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Malignant ascitis

Carlo Gobitti, Alessandro Sindoni, Chiara Bampo, Tanja Baresic, Giorgio Giorda, Lara Alessandrini, Vincenzo Canzonieri, Giovanni Franchin, Eugenio Borsatti
Struma ovarii (SO), a rare tumor containing at least 50% of thyroid tissue, represents approximately 5% of all ovarian teratomas; its malignant transformation rate is reported to occur in up to 10% of cases and metastases occur in about 5-6% of them. We describe a 36-year old woman who underwent laparoscopic left annessectomy two years earlier because of an ovarian cyst. Follow-up imaging revealed a right adnexal mass, ascitis and peritoneal nodes that were diagnosed as comprising a malignant SO with peritoneal secondary localizations at histopathology performed after intervention...
July 2017: Hormones: International Journal of Endocrinology and Metabolism
Sweta Singh, Monalisha Naik, Narbadyswari Deep Bag, Susama Patra
Uterine angioleiomyoma is rare. A 40-year-old nulliparous woman presented with heavy menstrual bleeding (HMB) for the past 2 years and mass per abdomen with severe dysmenorrhea for three cycles. She had received 8 units of packed cell transfusion outside. Clinical examination revealed a huge 32-week-sized abdominopelvic mass with irregular margins. Ultrasonography (USG) of the abdomen and pelvis showed a large solid cystic mass on the right side of the abdomen with a well-defined hypoechoeic rounded lesion of size 5...
July 2017: Journal of Mid-life Health
Mi Yeon Nam, Mi Young Kim, Yeo Ju Kim, Chang Hae Suh, Young Chae Chu, Dae Hyung Lee, Jae Sung Cho
OBJECTIVE: To evaluate the computed tomography (CT) findings compared with pathologic features and to determine whether CT findings are useful for diagnosis of appendiceal metastasis in patients with underlying malignancy. MATERIALS AND METHODS: Preoperative CT examinations of 59 patients who had underlying malignancy and underwent appendectomy were evaluated. Appendiceal metastasis (n = 21) and nonmetastasis (n = 38) were pathologically confirmed. Computed tomography features (appendiceal morphology and diameter, presence of ascites, rectal shelf, omental cake, lymphadenopathy or organ metastasis) were retrospectively reviewed, and compared with histopathological findings...
January 2017: Journal of Computer Assisted Tomography
D Serban, C Branescu, C Savlovschi, A El-Khatib, C Tudor, A Nica, A Kraft, A M Dascalu
We present the case of a 52-year-old male patient, hospitalized on an emergency basis in the University Emergency Hospital in Bucharest, after being diagnosed with pneumoperitoneum acute abdomen, for which emergency surgery was mandatory. A 3,5-4 cm malignant gastric perforation, ascitis and peritoneal carcinomatosis were found. The histopathological exam revealed infiltrative mucinous gastric carcinoma with epiploic metastasis. Due to the lack of available gastric material, an atypical surgical solution was performed: gastric packing with epiploic material by means of transgastric traction...
April 2016: Journal of Medicine and Life
Isha Sood, Gaurav M Kasundra, Prathibha Shankaranarayana Supriya, Aradhana Gupta, Bharat Bhushan
A 50-year-old female presented with fever, symmetrical arthralgias, rash, painful oral ulcerations and alopecia since 8 weeks. Examination showed mild hepatospleenomegaly. Investigations revealed leucocytosis, neutrophilia, elevated sedimentation rate and raised ferritin levels (3850 ng/ml). Computerized tomography (CT) abdomen showed hepatospleenomegaly, mild ascitis and mild bilateral pleural-effusion. After ruling out occult infections, tuberculosis, malignancies and autoimmune diseases by appropriate investigations, and due to raised ferritin levels, adult onset stills disease (AOSD) was diagnosed...
July 2015: Journal of Mid-life Health
Jaume Trapé, Gabriel Gurt, Josefina Franquesa, Jesús Montesinos, Anna Arnau, Maria Sala, Francesc Sant, Esther Casado, Josep Maria Ordeig, Carmen Bergos, Francesc Vida, Pau Sort, Álvaro Isava, Montserrat González, Rafael Molina
BACKGROUND: The usefulness of tumor markers in the differential diagnosis of cancer in patients with ascites remains a matter of controversy. Few studies have reported the measurement of cancer antigen 125 (CA125) and cytokeratin 19 soluble fragments (CYFRA21-1) in ascitic fluid. The aim of the present study was to evaluate the diagnostic accuracy of these tumor markers in the detection of malignant ascites. MATERIALS AND METHODS: We analyzed CA125 and CYFRA21-1 from 143 consecutive undiagnosed patients with ascitis...
