keyword
MENU ▼
Read by QxMD icon Read
search

mott

keyword
https://www.readbyqxmd.com/read/27933519/heterogeneous-stock-populations-for-analysis-of-complex-traits
#1
Leah C Solberg Woods, Richard Mott
Heterogeneous Stock (HS) populations allow for fine-resolution genetic mapping of a variety of complex traits. HS mice and rats were created from breeding together eight inbred strains, followed by maintaining the colony in a manner that minimizes inbreeding. After 50 or more generations of breeding, the resulting animals' chromosomes represent a genetic mosaic of the founders' haplotypes, with the average distance between recombination events in the centiMorgan range. This allows for genetic mapping to only a few Mb, a much smaller region than what can be identified using traditional F2 intercross or backcross mapping strategies...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27922192/evidence-for-pipecolate-oxidase-in-mediating-protection-against-hydrogen-peroxide-stress
#2
Sathish Kumar Natarajan, Ezhumalai Muthukrishnan, Oleh Khalimonchuk, Justin L Mott, Donald F Becker
Pipecolate, an intermediate of the lysine catabolic pathway, is oxidized to Δ(1) -piperideine-6-carboxylate (P6C) by the flavoenzyme L-pipecolate oxidase (PIPOX). P6C spontaneously hydrolyzes to generate α-aminoadipate semialdehyde, which is then converted into α-aminoadipate acid by α-aminoadipatesemialdehyde dehydrogenase. L-pipecolate was previously reported to protect mammalian cells against oxidative stress. Here, we examined whether PIPOX is involved in the mechanism of pipecolate stress protection...
December 6, 2016: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/27910915/locating-the-quantum-critical-point-of-the-bose-hubbard-model-through-singularities-of-simple-observables
#3
Mateusz Łącki, Bogdan Damski, Jakub Zakrzewski
We show that the critical point of the two-dimensional Bose-Hubbard model can be easily found through studies of either on-site atom number fluctuations or the nearest-neighbor two-point correlation function (the expectation value of the tunnelling operator). Our strategy to locate the critical point is based on the observation that the derivatives of these observables with respect to the parameter that drives the superfluid-Mott insulator transition are singular at the critical point in the thermodynamic limit...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27908835/modulation-of-signaling-through-gpcr-camp-pka-pathways-by-pde4-depends-on-stimulus-intensity-possible-implications-for-the-pathogenesis-of-acrodysostosis-without-hormone-resistance
#4
Emmanuelle Motte, Catherine Le Stunff, Claire Briet, Nicolas Dumaz, Caroline Silve
In acrodysostosis without hormone resistance, a disease caused by phosphodiesterase (PDE)-4D mutations, increased PDE activity leads to bone developmental defects but with normal renal responses to PTH. To identify potential mechanisms for these disparate responses, we compared the effect of PDE activity on hormone signaling through the GPCR-Gsα-cAMP-PKA pathway in cells from two lineages, HEK-293 cells stably overexpressing PTH1R (HEKpthr) and human dermal fibroblasts, including studies evaluating cAMP levels using an Epac-based BRET-sensor for cAMP (CAMYEL)...
November 28, 2016: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/27886470/stability-of-high-density-two-dimensional-excitons-against-a-mott-transition-in-high-magnetic-fields-probed-by-coherent-terahertz-spectroscopy
#5
Qi Zhang, Yongrui Wang, Weilu Gao, Zhongqu Long, John D Watson, Michael J Manfra, Alexey Belyanin, Junichiro Kono
We have performed time-resolved terahertz absorption measurements on photoexcited electron-hole pairs in undoped GaAs quantum wells in magnetic fields. We probed both unbound- and bound-carrier responses via cyclotron resonance and intraexciton resonance, respectively. The stability of excitons, monitored as the pair density was systematically increased, was found to dramatically increase with increasing magnetic field. Specifically, the 1s-2p_{-} intraexciton transition at 9 T persisted up to the highest density, whereas the 1s-2p feature at 0 T was quickly replaced by a free-carrier Drude response...
November 11, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27885832/defining-pediatric-inpatient-cardiology-care-delivery-models-a-survey-of-pediatric-cardiology-programs-in-the-usa-and-canada
#6
Antonio R Mott, Steven R Neish, Melissa Challman, Timothy F Feltes
BACKGROUND: The treatment of children with cardiac disease is one of the most prevalent and costly pediatric inpatient conditions. The design of inpatient medical services for children admitted to and discharged from noncritical cardiology care units, however, is undefined. North American Pediatric Cardiology Programs were surveyed to define noncritical cardiac care unit models in current practice. METHOD: An online survey that explored institutional and functional domains for noncritical cardiac care unit was crafted...
November 25, 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/27884112/erratum-to-genetic-analysis-of-intestinal-polyp-development-in-collaborative-cross-mice-carrying-the-apc-min-mutation
#7
Alexandra Dorman, Daria Baer, Ian Tomlinson, Richard Mott, Fuad A Iraqi
No abstract text is available yet for this article.
