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Spine surgery metastasis

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https://www.readbyqxmd.com/read/29910637/combined-microwave-ablation-and-minimally-invasive-open-decompression-for-the-management-of-thoracic-metastasis-in-breast-cancer
#1
Bin Liu, Zhenchao Yuan, Chang Yuan Wei
Objective: The incidence rate of thoracic metastasis from breast cancer is increasing. Microwave ablation is one type of clinical therapy used to treat metastatic spine disease, although it can cause protein denaturation and immediate cell death, and coagulative necrosis can occur. Minimally invasive open decompression is associated with lower rates of surgical complications in comparison to traditional open surgery. Therefore, it is an alternative therapeutic option for spinal metastases...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29878714/recurrence-of-giant-cell-tumor-of-the-spine-after-resection-a-report-of-10-cases
#2
Peng Lin, Nong Lin, Wangsiyuan Teng, Sheng-Dong Wang, Wei-Bo Pan, Xin Huang, Xiao-Bo Yan, Meng Liu, Heng-Yuan Li, Bing-Hao Li, Ling-Ling Sun, Zhan Wang, Xing-Zhi Zhou, Zhao-Ming Ye
OBJECTIVE: To review the clinical details and further treatments for recurrent spinal giant cell tumors (SGCT), and to analyze the risk factors of recurrence and shed new light on the treatment options and prognosis of recurrent SGCT. METHODS: A retrospective analysis of recurrent SGCT between April 2003 and January 2014 was performed. A total of 10 patients comprising 3 men and 7 women with a mean age of 28.9 years (range, 21-40 years) were included in the study...
May 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29808457/total-en-bloc-spondylectomy-through-a-posterior-approach-technique-and-surgical-outcome-in-thoracic-metastases
#3
Maurizio Domenicucci, Lorenzo Nigro, Roberto Delfini
BACKGROUND: In 1981, Roy-Camille et al. have firstly reported the total en-bloc spondylectomy (TES) through a posterior approach for cases of malignant spine tumors in order to reduce the local recurrence and to increase the patient's survival. By then, this surgery has been increasingly gaining recognition. However, it requires a high level of technical ability and knowledge of spinal anatomy, physiology, and biomechanics. METHOD: Herein, we report the patient's selection and technique to execute the TES for cases of thoracic metastasis...
July 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29744614/a-case-of-epidural-glioblastoma-metastasis-presenting-with-a-cervical-myelopathy-torticollis-and-l-hermitte-s-phenomenon
#4
Michael W Ruff, Adip G Bhargav, Aditya Raghunathan
Extraneural glioblastoma metastases are exceedingly rare, though previously described in the literature. Activating mutations in the BRAF kinase gene (V600E) are present in a minority of glioblastoma patients. Here, we describe a case of systemic metastases of a clonal subpopulation of BRAF V600E mutated glioblastoma in a patient previously treated with surgery, radiation, temozolomide and bevacizumab. The patient presented with a subacute cervical myelopathy during adjuvant treatment. He underwent emergent surgical decompression of an epidural spine metastasis...
May 9, 2018: Brain Tumor Pathology
https://www.readbyqxmd.com/read/29663145/successful-treatment-of-a-diffuse-type-tenosynovial-giant-cell-tumor-in-the-thoracic-spine-mimicking-spinal-metastasis-by-frozen-recapping-laminoplasty-in-a-patient-with-thyroid-cancer
#5
REVIEW
Noritaka Yonezawa, Hideki Murakami, Satoshi Kato, Hiroyuki Hayashi, Hiroyuki Tsuchiya
PURPOSE: Tenosynovial giant cell tumor of the diffuse type (TGCT-D) involving the spine is rare. Its differential diagnosis includes metastatic disease; however, there have been few reports of spinal TGCT-D mimicking spinal metastasis in patients with a history of malignancy. METHODS: We report on a 35-year-old woman with a history of papillary thyroid cancer who was diagnosed with TGCT-D of the thoracic spine mimicking spinal metastasis. Preoperative computed tomography (CT) revealed a 1...