October 2015: Anticancer Research
Ricardo González-Arango, Diana Castro-Villabón, Luis E Barrera-Herrera, Mauricio Palau, Paula A Rodríguez-Urrego
Desmoplastic small round cell tumor (DSRCT) is a malignant neoplasm that most often presents in male adolescents as an abdominal mass. Cytological features have been previously described, but only two reports noted post chemotherapy changes on effusions. We report a case of a 15-year-old male with DSRCT status postchemotherapy that presented with ascitis. Unusual morphology was seen: Numerous malignant large and single cells with prominent nucleoli and abundant cytoplasm in a background without the stroma, occasional mitosis, and the abundant apoptosis...
January 2015: Journal of Cytology
Nidhi Verma, Suresh Babu, Jitendra Kumar Kushwaha, Atin Singhai
Metastasis of colorectal carcinoma to testis is rare. The authors report a case of 35-year-old man with right testicular mass. Contrast-enhanced CT scan (CECT) of testes showed testicular mass with ascitis and enlargement of retroperitoneal lymphnodes. Thus, a provisional diagnosis of disseminated primary testicular tumour was made. On subsequent high orchidectomy pathological examination revealed mucinous adenocarcinoma with CDX2 positivity thereby suggesting the possibility of metastasis from adenocarcinoma...
2013: BMJ Case Reports
Elena Beortegui Urdánoz, Cristina G Vivar, Navidad Canga Armayor, Cristina Oroviogoicechea Ortega, Anan Canga Armayor, Sagrario Ibarrola Izura
INTRODUCTION: Social and political changes have created an increased in the demand of health care enabling the emergence of diverse professional profiles under the term Advanced Practice Nurse (APN). The APN is a nurse who has acquired a basis of expert knowledge, skills for decision making, and clinical competencies for an extended practice. In Spain, due to the Bologna process and the changes within university, such as postgraduate training, these profiles have begun to emerge. OBJECTIVE: To describe the experience on the implementation of the advanced clinical nursing role in an inpatient oncology unit...
December 2012: Revista de Enfermería
Jerome Rebollos Barrera, Leonido Andrade Manalo, Frances Lina Lantion Ang
Malignant transformation of benign monodermal teratoma is a rare presentation of struma ovarii. A 41-year-old Filipina presented with 1-year history of recurrent lower abdominal pain, abdominal swelling and vomiting. Ultrasound of the abdomen revealed a large cystic abdomino-pelvic mass densely adherent to the intestinal and uterine wall with moderate ascitis. The patient underwent total abdominal hysterectomy and bilateral salphingo-oophorectomy and histopathology showed papillary thyroid-type carcinoma arising from the left struma ovarii...
2012: BMJ Case Reports
Inas Babic, Maha Tulbah, Samir Ghourab
INTRODUCTION: Chyloascites or chyloperitoneum, which can be caused by different factors, is a process of eruption of one or many lymphatic vessels spontaneously. Malignant processes, inflammation or trauma can cause a sudden burst in a lymphatic vessel which will lead to a collection of milky fluid in any space of the human body with the abdominal cavity being the most common location. Chyloperitoneum is rare during pregnancy and this case is the fifth described worldwide. CASE PRESENTATION: We describe a case of chyloascitis in a 27-year-old primigravida Middle Eastern woman, found coincidentally during cesarean section...
2012: Journal of Medical Case Reports
Orestis Ioannidis, Angeliki Cheva, George Paraskevas, Nikolaos Papadimitriou, Athina Konstantara, Stavros Chatzopoulos, Anastasios Kotronis, Apostolos Makrantonakis, Emmanouil Kakoutis
Pseudomyxoma peritonei is a rare clinical condition that is characterized by the presence of mucinous ascitis. It is believed to originate predominately from a mucinous neoplasm of the appendix including a heterogeneous group of tumours ranging from indolentto malignant. It was first described in the late 19th century. Pseudomyxoma retroperitonei is extremely rare with only 33 cases having been reported since the first description in the middle of the 20th century. We report two additional cases of pseudomyxoma retroperitonei and present a review of the literature...
May 2012: Revista Española de Enfermedades Digestivas
Arturo Novoa-Vargas, Karla Sánchez-Bautista, Ismael Coudillo-Luna
The arrenoblastome is an ovary tumor with masculine hormone production, testosterone and other hormones. Other names are: stromatic tumor or gonadal stromatic tumor, also steroid cell tumor. They are rare tumors; represent 0.5% of all ovary tumors. It could be present in all age women groups, more frequently in young people. Most of times unilateral (95%), solids or quistic-solids. Anaplastic grade give them a malignity disease in 5 to 10 % cases. We report the case of a 35 year-old woman with clinical appearance of androgenism for ovary tumor, she was accepted for surgery, founded 7 liters of ascitis, produced for an ovary tumor, integral capsule, it produced masculine hormones...
