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vitamin a pregnancy

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https://www.readbyqxmd.com/read/28635116/maternal-smoking-alcohol-and-caffeine-exposures-and-risk-of-hypospadias
#1
Suzan L Carmichael, Chen Ma, Gary M Shaw
BACKGROUND: We examined the association of hypospadias risk with maternal smoking and consumption of alcohol and caffeine. METHODS: We analyzed data from mothers of 2437 moderate/severe cases and 5472 nonmalformed controls born from 1997 to 2011 who participated in the National Birth Defects Prevention Study (NBDPS). Exposures were assessed by maternal telephone interviews. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs) adjusted for mother's age, parity, race-ethnicity, education, vitamin/mineral supplement intake, obesity, and study center...
June 21, 2017: Birth defects research
https://www.readbyqxmd.com/read/28632934/a-prospective-microbiome-wide-association-study-of-food-sensitization-and-food-allergy-in-early-childhood
#2
Jessica H Savage, Kathleen A Lee-Sarwar, Joanne Sordillo, Supinda Bunyavanich, Yanjiao Zhou, George O'Connor, Megan Sandel, Leonard Bacharier, Robert Zeiger, Erica Sodergren, George M Weinstock, Diane R Gold, Scott T Weiss, Augusto A Litonjua
BACKGROUND: Alterations in the intestinal microbiome are prospectively associated with the development of asthma; less is known regarding the role of microbiome alterations in food allergy development. METHODS: Intestinal microbiome samples were collected at age 3-6 months in children participating in the follow-up phase of an interventional trial of high dose Vitamin D given during pregnancy. At age 3, sensitization to foods (milk, egg, peanut, soy, wheat, walnut) was assessed...
June 20, 2017: Allergy
https://www.readbyqxmd.com/read/28631509/comparison-of-quince-with-vitamin-b6-for-treatment-of-nausea-and-vomiting-in-pregnancy-a-randomised-clinical-trial
#3
Effat Jafari-Dehkordi, Fataneh Hashem-Dabaghian, Fatemeh Aliasl, Jaleh Aliasl, Maryam Taghavi-Shirazi, Omid Sadeghpour, Farnaz Sohrabvand, Bagher Minaei, Roshanak Ghods
This trial was performed to compare quince (Cydonia oblonga) fruit with vitamin B6 on 76 pregnant women with a gestational age of 6-14 weeks and mild-to-moderate nausea and vomiting (NVP) (40 in the quince and 36 in the B6 group). The 'Pregnancy-Unique Quantification of Emesis' (PUQE-24) scale was used to examine the severity of NVP. The quince syrup (1 tablespoon/TDS) or vitamin B6 tablets (20 mg/TDS) were used as intervention for 1 week. The mean (±SD) age was 27.5 (±5.2) years. The score of the PUQE was decreased from 9...
June 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28629584/association-of-vitamin-d-intake-and-serum-levels-with-fertility-results-from-the-lifestyle-and-fertility-study
#4
June L Fung, Terryl J Hartman, Rosemary L Schleicher, Marlene B Goldman
OBJECTIVE: To evaluate the role of vitamin D intake and serum levels on conception of clinical pregnancy and live birth. DESIGN: Prospective cohort study. SETTING: Academic medical centers. PATIENT(S): Healthy, nulliparous women, age 18-39 years, and their male partners. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Clinical pregnancy and live birth were compared between those who did or did not meet the vitamin D estimated average requirement (EAR) intake (10 μg/d) and with serum 25-hydroxyvitamin D (25(OH)D) considered at risk for inadequacy or deficiency (<50 nmol/L) or sufficient (≥50 nmol/L)...
June 16, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28629250/a-comparison-between-the-effects-of-ginger-pyridoxine-vitamin-b6-and-placebo-for-the-treatment-of-the-first-trimester-nausea-and-vomiting-of-pregnancy-nvp
#5
Fatemeh Sharifzadeh, Maryam Kashanian, Jalil Kouhpayehzadeh, Fatemeh Rezaian, Narges Sheikhansari, Nooshin Eshraghi
INTRODUCTION: Nausea and vomiting of pregnancy (NVP) are one of the most common complains of the early pregnancy period and are bothersome for pregnant women. Some prefer to use herbal medicine instead of chemical agents. OBJECTIVE: The purpose of the present study was to compare the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of NVP. METHOD: The study was performed as a triple blind clinical trial on pregnant women suffering mild to moderate NVP between 6-16 weeks of pregnancy...
