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Spine surgery metastasis

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https://www.readbyqxmd.com/read/29208438/an-integrated-multidisciplinary-algorithm-for-the-management-of-spinal-metastases-an-international-spine-oncology-consortium-report
#1
REVIEW
Daniel E Spratt, Whitney H Beeler, Fabio Y de Moraes, Laurence D Rhines, Joseph J Gemmete, Neeraj Chaudhary, David B Shultz, Sean R Smith, Alejandro Berlin, Max Dahele, Ben J Slotman, Kelly C Younge, Mark Bilsky, Paul Park, Nicholas J Szerlip
Spinal metastases are becoming increasingly common because patients with metastatic disease are living longer. The close proximity of the spinal cord to the vertebral column limits many conventional therapeutic options that can otherwise be used to treat cancer. In response to this problem, an innovative multidisciplinary approach has been developed for the management of spinal metastases, leveraging the capabilities of image-guided stereotactic radiosurgery, separation surgery, vertebroplasty, and minimally invasive local ablative approaches...
December 2017: Lancet Oncology
https://www.readbyqxmd.com/read/29189958/surgical-treatment-of-spinal-metastases-from-renal-cell-carcinoma-effects-of-preoperative-embolization-on-intraoperative-blood-loss
#2
Matthias Reitz, Klaus Christian Mende, Christopher Cramer, Theresa Krätzig, ZSuzsanna Nagy, Eik Vettorazzi, Sven Oliver Eicker, Marc Dreimann
The objective of this paper is analyzing the effects of preoperative embolization on intraoperative blood loss in spinal surgery for renal cell carcinoma (RCC) metastasis and identifying factors contributing to an increased blood loss in the surgical procedure. A retrospective analysis was performed in patients who were treated in for spinal metastasis from RCC between 2011 and 2016. Factors analyzed were reduction of tumor blush, timing of embolization, selective vs. superselective approach, surgical factors, and tumor volume and localization...
November 30, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/29187703/paraganglioma-as-a-risk-factor-for-bone-metastasis
#3
Maki Yokomoto-Umakoshi, Hironobu Umakoshi, Mika Tsuiki, Tatsuki Ogasawara, Kaho Hamanaka-Hiroshima, Akiyo Tanabe, Tetsuya Tagami, Akira Shimatsu, Mitsuhide Naruse
Malignant pheochromocytoma (PHEO) and paraganglioma (PGL) (PHEO and PGL: PPGL) are frequently associated with bone metastasis. Bone metastasis requires long-term management and may lead to skeletal-related events (SREs) that remarkably reduce patients' quality of life (QOL). The aim of this study was to elucidate the risk factors for developing bone metastasis in patients with PPGL. The medical records of 40 consecutive adult patients with malignant PPGL at the National Hospital Organization Kyoto Medical Center between 2006 and 2016 were reviewed...
November 29, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29178305/en-bloc-resection-with-the-assistance-of-video-assisted-thoracoscopy-for-left-lower-lung-cancer-invading-thoracic-vertebrae-and-rib-a-case-report
#4
Yun Liang, Peng Liu, Xiao-Gang Zhou, Xi-Lei Li, Hong Lin, Nong Chen, Di Ge, Jian Dong
Lung cancer invading the spine was previously considered unresectable and fatal and, consequently, there are few reports focusing on tumors located in the lower lung lobe and invading the spine. With the development of spinal instrumentation and surgical techniques, and wider acceptance of spondylectomy by surgeons, radical surgical resection has become feasible. Here, we present a case of a male patient with a left lower lung cancer invading thoracic vertebrae who underwent complete resection with sagittal en bloc hemivertebrectomy with video-assisted thoracoscopy...
November 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29175570/reliability-of-the-tokuhashi-score-to-predict-prognosis-comparison-of-117-patients
#5
Leandro Pelegrini de Almeida, Tamara Vidaletti, André Martins de Lima Cecchini, Ericson Sfreddo, Felipe Martins de Lima Cecchini, Asdrubal Falavigna
BACKGROUND: Spinal metastatic disease compromises the quality of life and prognosis of the patients. Prognosis is an important factor for the decision-making process and needs to be precise in order to adjust the intensity of therapy. The Tokuhashi score is a universal instrument to determine the prognosis. The objective was to analyze the effectiveness of the Tokuhashi score in determining the prognosis of the patients with spine metastasis by comparing the expected survival time from the Tokuhashi score with the survival time observed among surgical patients...
