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vitamin a pregnancy

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https://www.readbyqxmd.com/read/29168736/association-between-vitamin-intake-during-pregnancy-and-risk-of-small-for-gestational-age
#1
Inmaculada Salcedo-Bellido, Juan Miguel Martínez-Galiano, Rocío Olmedo-Requena, Juan Mozas-Moreno, Aurora Bueno-Cavanillas, Jose J Jimenez-Moleon, Miguel Delgado-Rodríguez
Pregnancy increases the requirements of certain nutrients, such as vitamins, to provide nutrition for the newborn. The aim was to analyze the association between dietary intake of vitamins during pregnancy and risk of having a small for gestational age (SGA) newborn. A matched case-control study was conducted (518 cases and 518 controls of pregnant women) in Spain. Dietary vitamin intake during pregnancy was assessed using a validated food frequency questionnaire, categorized into quintiles. Odds ratios (ORs) and their 95% confidence intervals (CI) were estimated with conditional regression logistic models...
November 23, 2017: Nutrients
https://www.readbyqxmd.com/read/29165637/a-controlled-study-of-the-effects-of-ferric-carboxymaltose-on-bone-and-haematinic-biomarkers-in-chronic-kidney-disease-and-pregnancy
#2
Louis L Huang, Darren Lee, Stefanie M Troster, Annette B Kent, Matthew A Roberts, Iain C Macdougall, Lawrence P McMahon
Background: Intravenous (IV) iron can modulate fibroblast growth factor 23 (FGF23) concentrations and cause transient but significant hypophosphataemia. However, it is unknown what other markers might be involved, especially in different patient groups. This study aimed to determine changes in bone and haematinic biomarkers following IV ferric carboxymaltose (FCM) and to identify risk factors for hypophosphataemia in pregnant subjects and those with chronic kidney disease (CKD). Methods: Changes in bone [serum FGF23, fractional excretion of phosphate urinary fractional excretion of phosphate (FEPi), serum phosphate and serum vitamin D derivatives] and haematinic [plasma hepcidin, serum ferritin and transferrin saturation (TSAT)] biomarkers after 1 g of IV FCM were followed in iron-deficient pregnant and CKD patients and compared with controls (estimated glomerular filtration rate > 60 mL/min/1...
November 17, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29161966/altered-downstream-target-gene-expression-of-the-placental-vitamin-d-receptor-in-human-idiopathic-fetal-growth-restriction
#3
Thy Ph Nguyen, Hannah Ej Yong, Tejasvy Chollangi, Shaun P Brennecke, Susan J Fisher, Euan M Wallace, Peter R Ebeling, Padma Murthi
Fetal growth restriction (FGR) affects up to 5% of pregnancies and is associated with significant perinatal complications. Maternal deficiency of vitamin D, a secosteroid hormone, is common in FGR-affected pregnancies. We recently demonstrated that decreased expression of the vitamin D receptor (VDR) in idiopathic FGR placentae could impair trophoblast growth. As strict regulation of cell-cycle genes in trophoblast cells is critical for optimal feto-placental growth, we hypothesised that pathologically decreased placental VDR contributes to aberrant regulation of cell-cycle genes...
November 22, 2017: Cell Cycle
https://www.readbyqxmd.com/read/29159790/vitamin-d-supplementation-in-pregnancy-a-survey-of-compliance-with-recommendations
#4
C M Windrim, D A Crosby, K Mitchell, C Brophy, R Mahony, M Higgins
BACKGROUND: Vitamin D deficiency in pregnancy has important maternal and fetal implications, with increased risk of developing gestational diabetes, preeclampsia, preterm birth and small for gestational age birthweight. It is recommended that every pregnant woman should take 5 μg (200 IU) of vitamin D per day during pregnancy and lactation. AIMS: This study aimed to determine the prevalence of women taking vitamin D supplementation and to identify the reasons for patients not taking supplementation within women attending an antenatal clinic in Dublin...
November 20, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29158721/knowledge-of-community-pharmacists-about-the-risks-of-medication-use-during-pregnancy-in-central-region-of-saudi-arabia
#5
Ziyad Alrabiah, Mohamed N Al-Arifi, Sultan M Alghadeer, Syed Wajid, Ali AlQahtani, Naif Almotari, AbdAllh AlHwerani, Salmeen D Babelghaith
Background: Community pharmacists (CPs) are the most accessible health care provider to the public, and they have huge duties to improve medication use especially among the pregnant women in their community. The objective of this study was to evaluate knowledge of CPs about the medication safety during pregnancy. Methods: A prospective cross-sectional survey was carried out over practicing community pharmacists in a capital of Saudi Arabia (SA). Pharmacists were asked about the safety of each medicine during pregnancy...