June 19, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28627837/natural-antioxidant-vitamins-status-in-pregnancies-complicated-with-intrauterine-growth-restriction
#6
Amita K Gadhok, Tarun K Sharma, Maheep Sinha, Rakesh Khunteta, Satish K Vardey, Poonam Sahni, Manisha Sankhla
BACKGROUND: The weight of the infant at birth is a powerful predictor of infant growth and survival and is dependent on maternal health and nutrition during pregnancy. Pregnant women have a defense mechanism against increased oxidative stress composed of antioxidant enzymes and natural antioxidant vitamins like vitamin C and E. Therefore, we evaluated whether differences exist in serum levels of vitamin C and E in pregnant women complicated with intrauterine growth restriction (IUGR)...
May 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28625761/impact-of-vitamin-d-levels-on-ovarian-reserve-and-ovarian-response-to-ovarian-stimulation-in-oocyte-donors
#7
Alberta Maria Fabris, Maria Cruz, Carlos Iglesias, Alberto Pacheco, Azadeh Patel, Jayesh Patel, Human Fatemi, Juan Antonio García-Velasco
Recently, growing interest in vitamin D has emerged from findings that demonstrate a low vitamin D status in populations. Similarly, much interest has been shown in the role that anti-Müllerian hormone (AMH) plays in reproductive physiology. Considerable confusion as to whether vitamin D status is related to ovarian function can be found in the literature. Our retrospective study was performed from June 2014 to April 2015. Oocyte donors were recruited and stimulated under the antagonist protocol with gonadotrophin-releasing hormone (GnRH) agonist to trigger ovulation...
May 19, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28625206/organic-food-consumption-during-pregnancy-and-its-association-with-health-related-characteristics-the-koala-birth-cohort-study
#8
Ana Paula Simões-Wüst, Carolina Moltó-Puigmartí, Eugene Hjm Jansen, Martien Cjm van Dongen, Pieter C Dagnelie, Carel Thijs
OBJECTIVE: To investigate the associations of organic food consumption with maternal pre-pregnancy BMI, hypertension and diabetes in pregnancy, and several blood biomarkers of pregnant women. DESIGN: Prospective cohort study. SETTING: Pregnant women were recruited at midwives' practices and through channels related to consumption of food from organic origin. SUBJECTS: Pregnant women who filled in FFQ and donated a blood sample (n 1339)...
June 19, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28624327/many-tocopherols-one-vitamin-e
#9
REVIEW
Angelo Azzi
Four tocopherols are available in nature and are absorbed with the diet, but only one RRR-α-tocopherol satisfies the criteria of being a vitamin. The biological activity of the different tocopherols studied in the rat by the resorption-gestation test has been inconsistently extrapolated to human beings where the tocopherols have no influence on a successful pregnancy. Diminution of RRR-α-tocopherol intake results in diseases characterized by ataxia, whose pathogenetic mechanism, despite vigorous claims, has not been clarified...
June 17, 2017: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/28622535/vitamin-d-mediates-the-relationship-between-placental-cathelicidin-and-group-b-streptococcus-colonization-during-pregnancy
#10
Christine C Akoh, Eva K Pressman, Corrie M Whisner, Carrie Thomas, Chang Cao, Tera Kent, Elizabeth Cooper, Kimberly O O'Brien
Vitamin D is thought to modulate innate immune responses, and recent studies have highlighted the autocrine and paracrine functions of vitamin D in the placenta. Our objective was to determine the relationship between maternal vitamin D status and placental antimicrobial peptide (AMP) expression in a group of racially and ethnically diverse pregnant adolescents. In this study, 158 pregnant adolescents were recruited from the Rochester Adolescent Maternity Program (RAMP) in Rochester, NY. Maternal serum concentrations of the vitamin D biomarkers, 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH)2D), were measured at mid-gestation (∼26 weeks) and at delivery...
