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https://www.readbyqxmd.com/read/28100267/a-bibliometric-analysis-of-two-decades-of-aromatherapy-research
#1
Malcolm Koo
BACKGROUND: Quantitative data are lacking on the profile of published research in aromatherapy. The objective of the study was to investigate the profile of original and review articles under the topic aromatherapy using bibliometric analysis. METHODS: Articles on aromatherapy, published between 1995 and 2014, were retrieved from the Science Citation Index-Expanded database from the Web of Science. The records extracted were analyzed for citation characteristics, including the distribution of publication years, languages, countries or regions, journals, articles, and authors using HistCite 12...
January 18, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28088457/preformulation-characterization-stabilization-and-formulation-design-for-the-acrylodan-labeled-glucose-binding-protein-sm4-ac
#2
Neha Sahni, Rajoshi Chaudhuri, John M Hickey, Prakash Manikwar, Ajit D'Souza, Andrew Metters, Sangeeta B Joshi, C Russell Middaugh, David B Volkin
This study describes the physicochemical characterization, stabilization and formulation design of SM4-AC, an acrylodan labeled glucose/galactose binding protein for use in a continuous glucose monitoring device. The physical stability profile of SM4-AC as a function of pH and temperature was monitored using a combination of biophysical techniques and the resulting physical stability profile was visualized using an empirical phase diagram. Forced degradation chemical stability studies (Asn deamidation, Met oxidation) of SM4-AC were performed using a combination of capillary isoelectric focusing (cIEF), peptide mapping and reversed phase high performance liquid chromatography (RP-HPLC)...
January 11, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28078194/trauma-exposed-latina-immigrants-networks-a-social-network-analysis-approach
#3
Alejandra Hurtado-de-Mendoza, Adriana Serrano, Felisa A Gonzales, Nicole C Fernandez, Mark Cabling, Stacey Kaltman
OBJECTIVE: Trauma exposure among Latina immigrants is common. Social support networks can buffer the impact of trauma on mental health. This study characterizes the social networks of trauma-exposed Latina immigrants using a social network analysis perspective. METHODS: In 2011-2012 a convenience sample (n=28) of Latina immigrants with trauma exposure and presumptive depression or posttraumatic stress disorder was recruited from a community clinic in Washington DC...
November 2016: Journal of Latina/o Psychology
https://www.readbyqxmd.com/read/28077720/local-circuits-of-v1-layer-4b-neurons-projecting-to-v2-thick-stripes-define-distinct-cell-classes-and-avoid-cytochrome-oxidase-blobs
#4
Jeff Yarch, Frederick Federer, Alessandra Angelucci
: Decades of anatomical studies on the primate primary visual cortex (V1) have led to a detailed diagram of V1 intrinsic circuitry, but this diagram lacks information about the output targets of V1 cells. Understanding how V1 local processing relates to downstream processing requires identification of neuronal populations defined by their output targets. In primates, V1 layers (L)2/3 and 4B send segregated projections to distinct cytochrome oxidase (CO) stripes in area V2: neurons in CO blob columns project to thin stripes while neurons outside blob columns project to thick and pale stripes, suggesting functional specialization of V1-to-V2 CO streams...
January 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28035814/sbml-diff-a-tool-for-visually-comparing-sbml-models-in-synthetic-biology
#5
James Scott-Brown, Antonis Papachristodoulou
We present sbml-diff, a tool that is able to read a model of a biochemical reaction system in SBML format and produce a range of diagrams showing a range of levels of detail. Each diagram type can be used to visualise a single model, or to visually compare two or more models. The default view depicts species as ellipses, reactions as rectangles, rules as parallelograms, and events as diamonds. A cartoon view replaces the symbols used for reactions based on the associated SBO term (if present). An abstract view represents species as ellipses, and draws edges between these to indicate whether a species increases or decreases the production or degradation of another species...
December 30, 2016: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28011779/cerebroviz-an-r-package-for-anatomical-visu-alization-of-spatiotemporal-brain-data
#6
Ethan Bahl, Tanner Koomar, Jacob J Michaelson
: Spatiotemporal transcriptomic profiling has provided valuable insight into the patterning of gene expression throughout the human brain from early fetal development to adulthood. When combined with prior knowledge of a disease's age at onset and region-specificity, these expression profiles have provided the necessary context to both strengthen putative gene-disease associations and infer new associations. While a wealth of spatiotemporal expression data exists, there are currently no tools available to visualize this data within the anatomical context of the brain, thus limiting the intuitive interpretation of many such findings...
