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Sarah J de la Motte, Peter Lisman, Timothy C Gribbin, Kaitlin Murphy, Patricia A Deuster
We performed a systematic review and evaluation of the existing scientific literature on the association between flexibility, power, speed, balance, and agility, and musculoskeletal injury (MSK-I) risk in military and civilian populations. MEDLINE, EBSCO, EMBASE, and the Defense Technical Information Center were searched for original studies published from 1970 through 2015 that examined associations between these physical fitness measures (flexibility, power, speed, balance, and agility) and MSK-I. Methodological quality and strength of the evidence were determined following criteria adapted from previously published systematic reviews...
December 11, 2017: Journal of Strength and Conditioning Research
Maria Teresa Valenti, Monica Mottes, Alessandro Biotti, Massimiliano Perduca, Arianna Pisani, Michele Bovi, Michela Deiana, Samuele Cheri, Luca Dalle Carbonare
Osteoarthritis (OA), the most prevalent musculoskeletal pathology, is mainly characterized by the progressive degradation of articular cartilage due to an imbalance between anabolic and catabolic processes. Consequently, OA has been associated with defects in the chondrocitic differentiation of progenitor stem cells (PSCs). In addition, SOX9 is the transcription factor responsible for PSCs chondrogenic commitment. To evaluate the effects of the non-amino bisphosphonate clodronate in OA patients we investigated SOX9 gene expression in circulating progenitor cells (CPCs) and in an in vitro OA model...
December 13, 2017: International Journal of Molecular Sciences
Shohei Kumagai, Shinya Takaishi, Hiroaki Iguchi, Brian K Breedlove, Takuya Kaneko, Hiroshi Ito, Shin-Ichi Kuroda, Masahiro Yamashita
Hydrostatic (physical) pressure effects on the electrical resistivity of a bromido-bridged palladium compound, [Pd(en)2Br](Suc-C5)2·H2O, were studied. The charge-density-wave to Mott-Hubbard phase transition temperature (TPT) steadily increased with pressure. By a comparison of the effects of the chemical and physical pressures on TPT, it was estimated that the chemical pressure by unit alkyl chain length, i.e., the number of carbon atoms in the alkyl chains within the counterion, corresponded to ca. 1.3 kbar of the physical pressure...
December 11, 2017: Inorganic Chemistry
Sandra Mott, Niki Fogg, Naomi Foote, Maureen Hillier, Debra A Lewis, Betsy M McDowell, Kathleen Saunders, John T Taylor, Shirley Wiggins, Jean B Ivey, Casey O'Brien Benedetto, Patricia Hosang Beam, Kimberly B McKnight, Asma A Taha, Angelique Vann-Patterson
No abstract text is available yet for this article.
December 6, 2017: Journal of Pediatric Nursing
Honggyu Kim, Patrick B Marshall, Kaveh Ahadi, Thomas E Mates, Evgeny Mikheev, Susanne Stemmer
The lattice response of a prototype Mott insulator, SmTiO_{3}, to hole doping is investigated with atomic-scale spatial resolution. SmTiO_{3} films are doped with Sr on the Sm site with concentrations that span the insulating and metallic sides of the filling-controlled Mott metal-insulator transition (MIT). The GdFeO_{3}-type distortions are investigated using an atomic resolution scanning transmission electron microscopy technique that can resolve small lattice distortions with picometer precision. We show that these distortions are gradually and uniformly reduced as the Sr concentration is increased without any phase separation...
November 3, 2017: Physical Review Letters
K Tomiyasu, J Okamoto, H Y Huang, Z Y Chen, E P Sinaga, W B Wu, Y Y Chu, A Singh, R-P Wang, F M F de Groot, A Chainani, S Ishihara, C T Chen, D J Huang
We carried out temperature-dependent (20-550 K) measurements of resonant inelastic x-ray scattering on LaCoO_{3} to investigate the evolution of its electronic structure across the spin-state crossover. In combination with charge-transfer multiplet calculations, we accurately quantified the renomalized crystal-field excitation energies and spin-state populations. We show that the screening of the effective on-site Coulomb interaction of 3d electrons is orbital selective and coupled to the spin-state crossover in LaCoO_{3}...
November 10, 2017: Physical Review Letters
Zachary J Farrell, Christopher Tabor
Eutectic gallium-indium alloy (EGaIn, a room-temperature liquid metal) nanoparticles are of interest for their unique potential uses in self-healing and flexible electronic devices. One reason for their interest is due to a passivating oxide skin that develops spontaneously on exposure to ambient atmosphere which resists deformation and rupture of the resultant liquid particles. It is then of interest to develop methods for control of this oxide growth process. It is hypothesized here that functionalization of EGaIn nanoparticles with thiolated molecules could moderate oxide growth based on insights from the Cabrera-Mott oxidation model...