November 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/29157289/vitamin-c-plus-hydrogel-facilitates-bone-marrow-stromal-cell-mediated-endometrium-regeneration-in-rats
#6
Huan Yang, Su Wu, Ran Feng, Junjiu Huang, Lixiang Liu, Feng Liu, Yuqing Chen
BACKGROUND: Intrauterine adhesion (IUA) is a common uterine cavity disease which can be caused by mechanical damage that may eventually lead to infertility and pregnancy abnormalities. Since the effect of therapeutic drugs appears disappointing, cell therapy has emerged as an alternative choice for endometrium regeneration. The aim of this study is to investigate whether the combination of hydrogel Pluronic F-127 (PF-127), Vitamin C (Vc), and a bone marrow stromal cell (BMSC) mixture could be a feasible strategy to improve the endometrial regeneration in a mechanical damage model of IUA in rats...
November 21, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29157031/early-prenatal-vitamin-d-concentrations-and-social-emotional-development-in-infants
#7
Devika Chawla, Bernard Fuemmeler, Sara Benjamin Neelon, Cathrine Hoyo, Susan Murphy, Julie Daniels
BACKGROUND: Many pregnant women in the USA have suboptimal vitamin D, but the impact on infant development is unclear. Moreover, no pregnancy-specific vitamin D recommendations have been widely accepted. AIMS: Given the ubiquitous expression of vitamin D receptors in the brain, we investigated the association between early prenatal plasma 25-hydroxyvitamin D (25(OH)D) concentrations and children's social and emotional development in the Newborn Epigenetic Study, a prospective study of pregnancies from 2009 to 2011 in Durham, North Carolina, United States of America...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29153679/hypertensive-disorders-of-pregnancy-in-women-with-gestational-diabetes-mellitus-from-rio-de-janeiro-brazil
#8
Luciana Lourenço Gomes Dos Santos da Silva, Cláudia Saunders, Aline Bull Ferreira Campos, Gabriella Pinto Belfort, Patricia de Carvalho Padilha, Rosangela Alves Pereira, Rita Guérios Bornia
Pregnant women with Gestational Diabetes Mellitus (GDM) have a greater chance of developing Hypertensive Disorders of Pregnancy (HDP) by the effect of insulin resistance in nitric oxide action.This study aims to describe factors associated with the development of HDP in pregnant women with GDM, assisted in a public maternity hospital in Rio de Janeiro, Brazil. This is a cross-sectional study including 292 pregnant adult women with GDM assisted at Maternidade Escola of the Universidade Federal do Rio de Janeiro...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29150215/lifestyles-guide-and-glaucoma-ii-diet-supplements-drugs-sleep-pregnancy-and-systemic-hypertension
#9
A Antón-López, J Moreno-Montañés, S Duch-Tuesta, P Corsino Fernández-Vila, J García-Feijoo, E Millá-Griñó, F J Muñoz-Negrete, L Pablo-Júlvez, I Rodríguez-Agirretxe, J L Urcelay-Segura, F Ussa-Herrera, M P Villegas-Pérez
PURPOSE: To establish evidence based guidelines to advise patients on the relationship between habits, diet, certain circumstances, diseases and glaucoma. METHODS: Review of all published articles on glaucoma and sports or other activities. The papers were classified according to the level of scientific evidence based on the Oxford Centre for Evidence-based Medicine classification. RESULTS: The evidence on the relationship between diet or supplements and the incidence or progression of glaucoma is insufficient to make a general recommendation for glaucoma patients...
November 14, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29149263/vitamin-d-and-assisted-reproductive-treatment-outcome-a-systematic-review-and-meta-analysis
#10
Justin Chu, Ioannis Gallos, Aurelio Tobias, Bee Tan, Abey Eapen, Arri Coomarasamy
STUDY QUESTION: Is serum vitamin D associated with live birth rates in women undergoing ART? SUMMARY ANSWER: Women undergoing ART who are replete in vitamin D have a higher live birth rate than women who are vitamin D deficient or insufficient. WHAT IS KNOWN ALREADY: Vitamin D deficiency has been associated with an increased risk of abnormal pregnancy implantation as well as obstetric complications such as pre-eclampsia and fetal growth restriction...