June 6, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/28620575/osteoporosis-management-in-ankylosing-spondylitis
#11
Alicia M Hinze, Grant H Louie
Low bone mineral density (BMD) is increasingly recognized as a common comorbid condition in ankylosing spondylitis (AS). As low BMD increases fracture risk, it is important to identify and treat low BMD in patients with AS who have been shown to be at increased risk for fractures above the population normal. Since low BMD occurs early in disease, we screen during the first year of diagnosis with dual energy x-ray absorptiometry (DXA). If patients are found to have osteoporosis by T-score of less than -2.5 or if their Z-score on DXA is more than two standard deviations below the mean, we initiate therapy with bisphosphonates in males and in females who are not planning any future pregnancies...
December 2016: Current Treatment Options in Rheumatology
https://www.readbyqxmd.com/read/28620423/vitamin-d-in-pregnancy-current-perspectives-and-future-directions
#12
REVIEW
Mairead Kiely, Andrea Hemmingway, Karen M O'Callaghan
As neonatal vitamin D status is determined by circulating maternal 25-hydroxyvitamin D [25(OH)D] concentrations, prevention of maternal vitamin D deficiency during pregnancy is essential for the avoidance of neonatal deficiency. However, a high prevalence of vitamin D deficiency has been extensively reported among gravidae and neonates from ethnic minorities and white populations resident at high latitude. Currently, regulatory authorities recommend vitamin D intakes for pregnant women that are similar to non-pregnant adults of the same age, at 10-15 µg/day (400-600 IU), to meet 25(OH)D thresholds of 25-50 nmol/liter...
June 2017: Therapeutic Advances in Musculoskeletal Disease
https://www.readbyqxmd.com/read/28619429/vitamin-d-and-multiple-sclerosis-an-update
#13
REVIEW
Charles Pierrot-Deseilligny, Jean-Claude Souberbielle
The most recent findings linking exposure to sun and vitamin D insufficiency to multiple sclerosis (MS) are reviewed. Due to insufficient sunshine and changing lifestyles, hypovitaminosis D is widespread in temperate countries. Numerous epidemiological studies have strongly suggested that sunshine and vitamin D insufficiency contributes to MS risk in these countries. Moreover, several large genetic studies in MS patients have recently stated unequivocally that diverse abnormalities involving vitamin D metabolism are related to the risk of the disease...
May 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28618852/low-vitamin-d-is-associated-with-infections-and-proinflammatory-cytokines-during-pregnancy
#14
Christine C Akoh, Eva K Pressman, Elizabeth Cooper, Ruth Anne Queenan, Julie Pillittere, Kimberly O O'Brien
Vitamin D is known to regulate innate and adaptive immune processes at the cellular level, but the role of vitamin D status on associated inflammatory processes across pregnancy is unclear. Our primary objective was to evaluate the relationships between serum biomarkers of inflammation (interleukin [IL]-6, IL-10, tumor necrosis factor [TNF]-α), acute-phase proteins (C-reactive protein and hepcidin) and vitamin D status, 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH)2D), measured across pregnancy and in the neonate at birth...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28615379/daily-consumption-of-lipid-based-nutrient-supplements-containing-250-%C3%AE-g-iodine-does-not-increase-urinary-iodine-concentrations-in-pregnant-and-postpartum-women-in-bangladesh
#15
Malay K Mridha, Susana L Matias, Rina Rani Paul, Sohrab Hussain, Md Showkat Ali Khan, Zakia Siddiqui, Barkat Ullah, Mostofa Sarker, Mokbul Hossain, Rebecca T Young, Charles D Arnold, Kathryn G Dewey
Background: Maternal iodine deficiency during pregnancy and lactation is common in Bangladesh.Objective: We evaluated the effect of lipid-based nutrient supplements for pregnant and lactating women (LNS-PL) on urinary iodine concentration (UIC).Methods: We conducted a cluster-randomized controlled effectiveness trial in which we enrolled 4011 pregnant women at ≤20 gestational weeks. Women in 48 clusters received iron and folic acid (IFA; 60 mg Fe/d + 400 μg folic acid/d) and women in 16 clusters received LNS-PL (20 g/d, 118 kcal) containing 22 vitamins and minerals (including 250 μg I)...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615265/adequacy-of-nutritional-intake-from-food-and-supplements-in-a-cohort-of-pregnant-women-in-qu%C3%A3-bec-canada-the-3d-cohort-study-design-develop-discover
#16
Lise Dubois, Maikol Diasparra, Brigitte Bédard, Cynthia K Colapinto, Bénédicte Fontaine-Bisson, Anne-Sophie Morisset, Richard E Tremblay, William D Fraser
Background: Assessments of the dietary intakes in various populations suggest that pregnant women have difficulty meeting all their nutritional requirements through diet alone. Few large-scale studies have considered both food sources and supplements in assessing the adequacy of nutritional intakes during pregnancy.Objectives: Our study aimed to assess nutritional intakes during pregnancy by examining dietary sources and supplements. It then compared these findings with Dietary Reference Intakes.Design: We conducted a nutrition study in a large pregnancy cohort using a 3-d food record during the second trimester of pregnancy...