November 24, 2016: BMC Genetics
https://www.readbyqxmd.com/read/27883049/mqc-a-heuristic-quality-control-metric-for-high-throughput-drug-combination-screening
#8
Lu Chen, Kelli Wilson, Ian Goldlust, Bryan T Mott, Richard Eastman, Mindy I Davis, Xiaohu Zhang, Crystal McKnight, Carleen Klumpp-Thomas, Paul Shinn, John Simmons, Mike Gormally, Sam Michael, Craig J Thomas, Marc Ferrer, Rajarshi Guha
Quality control (QC) metrics are critical in high throughput screening (HTS) platforms to ensure reliability and confidence in assay data and downstream analyses. Most reported HTS QC metrics are designed for plate level or single well level analysis. With the advent of high throughput combination screening there is a need for QC metrics that quantify the quality of combination response matrices. We introduce a predictive, interpretable, matrix-level QC metric, mQC, based on a mix of data-derived and heuristic features...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27878144/characteristics-of-chemical-bonding-of-pentavalent-uranium-in-la-doped-uo2
#9
Sergei M Butorin, Kristina O Kvashnina, Damien Prieur, Murielle Rivenet, Philippe M Martin
The effect of La doping on the electronic structure of U in UO2 was studied using an advanced technique, namely, X-ray absorption spectroscopy (XAS) in the high-energy-resolution fluorescence-detection (HERFD) mode, at the U 3d3/2 (M4) edge. Thanks to a significant reduction of the core-hole lifetime broadening and distinct chemical shifts of the HERFD-XAS lines, the U(v) formation as a result of La doping was identified. The isolated contribution of U(v) in the M4 HERFD-XAS spectrum reveals the so-called charge-transfer satellites due to the U 5f-O 2p hybridization...
November 23, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27875325/phase-diagram-of-interacting-spinless-fermions-on-the-honeycomb-lattice
#10
Sylvain Capponi
Fermions hopping on a hexagonal lattice represent one of the most active research fields in condensed matter since the discovery of graphene in 2004 and its numerous applications. Another exciting aspect of the interplay between geometry and quantum mechanical effects is given by the Haldane model (Haldane 1988 Phys. Rev. Lett. 61 2015), where spinless fermions experiencing a certain flux pattern on the honeycomb lattice leads to the stabilization of a topological phase of matter, distinct from a Mott insulator and nowadays dubbed Chern insulator...
February 1, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27869911/controlled-production-of-sub-millimeter-liquid-core-hydrogel-capsules-for-parallelized-3d-cell-culture
#11
Hugo Doméjean, Mathieu de la Motte Saint Pierre, Anette Funfak, Nicolas Atrux-Tallau, Kevin Alessandri, Pierre Nassoy, Jérôme Bibette, Nicolas Bremond
Liquid core capsules having a hydrogel membrane are becoming a versatile tool for three-dimensional culture of micro-organisms and mammalian cells. Making sub-millimeter capsules at a high rate, via the breakup of a compound jet in air, opens the way to high-throughput screening applications. However, control of the capsule size monodispersity, especially required for quantitative bioassays, was still lacking. Here, we report how the understanding of the underlying hydrodynamic instabilities that occur during the process can lead to calibrated core-shell bioreactors...
November 21, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27863056/3%C3%A2-d-co3-po4-2-reduced-graphene-oxide-flowers-for-photocatalytic-water-splitting-a-type%C3%A2-ii-staggered-heterojunction-system
#12
Alaka Samal, Smrutirekha Swain, Biswarup Satpati, Dipti Prakasini Das, Barada Kanta Mishra
The design, synthesis, and photoelectrochemical characterization of Co3 (PO4 )2 , a hydrogen evolving catalyst modified with reduced graphene oxide (RGO), is reported. The 3 D flowerlike Co3 (PO4 )2 heterojunction system, consisting of 3 D flowerlike Co3 (PO4 )2 and RGO sheets, was synthesized by a one-pot in situ photoassisted method under visible-light irradiation, which was achieved without the addition of surfactant or a structure-directing reagent. For the first time, Co3 (PO4 )2 is demonstrated to act as a hydrogen evolving catalyst rather than being used as an oxygen evolving photoanode...
November 23, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27857001/symmetric-dynamic-behaviour-of-a-superconducting-proximity-array-with-respect-to-field-reversal
#13
M Lankhorst, N Poccia
As the complexity of strongly correlated systems and high temperature superconductors increases, so does also the essential complexity of defects found in these materials and the complexity of the supercurrent pathways. It can be therefore convenient to realize a solid-state system with regular supercurrent pathways and without the disguising effects of disorder in order to capture the essential characteristics of a collective dynamics. Using a square array of superconducting islands placed on a normal metal, we observe a state in which magnetic field-induced vortices are frozen in the dimples of the egg crate potential by their strong repulsion interaction...