April 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29649089/prognostic-factors-of-patients-with-malignant-epithelioid-vascular-tumors-in-the-spine-retrospective-analysis-of-46-patients-in-a-single-center
#6
Kehan Xu, Yujie Liu, Bo Li, Jialin Li, Hao Zhang, Yuechao Zhao, Quan Huang, Haifeng Wei, Jianru Xiao
STUDY DESIGN: A retrospective study of 46 patients with malignant epithelioid vascular tumors (MEVT) in the spine was performed. OBJECTIVE: The purpose of this study was to illustrate the clinic characteristics of MEVT in the spine and to discuss prognostic factors by survival analysis. SUMMARY OF BACKGROUND DATE: MEVT in the spine is relatively uncommon, and there is little published information regarding this subject. Therefore, prognostic factors of this disease are still controversial...
April 11, 2018: Spine
https://www.readbyqxmd.com/read/29596214/natural-history-and-prognostic-factors-of-cholangiocarcinoma-with-spinal-metastasis-a-10-year-single-center-study
#7
Apiruk Sangsin, Dew Saiudom, Suthipas Pongmanee, Jirawat Saengsin, Taninnit Leerapun, Hideki Murakami
STUDY DESIGN: This is a retrospective analysis. OBJECTIVE: The aim of this study was to determine the epidemiology, survival, and prognostic factors for cholangiocarcinoma (CCA) with spinal metastasis. SUMMARY OF BACKGROUND DATA: CCA is an epithelial cell malignancy of the bile duct, and a frequent site for its metastasis is the spine. Many areas of Asia are endemic for CCAs. To date, there is limited data on the epidemiology, natural history, and prognostic factors of CCA with spinal metastasis, which is crucial for better management and treatment of the disease...
April 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29581018/application-of-morphometrics-as-a-predictor-for-survival-in-patients-with-prostate-cancer-metastasis-to-the-spine
#8
Hesham Mostafa Zakaria, Lara Massie, Azam Basheer, Erinma Elibe, David Boyce-Fappiano, Lonni Shultz, Ian Lee, Brent Griffith, Farzan Siddiqui, Victor Chang
BACKGROUND: Surgery for spinal metastases can improve survival but has high morbidity that can potentially diminish benefits. New objective methods of predicting overall survival would be beneficial for surgical decision making. Morphometrics quantifies patient frailty and has been successfully used to predict overall survival in patients with lung cancer spinal metastases. This study evaluated whether morphometrics can predict survival in patients with prostate cancer spinal metastases...
June 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29567516/predicting-survival-for-metastatic-spine-disease-a-comparison-of-nine-scoring-systems
#9
A Karim Ahmed, C Rory Goodwin, Amir Heravi, Rachel Kim, Nancy Abu-Bonsrah, Eric Sankey, Daniel Kerekes, Rafael De la Garza Ramos, Joseph Schwab, Daniel M Sciubba
BACKGROUND CONTEXT: Despite advances in spinal oncology, research in patient-based prognostic calculators for metastatic spine disease is lacking. Much of the literature in this area investigates the general predictive accuracy of scoring systems in heterogeneous populations, with few studies considering the accuracy of scoring systems based on patient specifics such as type of primary tumor. PURPOSE: The aim of the present study was to compare the ability of widespread scoring systems to estimate both overall survival at various time points and tumor-specific survival for patients undergoing surgical treatment for metastatic spine disease in order to provide surgeons with information to determine the most appropriate scoring system for a specific patient and timeline...
March 19, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29521748/delayed-diagnosis-of-gorlin-goltz-syndrome-the-importance-of-the-multidisciplinary-approach
#10
Jéssica Araújo Figueira, Fábio Roberto de Souza Batista, Karina Rosso, Vanessa Cristina Veltrini, Angelo José Pavan
Gorlin-Goltz syndrome (GGS), also known as nevoid basal cell carcinoma syndrome, is an autosomal dominant inherited disorder with high penetrance and variable expressivity. The classic triad originally described by Gorlin and Goltz in 1960 is composed of multiple nevoid basal cell carcinomas (NBCCs), odontogenic keratocysts (OKCs) in the jaws and bifid ribs. in 1977, this triad was modified by Rayner et al, and to GGS diagnosis, the OKCs had to appear in combination with calcification of the cerebellar falx or palmar and plantar pits...
