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https://www.readbyqxmd.com/read/29661263/a-new-microsporidium-percutemincola-moriokae-gen-nov-sp-nov-from-oscheius-tipulae-a-novel-model-of-microsporidia-nematode-associations
#1
Kenji Nishikori, Davin H E Setiamarga, Takahiro Tanji, Eisuke Kuroda, Hirohisa Shiraishi, Ayako Ohashi-Kobayashi
Here, we describe a new microsporidium Percutemincola moriokae gen. nov., sp. nov., which was discovered in the intestinal and hypodermal cells of a wild strain of the nematode Oscheius tipulae that inhabits in the soil of Morioka, Iwate Prefecture, Japan. The spores of Pe. moriokae had an average size of 1.0 × 3.8 µm and 1.3 × 3.2 µm in the intestine and hypodermis, respectively, and electron microscopy revealed that they exhibited distinguishing features with morphological diversity in the hypodermis...
April 17, 2018: Parasitology
https://www.readbyqxmd.com/read/29620631/pediatric-hyperimmunoglobulin-e-syndrome-a-case-series-of-4-children-in-china
#2
Huifeng Fan, Li Huang, Diyuan Yang, Yunting Lin, Gen Lu, Yaping Xie, Jialu Yu, Dongwei Zhang
Hyperimmunoglobulin E syndromes (HIES) are rare primary immunodeficiency diseases characterized by markedly elevated serum immunoglobulin (Ig) E, recurrent pneumonia, and chronic eczema. To date, information about pediatric HIES is limited. We aimed to evaluate the spectrum of clinical and immunological features in pediatric patients with HIES in China.We retrospectively reviewed the cases of 4 pediatric patients with HIES followed at the Guangzhou Women and Children's Medical Center from May 2013 to September 2017...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29599387/clinical-and-sexual-risk-correlates-of-mycoplasma-genitalium-in-urban-pregnant-and-non-pregnant-young-women-cross-sectional-outcomes-using-the-baseline-data-from-the-women-s-biohealth-study
#3
Maria Trent, Jenell S Coleman, Justin Hardick, Jamie Perin, Lisa Tabacco, Steven Huettner, Jocelyn Ronda, Rebecca Felter-Wernsdorfer, Charlotte A Gaydos
OBJECTIVE: Research exploring the clinical and sexual risk correlates is essential to define universal standards for screening and management for Mycoplasma genitalium (MG). The objective of this study is to determine the baseline prevalence of MG and associated clinical risks using cross-sectional data. METHODS: Adolescent and young adult women 13-29 years were recruited during clinical visits during which biological specimens were collected for Neisseriagonorrhoeae (NG) and Chlamydia trachomatis (CT) testing to provide vaginal specimens for MG and Trichomonasvaginalis (TV) testing...
March 29, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29599157/draft-genome-sequence-of-an-ndm-1-and-kpc-2-coproducing-hypervirulent-carbapenem-resistant-klebsiella-pneumoniae-strain-isolated-from-burn-wound-infections
#4
Dan-Dan Wei, La-Gen Wan, Yang Liu
We report here the draft genome sequence of an NDM-1- and KPC-2-coproducing hypervirulent carbapenem-resistant Klebsiella pneumoniae strain, isolated from a 58-year-old male in the People's Republic of China with a burn injury.
March 29, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29570761/treatment-of-lateral-tibial-condylar-fractures-using-bioactive-bioresorbable-forged-composites-of-raw-particulate-unsintered-hydroxyapatite-poly-l-lactide-screws
#5
Gen Kuroyanagi, Hiroyuki Yoshihara, Naohiro Yamamoto, Hiroyuki Suzuki, Kunio Yamada, Yukio Yoshida, Takanobu Otsuka, Naoya Takada
Forged composites of raw particulate unsintered hydroxyapatite/poly-L-lactide (F-u-HA/PLLA) devices possess high mechanical strength, bioactivity, and radio-opacity. The aim of this study was to assess the efficacy of F-u-HA/PLLA screws in the treatment of lateral tibial condylar fractures. From January 2005 to December 2010, a total of 7 patients with displaced closed lateral tibial condylar fractures (Schatzker type II) were treated using F-u-HA/PLLA screws. Open reduction and internal fixation was performed using 2 or 3 F-u-HA/PLLA screws...