December 7, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
L Dalle Carbonare, V Micheletti, E Cosaro, M T Valenti, M Mottes, G Francia, M V Davì
CONTEXT: The high risk of vertebral fractures (VFs) in acromegaly patients despite normal bone mineral density (BMD) is well known. The reasons for this paradoxical finding of skeleton fragility are poorly understood due to the limited data on bone histomorphometry in acromegaly. OBJECTIVE: This study aimed to analyze histomorphometric parameters including bone microarchitecture in acromegaly patients with VFs and normal BMD compared to normal subjects, and also to evaluate the differences between active and controlled acromegaly patients...
December 6, 2017: Pituitary
Jenifer R Hajzus, Adam J Biacchi, Son T Le, Curt A Richter, Angela R Hight Walker, Lisa M Porter
Tin(ii) monosulfide (SnS) is a layered, anisotropic material that is of interest as a two-dimensional semiconductor for opto-electronic, thermoelectric, and piezoelectric applications. In this study, the effect of work function on contact behavior was investigated. Ni/Au, Pd/Au, Cr/Au, and Ti/Au contacts were fabricated onto individual, solution-synthesized, p-type SnS nanoribbons. The lower work function metals (Cr and Ti) formed Schottky contacts, whereas the higher work function metals (Ni and Pd) formed ohmic or semi-ohmic contacts...
December 7, 2017: Nanoscale
Malkeshkumar Patel, Mohit Kumar, Joondong Kim, Yu Kwon Kim
Photocathodes made from the earth-abundant, eco-friendly mineral tin monosulfide (SnS) can be promising candidates for p/n-type photoelectrochemical cells, since they meet the strict requirements of energy band edges for each individual photoelectrode. Herein we fabricated SnS-based cell that exhibited a prolonged photocurrent for 3 h at - 0.3 V vs. the reversible hydrogen electrode (RHE) in a 0.1 M HCl electrolyte. An enhancement of the cathodic photocurrent from 2 to 6 mA cm-2 is observed through a rapid thermal treatment...
December 6, 2017: Journal of Physical Chemistry Letters
Xinmao Yin, Chi Sin Tang, Muhammad Aziz Majidi, Peng Ren, Le Wang, Ping Yang, Caozheng Diao, Xiaojiang Yu, Mark B H Breese, Andrew Thye Shen Wee, Junling Wang, Andrivo Rusydi
Hole-doped perovskite manganites have attracted much attention because of their unique optical, electronic and magnetic properties induced by the interplay between spin, charge, orbital and lattice degrees of freedom. Here, a comprehensive investigation of the optical, electronic and magnetic properties of La0.7Sr0.3MnO3 thin-films on SrTiO3 (LSMO/STO) and other substrates is conducted using a combination of temperature-dependent transport, spectroscopic ellipsometry, X-ray absorption spectroscopy and X-ray magnetic circular dichroism...
December 6, 2017: ACS Applied Materials & Interfaces
G Adam Mott, Darrell Desveaux, David S Guttman
The first step in the plant immune response to pathogen challenge involves the perception of conserved epitopes, called microbe-associated molecular patterns (MAMPs), by cell surface pattern recognition receptors (PRRs). Given the key roles that MAMPs and PRRs play in plant innate immunity, great effort has been expended to identify these molecules. Current methods for assaying these immune responses are often limited in their resolution and throughput, and consequently, there is a need for medium- to high-throughput methodologies...
December 4, 2017: Molecular Plant-microbe Interactions: MPMI
Gregory R Keele, Jeremy W Prokop, Hong He, Katie Holl, John Littrell, Aaron Deal, Sanja Francic, Leilei Cui, Daniel M Gatti, Karl W Broman, Michael Tschannen, Shirng-Wern Tsaih, Maie Zagloul, Yunjung Kim, Brittany Baur, Joseph Fox, Melanie Robinson, Shawn Levy, Michael J Flister, Richard Mott, William Valdar, Leah C Solberg Woods
OBJECTIVE: Obesity is a major risk factor for multiple diseases and is in part heritable, yet the majority of causative genetic variants that drive excessive adiposity remain unknown. Here, outbred heterogeneous stock (HS) rats were used in controlled environmental conditions to fine-map novel genetic modifiers of adiposity. METHODS: Body weight and visceral fat pad weights were measured in male HS rats that were also genotyped genome-wide. Quantitative trait loci (QTL) were identified by genome-wide association of imputed single-nucleotide polymorphism (SNP) genotypes using a linear mixed effect model that accounts for unequal relatedness between the HS rats...
November 28, 2017: Obesity
Masaki Kobayashi, Kohei Yoshimatsu, Taichi Mitsuhashi, Miho Kitamura, Enju Sakai, Ryu Yukawa, Makoto Minohara, Atsushi Fujimori, Koji Horiba, Hiroshi Kumigashira
Controlling quantum critical phenomena in strongly correlated electron systems, which emerge in the neighborhood of a quantum phase transition, is a major challenge in modern condensed matter physics. Quantum critical phenomena are generated from the delicate balance between long-range order and its quantum fluctuation. So far, the nature of quantum phase transitions has been investigated by changing a limited number of external parameters such as pressure and magnetic field. We propose a new approach for investigating quantum criticality by changing the strength of quantum fluctuation that is controlled by the dimensional crossover in metallic quantum well (QW) structures of strongly correlated oxides...
