Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Jae W Song, Megan Y Frame, Rob T Sellers, Connie Klahn, Kevin Fitzgerald, Bridget Pomponio, Mitchell D Schnall, Scott E Kasner, Laurie A Loevner
BACKGROUND AND PURPOSE: The slow adoption of new advanced imaging techniques into clinical practice has been a long-standing challenge. Principles of implementation science and the reach, effectiveness, adoption, implementation, maintenance (RE-AIM) framework were used to build a clinical vessel wall imaging program at an academic medical center. MATERIALS AND METHODS: Six phases for implementing a clinical vessel wall MR imaging program were contextualized to the RE-AIM framework...
March 21, 2024: AJNR. American Journal of Neuroradiology
#2
JOURNAL ARTICLE
Michael Chen, Krishna C Joshi, Bradley Kolb, Clark W Sitton, Deep Kiritbhai Pujara, Michael G Abraham, Santiago Ortega-Gutierrez, Scott E Kasner, Shazam M Hussain, Leonid Churilov, Spiros Blackburn, Sophia Sundararajan, Yin C Hu, Nabeel Herial, Juan F Arenillas, Jenny P Tsai, Ronald F Budzik, William Hicks, Osman Kozak, Bernard Yan, Dennis Cordato, Nathan W Manning, Mark Parsons, Ricardo A Hanel, Amin Aghaebrahim, Teddy Wu, Pere Cardona Portela, Chirag D Gandhi, Fawaz Al-Mufti, Natalia Perez de la Ossa, Joanna Schaafsma, Jordi Blasco, Navdeep Sangha, Steven Warach, Timothy J Kleinig, Hannah Johns, Faris Shaker, Mohammad A Abdulrazzak, Abhishek Ray, Jeffery Sunshine, Amanda Opaskar, Kelsey R Duncan, Wei Xiong, Faisal K Al-Shaibi, Edgar A Samaniego, Thanh N Nguyen, Johanna T Fifi, Stavropoula I Tjoumakaris, Pascal Jabbour, Vitor Mendes Pereira, Maarten G Lansberg, Cathy Sila, Nicholas C Bambakidis, Stephen Davis, Lawrence Wechsler, Gregory W Albers, James C Grotta, Marc Ribo, Ameer E Hassan, Bruce Campbell, Michael D Hill, Amrou Sarraj
BACKGROUND: The incidence of intracerebral hemorrhage (ICH) and its effect on the outcomes after endovascular thrombectomy (EVT) for patients with large core infarcts have not been well-characterized. METHODS: SELECT2 trial follow-up imaging was evaluated using the Heidelberg Bleeding Classification (HBC) to define hemorrhage grade. The association of ICH with clinical outcomes and treatment effect was examined. RESULTS: Of 351 included patients, 194 (55%) and 189 (54%) demonstrated intracranial and intracerebral hemorrhage, respectively, with a higher incidence in EVT (134 (75%) and 130 (73%)) versus medical management (MM) (60 (35%) and 59 (34%), both P<0...
March 12, 2024: Journal of Neurointerventional Surgery
#3
JOURNAL ARTICLE
Jia Nong, Patrick M Glassman, Vladimir V Shuvaev, Sahily Reyes-Esteves, Helene C Descamps, Raisa Y Kiseleva, Tyler E Papp, Mohamad-Gabriel Alameh, Ying K Tam, Barbara L Mui, Serena Omo-Lamai, Marco E Zamora, Tea Shuvaeva, Evguenia Arguiri, Xijing Gong, Taylor V Brysgel, Ai Wen Tan, Ashley G Woolfork, Aalim Weljie, Christoph A Thaiss, Jacob W Myerson, Drew Weissman, Scott E Kasner, Hamideh Parhiz, Vladimir R Muzykantov, Jacob S Brenner, Oscar A Marcos-Contreras
Effective delivery of mRNA or small molecule drugs to the brain is a significant challenge in developing treatment for acute ischemic stroke. To address the problem, we have developed targeted nanomedicine to increase drug concentrations in endothelial cells of the blood-brain barrier (BBB) of the injured brain. Inflammation during ischemic stroke causes continuous neuronal death and increase of the infarct volume. To enable targeted delivery to the inflamed BBB, we conjugated lipid nanocarriers with antibodies that bind cell adhesion molecules expressed at the BBB...