November 15, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29145296/approach-to-the-patient-with-pregnancy-and-lactation-associated-osteoporosis-a-case-report-and-a-review-of-the-literature
#11
Min Zhang, Ping Chen, Bin Li, Juan Du, Ting Pan, Jingyan Chen
RATIONALE: Pregnancy and lactation-associated osteoporosis (PLO) is very rare, but it can cause severe vertebral compression fractures with disabling back pain. Although it is a rare, PLO must be kept in mind in the differential diagnosis in patients presenting with low back pain during or after pregnancy. PATIENT CONCERNS: A 23-year-old woman who suffered from lumbago and fractures in the vertebral column 1 month after delivery. DIAGNOSIS: Pregnancy and lactation-associated osteoporosis...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29137132/maternal-vitamin-d-status-and-the-relationship-with-neonatal-anthropometric-and-childhood-neurodevelopmental-outcomes-results-from-the-seychelles-child-development-nutrition-study
#12
Eamon Laird, Sally W Thurston, Edwin van Wijngaarden, Conrad F Shamlaye, Gary J Myers, Philip W Davidson, Gene E Watson, Emeir M McSorley, Maria S Mulhern, Alison J Yeates, Mary Ward, Helene McNulty, J J Strain
Vitamin D has an important role in early life; however, the optimal vitamin D status during pregnancy is currently unclear. There have been recent calls for pregnant women to maintain circulating 25-hydroxyvitamin D (25(OH)D) concentrations >100 nmol/L for health, yet little is known about the long-term potential benefits or safety of achieving such high maternal 25(OH)D concentrations for infant or child health outcomes. We examined maternal vitamin D status and its associations with infant anthropometric and later childhood neurocognitive outcomes in a mother-child cohort in a sun-rich country near the equator (4...
November 11, 2017: Nutrients
https://www.readbyqxmd.com/read/29137047/massive-neonatal-intracranial-hemorrhage-caused-by-bromadiolone-a-case-report
#13
Mingsheng Ma, Mengqi Zhang, Xiaoyan Tang, Zhenghong Li
RATIONALE: Bromadiolone, often called a super-warfarin, is a potent rodenticide with long half-life. Skin and mucosal bleeding is the most common clinical manifestations of its intoxication. Bromadiolone intoxications in adults and children have been reported, but this phenomenon is rarely seen in fetuses. This paper presents a case of neonate with massive intracranial hemorrhage mediated by bromadiolone intoxication, highlighting that the bromadiolone is potentially lethal to the fetus...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29133192/maternal-micronutrients-omega-3-fatty-acids-and-gene-expression-of-angiogenic-and-inflammatory-markers-in-pregnancy-induced-hypertension-rats
#14
Nisha Kemse, Deepali Sundrani, Anvita Kale, Sadhana Joshi
BACKGROUND AND AIMS: Preeclampsia is a disorder of pregnancy and is associated with inflammation and altered angiogenesis. The present study examines the effect of micronutrient and omega-3 fatty acid supplementation (individual, as well as combined) on genes involved in inflammation and angiogenesis, as well as global DNA methylation levels in a pregnancy induced hypertension (PIH) rat model. METHODS: Pregnant Wistar rats were randomly assigned to six dietary groups: control, PIH (Pregnancy induced hypertension) Induced; PIH Induced with micronutrient supplements with vitamin B12 (PIHB), folate (PIHF), omega-3 fatty acid (PIHO), and combined supplementation (PIHC) (micronutrients and omega-3 fatty acids)...
November 10, 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29132734/role-of-vitamin-e-and-d3-supplementation-in-intra-cytoplasmic-sperm-injection-outcomes-of-women-with-polycystic-ovarian-syndrome-a-double-blinded-randomized-placebo-controlled-trial
#15
Farnaz Fatemi, Afsaneh Mohammadzadeh, Mohammad Reza Sadeghi, Mohammad Mehdi Akhondi, Shayan Mohammadmoradi, Koorosh Kamali, Nicknam Lackpour, Sheida Jouhari, Simin Zafadoust, Sara Mokhtar, Ladan Giahi
BACKGROUND & AIMS: Ovulation induction has been proven to impose oxidative stress during ICSI treatment cycle. Also, data indicates that PCOS women show higher oxidative markers. Available data are not convincing about which antioxidant supplements have the potential to overcome oxidative stress in PCOS subjects. The aim of this trial was to investigate the possible role of combined vitamin E and D supplementation in the ICSI outcomes (oocyte number and quality, embryo number and quality, pregnancy rate) of PCOS subjects...