January 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27848902/the-impact-of-mass-gathering-on-the-burden-of-multidrug-resistant-mycobacterium-tuberculosis-in-al-madinah-al-monawarah-region-saudi-arabia
#14
Mogahid Elhassan, Hassan A Hemeg, Miskelyemen A Elmekki, Khalid A Turkistani, Ahmed A Abdul-Aziz
BACKGROUND: The pattern of Mycobacterium tuberculosis susceptibility to first line drugs and multidrug resistance in Al-Madinah Al-Munawarah, a seasonally overcrowded are during Hajj and Omrah, is not well studied. OBJECTIVE: This study aimed to investigate anti-TB drug resistance and its distribution among new cases in Al-Madinah Al-Monawarah. METHODS: Study subjects included 622 patients with first time confirmed TB referred to the central tuberculosis laboratory in Al-Madinah between January 2012 and December 2014...
November 15, 2016: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/27846397/giving-the-community-a-voice-lessons-learned-from-a-comprehensive-survey-in-an-urban-neighborhood
#15
Tamar Mott Forrest, Dawn M Wallace-Pascoe, Michael D Webb, Howard Goldstein
Weinland Park, an urban neighborhood adjacent to The Ohio State University, has been targeted for revitalization following several decades of disinvestment. The goal of these efforts is to develop holistic solutions that break the cycle of poverty. Such an undertaking requires collecting baseline data to understand community needs, inform programming, and guide revitalization efforts. This paper describes the development and implementation of the Weinland Park Evaluation Project (WPEP) - a collaborative and comprehensive neighborhood survey and needs assessment...
February 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/27845934/localization-driven-metal-insulator-transition-in-epitaxial-hole-doped-nd1-x-sr-x-nio3-ultrathin-films
#16
Le Wang, Lei Chang, Xinmao Yin, Andrivo Rusydi, Lu You, Yang Zhou, Liang Fang, Junling Wang
Advances in thin film growth technologies make it possible to obtain ultra-thin perovskite oxide films and open the window for controlling novel electronic phases for use in functional nanoscale electronics, such as switches and sensors. Here, we study the thickness-dependent transport characteristics of high-quality ultrathin Nd0.9Sr0.1NiO3 (Sr-NNO) films, which were grown on LaAlO3 (0 0 1) single-crystal substrates by using pulsed laser deposition method. Thick Sr-NNO films (25 unit cells) exhibit metallic behavior with the electrical resistivity following the T ( n) (n  <  2) law corresponding to a non-Fermi liquid system, while a temperature driven metal-insulator transition (MIT) is observed with films of less than 15 unit cells...
January 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27845198/hyaluronan-35kda-treatment-protects-mice-from-citrobacter-rodentium-infection-and-induces-epithelial-tight-junction-protein-zo-1-in-vivo
#17
Yeojung Kim, Sean P Kessler, Dana R Obery, Craig R Homer, Christine McDonald, Carol A de la Motte
Maintaining a healthy intestinal barrier, the primary physical barrier between intestinal microbiota and the underlying lamina propria, is critical for optimal health. Epithelial integrity is essential for the prevention of the entrance of luminal contents, such as bacteria and their products, through the large intestinal barrier. In this study, we investigated the protective functions of biosynthetic, specific sized, hyaluronan around 35kDa (HA35) on intestinal epithelium in healthy mice, as well as mice infected Citrobacter rodentium, an established model that mimics infection with a serious human pathogen, enteropathogenic E...
November 11, 2016: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/27835008/from-a-quasimolecular-band-insulator-to-a-relativistic-mott-insulator-in-t_-2g-5-systems-with-a-honeycomb-lattice-structure
#18
Beom Hyun Kim, Tomonori Shirakawa, Seiji Yunoki
The t_{2g} orbitals of an edge-shared transition-metal oxide with a honeycomb lattice structure form dispersionless electronic bands when only hopping mediated by the edge-sharing oxygens is accessible. This is due to the formation of isolated quasimolecular orbitals (QMOs) in each hexagon, introduced recently by Mazin et al. [Phys. Rev. Lett. 109, 197201 (2012)], which stabilizes a band insulating phase for t_{2g}^{5} systems. However, with the help of the exact diagonalization method to treat the electron kinetics and correlations on an equal footing, we find that the QMOs are fragile against not only the spin-orbit coupling (SOC) but also the Coulomb repulsion...
October 28, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27831746/the-interrelationship-of-common-clinical-movement-screens-establishing-population-specific-norms-in-a-large-cohort-of-military-applicants
#19
Sarah J de la Motte, Timothy C Gribbin, Peter Lisman, Anthony I Beutler, Patricia Deuster
CONTEXT:  Musculoskeletal injuries (MSK-Is) are a leading cause of missed duty time and morbidity in the military. Modifiable risk factors for MSK-Is, such as inadequate core stability, poor movement patterns, and dynamic balance deficits, have not been identified in military applicants on entering service. OBJECTIVE:  To establish normative functional movement data using a series of screens in military applicants entering basic training and explore relationships among several movement tests...
November 10, 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/27830714/erratum-large-fermi-surface-of-heavy-electrons-at-the-border-of-mott-insulating-state-in-nis2
#20
S Friedemann, H Chang, M B Gamża, P Reiss, X Chen, P Alireza, W A Coniglio, D Graf, S Tozer, F M Grosche
No abstract text is available yet for this article.
November 10, 2016: Scientific Reports
keyword
keyword
68177
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"