March 23, 2018: Orthopedics
https://www.readbyqxmd.com/read/29568205/epidemiological-features-of-chronic-hepatitis-c-infection-caused-by-remunerated-blood-donors-a-nearly-27-year-period-survey
#6
You-Wen Tan, Yan Tao, Long-Gen Liu, Yun Ye, Xin-Bei Zhou, Li Chen, Cong He
AIM: To understand the prevalence of hepatitis C virus (HCV) infection in blood donors over a nearly 27-year interval and to explore the factors that affect the outcome of HCV infection. METHODS: A retrospective and cross-sectional study was conducted. The participants, mostly plasma donors, were selected from three administrative villages in the Jiangsu province in Eastern China. A questionnaire was administered among the villagers who had a history of blood donation from the late 1980s to the early 1990s...
March 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29565724/molecular-epidemiology-and-virulence-features-of-staphylococcus-aureus-bloodstream-isolates-in-a-regional-burn-center-in-china-2012-2016
#7
Yang Liu, Fang-Ling Du, Pan-Pan Liu, Yan-Fang Mei, La-Gen Wan, Dan-Dan Wei, Heng-Yi Xu, Wei Zhang
Staphylococcus aureus is known to be a predominant pathogen causing bloodstream infection (BSI) from burn units. Our study aimed to perform the clinical epidemiological analysis and virulence features of S. aureus strains isolated from the burn patients with BSI from a burn center in southeastern China during 2012-2016. A collection of 112 S. aureus isolates causing BSI from burn center of a tertiary care hospital in China was carried out. Antimicrobial susceptibility testing was conducted in accordance with the Clinical and Laboratory Standards Institute (CLSI) guidelines...
March 22, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29536713/-investigation-of-major-parasitic-diseases-and-related-knowledge-attitude-and-practice-among-rural-residents-in-liyang-city
#8
Guo Yan-Li, Zou Yong-Gen, Xie Yi-Qing, Chen Hong, He Ming-Zhen, Lü Lai-Fu, Huang Li-Zhong, Jin Xiao-Lin
OBJECTIVE: To investigate the prevalence of major parasitic diseases and related knowledge, attitude and practice among rural residents in Liyang City, so as to provide the evidence for formulating appropriate preventive strategies and measures. METHODS: Three villages were selected from three towns as survey sites, and the residents who were above three years old and had been in the village for over six months were investigated. The Kato-Katz technique was applied to detect intestinal parasite eggs in residents' feces, and the cellophane anal swab was used to detect Enterobius vermicularis eggs among children aged 3-6 years...
September 27, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29530610/effects-of-chinese-herbal-medicine-on-hyperlipidemia-and-the-risk-of-cardiovascular-disease-in-hiv-infected-patients-in-taiwan
#9
Fuu-Jen Tsai, Te-Mao Li, Chi-Fung Cheng, Yang-Chang Wu, Chih-Ho Lai, Tsung-Jung Ho, Xiang Liu, Hsinyi Tsang, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Ju-Pi Li, Jung-Chun Lin, Chih-Chien Lin, Wen-Miin Liang, Ying-Ju Lin
ETHNOPHARMACOLOGICAL RELEVANCE: Due to the development of antiretroviral therapy (ART), HIV/AIDS is now regarded as a treatable chronic disease. Chinese herbal medicine (CHM) is a type of complementary and alternative medicine (CAM) that has been widely applied in the healthcare system in Taiwan. AIM OF THE STUDY: The aim of this study was to investigate the frequency of use and patterns of prescription for the CHM-based treatment of HIV-infected patients and to assess the long-term effects of CHM on hyperlipidemia and cardiovascular disease events in these patients...
March 9, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29528385/effect-of-faecal-microbiota-transplantation-for-treatment-of-clostridium-difficile-infection-in-patients-with-inflammatory-bowel-disease-a-systematic-review-and-meta-analysis-of-cohort-studies
#10
Tuo Chen, Qun Zhou, Dan Zhang, Feng Jiang, Jing Wu, Jin-Yong Zhou, Xiao Zheng, Yu-Gen Chen
Background: Evidence concerning the effect of faecal microbiota transplantation (FMT) in Clostridium difficile infection (CDI) patients with inflammatory bowel disease (IBD) has not been firmly established. Therefore, we performed a systematic review and meta-analysis to evaluate FMT treatment outcomes in patients with IBD treated for CDI. Methods: An electronic search of four databases was conducted until November 1st, 2017. Cohort studies of FMT efficacy and safety in CDI patients with IBD were included...
