichon
The skin is an essential organ to the human body protecting it from external aggressions and pathogens. Over the years, the skin was proven to have a crucial immunological role, not only being a passive protective barrier but a network of effector cells and molecular mediators that constitute a highly sophisticated compound known as the "skin immune system" (SIS). Studies of skin immune sentinels provided essential insights of a complex and dynamic immunity, which was achieved through interaction between the external and internal cutaneous compartments...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29179658/short-and-long-term-effects-of-divorce-and-separation-on-housing-tenure-in-england-and-wales
#11
Júlia Mikolai, Hill Kulu
This paper investigates the effects of marital and non-marital separation on individuals' housing tenure in England and Wales. We apply competing risks event history models to data from the British Household Panel Survey and the UK Household Longitudinal Study to analyse the risk of a residential move to different tenure types, for single, married, cohabiting, and separated men and women. Separated individuals are more likely to move and experience a tenure change than those who are single or in a relationship...
November 28, 2017: Population Studies
https://www.readbyqxmd.com/read/29173542/regression-models-to-assess-the-risk-factors-of-canine-gastrointestinal-parasitism
#12
I Symeonidou, A Ι Gelasakis, K V Arsenopoulos, R Schaper, E Papadopoulos
Gastrointestinal parasites, protozoa and helminths, remain a common important finding in dogs presented to veterinary medical practices. Moreover, dogs may play an active role in the transmission of enteric parasites to humans, given their cohabitation, making canine gastrointestinal parasitism an issue of major concern for public health. To get an overview of the current state of canine gastrointestinal parasites' prevalence in Greece, a total of 1036 faecal samples were collected from dogs either presented in veterinary clinics or in animal shelters...
December 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29172607/social-isolation-health-literacy-and-mortality-risk-findings-from-the-english-longitudinal-study-of-ageing
#13
Samuel G Smith, Sarah E Jackson, Lindsay C Kobayashi, Andrew Steptoe
OBJECTIVE: To investigate the relationships between social isolation, health literacy, and all-cause mortality, and the modifying effect of social isolation on the latter relationship. METHODS: Data were from 7731 adults aged ≥50 years participating in Wave 2 (2004/2005) of the English Longitudinal Study of Ageing. Social isolation was defined according to marital/cohabiting status and contact with children, relatives, and friends, and participation in social organizations...
November 27, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29168777/association-of-emotional-labor-and-occupational-stressors-with-depressive-symptoms-among-women-sales-workers-at-a-clothing-shopping-mall-in-the-republic-of-korea-a-cross-sectional-study
#14
Yuh-Jin Chung, Woo-Chul Jung, Hyunjoo Kim, Seong-Sik Cho
In the distribution service industry, sales people often experience multiple occupational stressors such as excessive emotional labor, workplace mistreatment, and job insecurity. The present study aimed to explore the associations of these stressors with depressive symptoms among women sales workers at a clothing shopping mall in Korea. A cross sectional study was conducted on 583 women who consist of clothing sales workers and manual workers using a structured questionnaire to assess demographic factors, occupational stressors, and depressive symptoms...
November 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29165629/morbidity-mortality-and-socioeconomics-in-females-with-46-xy-disorders-of-sex-development-a-nationwide-study
#15
Agnethe Berglund, Trine H Johannsen, Kirstine Stochholm, Mette H Viuff, Jens Fedder, Katharina M Main, Claus H Gravholt
Context: Little is known about long-term health outcomes in phenotypic females with 46,XY disorders of sex development (XY females) and the socioeconomic profile is not described in detail. Objective: To describe morbidity, mortality and socioeconomic status in XY females in a comparison to the general population. Design: A nationwide registry study with complete follow-up. Setting: A uniform public health care system...
November 20, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29164961/disability-and-activity-related-emotion-in-later-life-are-effects-buffered-by-intimate-relationship-support-and-strain
#16
Deborah Carr, Jennifer C Cornman, Vicki A Freedman
We use daily diary data from the Disability and Use of Time supplement to the 2013 Panel Study of Income Dynamics ( n = 1,162) to evaluate (1) the extent to which marital/partner support and strain moderate the effects of disability on five activity-related emotions (happiness, calm, sadness, frustration, worry) and overall negative and positive emotion among older married, cohabiting, and dating persons and (2) whether such patterns differ significantly by gender. Marital support buffers against negative emotions and increases feelings of calm among severely impaired women...
September 2017: Journal of Health and Social Behavior
https://www.readbyqxmd.com/read/29164498/gender-and-the-stability-of-same-sex-and-different-sex-relationships-among-young-adults
#17
Kara Joyner, Wendy Manning, Ryan Bogle
Most research on the stability of adult relationships has focused on coresidential (cohabiting or married) unions and estimates rates of dissolution for the period of coresidence. Studies examining how the stability of coresidential unions differs by sex composition have typically found that same-sex female couples have higher rates of dissolution than same-sex male couples and different-sex couples. We argue that the more elevated rates of dissolution for same-sex female couples are a by-product of the focus on coresidential unions...
November 21, 2017: Demography
https://www.readbyqxmd.com/read/29160221/evaluation-of-blue-mussel-mytilus-edulis-as-vector-for-viral-hemorrhagic-septicemia-virus-vhsv
#18
Kwang Il Kim, Young Chul Kim, Woo Ju Kwon, Hyun Do Jeong
When viral diseases occur in aquaculture farms, the virus released into the seawater from infected animals can re-infect other susceptible species or accumulate in filter-feeding organisms. We conducted a viral hemorrhagic septicemia virus (VHSV) survivability analysis of blue mussel Mytilus edulis digestive enzymes, viral depuration, and infectivity tests via in vitro and in vivo inoculation to evaluate the infectious state. VHSV particles were not completely digested within 24 h in vitro and were maintained for 7 d in the mussel digestive gland...
November 21, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/29160194/social-determinants-of-low-fertility-in-brazil
#19
Helena Cruz Castanheira, Hans-Peter Kohler
An increasing number of developing countries are experiencing below replacement fertility rates. Although the factors associated with low fertility in developed countries have been widely explored in the literature, studies of low fertility in middle- and low-income countries continue to be rare. To help fill this gap, Brazil was used as a case study to assess whether human development, gender equality and the ability of mothers with young children to work are associated with the likelihood of married or cohabiting women to have a child...
November 2017: Journal of Biosocial Science
https://www.readbyqxmd.com/read/29154271/does-fatty-acid-composition-in%C3%A2-subcutaneous-adipose-tissue-differ-between-patients-with-alzheimer-s-disease-and-cohabiting-proxies
#20
Gerd Faxen-Irving, Farshad Falahati, Hans Basun, Maria Eriksdotter, Inger Vedin, Lars-Olof Wahlund, Marianne Schultzberg, Erik Hjorth, Jan Palmblad, Tommy Cederholm, Yvonne Freund-Levi
Low tissue levels of the major marine ω3 fatty acids (FAs) DHA and EPA are found in Alzheimer's disease (AD). We investigated if healthy proxies to AD patients have higher levels of these ω3 FAs. We observed lower levels of EPA and DHA in subcutaneous adipose tissue biopsies from 64 AD patients compared with 16 cognitively healthy proxies. No significant difference was observed when pairwise comparisons were made between a subset of 16 AD patients and their co-habiting proxies. Larger studies are needed to replicate these findings and to determine if they could depend on FA intake or differences in metabolism...
November 14, 2017: Journal of Alzheimer's Disease: JAD
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