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https://www.readbyqxmd.com/read/28429909/association-between-maternal-vitamin-d-status-during-pregnancy-and-offspring-cognitive-function-during-childhood-and-adolescence
#1
Sargoor R Veena, Ghattu V Krishnaveni, Krishnamachari Srinivasan, Kotrangada P Thajna, Bhavya G Hegde, Catharine R Gale, Caroline Hd Fall
BACKGROUND AND OBJECTIVES: Animal studies have demonstrated poor cognitive outcomes in offspring in relation to maternal vitamin D deficiency before and/or during pregnancy. Human studies linking maternal vitamin D status during pregnancy with offspring cognitive function are limited. We aimed to test the hypothesis that lower maternal vitamin D status during pregnancy is associated with poor offspring cognitive ability in an Indian population. METHODS AND STUDY DESIGN: Cognitive function was assessed in children from the Mysore Parthenon birth cohort during childhood (age 9-10 years; n=468) and adolescence (age 13-14 years; n=472) using 3 core tests from the Kaufman Assessment Battery for children and additional tests measuring learning, long-term retrieval/ storage, short-term memory, reasoning, verbal fluency, visuo-spatial ability, and attention and concentration...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28424259/maternal-vitamin-d-insufficiency-early-in-pregnancy-is-associated-with-increased-risk-of-preterm-birth-in-ethnic-minority-women-in-canada
#2
Negar Tabatabaei, Nathalie Auger, Catherine M Herba, Shuqin Wei, Catherine Allard, Guy D Fink, William D Fraser
Background: Maternal vitamin D insufficiency (plasma 25-hydroxyvitamin D [25(OH)D] <75 nmol/L) may play a role in ethnic disparities in rates of preterm and spontaneous preterm births.Objective: We explored the relation between maternal plasma 25(OH)D concentration in the first trimester (8-14 wk of gestation) and the risk of preterm and spontaneous preterm births (<37 wk of gestation) by ethnicity.Methods: We designed a case-control study that included 120 cases of preterm birth (<37 wk of gestation) and 360 term controls (≥37 wk of gestation) of singleton pregnancies from the 3D cohort, a multicenter study in 2456 pregnant women in Quebec, Canada...
April 19, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28422514/vitamin-c-prevents-offspring-dna-methylation-changes-associated-with-maternal-smoking-in-pregnancy
#3
Lyndsey E Shorey-Kendrick, Cindy T McEvoy, Betsy Ferguson, Julja Burchard, Byung S Park, Lina Gao, Brittany H Vuylsteke, Kristin F Milner, Cynthia D Morris, Eliot R Spindel
BACKGROUND: Infants whose mothers smoked during pregnancy demonstrate lifelong decreases in pulmonary function. DNA methylation changes associated with maternal smoking during pregnancy have been described in placenta and cord blood at delivery, in fetal lung, and in buccal epithelium and blood during childhood. We recently demonstrated in a randomized clinical trial (NCT00632476) that vitamin C supplementation to pregnant smokers can lessen the impact of maternal smoking on offspring pulmonary function and decrease the incidence of wheeze at one year of age...
April 19, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28421711/vitamin-d-status-of-white-pregnant-women-and-infants-at-birth-and-4%C3%A2-months-in-north-west-england-a-cohort-study
#4
A J B Emmerson, K Dockery, M Z Mughal, S A Roberts, C L Tower, J L Berry
The prevalence of vitamin D deficiency in pregnant white-skinned women (WSW) and their infants has not been investigated at northern latitudes in a developed county. A 2-year observational cohort study was undertaken in the North West of England to determine 25-hydroxyvitamin D (25OHD) levels in WSW and their infants during pregnancy and 4 months postdelivery and to explore factors associated with these levels. Nutritional and lifestyle questionnaires were completed and 25OHD levels measured at 28 weeks and 4 months postdelivery...