November 30, 2017: Scientific Reports
Edwin W Huang, Christian B Mendl, Shenxiu Liu, Steve Johnston, Hong-Chen Jiang, Brian Moritz, Thomas P Devereaux
Upon doping, Mott insulators often exhibit symmetry breaking where charge carriers and their spins organize into patterns known as stripes. For high-transition temperature cuprate superconductors, stripes are widely suspected to exist in a fluctuating form. We used numerically exact determinant quantum Monte Carlo calculations to demonstrate dynamical stripe correlations in the three-band Hubbard model, which represents the local electronic structure of the copper-oxygen plane. Our results, which are robust to varying parameters, cluster size, and boundary conditions, support the interpretation of experimental observations such as the hourglass magnetic dispersion and the Yamada plot of incommensurability versus doping in terms of the physics of fluctuating stripes...
December 1, 2017: Science
Shaohui Wang, Kevin R Mott, Marianne Cilluffo, Casey L Kilpatrick, Shoko Murakami, Alexander V Ljubimov, Konstantin G Kousoulas, Sita Awasthi, Bernhard Luscher, Homayon Ghiasi
UL20, an essential HSV-1 protein, is involved in cytoplasmic envelopment of virions and virus egress. We reported recently that UL20 can bind to a host protein encoded by the zinc finger DHHC-type containing 3 (ZDHHC3) gene (also known as Golgi-specific DHHC zinc finger protein {GODZ}). Here, we show for the first time that HSV-1 replication is compromised in murine embryonic fibroblasts (MEFs) isolated from GODZ-/- mice. The absence of GODZ resulted in reduced palmitoylation of UL20 and altered localization, expression of UL20 and gK; the expression of gB and gC; and the localization and expression of tegument and capsid proteins within HSV-1-infected MEFs...
November 29, 2017: Journal of Virology
Roxanne E Kirsch, Jillian Coronado, Peter P Roeleveld, James Tweddell, Antonio M Mott, Stephen J Roth
We reflect upon highlights of a facilitated panel discussion from the 2016 Pediatric Cardiac Intensive Care Society Meeting. The session was designed to explore challenges, share practical clinical experiences, and review ethical underpinnings surrounding decisions to offer intensive, invasive therapies to patients who have a poor prognosis for survival or are likely to be burdened with multiple residual comorbidities if survival is achieved. The discussion panel was representative of a variety of disciplines including pediatric cardiology, cardiac intensive care, nursing, and cardiovascular surgery as well as different health-care delivery systems...
November 2017: World Journal for Pediatric & Congenital Heart Surgery
Chenue Abongwa, Sarah Mott, Blanca Schafer, Parren McNeely, Ghada Abusin, Thomas O'Dorisio, Gideon Zamba, M Sue O'Dorisio, Yusuf Menda
68Ga-DOTA-tyr3-Octreotide (68Ga-DOTATOC) PET/CT has been shown to have high accuracy in adults with neuroendocrine tumors, however has not been studied in pediatric patients. This study evaluated the safety and accuracy of 68Ga-DOTATOC PET/CT in children and young adults with solid tumors that express somatostatin receptor type 2. A series of three prospective, IRB approved, clinical trials evaluating safety and efficacy of 68Ga-DOTATOC PET/CT were conducted for subjects aged 6 months to 90 years. This study reports the results for the 26 children and young adults, aged 16 months to 29 years who participated in these trials...
2017: American Journal of Nuclear Medicine and Molecular Imaging
M Shimozawa, K Hashimoto, A Ueda, Y Suzuki, K Sugii, S Yamada, Y Imai, R Kobayashi, K Itoh, S Iguchi, M Naka, S Ishihara, H Mori, T Sasaki, M Yamashita
Strongly enhanced quantum fluctuations often lead to a rich variety of quantum-disordered states. Developing approaches to enhance quantum fluctuations may open paths to realize even more fascinating quantum states. Here, we demonstrate that a coupling of localized spins with the zero-point motion of hydrogen atoms, that is, proton fluctuations in a hydrogen-bonded organic Mott insulator provides a different class of quantum spin liquids (QSLs). We find that divergent dielectric behavior associated with the approach to hydrogen-bond order is suppressed by the quantum proton fluctuations, resulting in a quantum paraelectric (QPE) state...
November 28, 2017: Nature Communications
Imen Ben Amara, Aida Hichri, Sihem Jaziri
Electronic and optical performances of the β-InSe monolayer (ML) are considerably boosted by tuning the corresponding band energies through lattice in-plane compressive strain engineering. First principles calculations show an indirect-direct gap transition with a large bandgap size. The crossover is due to different responses of the near-gap state energies with respect to strain. This is explained by the variation of In-Se bond length, the bond nature of near-band-edge electronic orbital and of the momentum angular contribution versus in-plane compressive strain...
November 24, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
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