November 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29165794/leptomeningeal-metastasis-from-systemic-cancer-review-and-update-on-management
#6
REVIEW
Nancy Wang, Mia S Bertalan, Priscilla K Brastianos
Leptomeningeal metastasis is an uncommon and typically late complication of cancer with a poor prognosis and limited treatment options. Diagnosis is often challenging, with nonspecific presenting symptoms ranging from headache and confusion to focal neurologic deficits, such as cranial nerve palsies. Standard diagnostic evaluation involves a neurologic examination, magnetic resonance imaging of the brain and spine with gadolinium, and cytologic evaluation of the cerebral spinal fluid. Therapy entails a multimodal approach focused on palliation with surgery, radiation, and/or chemotherapy, which may be administered systemically or directly into the cerebral spinal fluid...
November 22, 2017: Cancer
https://www.readbyqxmd.com/read/29143901/combined-vertebral-augmentation-and-radiofrequency-ablation-in-the-management-of-spinal-metastases-an-update
#7
REVIEW
Ning Mao Kam, Julian Maingard, Hong Kuan Kok, Dinesh Ranatunga, Duncan Brooks, William C Torreggiani, Peter L Munk, Michael J Lee, Ronil V Chandra, Hamed Asadi
Spinal metastases are the most commonly encountered tumour of the spine, occurring in up to 40% of patients with cancer. Each year, approximately 5% of cancer patients will develop spinal metastases. This number is expected to increase as the life expectancy of cancer patients increases. Patients with spinal metastases experience severe and frequently debilitating pain, which often decreases their remaining quality of life. With a median survival of less than 1 year, the goals of treatment in spinal metastases are reducing pain, improving or maintaining level of function and providing mechanical stability...
November 16, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29138702/a-case-of-c5-vertebral-chordoma-in-a-73-year-old-patient-with-more-than-8-years-of-follow-up-after-total-piecemeal-spondylectomy
#8
Keigo Tanaka, Harutoshi Sakakima, Kazutoshi Hida, Kanako Hatanaka, Kosei Ijiri
Chordoma arising from the cervical spine is rare and the traditional long-term prognosis is typically poor. Total en bloc spondylectomy with a wide margin is generally accepted to be the most appropriate management for thoracic and lumbar malignant tumors. However, this method is still challenging for the cervical spine because of the proximity of the tumor to the vertebral arteries and neural elements. Here, we report a 73-year-old man with a C5 vertebral chordoma treated with total piecemeal spondylectomy...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29125427/the-surgical-treatment-of-metastatic-spine-tumors-within-the-intramedullary-compartment
#9
Ben A Strickland, Ian E McCutcheon, Indro Chakrabarti, Laurence D Rhines, Jeffrey S Weinberg
OBJECTIVE Metastasis to the spinal cord is rare, and optimal management of this disease is unclear. The authors investigated this issue by analyzing the results of surgical treatment of spinal intramedullary metastasis (IM) at a major cancer center. METHODS The authors retrospectively reviewed the medical records of 13 patients who underwent surgery for IM. Patients had renal cell carcinoma (n = 4), breast carcinoma (n = 3), melanoma (n = 2), non-small cell lung cancer (n = 1), sarcoma (n = 1), adenoid cystic carcinoma (n = 1), and cervical cancer (n = 1)...
November 10, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29124954/practicality-of-using-the-figure-of-eight-bandage-to-prevent-fatal-wound-dehiscence-after-spinal-tumor-surgery-for-upper-thoracic-metastasis
#10
Dong Kwang Seo, Jin-Hoon Park, Sun Kyu Oh, Yongchel Ahn, Sang Ryong Jeon
OBJECT: Serious postoperative wound problems can frequently develop after surgery with perioperative RT for upper thoracic metastatic lesions. The figure-of-eight bandage can restrict excessive shoulder motion, which could prevent wound dehiscence. The purpose of this study was to describe the efficacy of using the figure-of-eight bandage to prevent postoperative wound dehiscence. METHODS: Between February 2005 and July 2015, we retrospectively evaluated the medical records of cancer patients who underwent surgery with or without RT for spinal metastasis involving the upper thoracic spine...