March 8, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29518389/smurf1-restricts-the-antiviral-function-mediated-by-usp25-through-promoting-its-ubiquitination-and-degradation
#11
Guanghui Qian, Xiaohan Hu, Gen Li, Yueyue Ding, Liyan Zhu, Hui Zheng, Mei Li, Zhiheng Li, Jian Pan, Yiping Li, Gang Li, Chun Yang, Ying Liu, Yi Xie, Haitao Lv
Protein ubiquitination and deubiquitination enzymes are widely involved in innate immune responses. The ubiquitin specific protease 25 (USP25), a deubiquitinating enzyme, has been demonstrated to play an important role in virus infection and immunity. However, how USP25 is degraded and regulated by E3 ubiquitin ligases remains poorly understood. Here, we identified Smad ubiquitin regulatory factor 1(Smurf1) as a first novel E3 ubiquitin ligase of USP25. Smurf1 overexpression decreases USP25 protein turnover, and the E3 ligase enzymatic activity of Smurf1 is required for USP25 degradation...
March 5, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29510283/one-or-two-drains-for-the-treatment-of-surgical-site-infections-after-lumbar-spine-surgery
#12
Ying-Chun Chen, Lin Zhang, Er-Nan Li, Li-Xiang Ding, Gen-Ai Zhang, Yu Hou, Wei Yuan
BACKGROUND: The optimal drainage after debridement for treating postoperative SSI is still controversial. We comprehensively compared single-tube drainage method with double-tube drainage method. MATERIALS AND METHODS: We retrospectively analyzed 1125 patients with lumbar degenerative disease who received lumbar surgery. Among them, 26 patients were diagnosed as postoperative SSI and divided into two groups, including single-tube drainage group (1 drain) and double-tube drainage group (2 drains)...
March 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29508598/-oncomelania-hupensis-status-monitoring-in-changzhou-city-jiangsu-province-from-2013-to-2016
#13
H E Ming-Zhen, X Yi-Qing, C Hong, Z Yong-Gen, Z Shi-Ying, G Yan-Li
Objective To analyze the Oncomelania hupensis snail distribution and the changes of snail situation in Changzhou City from 2013 to 2016, so as to provide the evidence for formulating the schistosomiasis prevention and control interventions. Methods The data of snail monitoring in Changzhou City from 2013 to 2016 were collected and statistically analyzed. Results The total area with snails was 40.17 hm2 and the newly discovered area was 30.63 hm2 in Changzhou City from 2013 to 2016. In the four years, 3 454 snails were dissected, and no schistosome infected snails were found...
April 27, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29508591/-infection-status-of-toxoplasma-gondii-and-its-related-knowledge-and-behavior-among-special-population-in-changzhou-city
#14
G Yan-Li, X Yi-Qing, Z Yong-Gen, X U Da-Cheng, X U Wen-Wei, D Yang, S Ming-Xue
Objective To investigate the prevalence of Toxoplasma gondii infection and related knowledge and behavior among special population in Changzhou City, so as to provide the evidence for formulating effective measures of toxoplasmosis prevention. Methods The pregnant women and patients with neoplasia in Changzhou hospitals, and livestock and poultry breeding or processing workers were selected as the subjects of the study. Venous blood samples were collected from each participant for detecting IgG and IgM antibodies against T...
March 20, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29477669/the-chytrid-like-parasites-of-algae-amoeboradix-gromovi-gen-et-sp-nov-and-sanchytrium-tribonematis-belong-to-a-new-fungal-lineage
#15
Sergey A Karpov, Purificación López-García, Maria A Mamkaeva, Vladimir I Klimov, Andrey E Vishnyakov, Victoria S Tcvetkova, David Moreira
Fungi encompass, in addition to classically well-studied lineages, an ever-expanding diversity of poorly known lineages including zoosporic chytrid-like parasites. Here, we formally describe Amoeboradix gromovi gen. et sp. nov. comprising a set of closely related strains of chytrid-like parasites of the yellow-green alga Tribonema gayanum unusually endowed with amoeboid zoospores. Morphological and ultrastructural features of A. gromovi observed by light and transmission electron microscopy recall previous descriptions of Rhizophydium anatropum...