March 6, 2024: Molecular Therapy
#4
JOURNAL ARTICLE
Michela Rosso, Helena Stengl, Ramanan Ganeshan, Simon Hellwig, Markus G Klammer, Regina von Rennenberg, Sophie Böhme, Christian H Nolte, Heinrich J Audebert, Matthias Endres, Scott E Kasner, Jan F Scheitz
BACKGROUND: Sex differences in presentation, treatment, and prognosis of cardiovascular disorders are well recognized. Although an association between acute myocardial injury and mortality after ischemic stroke has been demonstrated, it is unclear whether prevalence and outcome of poststroke acute myocardial injury differ between women and men. METHODS AND RESULTS: We prospectively screened consecutive patients with acute ischemic stroke and serial high-sensitivity cardiac troponin T measurements admitted to our center...
March 5, 2024: Journal of the American Heart Association
#5
JOURNAL ARTICLE
Jens Witsch, Quy Cao, Jae W Song, Yunshi Luo, Kelly L Sloane, Aaron Rothstein, Christopher G Favilla, Brett L Cucchiara, Scott E Kasner, Steve R Messé, Huimahn A Choi, Louise D McCullough, Stephan A Mayer, Aaron M Gusdon
BACKGROUND: Although larger hematoma volume is associated with worse outcome after intracerebral hemorrhage (ICH), the association between perihematomal edema (PHE) volume and outcome remains uncertain, as does the impact of sex on PHE and outcome. Here we aimed to determine whether larger PHE volume is associated with worse outcome and whether PHE volume trajectories differ by sex. METHODS: We conducted a post hoc analysis of the Factor VIIa for Acute Hemorrhagic Stroke Treatment (FAST) trial, which randomized patients with ICH to receive recombinant activated factor VIIa or placebo...
February 20, 2024: Neurocritical Care
#6
JOURNAL ARTICLE
Scott E Kasner, Lars Sondergaard, Mitesh Nakum, Melissa Gomez Montero, Mahmoud Hashim, Erik J Landaas
AIMS: Two randomized clinical trials, REDUCE and RESPECT, demonstrated that patent foramen ovale (PFO) closure in combination with antithrombotic therapy was more effective for the prevention of recurrent ischemic stroke compared with antithrombotic therapy alone. The aim of this study was to determine the relative efficacy and safety of the PFO closure devices used in REDUCE (HELEX and CARDIOFORM Septal Occluders) compared with the device used in RESPECT (Amplatzer PFO Occluder). METHODS: An unanchored matching-adjusted indirect comparison (MAIC) of the PFO closure arms of the REDUCE and RESPECT trials was performed using patient-level data from REDUCE weighted to match baseline characteristics from RESPECT...
February 19, 2024: Journal of Medical Economics
#7
JOURNAL ARTICLE
Amrou Sarraj, Michael D Hill, M Shazam Hussain, Michael G Abraham, Santiago Ortega-Gutierrez, Michael Chen, Scott E Kasner, Leonid Churilov, Deep K Pujara, Hannah Johns, Spiros Blackburn, Sophia Sundararajan, Yin C Hu, Nabeel A Herial, Ronald F Budzik, William J Hicks, Juan F Arenillas, Jenny P Tsai, Osman Kozak, Dennis J Cordato, Ricardo A Hanel, Teddy Y Wu, Pere Cardona Portela, Chirag D Gandhi, Fawaz Al-Mufti, Laith Maali, Daniel Gibson, Natalia Pérez de la Ossa, Joanna D Schaafsma, Jordi Blasco, Navdeep Sangha, Steven Warach, Timothy J Kleinig, Faris Shaker, Clark W Sitton, Thanh Nguyen, Johanna T Fifi, Pascal Jabbour, Anthony Furlan, Maarten G Lansberg, Georgios Tsivgoulis, Cathy Sila, Nicholas Bambakidis, Stephen Davis, Lawrence Wechsler, Greg W Albers, James C Grotta, Marc Ribo, Bruce C Campbell, Ameer E Hassan, Nirav Vora, Nathan W Manning, Andrew Cheung, Amin N Aghaebrahim, Andres J Paipa Merchán, Daniel Sahlein, Manuel Requena Ruiz, Lucas Elijovich, Adam Arthur, Faisal Al-Shaibi, Edgar A Samaniego, Kelsey R Duncan, Amanda Opaskar, Abhishek Ray, Wei Xiong, Jeffery Sunshine, Michael DeGeorgia, Stavropoula Tjoumakaris, Vitor Mendes Pereira
IMPORTANCE: Patients with large ischemic core stroke have poor clinical outcomes and are frequently not considered for interfacility transfer for endovascular thrombectomy (EVT). OBJECTIVE: To assess EVT treatment effects in transferred vs directly presenting patients and to evaluate the association between transfer times and neuroimaging changes with EVT clinical outcomes. DESIGN, SETTING, AND PARTICIPANTS: This prespecified secondary analysis of the SELECT2 trial, which evaluated EVT vs medical management (MM) in patients with large ischemic stroke, evaluated adults aged 18 to 85 years with acute ischemic stroke due to occlusion of the internal carotid or middle cerebral artery (M1 segment) as well as an Alberta Stroke Program Early CT Score (ASPECTS) of 3 to 5, core of 50 mL or greater on imaging, or both...