November 10, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29071122/diagnostic-algorithm-prognostic-factors-and-surgical-treatment-of-metastatic-cancer-diseases-of-the-long-bones-and-spine
#11
REVIEW
Miklós Szendrői, Imre Antal, Attila Szendrői, Áron Lazáry, Péter Pál Varga
Oncological management of skeletal metastases has changed dramatically in the last few decades. A significant number of patients survive for many years with their metastases.Surgeons are more active and the technical repertoire is broader, from plates to intramedullary devices to (tumour) endoprostheses.The philosophy of treatment should be different in the case of a trauma-related fracture and a pathological fracture. A proper algorithm for establishing a diagnosis and evaluation of prognostic factors helps in planning the surgical intervention...
September 2017: EFORT open reviews
https://www.readbyqxmd.com/read/29031992/assessing-the-utility-of-a-prognostication-model-to-predict-1-year-mortality-in-patients-undergoing-radiation-therapy-for-spinal-metastases
#12
Diana D Shi, Yu-Hui Chen, Tai Chung Lam, Dana Leonard, Tracy Anne Balboni, Andrew Schoenfeld, Sonia Skamene, Daniel N Cagney, John H Chi, Charles H Cho, Mitchel Harris, Marco L Ferrone, Lauren M Hertan
BACKGROUND CONTEXT: Predicting survival outcomes after radiation therapy (RT) alone for metastatic disease of the spine is a challenging task that is important to guiding treatment decisions (eg, determining dose fractionation and intensity). The New England Spinal Metastasis Score (NESMS) was recently introduced and validated in independent cohorts as a tool to predict 1-year survival following surgery for spinal metastases. This metric is composed of three factors: preoperative albumin, ambulatory status, and modified Bauer score, with the total score ranging from 0 to 3...
October 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28993889/recurrent-primary-osseous-hemangiopericytoma-in-the-thoracic-spine-a-case-report-and-literature-review
#13
Takahiro Onoki, Haruo Kanno, Toshimi Aizawa, Ko Hashimoto, Eiji Itoi, Hiroshi Ozawa
PURPOSE: Primary osseous hemangiopericytoma (HPC) of the spine is exceedingly rare. HPC has malignant potential and has the capacity for metastasis and local recurrence. We herein present the first case of recurrent primary osseous HPC in the thoracic spine that was successfully treated by total spondylectomy at three vertebral levels and spinal reconstruction. METHODS: We performed a two-stage operation for recurrent HPC using anterior and posterior approaches at the T5-T7 vertebrae...
October 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28904580/extradural-spinal-metastasis-in-ovarian-mixed-germ-cell-tumor
#14
Deepashu Sachdeva, Vikas Kumar, Ravindra Kumar Saran, Arvind Kumar Srivastava
Ovarian germ cell tumors (GCTs) are rare and affect mainly young girls and women. Two histological groups are distinguished: dysgerminomas and nondysgerminomatous tumors. These tumors have initial good responses to surgery and chemotherapy in 80% cases, but >75% of patients die due to complications of disease progression. There are very few case reports of mixed GCT with extradural spine metastases. We report a rare case of a 17-year-old girl who had undergone left salpingo-oophorectomy with omental and peritoneal biopsy for ovarian GCT with extradural spinal metastasis...