November 21, 2017: Protist
https://www.readbyqxmd.com/read/29469448/-trends-of-soil-transmitted-nematode-infections-in-jiangxi-province
#16
Zeng Xiao-Jun, Jiang Wei-Sheng, Xie Shu-Ying, Ge Jun, Li Zhao-Jun, Hang Chun-Qin, Liu Yue-Min, Yi Fang-Yu, Chen Hong-Gen
OBJECTIVE: To analyze the status and trends of soil-transmitted nematode infections in Jiangxi Province from 1989 to 2014, so as to provide the evidence for generating the strategy of soil-transmitted nematode prevention and control. METHODS: The data of three epidemiological surveys on human parasitic diseases (in 1989, 2002 and 2014) were classified and analyzed. The stool examination by Kato-Katz's thick smear method was adopted for the investigation of soil-transmitted nematode infections...
December 5, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29449171/changes-in-antimicrobial-susceptibility-of-commonly-clinically-significant-isolates-before-and-after-the-interventions-on-surgical-prophylactic-antibiotics-spas-in-shanghai
#17
Su Wang, Li-Zhong Han, Yu-Xing Ni, Yi-Bo Zhang, Qun Wang, Da-Ke Shi, Wen-Hui Li, Yi-Chen Wang, Chen-Rong Mi
Surveillances and interventions on antibiotics use have been suggested to improve serious drug-resistance worldwide. Since 2007, our hospital have proposed many measures for regulating surgical prophylactic antibiotics (carbapenems, third gen. cephalosporins, vancomycin, etc.) prescribing practices, like formulary restriction or replacement for surgical prophylactic antibiotics and timely feedback. To assess the impacts on drug-resistance after interventions, we enrolled infected patients in 2006 (pre-intervention period) and 2014 (post-intervention period) in a tertiary hospital in Shanghai...
February 12, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29444284/gentamicin-intercalated-smectite-as-a-new-therapeutic-option-for-helicobacter-pylori-eradication
#18
Su Jin Jeong, Jie-Hyun Kim, Da Hyun Jung, Kyoung Hwa Lee, Soon Young Park, Yungoo Song, Il-Mo Kang, Young Goo Song
Objectives: Novel antibacterial strategies against Helicobacter pylori are needed because H. pylori strains are acquiring resistance to antibiotics. We evaluated the efficacy of gentamicin-intercalated smectite hybrid (S-GEN)-based treatment regimens in a murine model of H. pylori infection. Methods: Two groups of 10 rats were administered either smectite or S-GEN to measure coverage of the gastric mucosa. To evaluate anti-H. pylori efficacy, mice were divided into eight groups of 10 mice each given different treatments, and H...
February 12, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29433688/synergism-of-prenylflavonoids-from-morus-alba-root-bark-against-clinical-mrsa-isolates
#19
Guo-Ying Zuo, Cui-Xian Yang, Jun Han, Yu-Qing Li, Gen-Chun Wang
BACKGROUND: Clinical methicillin-resistant Staphylococcus aureus (MRSA) is a thorny problem in current anti-infective therapeutics and a challenge of new drug development. Plant prenylflavonoids possess anti-MRSA activity, but few of the prenylflavonoids have been reported the synergistic anti-MRSA effect when they are used in combination with conventional antibacterial agents. PURPOSE: This study deals with anti-MRSA activity of four prenylflavonoids from the root bark of Morus alba and their synergism with 11 conventional antibacterial agents...
January 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29424149/-inversive-liss-plate-in-treating-intertrochanteric-and-subtrochanteric-fractures-combined-with-femoral-shaft-fractures
#20
Lei Han, Yun-Gen Hu, Wei-Li Fang, Bo Jin, Shi-Chao Xu
OBJECTIVE: To study clinical effects of inversive LISS(less invasive stabilization system, LISS) plate for the treatment of intertrochanteric and subtrochanteric fractures combined with femoral shaft fractures. METHODS: From January 2012 to January 2015, 24 patients with intertrochanteric and subtrochanteric fractures combined with femoral shaft fractures were treated with inversive LISS plate, included 16 males and 8 females with an average age of 62.5 years old ranged from 35 to 81 years old...
July 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
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