February 8, 2024: JAMA Neurology
#8
JOURNAL ARTICLE
Michela Rosso, Srinath Ramaswamy, Yohannes Mulatu, Jessica N Little, Nino Kvantaliani, Ankita Brahmaroutu, Izabella Marczak, Jennifer Lewey, Rajat Deo, Steven R Messé, Brett L Cucchiara, Steven R Levine, Scott E Kasner
BACKGROUND: Elevated cardiac troponin (cTn) is detected in 10% to 30% of patients with acute ischemic stroke (AIS) and correlates with poor functional outcomes. Serial cTn measurements differentiate a dynamic cTn pattern (rise/fall >20%), specific for acute myocardial injury, from elevated but stable cTn levels (nondynamic), typically attributed to chronic cardiac/noncardiac conditions. We investigated if the direction of the cTn change (rising versus falling) affects mortality and outcome...
February 20, 2024: Journal of the American Heart Association
#9
RANDOMIZED CONTROLLED TRIAL
Amrou Sarraj, Michael G Abraham, Ameer E Hassan, Spiros Blackburn, Scott E Kasner, Santiago Ortega-Gutierrez, Muhammad Shazam Hussain, Michael Chen, Hannah Johns, Leonid Churilov, Deep K Pujara, Faris Shaker, Laith Maali, Pere Cardona Portela, Nabeel A Herial, Daniel Gibson, Osman Kozak, Juan F Arenillas, Bernard Yan, Natalia Pérez de la Ossa, Sophia Sundararajan, Yin C Hu, Dennis J Cordato, Nathan W Manning, Ricardo A Hanel, Amin N Aghaebrahim, Ronald F Budzik, William J Hicks, Jordi Blasco, Teddy Y Wu, Jenny P Tsai, Joanna D Schaafsma, Chirag D Gandhi, Fawaz Al-Mufti, Navdeep Sangha, Steven Warach, Timothy J Kleinig, Vignan Yogendrakumar, Felix Ng, Edgar A Samaniego, Mohammad A Abdulrazzak, Mark W Parsons, Mohammad H Rahbar, Thanh N Nguyen, Johanna T Fifi, Vitor Mendes Pereira, Maarten G Lansberg, Greg W Albers, Anthony J Furlan, Pascal Jabbour, Clark W Sitton, Cathy Sila, Nicholas Bambakidis, Stephen M Davis, Lawrence Wechsler, Michael D Hill, James C Grotta, Marc Ribo, Bruce C V Campbell
BACKGROUND: Multiple randomised trials have shown efficacy and safety of endovascular thrombectomy in patients with large ischaemic stroke. The aim of this study was to evaluate long-term (ie, at 1 year) evidence of benefit of thrombectomy for these patients. METHODS: SELECT2 was a phase 3, open-label, international, randomised controlled trial with blinded endpoint assessment, conducted at 31 hospitals in the USA, Canada, Spain, Switzerland, Australia, and New Zealand...