April 18, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28415531/new-synthesis-of-poly-ortho-methoxyaniline-nanostructures-and-its-application-to-construct-modified-multi-wall-carbon-nanotube-graphite-paste-electrode-for-simultaneous-determination-of-uric-acid-and-folic-acid
#5
Hossein Rajabi, Meissam Noroozifar
Uric acid (UA) and folic acid (FA) are compounds of biomedical interest. In humans, about 70% of daily uric acid disposal occurs via the kidneys, and in 5-25% of humans, impaired renal (kidney) excretion leads to hyperuricemia. Folate is another form folic acid of which is known as, is one of the B vitamins. It is used as a supplement by women to prevent neural tube defects developing during pregnancy. Polyortho-methoxyaniline nanostructures (POMANS) was synthesized with a new two phase (organic-water) synthesis method...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28411961/nutrition-in-the-first-1000-days-and-respiratory-health-a-descriptive-review-of-the-last-five-years-literature
#6
REVIEW
E Verduci, A Martelli, V L Miniello, M Landi, B Mariani, M Brambilla, L Diaferio, D G Peroni
The aim of this paper is to discuss the current evidence regarding short and long-term health respiratory effects of nutrients and dietary patterns during the first 1000 days from conception. Population of interest included children from birth to two years and their mothers (during pregnancy and lactation). Studies were searched on MEDLINE® and Cochrane database, inserting individually and using the Boolean ANDs and ORs, 'nutrients', 'micronutrients', 'LC-PUFA', 'Mediterranean Diet', 'human milk', 'complementary food', 'pregnancy', 'respiratory disease', 'pulmonary disease', 'asthma', 'epigenetics', 'first 1000 days', 'maternal diet' and 'respiratory health'...
April 12, 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28408241/maternal-retinoids-increase-pdgfr%C3%AE-progenitor-population-and-beige-adipogenesis-in-progeny-by-stimulating-vascular-development
#7
Bo Wang, Xing Fu, Xingwei Liang, Zhixiu Wang, Qiyuan Yang, Tiande Zou, Wei Nie, Junxing Zhao, Pengfei Gao, Mei-Jun Zhu, Jeanene M de Avila, Joseph Maricelli, Buel D Rodgers, Min Du
Maternal vitamin A intake varies but its impact on offspring metabolic health is unknown. Here we found that maternal vitamin A or retinoic acid (RA) administration expanded PDGFRα(+) adipose progenitor population in progeny, accompanied by increased blood vessel density and enhanced brown-like (beige) phenotype in adipose tissue, protecting offspring from obesity. Blockage of retinoic acid signaling by either BMS493 or negative RA receptor (RARαDN) over-expression abolished the increase in blood vessel density, adipose progenitor population, and beige adipogenesis stimulated by RA...
April 4, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28403955/french-prenatal-vitamin-d-recommended-supplementation-enough-or-not
#8
P-F Ceccaldi, H Pejoan, N Breau, D Diallo, G Ducarme, O Poujade, C Davitian, D Luton
OBJECTIVE: To determine the impact of current recommended vitamin D prenatal supplementation on blood cord 25(OH)D level in a French cohort and to determine population at risk of higher needs. DESIGN AND SETTING: An observational prospective study was conducted in teaching hospital including two large groups of newborns, one born after summer and another after winter period. PATIENTS AND METHODS: Three hundred and ninety-nine mother/newborns pairs were enrolled and blood cord results were available for 225 newborns in the post-summer group and 174 newborns in the post-winter group...
January 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28403948/association-between-early-pregnancy-vitamin-d-status-and-changes-in-serum-lipid-profiles-throughout-pregnancy
#9
Jaqueline Lepsch, Ilana Eshriqui, Dayana Rodrigues Farias, Juliana S Vaz, Amanda C Cunha Figueiredo, Amanda Rodrigues Amorim Adegboye, Alex Brito, Rana Mokhtar, Lindsay H Allen, Michael F Holick, Gilberto Kac
OBJECTIVE: To evaluate the associations between first trimester 25-hydroxyvitamin D [25(OH)D] status and changes in high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), total cholesterol (TC), triglyceride (TG) concentrations, TG/HDL-c, and TC/HDL-c ratios throughout pregnancy. We hypothesized that first trimester 25(OH)D inadequacy is associated with lower concentrations of HDL-c and higher LDL-c, TC, TG, TG/HDL-c, and TC/HDL-c ratios throughout pregnancy...