June 14, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28614956/interventions-for-treating-hyperemesis-gravidarum-a-cochrane-systematic-review-and-meta-analysis
#17
Rupsa C Boelig, Samantha J Barton, Gabriele Saccone, Anthony J Kelly, Steven J Edwards, Vincenzo Berghella
INTRODUCTION: While nausea and vomiting in early pregnancy are very common, affecting approximately 80% of pregnancies, hyperemesis gravidarum is a severe form affecting 0.3-1.0% of pregnancies. Although hyperemesis gravidarum is rarely a source of mortality, it is a significant source of morbidity. It is one of the most common indications for hospitalization in pregnancy. Beyond the maternal and fetal consequences of malnutrition, the severity of hyperemesis symptoms causes a major psychosocial burden leading to depression, anxiety, and even pregnancy termination...
June 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28612338/nutritional-rickets-and-osteomalacia-in-the-twenty-first-century-revised-concepts-public-health-and-prevention-strategies
#18
REVIEW
Suma Uday, Wolfgang Högler
PURPOSE OF REVIEW: Nutritional rickets and osteomalacia are common in dark-skinned and migrant populations. Their global incidence is rising due to changing population demographics, failing prevention policies and missing implementation strategies. The calcium deprivation spectrum has hypocalcaemic (seizures, tetany and dilated cardiomyopathy) and late hypophosphataemic (rickets, osteomalacia and muscle weakness) complications. This article reviews sustainable prevention strategies and identifies areas for future research...
June 13, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28612095/maternal-fetal-vitamin-d-receptor-polymorphisms-significantly-associated-with-preterm-birth
#19
Talya Rosenfeld, Hagit Salem, Gheona Altarescu, Sorina Grisaru-Granovsky, Aharon Tevet, Ruth Birk
PURPOSE: Preterm birth (PTB) is a complex trait with strong genetic background, whose etiology is not fully understood. It was recently suggested that pregnancy duration is affected by fetal genetic variation even more than by the maternal genome. Vitamin D receptor (VDR) is involved in embryonic implantation and fertility. We studied the association between both maternal and neonatal vitamin D receptor (VDR) genetic variation and PTB. METHODS: Maternal and fetal (umbilical cord) DNA was isolated from Jewish Israeli idiopathic preterm newborns (24-36 weeks, n = 146) and control term newborns (>37 weeks, n = 229)...
June 13, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28608585/effect-of-dietary-conjugated-linoleic-acid-on-vitamin-a-status-of-lactating-rats-and-their-offspring
#20
J O Zeitz, E Most, K Eder
The absorption and metabolism of vitamin A is linked with that of lipids. It is known that conjugated linoleic acid (CLA) affects the lipid metabolism in growing and lactating animals. In the present study, the hypothesis was investigated that dietary CLA influences vitamin A status of lactating rats and their pups during the suckling period. For this purpose, Wistar Han rats were fed either a control diet (control group, n = 14) or a diet containing 0.87% of cis-9, trans-11 and trans-10, cis-12 (1:1) CLA (CLA group, n = 14) during pregnancy and lactation...
June 13, 2017: Journal of Animal Physiology and Animal Nutrition
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