December 22, 2016: Bioinformatics
https://www.readbyqxmd.com/read/27998687/effects-of-applied-stress-ratio-on-the-fatigue-behavior-of-additively-manufactured-porous-biomaterials-under-compressive-loading
#7
Joep de Krijger, Calvin Rans, Brecht Van Hooreweder, Karel Lietaert, Behdad Pouran, Amir A Zadpoor
Additively manufactured (AM) porous metallic biomaterials are considered promising candidates for bone substitution. In particular, AM porous titanium can be designed to exhibit mechanical properties similar to bone. There is some experimental data available in the literature regarding the fatigue behavior of AM porous titanium, but the effect of stress ratio on the fatigue behavior of those materials has not been studied before. In this paper, we study the effect of applied stress ratio on the compression-compression fatigue behavior of selective laser melted porous titanium (Ti-6Al-4V) based on the diamond unit cell...
December 7, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27964719/pathway-collages-personalized-multi-pathway-diagrams
#8
Suzanne Paley, Paul E O'Maille, Daniel Weaver, Peter D Karp
BACKGROUND: Metabolic pathway diagrams are a classical way of visualizing a linked cascade of biochemical reactions. However, to understand some biochemical situations, viewing a single pathway is insufficient, whereas viewing the entire metabolic network results in information overload. How do we enable scientists to rapidly construct personalized multi-pathway diagrams that depict a desired collection of interacting pathways that emphasize particular pathway interactions? RESULTS: We define software for constructing personalized multi-pathway diagrams called pathway-collages using a combination of manual and automatic layouts...
December 13, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/27956095/real-time-visualization-of-the-precipitation-and-phase-behavior-of-octaethylporphyrin-in-lipid-microparticles
#9
Elisa Parra, Pablo Hervella, David Needham
The material properties of micro- and nanoparticles are fundamental for their bulk properties in suspension, like their stability and encapsulation efficiency. A particularly interesting system with potential biomedical applications is the encapsulation of hydrophobic porphyrins into lipid particles and their use as metal atom chelators, where retention and stability are keys for the design process. The overall goal here was to study the solubility, phase behavior and mixing of octaethylporphyrin (OEP) and OEP-Cu chelates with two core materials, triolein (TO) and cholesteryl acetate (CA), as single microparticles...
December 9, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27942090/pathfinder-visual-analysis-of-paths-in-graphs
#10
C Partl, S Gratzl, M Streit, A M Wassermann, H Pfister, D Schmalstieg, A Lex
The analysis of paths in graphs is highly relevant in many domains. Typically, path-related tasks are performed in node-link layouts. Unfortunately, graph layouts often do not scale to the size of many real world networks. Also, many networks are multivariate, i.e., contain rich attribute sets associated with the nodes and edges. These attributes are often critical in judging paths, but directly visualizing attributes in a graph layout exacerbates the scalability problem. In this paper, we present visual analysis solutions dedicated to path-related tasks in large and highly multivariate graphs...
June 2016: Computer Graphics Forum: Journal of the European Association for Computer Graphics
https://www.readbyqxmd.com/read/27923350/coneva-a-toolbox-for-comprehensive-assessment-of-protein-contacts
#11
Badri Adhikari, Jackson Nowotny, Debswapna Bhattacharya, Jie Hou, Jianlin Cheng
BACKGROUND: In recent years, successful contact prediction methods and contact-guided ab initio protein structure prediction methods have highlighted the importance of incorporating contact information into protein structure prediction methods. It is also observed that for almost all globular proteins, the quality of contact prediction dictates the accuracy of structure prediction. Hence, like many existing evaluation measures for evaluating 3D protein models, various measures are currently used to evaluate predicted contacts, with the most popular ones being precision, coverage and distance distribution score (Xd)...
December 7, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/27918598/sighted-and-visually-impaired-students-perspectives-of-illustrations-diagrams-and-drawings-in-school-science
#12
Celia McDonald, Susan Rodrigues
Background In this paper we report on the views of students with and without visual impairments on the use of illustrations, diagrams and drawings (IDD) in science lessons. Method Our findings are based on data gathered through a brief questionnaire completed by a convenience sample of students prior to trialling new resource material. The questionnaire sought to understand the students' views about using IDD in science lessons. The classes involved in the study included one class from a primary school, five classes from a secondary school and one class from a school for visually impaired students...
2016: Wellcome Open Res
https://www.readbyqxmd.com/read/27913586/local-circuits-of-v1-layer-4b-neurons-projecting-to-v2-thick-stripes-define-distinct-cell-classes-and-avoid-cytochrome-oxidase-blobs
#13
Jeff Yarch, Frederick Federer, Alessandra Angelucci
: Decades of anatomical studies on the primate primary visual cortex (V1) have led to a detailed diagram of V1 intrinsic circuitry, but this diagram lacks information about the output targets of V1 cells. Understanding how V1 local processing relates to downstream processing requires identification of neuronal populations defined by their output targets. In primates, V1 layers (L)2/3 and 4B send segregated projections to distinct cytochrome oxidase (CO) stripes in area V2: neurons in CO blob-columns project to thin stripes, and those outside blob columns to thick and pale stripes, suggesting functional specialization of V1-to-V2 CO streams...