March 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29355803/full-endoscopic-interlaminar-approach-for-nerve-root-decompression-of-sacral-metastatic-tumor
#11
Sheng-Hua Tsai, Hsuan-Han Wu, Chun-Yuan Cheng, Chien-Min Chen
BACKGROUND: Endoscopic surgery has been successfully applied in treatment of degenerative spinal disease, but few studies have assessed its use in treating sacral metastasis. We report a successful full endoscopic interlaminar approach for sacral nerve root decompression of a sacral metastatic tumor. CASE DESCRIPTION: An 80-year-old man with a history of hepatocellular carcinoma presented with buttock pain with radiation to the right lower leg for 1 week. There was also decreased muscle power of the right lower extremity...
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29354752/primary-leiomyosarcoma-of-the-spine-treated-with-total-en-bloc-spondylectomy-the-first-case-in-thailand-a-case-report-and-literature-review
#12
Tinnakorn Pluemvitayaporn, Chaiwat Piyaskulkaew, Sombat Kunakornsawat, Pritsanai Pruttikul
Leiomyosarcoma is a rare type of malignant soft tissue tumor and also one of the most aggressive soft tissue sarcomas. It commonly occurs in uterus, abdominal viscera, retroperitoneal space and soft tissue of the extremities. Primary osseous leiomyosarcoma is a rare condition. Furthermore, primary leiomyosarcoma of the spine is extremely rare. Only few cases have been reported. However, the treatment and outcomes remains controversial. Therefore, the objective of this case report is to illustrate the management of this extremely rare disease by using total en bloc spondylectomy (TES) procedure, which is one of a suitable option for surgical resection of the spinal tumors...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29349614/treatment-and-outcomes-of-28-patients-with-spinal-metastasis-from-gynecological-cancer
#13
Xin Gao, Chenglong Zhao, Shaohui He, Tianqi Fan, Wei Xu, Cheng Yang, Tielong Liu, Jianru Xiao
The aim of this study was to provide some useful information concerning clinical characteristics, surgical treatment, potential contributing factor and prognostic factors for patients with gynecological cancer (GC) spinal metastasis. We reviewed 28 patients with GC spinal metastasis in our spine tumor center between July 2008 and July 2015. Surgeries were performed on 22 of them. Univariate and multivariate analyses were conducted to identify potential prognostic factors affecting spinal metastasis-free survival (SMFS) and overall survival...
April 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29287022/inflammatory-pseudotumor-like-follicular-dendritic-cell-sarcoma-of-the-spleen-computed-tomography-imaging-characteristics-in-5-patients
#14
Xiumei Li, Zhenshan Shi, Ruixiong You, Yueming Li, Dairong Cao, Renjie Lin, Xinming Huang
OBJECTIVES: The purpose of this study was to retrospectively review the computed tomography (CT) and clinicopathological characteristics of inflammatory pseudotumor (IPT)-like follicular dendritic cell sarcoma (FDCS) of the spleen in 5 patients. METHODS: Clinical, pathologic, and CT imaging findings of 5 patients with IPT-like FDCS of the spleen were reviewed and analyzed. Computed tomography imaging and pathologic features were compared. RESULTS: Abdominal unenhanced CT revealed a well-defined hypodense mass in the spleen with complex internal architecture with focal necrosis and/or speckle-strip calcification...
December 28, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29247908/multimodality-treatment-of-intradural-extramedullary-ewing-s-sarcomas-a-systematic-review
#15
REVIEW
Konstantinos N Paterakis, Alexandros Brotis, Efthimios Dardiotis, Theofanis Giannis, Christos Tzerefos, Kostas N Fountas
Ewing's sarcoma (ES) is an aggressive bone and soft tissue sarcoma that usually affects adolescents and young adults. ES occasionally presents as an intradural-extramedullary lesion of the spine. Our aim was to study the role of the multimodality treatment on the survival (overall survival, recurrence-free survival, and metastasis-free survival) of patients with intradural-extramedullary Ewing's sarcoma. Pubmed, EMBASE, Scopus, Web of Science, Cochrane Reviews were searched up to January 2017, using as mesh terms "intradural extramedullary", "Ewing's sarcoma", AND "treatment"...