May 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28402324/vitamin-b12-status-in-pregnant-women-and-their-infants-in-south-india
#10
J L Finkelstein, A V Kurpad, T Thomas, K Srinivasan, C Duggan
BACKGROUND/OBJECTIVES: Vitamin B12 deficiency during pregnancy has been associated with increased risk of adverse perinatal outcomes. However, few studies have investigated the burden and determinants of vitamin B12 status in young infants. This study was conducted to determine the associations between maternal and infant vitamin B12 status. SUBJECTS/METHODS: Pregnant women participating in a vitamin B12 supplementation trial in Bangalore, India, were randomized to receive vitamin B12 (50 μg) or placebo supplementation daily during pregnancy through 6 weeks postpartum...
April 12, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28401798/most-frequently-reported-prescription-medications-and-supplements-in-couples-planning-pregnancy-the-life-study
#11
Kristin Palmsten, Katrina F Flores, Christina D Chambers, Lauren A Weiss, Rajeshwari Sundaram, Germaine M Buck Louis
OBJECTIVE: To identify frequently reported prescription medications and supplements among couples planning pregnancy because there is a lack of descriptive information on these agents in women and men who are trying to conceive. METHODS: Five hundred one couples enrolled in the Longitudinal Study of Infertility and the Environment, which took place between 2005 and 2009. Participants reported prescription medications as well as prescription and over-the-counter supplements used through interviews at study enrollment and through daily dairies during the 12-month follow-up...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28396154/nutrition-of-black-women-during-pregnancy
#12
Melissa Myles, Susan Gennaro, Nancy Dubois, Caitlin O'Connor, Kayla Roberts
OBJECTIVE: To examine the consistency and adequacy of nutritional intake in a population of Black women in the second and third trimesters of pregnancy. DESIGN: This was a longitudinal descriptive study. Data were collected from women with low-risk pregnancies at 22- to 24-week prenatal visits and two subsequent visits. SETTING: Participants were recruited from urban prenatal clinics in one city in the Northeastern United States. PARTICIPANTS: Pregnant women who self-identified as Black (N = 195)...
April 7, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28395421/-research-on-the-correlation-and-regulation-of-bone-metabolism-related-biochemical-indexes-in-different-gestational-ages
#13
X H Xi, X L Guo, J R Zhang, R Su, T T Ma, J M Ma, L X Wang
Objective: To investigate the correlation and metabolic characteristics of the growth hormone (GH) and other bone metabolism related biochemical markers in pregnancy women serum. Methods: Determination of GH, 25 hydroxy vitamin D(25(OH)D), osteocalcin n-terminal fragments (N-MID), total propeptide of type 1 procollagen (TP1NP) and alkaline phosphatase (ALP) levels in different gestation women serum, the experimental group involving 75 cases of early pregnancy women(11-14 weeks), 135 cases of pregnancy women(15-21 weeks), 62 cases of late pregnancy women(31-40 weeks) and 28 cases of postpartum women(1-3 days)...
April 4, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28394826/osteoporosis-in-premenopausal-women
#14
Bente L Langdahl
PURPOSE OF REVIEW: The scope of this review was to review the newest developments in the context of the existing knowledge on premenopausal bone fragility. Fragility fractures are common in postmenopausal women and men and diagnostic criteria for osteoporosis have been agreed and multiple pharmacological treatments have been developed over the last 25 years. In premenopausal women, fragility fractures and very low bone mass are uncommon and osteoporosis in premenopausal women has therefore attracted much less interest...
April 7, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28389419/rationale-and-design-of-khuzestan-vitamin-d-deficiency-screening-program-in-pregnancy-a-stratified-randomized-vitamin-d-supplementation-controlled-trial
#15
Maryam Rostami, Fahimeh Ramezani Tehrani, Masoumeh Simbar, Farhad Hosseinpanah, Hamid Alavi Majd
BACKGROUND: Although there have been marked improvements in our understanding of vitamin D functions in different diseases, gaps on its role during pregnancy remain. Due to the lack of consensus on the most accurate marker of vitamin D deficiency during pregnancy and the optimal level of 25-hydroxyvitamin D, 25(OH)D, for its definition, vitamin D deficiency assessment during pregnancy is a complicated process. Besides, the optimal protocol for treatment of hypovitaminosis D and its effect on maternal and neonatal outcomes are still unclear...