February 24, 2024: Lancet
#10
JOURNAL ARTICLE
Hooman Kamel, W T Longstreth, David L Tirschwell, Richard A Kronmal, Randolph S Marshall, Joseph P Broderick, Rebeca Aragón García, Pamela Plummer, Noor Sabagha, Qi Pauls, Christy Cassarly, Catherine R Dillon, Marco R Di Tullio, Eldad A Hod, Elsayed Z Soliman, David J Gladstone, Jeff S Healey, Mukul Sharma, Seemant Chaturvedi, L Scott Janis, Balaji Krishnaiah, Fadi Nahab, Scott E Kasner, Robert J Stanton, Dawn O Kleindorfer, Matthew Starr, Toni R Winder, Wayne M Clark, Benjamin R Miller, Mitchell S V Elkind
IMPORTANCE: Atrial cardiopathy is associated with stroke in the absence of clinically apparent atrial fibrillation. It is unknown whether anticoagulation, which has proven benefit in atrial fibrillation, prevents stroke in patients with atrial cardiopathy and no atrial fibrillation. OBJECTIVE: To compare anticoagulation vs antiplatelet therapy for secondary stroke prevention in patients with cryptogenic stroke and evidence of atrial cardiopathy. DESIGN, SETTING, AND PARTICIPANTS: Multicenter, double-blind, phase 3 randomized clinical trial of 1015 participants with cryptogenic stroke and evidence of atrial cardiopathy, defined as P-wave terminal force greater than 5000 μV × ms in electrocardiogram lead V1, serum N-terminal pro-B-type natriuretic peptide level greater than 250 pg/mL, or left atrial diameter index of 3 cm/m2 or greater on echocardiogram...
February 20, 2024: JAMA
#11
JOURNAL ARTICLE
Amrou Sarraj, Ameer E Hassan, Michael G Abraham, Santiago Ortega-Gutierrez, Scott E Kasner, Muhammad Shazam Hussain, Michael Chen, Leonid Churilov, Hannah Johns, Clark W Sitton, Vignan Yogendrakumar, Felix C Ng, Deep K Pujara, Spiros Blackburn, Sophia Sundararajan, Yin C Hu, Nabeel A Herial, Juan F Arenillas, Jenny P Tsai, Ronald F Budzik, William J Hicks, Osman Kozak, Bernard Yan, Dennis J Cordato, Nathan W Manning, Mark W Parsons, Andrew Cheung, Ricardo A Hanel, Amin N Aghaebrahim, Teddy Y Wu, Pere Cardona Portela, Chirag D Gandhi, Fawaz Al-Mufti, Natalia Pérez de la Ossa, Joanna D Schaafsma, Jordi Blasco, Navdeep Sangha, Steven Warach, Timothy J Kleinig, Faris Shaker, Faisal Al Shaibi, Gabor Toth, Mohammad A Abdulrazzak, Gagan Sharma, Abhishek Ray, Jeffrey Sunshine, Amanda Opaskar, Kelsey R Duncan, Wei Xiong, Edgar A Samaniego, Laith Maali, Colleen G Lechtenberg, Arturo Renú, Nirav Vora, Thanh Nguyen, Johanna T Fifi, Stavropoula I Tjoumakaris, Pascal Jabbour, Georgios Tsivgoulis, Vitor Mendes Pereira, Maarten G Lansberg, Michael DeGeorgia, Cathy A Sila, Nicholas Bambakidis, Michael D Hill, Stephen M Davis, Lawrence Wechsler, James C Grotta, Marc Ribo, Greg W Albers, Bruce C Campbell
IMPORTANCE: Whether endovascular thrombectomy (EVT) efficacy for patients with acute ischemic stroke and large cores varies depending on the extent of ischemic injury is uncertain. OBJECTIVE: To describe the relationship between imaging estimates of irreversibly injured brain (core) and at-risk regions (mismatch) and clinical outcomes and EVT treatment effect. DESIGN, SETTING, AND PARTICIPANTS: An exploratory analysis of the SELECT2 trial, which randomized 352 adults (18-85 years) with acute ischemic stroke due to occlusion of the internal carotid or middle cerebral artery (M1 segment) and large ischemic core to EVT vs medical management (MM), across 31 global centers between October 2019 and September 2022...