January 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29208438/an-integrated-multidisciplinary-algorithm-for-the-management-of-spinal-metastases-an-international-spine-oncology-consortium-report
#16
REVIEW
Daniel E Spratt, Whitney H Beeler, Fabio Y de Moraes, Laurence D Rhines, Joseph J Gemmete, Neeraj Chaudhary, David B Shultz, Sean R Smith, Alejandro Berlin, Max Dahele, Ben J Slotman, Kelly C Younge, Mark Bilsky, Paul Park, Nicholas J Szerlip
Spinal metastases are becoming increasingly common because patients with metastatic disease are living longer. The close proximity of the spinal cord to the vertebral column limits many conventional therapeutic options that can otherwise be used to treat cancer. In response to this problem, an innovative multidisciplinary approach has been developed for the management of spinal metastases, leveraging the capabilities of image-guided stereotactic radiosurgery, separation surgery, vertebroplasty, and minimally invasive local ablative approaches...
December 2017: Lancet Oncology
https://www.readbyqxmd.com/read/29189958/surgical-treatment-of-spinal-metastases-from-renal-cell-carcinoma-effects-of-preoperative-embolization-on-intraoperative-blood-loss
#17
Matthias Reitz, Klaus Christian Mende, Christopher Cramer, Theresa Krätzig, ZSuzsanna Nagy, Eik Vettorazzi, Sven Oliver Eicker, Marc Dreimann
The objective of this paper is analyzing the effects of preoperative embolization on intraoperative blood loss in spinal surgery for renal cell carcinoma (RCC) metastasis and identifying factors contributing to an increased blood loss in the surgical procedure. A retrospective analysis was performed in patients who were treated in for spinal metastasis from RCC between 2011 and 2016. Factors analyzed were reduction of tumor blush, timing of embolization, selective vs. superselective approach, surgical factors, and tumor volume and localization...
November 30, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/29187703/paraganglioma-as-a-risk-factor-for-bone-metastasis
#18
Maki Yokomoto-Umakoshi, Hironobu Umakoshi, Mika Tsuiki, Tatsuki Ogasawara, Kaho Hamanaka-Hiroshima, Akiyo Tanabe, Tetsuya Tagami, Akira Shimatsu, Mitsuhide Naruse
Malignant pheochromocytoma (PHEO) and paraganglioma (PGL) (PHEO and PGL: PPGL) are frequently associated with bone metastasis. Bone metastasis requires long-term management and may lead to skeletal-related events (SREs) that remarkably reduce patients' quality of life (QOL). The aim of this study was to elucidate the risk factors for developing bone metastasis in patients with PPGL. The medical records of 40 consecutive adult patients with malignant PPGL at the National Hospital Organization Kyoto Medical Center between 2006 and 2016 were reviewed...
March 28, 2018: Endocrine Journal
https://www.readbyqxmd.com/read/29178305/en-bloc-resection-with-the-assistance-of-video-assisted-thoracoscopy-for-left-lower-lung-cancer-invading-thoracic-vertebrae-and-rib-a-case-report
#19
Yun Liang, Peng Liu, Xiao-Gang Zhou, Xi-Lei Li, Hong Lin, Nong Chen, Di Ge, Jian Dong
Lung cancer invading the spine was previously considered unresectable and fatal and, consequently, there are few reports focusing on tumors located in the lower lung lobe and invading the spine. With the development of spinal instrumentation and surgical techniques, and wider acceptance of spondylectomy by surgeons, radical surgical resection has become feasible. Here, we present a case of a male patient with a left lower lung cancer invading thoracic vertebrae who underwent complete resection with sagittal en bloc hemivertebrectomy with video-assisted thoracoscopy...
November 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29175570/reliability-of-tokuhashi-score-to-predict-prognosis-comparison-of-117-patients
#20
Leandro Pelegrini de Almeida, Tamara Vidaletti, André Martins de Lima Cecchini, Ericson Sfreddo, Felipe Martins de Lima Cecchini, Asdrubal Falavigna
BACKGROUND: Spinal metastatic disease compromises the quality of life and prognosis of the patients. Prognosis is an important factor for the decision-making process and needs to be precise in order to adjust the intensity of therapy. The Tokuhashi score is a universal instrument to determine the prognosis. The objective was to analyze the effectiveness of the Tokuhashi score in determining the prognosis of the patients with spine metastasis by comparing the expected survival time from the Tokuhashi score with the survival time observed among surgical patients...
March 2018: World Neurosurgery
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