April 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28868202/a-thoracic-vertebral-localization-of-a-metastasized-cutaneous-merkel-cell-carcinoma-case-report-and-review-of-literature
#15
Rosario Maugeri, Antonella Giugno, Roberto G Giammalva, Carlo Gulì, Luigi Basile, Francesca Graziano, Domenico G Iacopino
BACKGROUND: Merkel cell carcinoma (MCC) is a rare neuroendocrine skin tumor, which may be related to sun exposure. It can metastasize to lungs, liver and bone, leading to severe morbidity and mortality. Vertebral metastases from MCC are rare. The authors report the tenth case in the literature, a 59-year-old patient with MCC, which was primarily localized in the scalp, and later provoked distant metastasis to the thoracic spinal column. CASE DESCRIPTION: A 59-year-old woman was admitted at our Unit of Neurosurgery with a 4-month history of progressive and severe dorsal back pain, without neurological signs...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28830484/oncological-and-functional-results-of-the-surgical-treatment-of-vertebral-metastases-in-patients-with-multiple-myeloma
#16
Grzegorz Guzik
BACKGROUND: In nearly 30% of patients with myeloma, pathological fractures are found to occur in the spine. If the patients are not treated promptly and satisfactorily, the quality of their lives diminishes. Currently, the standard treatment for metastatic lesions of the spine is radiotherapy, but surgical intervention is becoming more frequent. It is very important to quickly identify metastases and implement surgical treatment before any fracture/s occur. METHODS: Over the period of 2010-2014 in our department, a total of 129 patients were treated for metastatic spinal myeloma...
August 23, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28819870/surgical-complications-of-extraspinal-tumors-in-the-cervical-spine-a-report-of-110-cases-and-literature-review
#17
WenHua Yang, Liang Jiang, XiaoGuang Liu, Feng Wei, Miao Yu, FengLiang Wu, Lei Dang, Hua Zhou, Hua Zhang, ZhongJun Liu
PURPOSE: To assess the safety of surgical intervention for extraspinal tumors in the cervical spine. METHODS: 110 consecutive patients were enrolled and followed-up at least 12 months or until death. The complication rates and risk factors were documented and analyzed. RESULTS: The quality of life in the surviving patients was significantly improved. The overall local recurrence rate was 17.3%. Twenty percent of patients developed distant metastasis...
August 17, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28807628/vertebral-alveolar-echinococcosis-a-case-report-systematic-analysis-and-review-of-the-literature
#18
REVIEW
Thomas Raphael Meinel, Bruno Gottstein, Vanessa Geib, Marius Johann Keel, Ruggero Biral, Markus Mohaupt, Jan Brügger
Alveolar echinococcosis caused by Echinococcus multilocularis is an infrequent zoonosis with a high degree of disability, morbidity, and mortality, especially in disease clusters of the northern hemisphere. The diagnosis is complicated by extended incubation time, diverse clinical manifestations, and mimicking of differential diagnoses. The primary organ affected is the liver, but extrahepatic disease is possible, with vertebral involvement in only a few dozen cases described worldwide. Although vertebral alveolar echinococcosis seems to be rare, it might be under diagnosed, and it might be seen more often as the number of people with immunocompromised conditions increases...
August 11, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28740742/radical-surgery-of-only-the-anterior-elements-of-the-spine-at-the-posterior-element-fusion-level-due-to-metastatic-thyroid-cancer
#19
Ryuto Tsuchiya, Kazuki Fujimoto, Kazuhide Inage, Sumihisa Orita, Yasuhiro Shiga, Hiroto Kamoda, Kazuyo Yamauchi, Miyako Suzuki, Jun Sato, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Masao Koda, Takeo Furuya, Junichi Nakamura, Kazuhisa Takahashi, Seiji Ohtori
Spinal metastasis of differentiated thyroid cancer can have a favorable prognosis if radical surgery is performed. We encountered a case of spinal metastasis involving three anterior vertebral bodies at the posterior element fusion level and successfully achieved adequate stability by radical surgery involving only the anterior elements. A 67-year-old woman who had numbness and muscle weakness in the lower limbs caused by metastatic spinal tumor at the posterior element fusion level of L1-L3 vertebrae was treated with radical surgery of only the anterior element to gain stability...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28674582/intramedullary-spinal-cord-metastasis-from-laryngeal-carcinoma-case-report-and-review-of-literature
#20
REVIEW
Mohamed Sahli, Bouchaib Hemmaoui, Fouad Benariba
Laryngeal cancer metastases are relatively rare and mainly affect the lung. The medullary localization remains exceptional. We report the case of a patient followed for operated laryngeal cancer and whose oncologic control revealed a medullary localization. A patient followed for squamous cell carcinoma of the larynx, treated in 2010 by a partial surgery whose endoscopic control at 5 years revealed the presence of right arytenoid edema without suspicious lesions, multiple biopsies were made and which returned negative...
2017: Pan African Medical Journal
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