March 5, 2024: JAMA
#12
JOURNAL ARTICLE
Naga Venkata K Pothineni, Uyanga Batnyam, Hannah Schwennesen, Ann Tierney, Steven R Messé, Brett Cucchiara, Todd B Mendelson, Jeffrey J Luebbert, Wei Yang, Ramanan Kumareswaran, Matthew C Hyman, David Lin, Sanjay Dixit, Andrew E Epstein, Jeffrey S Arkles, Saman Nazarian, Robert D Schaller, Gregory E Supple, David Callans, Amaryah Yaeger, David S Frankel, Pasquale Santangeli, Scott E Kasner, Francis E Marchlinski, Rajat Deo
BACKGROUND: Long-term rhythm monitoring to detect atrial fibrillation (AF) following a cryptogenic stroke (CS) is well established. However, the burden of organized atrial arrhythmias in this population is not well defined. OBJECTIVE: The purpose of this study was to assess the incidence and risk factors for organized atrial arrhythmias in patients with CS. METHODS: We evaluated all patients with CS who received an insertable cardiac monitor (ICM) between October 2014 and April 2020...
January 2024: Heart rhythm O2
#13
JOURNAL ARTICLE
Mohammad Zamani, Forough Ebrahimtabar, Shaghayegh Alizadeh-Tabari, Scott E Kasner, Mitchell S V Elkind, Ashwin N Ananthakrishnan, Tenzin Choden, David T Rubin, Reza Malekzadeh
BACKGROUND: Several studies investigated the risks of neurological conditions in patients with inflammatory bowel disease (IBD), with some variability in findings. We aimed to perform a systematic review and meta-analysis of available evidence to elucidate the association between IBD and the risks of common neurological disorders. METHODS: We conducted a literature search through Embase, PubMed, Scopus, and ProQuest databases from inception to June 30, 2023, to identify cohort studies assessing the risk of developing stroke, all-cause dementia, Parkinson's disease (PD), multiple sclerosis (MS), seizure/epilepsy, and peripheral neuropathy in adult IBD patients compared with non-IBD population...
January 25, 2024: Inflammatory Bowel Diseases
#14
RANDOMIZED CONTROLLED TRIAL
Elizabeth D Thompson, Ryan T Pohlig, Kiersten M McCartney, T George Hornby, Scott E Kasner, Jonathan Raser-Schramm, Allison E Miller, Christopher E Henderson, Henry Wright, Tamara Wright, Darcy S Reisman
BACKGROUND: Physical inactivity in people with chronic stroke profoundly affects daily function and increases recurrent stroke risk and mortality, making physical activity improvements an important target of intervention. We compared the effects of a high-intensity walking intervention (FAST), a step activity monitoring behavioral intervention (SAM), or a combined intervention (FAST+SAM) on physical activity (ie, steps/day). We hypothesized the combined intervention would yield the greatest increase in steps/day...
January 2024: Stroke; a Journal of Cerebral Circulation
#15
RANDOMIZED CONTROLLED TRIAL
Mukul Sharma, Carlos A Molina, Kazunori Toyoda, Daniel Bereczki, Shrikant I Bangdiwala, Scott E Kasner, Helmi L Lutsep, Georgios Tsivgoulis, George Ntaios, Anna Czlonkowska, Ashfaq Shuaib, Pierre Amarenco, Matthias Endres, Byung-Woo Yoon, David Tanne, Danilo Toni, Laetitia Yperzeele, Paul von Weitzel-Mudersbach, Gisele Sampaio Silva, Alvaro Avezum, Jesse Dawson, Daniel Strbian, Turgut Tatlisumak, Jens Eckstein, Sebastián F Ameriso, Joerg R Weber, Else Charlotte Sandset, Nana Goar Pogosova, Pablo M Lavados, Antonio Arauz, David Gailani, Hans-Christoph Diener, Richard A Bernstein, Charlotte Cordonnier, Anja Kahl, Grigor Abelian, Mark Donovan, Chahin Pachai, Danshi Li, Graeme J Hankey
BACKGROUND: People with factor XI deficiency have lower rates of ischaemic stroke than the general population and infrequent spontaneous bleeding, suggesting that factor XI has a more important role in thrombosis than in haemostasis. Milvexian, an oral small-molecule inhibitor of activated factor XI, added to standard antiplatelet therapy, might reduce the risk of non-cardioembolic ischaemic stroke without increasing the risk of bleeding. We aimed to estimate the dose-response of milvexian for recurrent ischaemic cerebral events and major bleeding in patients with recent ischaemic stroke or transient ischaemic attack (TIA)...