April 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28387884/the-probiotics-in-dentistry-a-narrative-review
#16
A M Pujia, M Costacurta, L Fortunato, G Merra, S Cascapera, M Calvani, S Gratteri
The total number of microbes that colonize the human body is far greater than the number of cells that make it up. In recent years, it has been shown that bacteria play an essential role in the body; in fact, they are essential for the maturation of the intestine, the development and control of the immune system, the development of the brain, the metabolism of macronutrients, the synthesis of vitamins, and the energy balance. Bacteria play an essential role in defense of their territory against the entry of other bacteria that may be pathogenic to health...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28384281/month-of-birth-and-level-of-insolation-as-risk-factors-for-multiple-sclerosis-in-poland
#17
Paweł Dobrakowski, Michał Bogocz, Kamil Cholewa, Mateusz Rajchel, Katarzyna Kapica-Topczewska, Sławomir Wawrzyniak, Halina Bartosik-Psujek, Alina Kułakowska, Dorota Koziarska, Monika Adamczyk-Sowa
INTRODUCTION: Many studies have shown that people born in the spring are at a higher risk of developing multiple sclerosis (MS). This may be associated with lower levels of sun exposure, and consequently, lower levels of vitamin D3 during pregnancy. However, these relationships have not been verified thus far in any countries in Central Europe. OBJECTIVE: The aim of our study was to determine the frequency distribution of births for each calendar month in patients suffering from MS in Poland...
2017: PloS One
https://www.readbyqxmd.com/read/28381340/high-folate-and-low-vitamin-b12-status-during-pregnancy-is-associated-with-gestational-diabetes-mellitus
#18
Jun S Lai, Wei Wei Pang, Shirong Cai, Yung Seng Lee, Jerry K Y Chan, Lynette P C Shek, Fabian K P Yap, Kok Hian Tan, Keith M Godfrey, Rob M van Dam, Yap Seng Chong, Mary F F Chong
BACKGROUND & AIMS: B-vitamins and homocysteine may contribute to the development of gestational diabetes mellitus (GDM), but existing studies are inconsistent. We examined the cross-sectional associations of plasma folate, vitamins B6, B12, and homocysteine concentrations with GDM and glycemia in a sample of multi-ethnic Asian pregnant women. METHODS: Plasma concentrations of folate, vitamins B6, B12, homocysteine and glucose were measured at 26-weeks' gestation in 913 pregnant women...
March 24, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28377269/multivitamin-use-and-adverse-birth-outcomes-in-high-income-countries-a-systematic-review-and-meta-analysis
#19
REVIEW
Hanne T Wolf, Hanne K Hegaard, Lene D Huusom, Anja B Pinborg
BACKGROUND: In high-income countries (HIC), a healthy diet is widely accessible. However, a change towards a poor quality diet with a low nutritional value in HIC has led to an inadequate vitamin intake during pregnancy. OBJECTIVE: We conducted a systematic review and meta-analysis to evaluate the association between multivitamin use among women in HIC and the risk of adverse birth outcomes (preterm birth (PTB) (primary outcome), low birth weight, small-for-gestational age (SGA), stillbirth, neonatal death, perinatal mortality and congenital anomalies without further specification)...
April 1, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28374905/mtor-folate-sensing-links-folate-availability-to-trophoblast-cell-function
#20
Fredrick J Rosario, Theresa L Powell, Thomas Jansson
Folate is a water-soluble B vitamin that is essential for cellular methylation reactions and DNA synthesis and repair. Low maternal folate levels in pregnancy are associated with fetal growth restriction, however the underlying mechanisms are poorly understood. Mechanistic target of rapamycin (mTOR) links nutrient availability to cell growth and function by regulating gene expression and protein translation. Here we show that mTOR functions as a folate sensor in primary human trophoblast (PHT) cells. Folate deficiency in PHT cells caused inhibition of mTOR signalling and decreased the activity of key amino acid transporters...
April 4, 2017: Journal of Physiology
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