April 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29128970/cord-serum%C3%A2-25-hydroxyvitamin-d-is-not-associated-with-cranial-anthropometrics-in-infants-up-to-6%C3%A2-months-of-age-an-odense-child-cohort-study
#16
Sissil Egge, Nikolas Christensen, Sine Lykkedegn, Tina Kold Jensen, Henrik Thybo Christesen
Skull changes are poorly described in vitamin D insufficiency [serum 25-hydroxyvitamin D (s-25(OH)D) 25-50 nmol/L]. We aimed to investigate factors associated with cranial anthropometrics in infants, especially s-25(OH)D. In infants 2.5-6 months old from the Odense Child Cohort, associations between cord and pregnancy s-25(OH)D and anterior fontanel area (n = 765), head circumference (HC, n = 1776) and head shape (n = 1527) were investigated along with other factors. Age was corrected for preterm birth...
November 11, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29128634/vitamin-d-receptor-vdr-polymorphisms-are-associated-to-spontaneous-preterm-birth-and-maternal-aspects
#17
N R Javorski, C A D Lima, L V C Silva, S Crovella, J de Azêvedo Silva
Preterm birth (PTB) is featured by less than 37weeks of gestational age or fewer than 259days since the first day from the last menstrual period. Complications of PTB are the major cause of neonatal deaths, several factors are linked to PTB increased risk including immunological and genetics. Vitamin D plays an important role in immune response modulation and its action occurs through the vitamin D receptor (VDR), which recently has been described as overexpressed in human placenta during the pregnancy. Herein we assessed two single nucleotide polymorphisms (SNPs) FokI (rs2228570 A>G) and Cdx-2 (rs11568820 T>C), within VDR, using TaqMan fluorogenic probes, and differential susceptibility to SPTB...
November 8, 2017: Gene
https://www.readbyqxmd.com/read/29127865/which-information-on-women-s-issues-in-epilepsy-does-a-community-pharmacist-need-to-know-a-delphi-consensus-study
#18
Ramzi Shawahna
OBJECTIVE: The aim of this study was to develop and achieve consensus on a core list of important knowledge items that community pharmacists should know on women's issues in epilepsy. METHODS: This was a consensual study using a modified Delphi technique. Knowledge items were collected from the literature and from nine key contacts who were interviewed on their views on what information community pharmacists should have on women's issues in epilepsy. More knowledge items were suggested by five researchers with interest in women's issues who were contacted to rate and comment on the knowledge items collected...
November 8, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29126319/effects-of-vitamin-d-supplementation-on-semen-quality-reproductive-hormones-and-live-birth-rate-a-randomized-clinical-trial
#19
Martin Blomberg Jensen, Jacob Gerner Lawaetz, Jørgen Holm Petersen, Anders Juul, Niels Jørgensen
Context: Animal models and cross-sectional cohort studies have suggested a beneficial role for vitamin D in male reproduction. Objective: Determine the effect of vitamin D and calcium supplementation on semen quality in infertile men with serum 25-hydroxyvitamin-D (25OHD)≤ 50 nmol/l. Design: A single centre, triple-blinded, randomized clinical trial. Participants: 1427 infertile men were screened to include 330. 1002 men did not meet inclusion criteria and 95 did not wish to participate...
November 3, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29122468/an-intronic-variation-in-slc52a1-causes-exon-skipping-and-transient-riboflavin-responsive-multiple-acyl-coa-dehydrogenation-deficiency
#20
Signe Mosegaard, Gitte Hoffmann Bruun, Karen Freund Flyvbjerg, Yngve Thomas Bliksrud, Niels Gregersen, Maja Dembic, Ellen Annexstad, Trine Tangeraas, Rikke Katrine Jentoft Olsen, Brage S Andresen
Vitamin B2, riboflavin is essential for cellular function, as it participates in a diversity of redox reactions central to human metabolism, through its role as precursor for the cofactors flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are electron carriers. The electron transfer flavoprotein (ETF) and its dehydrogenase (ETFDH), uses FAD as cofactor. The ETF and ETFDH are forming the electron transport pathway for many mitochondrial flavoprotein dehydrogenases involved in fatty acid, amino acid and choline metabolism...
November 2, 2017: Molecular Genetics and Metabolism
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