January 2024: Lancet Neurology
#16
JOURNAL ARTICLE
Yu Sakai, Quy Cao, Jeremy Rubin, Jens Witsch, Dan Cohen-Addad, Katyucia de Macedo Rodrigues, Maria Begoña Coco-Martin, Pouyan Pasyar, Jesús Juega, Zhaoyang Fan, Scott E Kasner, Brett L Cucchiara, Jae W Song
BACKGROUND: Complex aortic plaque (CAP) is a potential embolic source in patients with cryptogenic stroke (CS). We review CAP imaging criteria for transesophageal echocardiogram (TEE), computed tomography angiography (CTA), and magnetic resonance imaging and calculate CAP prevalence in patients with acute CS. METHODS AND RESULTS: PubMed and EMBASE databases were searched up to December 2022 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline...
December 5, 2023: Journal of the American Heart Association
#17
JOURNAL ARTICLE
Nishant K Mishra, Patrick Kwan, Tomotaka Tanaka, Katharina S Sunnerhagen, Jesse Dawson, Yize Zhao, Shubham Misra, Selena Wang, Vijay K Sharma, Rajarshi Mazumder, Melissa C Funaro, Masafumi Ihara, John-Paul Nicolo, David S Liebeskind, Clarissa L Yasuda, Fernando Cendes, Terence J Quinn, Zongyuan Ge, Fabien Scalzo, Johan Zelano, Scott E Kasner
INTRODUCTION: Despite significant advances in managing acute stroke and reducing stroke mortality, preventing complications like post-stroke epilepsy (PSE) has seen limited progress. PSE research has been scattered worldwide with varying methodologies and data reporting. To address this, we established the International Post-stroke Epilepsy Research Consortium (IPSERC) to integrate global PSE research efforts. This protocol outlines an individual patient data meta-analysis (IPD-MA) to determine outcomes in patients with post-stroke seizures (PSS) and develop/validate PSE prediction models, comparing them with existing models...
November 15, 2023: BMJ Open
#18
JOURNAL ARTICLE
Mohammad Hossein Abbasi, Ali Eltatawy, Steven R Messé, Ashkan Mowla, Charles J Prestigiacomo, Matthew S Smith, Michela Rosso, Scott E Kasner, Peyman Shirani
OBJECTIVES: Thrombectomy improves outcomes in patients with basilar artery (BA) occlusion. We hypothesized that the anatomic configuration of the BA bifurcation, classified as T- or Y-shaped, may impact the outcome as a T-shaped BA would involve more deep penetrating arteries of the midbrain and thalamus. MATERIALS AND METHODS: In this 2-center retrospective cohort study, we included patients with stroke due to distal BA occlusion and performed blinded classification of their BA distal bifurcation as either T- or Y-shaped...
November 2, 2023: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#19
JOURNAL ARTICLE
Christopher G Favilla, Rodrigo M Forti, Sarah Carter, W Andrew Kofke, Scott E Kasner, Wesley B Baker, Arjun G Yodh, Steven R Messé, Stephanie Cummings, David K Kung, Jan Karl Burkhardt, Omar A Choudhri, Bryan Pukenas, Visish M Srinivasan, Robert W Hurst, John A Detre
BACKGROUND: Endovascular therapy (EVT) has revolutionized the treatment of acute stroke, but large vessel recanalization does not always result in tissue-level reperfusion. Cerebral blood flow (CBF) is not routinely monitored during EVT. We aimed to leverage diffuse correlation spectroscopy (DCS), a novel transcranial optical imaging technique, to assess the relationship between microvascular CBF and post-EVT outcomes. METHODS: Frontal lobe CBF was monitored by DCS in 40 patients undergoing EVT...
October 28, 2023: Journal of Neurointerventional Surgery
#20
JOURNAL ARTICLE
Michela Rosso, Srinath Ramaswamy, Nino Kvantaliani, Yohannes Mulatu, Jessica N Little, Izabela Marczak, Ankita Brahmaroutu, Rajat Deo, Jennifer Lewey, Steven R Messé, Brett L Cucchiara, Steven R Levine, Scott E Kasner
Background Cardiovascular complications after acute ischemic stroke (AIS) can be related to chronic/comorbid cardiac conditions or acute disruption of the brain-heart autonomic axis (stroke-heart syndrome). Women are known to be more vulnerable to certain stress-induced cardiac complications, such as Takotsubo cardiomyopathy. We investigated sex differences in cardiac troponin (cTn) elevation, cardiac events, and outcomes after AIS. Methods and Results We retrospectively analyzed consecutive patients with AIS from 5 stroke centers...
October 18, 2023: Journal of the American Heart Association
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