December 2, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27899612/ymdb-2-0-a-significantly-expanded-version-of-the-yeast-metabolome-database
#14
Miguel Ramirez-Gaona, Ana Marcu, Allison Pon, An Chi Guo, Tanvir Sajed, Noah A Wishart, Naama Karu, Yannick Djoumbou Feunang, David Arndt, David S Wishart
YMDB or the Yeast Metabolome Database (http://www.ymdb.ca/) is a comprehensive database containing extensive information on the genome and metabolome of Saccharomyces cerevisiae Initially released in 2012, the YMDB has gone through a significant expansion and a number of improvements over the past 4 years. This manuscript describes the most recent version of YMDB (YMDB 2.0). More specifically, it provides an updated description of the database that was previously described in the 2012 NAR Database Issue and it details many of the additions and improvements made to the YMDB over that time...
January 4, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/27896435/course-of-pelvic-lift-during-total-hip-arthroplasty
#15
Steffen Brodt, Dimitri Nowack, Linda Krakow, Christoph Windisch, Georg Matziolis
INTRODUCTION: The position of the cup makes a major contribution to the success of total hip arthroplasty (THA). In conventional implantation of the prosthesis without navigation, the surgeon relies on the spatial position of the pelvis. However, iatrogenic manipulation of the pelvis during different surgical steps constantly changes the position of the pelvis during the operation. The position of the pelvis is substantial for the correct placement of the cup. The objective of this study was to investigate and visualize the course of this pelvic lift and correlate it to certain surgical steps...
November 28, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27893370/network-visualization-as-a-higher-order-visual-analysis-tool
#16
Tim Dwyer
The transformation of data into visuals that are as effective and engaging as possible for compelling presentation is an emerging topic in information visualization research. With this goal in mind, several data-analysis system approaches offer a higher-order network visualization that map insights rather than raw data. Knowledge visualization or externalization in the form of small, focused diagrams can communicate insights as well as help analysts structure their reasoning process.
November 2016: IEEE Computer Graphics and Applications
https://www.readbyqxmd.com/read/27886450/comprehending-3d-diagrams-sketching-to-support-spatial-reasoning
#17
Kristin M Gagnier, Kinnari Atit, Carol J Ormand, Thomas F Shipley
Science, technology, engineering, and mathematics (STEM) disciplines commonly illustrate 3D relationships in diagrams, yet these are often challenging for students. Failing to understand diagrams can hinder success in STEM because scientific practice requires understanding and creating diagrammatic representations. We explore a new approach to improving student understanding of diagrams that convey 3D relations that is based on students generating their own predictive diagrams. Participants' comprehension of 3D spatial diagrams was measured in a pre- and post-design where students selected the correct 2D slice through 3D geologic block diagrams...
November 25, 2016: Topics in Cognitive Science
https://www.readbyqxmd.com/read/27878315/a-plasmonic-elisa-for-the-naked-eye-detection-of-chromium-ions-in-water-samples
#18
Cuize Yao, Shiting Yu, Xiuqing Li, Ze Wu, Jiajie Liang, Qiangqiang Fu, Wei Xiao, Tianjiu Jiang, Yong Tang
Here, we describe the development of a triangular silver nanoprism (AgNPR) etching-based plasmonic ELISA for the colorimetric determination of Cr(III) levels in environmental water samples. This involved the creation of a novel signal generation system (substrate reaction solution) for a competitive ELISA in which hydrogen peroxide (H2O2) is used to etch triangular AgNPRs, inducing a change in color. This is achieved by controlling the H2O2 concentration that remains after degradation by catalase, which is conjugated to the secondary antibody of the ELISA...
November 22, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27875178/optimizing-hierarchical-visualizations-with-the-minimum-description-length-principle
#19
Rafael Veras, Christopher Collins
In this paper we examine how the Minimum Description Length (MDL) principle can be used to efficiently select aggregated views of hierarchical datasets that feature a good balance between clutter and information. We present MDL formulae for generating uneven tree cuts tailored to treemap and sunburst diagrams, taking into account the available display space and information content of the data. We present the results of a proof-of-concept implementation. In addition, we demonstrate how such tree cuts can be used to enhance drill-down interaction in hierarchical visualizations by implementing our approach in an existing visualization tool...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27875177/visualizing-social-media-content-with-sententree
#20
Mengdie Hu, Krist Wongsuphasawat, John Stasko
We introduce SentenTree, a novel technique for visualizing the content of unstructured social media text. SentenTree displays frequent sentence patterns abstracted from a corpus of social media posts. The technique employs design ideas from word clouds and the Word Tree, but overcomes a number of limitations of both those visualizations. SentenTree displays a node-link diagram where nodes are words and links indicate word co-occurrence within the same sentence. The spatial arrangement of nodes gives cues to the syntactic ordering of words while the size of nodes gives cues to their frequency of occurrence...
January 2017: IEEE Transactions on Visualization and Computer Graphics
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