January 2011: Ginecología y Obstetricia de México
Masahiko Sugiyama, Yoshihiro Kakeji, Shunichi Tsujitani, Yui Harada, Mitsuho Onimaru, Kumi Yoshida, Sakura Tanaka, Yasunori Emi, Masaru Morita, Yosuke Morodomi, Mamoru Hasegawa, Yoshihiko Maehara, Yoshikazu Yonemitsu
Malignant ascitis (MA) is a highly intractable and immunotherapy-resistant state of advanced gastrointestinal and ovarian cancers. Using a murine model of MA with CT26 colon cancer cells, we here determined that the imbalance between the VEGF-A/vascular permeability factor and its decoy receptor, soluble fms-like tryrosine kinase receptor-1 (sFLT-1), was a major cause of MA resistance to dendritic cell (DC)-based immunotherapy. We found that the ratio of VEGF-A/sFLT-1 was increased not only in murine but also in human MA, and F-gene-deleted recombinant Sendai virus (rSeV/dF)-mediated secretion of human sFLT-1 by DCs augmented not only the activity of DCs themselves, but also dramatically improved the survival of tumor-bearing animals associated with enhanced CTL activity and its infiltration to peritoneal tumors...
March 2011: Molecular Cancer Therapeutics
Sebastian Feuerlein, Jochen Stolz, Rainer Muche, Martin Hetzel, Oliver Klass, Hans-Juergen Brambs, Sandra Pauls
UNLABELLED: The purpose of this study was to investigate the potential correlation between the presence and size of the cisterna chyli (CC) on computed tomography (CT) and the presence of cardiovascular disease. MATERIALS AND METHODS: Out of a 3000-patient cohort 2599 patients who received a CT examination of the chest and/or abdomen with measurable inferior vena cava and azygos vein were included in this retrospective study. To assess the presence of cardiovascular disease the following parameters were recorded from the PACS or clinical information system: diameter of vena cava and azygos vein, presence of ascitis, serum creatinine, history of congestive heart failure, coronary artery disease or arterial hypertension and medication (diuretics, beta-blocker)...
August 2011: European Journal of Radiology
Faizollah Safarpor, Menochehr Aghajanzade, Mohammad Reza R Kohsari, Saba Hoda, Ali Sarshad, Delaram Safarpor
BACKGROUND: Tuberculosis continues to be a common disease in Iran and one of its presentations is abdominal tuberculosis. Histopathological confirmation of abdominal tuberculosis is difficult because of suboptional, noninvasive access to the pathology. Laparoscopy provides minimally invasive access to the peritoneum. AIM: The aim is to evaluate the role and importance of laparoscopy in the diagnosis of tuberculous peritonitis (TP). MATERIALS AND METHODS: A retrospective study on laparoscopy in Razi hospital of Rasht (in northern Iran) over a period of ten years showed that diagnostic laparoscopy was performed in 290 patients with abdominal pain, with or without ascites...
July 2007: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
Ludovic Martinet, Rémy Poupot, Pejman Mirshahi, Arash Rafii, Jean-Jacques Fournié, Massoud Mirshahi, Mary Poupot
With metastatic disease at diagnosis for 70% of patients, ovarian cancer represents the most lethal gynecological malignancy. Ovarian carcinomas are aggressive malignancies that can evade immune surveillance and frequently develop into metastases. The tumor microenvironment is decisive for preventing immune attack but, in the case of ovarian carcinoma, the mechanisms are unclear. We recently isolated a novel type of stromal cell from the ascitis of patients with ovarian carcinoma that interacts with epithelial ovarian cancers conferring them chemoresistance...
May 1, 2010: International Journal of Cancer. Journal International du Cancer
E Chouillard
Combining cytoreductive surgery (CRS) and intraperitoneal chemohyperthermia (IPCH) is the most promising new treatment for peritoneal carcinomatosis (PC) from colorectal cancer or from gastric cancer. It is not indicated for all patients with PC, and the results achieved by international experts in this field might not be replicated in routine clinical practice. Patients with good performance status, a low volume of peritoneal disease, and no extra-abdominal metastases are more likely to benefit from the combined treatment...
December 2008: Minerva Chirurgica
Daniel Ginat, Wael E A Saad
Percutaneous cholecystostomy represents a minimally invasive procedure for providing gallbladder decompression, often in critically ill patient populations. Indications for this procedure include calculous and acalculous cholecystitis, gallbladder perforation, malignant obstruction, percutaneous biliary stone removal, biliary duct drainage, and diagnostic imaging of the gallbladder and biliary ductal system. In addition, gallbladder access provided by percutaneous cholecystostomy may serve to carry additional procedures, such as cholangiograms, gallstone dissolution, and lithotripsy...
March 2008: Techniques in Vascular and Interventional Radiology
Nandini Hazarika, B Dhabhar, T K Saikia
BACKGROUND: Cancer antigen 125 (CA 125), a widely used tumor marker for monitoring epithelial ovarian cancer, is also found to be raised in non-gynecological tumors and non malignant disease involving peritoneum. We report a case of non-Hodgkin's lymphoma who presented with peritoneal and pleural effusions with a very high level of serum CA 125. CASE: Fifty four years female presented with gross ascitis, bilateral moderate pleural effusions, right retroperitoneal mass and a very high serum CA 125 level (4462...
January 2008: Journal of the Association of Physicians of India
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