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Visualization of Qualitative Research

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https://www.readbyqxmd.com/read/28108479/study-of-optimal-perimetric-testing-in-children-optic-development-and-feasibility-of-the-kinetic-perimetry-reliability-measure-kprm
#1
Dipesh E Patel, Ananth C Viswanathan, David Garway-Heath, Phillippa M Cumberland, Bronwen C Walters, Isabelle Russell-Eggitt, Mario Cortina-Borja, Jugnoo S Rahi
INTRODUCTION: Interpretation of perimetric findings, particularly in children, relies on accurate assessment of test reliability, yet no objective measures of reliability exist for kinetic perimetry. We developed the kinetic perimetry reliability measure (KPRM), a quantitative measure of perimetric test reproducibility/reliability and report here its feasibility and association with subjective assessment of reliability. METHODS: Children aged 5-15 years, without an ophthalmic condition that affects the visual field, were recruited from Moorfields Eye Hospital and underwent Goldmann perimetry as part of a wider research programme on perimetry in children...
February 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28092064/critical-congenital-heart-disease-newborn-screening-implementation-lessons-learned
#2
Monica R McClain, John S Hokanson, Regina Grazel, Kim Naarden Van Braun, Lorraine F Garg, Michelle R Morris, Kathleen Moline, Keri Urquhart, Amy Nance, Harper Randall, Marci K Sontag
Introduction The purpose of this article is to present the collective experiences of six federally-funded critical congenital heart disease (CCHD) newborn screening implementation projects to assist federal and state policy makers and public health to implement CCHD screening. Methods A qualitative assessment and summary from six demonstration project grantees and other state representatives involved in the implementation of CCHD screening programs are presented in the following areas: legislation, provider and family education, screening algorithms and interpretation, data collection and quality improvement, telemedicine, home and rural births, and neonatal intensive care unit populations...
January 16, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28087847/addressing-disparities-in-low-back-pain-care-by-developing-culturally-appropriate-information-for-aboriginal-australians-my-back-on-track-my-future
#3
Ivan B Lin, Kim Ryder, Juli Coffin, Charmaine Green, Eric Dalgety, Brian Scott, Leon M Straker, Anne J Smith, Peter B O'Sullivan
OBJECTIVES : Addressing disparities in low back pain care (LBP) is an important yet largely unaddressed issue. One avenue to addressing disparities, recommended by clinical guidelines, is to ensure that LBP information is culturally appropriate. Our objectives were, first, to develop LBP information that was culturally appropriate for Aboriginal Australians living in a rural area and, second, to compare this to traditional information. METHODS : The overall information development process was guided by a "cultural security" framework and included partnerships between Aboriginal/non-Aboriginal investigators, a synthesis of research evidence, and participation of a project steering group consisting of local Aboriginal people...
January 13, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28064027/participation-of-adults-with-visual-and-severe-or-profound-intellectual-disabilities-definition-and-operationalization
#4
Gineke Hanzen, Ruth M A van Nispen, Annette A J van der Putten, Aly Waninge
BACKGROUND: The available opinions regarding participation do not appear to be applicable to adults with visual and severe or profound intellectual disabilities (VSPID). Because a clear definition and operationalization are lacking, it is difficult for support professionals to give meaning to participation for adults with VSPID. AIMS: The purpose of the present study was to develop a definition and operationalization of the concept of participation of adults with VSPID...
January 5, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28060280/a-protocol-of-manual-tests-to-measure-sensation-and-pain-in-humans
#5
Matthew Kostek, Anna Polaski, Benedict Kolber, Austin Ramsey, Alexander Kranjec, Kimberly Szucs
Numerous qualitative and quantitative techniques can be used to test sensory nerves and pain in both research and clinical settings. The current study demonstrates a quantitative sensory testing protocol using techniques to measure tactile sensation and pain threshold for pressure and heat using portable and easily accessed equipment. These techniques and equipment are ideal for new laboratories and clinics where cost is a concern or a limiting factor. We demonstrate measurement techniques for the following: cutaneous mechanical sensitivity on the arms and legs (von-Frey filaments), radiant and contact heat sensitivity (with both threshold and qualitative assessments using the Visual Analog Scale (VAS)), and mechanical pressure sensitivity (algometer, with both threshold and the VAS)...
December 19, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28060004/emerging-technology-for-enhanced-assessment-of-skin-status
#6
Caroline J Borzdynski, William McGuiness, Charne Miller
Pressure injury (PI) prevention has become a key nursing priority that requires clear identification of visual cues representative of PI risk. There is generalized agreement that erythema and skin wetness and/or maceration should be routinely examined by the clinician as part of PI risk assessment. Such an assessment is largely qualitative, deeply reliant on the perception and interpretation of the clinician. Consequently, skin parameters may be misinterpreted, underestimated, or even missed completely. Objective techniques are needed to augment accurate assessment of erythema and skin wetness and/or maceration...
January 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28048842/su-f-r-18-updates-to-the-computational-environment-for-radiological-research-for-image-analysis
#7
Aditya P Apte, Joseph O Deasy
PURPOSE: To present new tools in CERR for Texture Analysis and Visualization. METHOD: (1) Quantitative Image Analysis: We added the ability to compute Haralick texture features based on local neighbourhood. The Texture features depend on many parameters used in their derivation. For example: (a) directionality, (b) quantization of image, (c) patch-size for the neighborhood, (d) handling of the edge voxels within the region of interest, (e) Averaging co-occurance matrix vs texture features for different directions etc...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048385/su-g-brc-07-evaluation-of-aaa-focal-spot-size-for-srs-planning-using-end-to-end-dosimetric-data
#8
S Gardner, A Doemer, B Miller, N Wen, I Chetty
PURPOSE: To use end-to-end dosimetric measurements with Gafchromic film to evaluate the effects of focal spot size parameter for small-field dose calculations using AAA for SRS lesions. METHODS: A total of 13 plans, corresponding to 7 patients previously treated with cranial SRS, were analyzed in this study (target volume range:[0.67cc,13.9cc]). The plans included DCA delivery (4 plans total) and VMAT delivery (9 plans total). All plans were mapped to a solid water phantom (15 cm thickness; isocenter and film plane at 7...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047795/su-f-e-11-perception-and-implementation-of-collaborative-documentation-technologies-among-medical-physics-educators-and-industry-professionals-a-current-practice-survey
#9
Angela N Johnson
PURPOSE: Collaboration on documents and manuscripts plays a central role in conveying medical physics concepts between interdisciplinary teams, necessary for knowledge-building, acquiring funding, and translating scientific concepts to applied medical solutions. Conventional tools and emerging internet-based solutions are used in generating and disseminating physics documents among teams. This research aimed to gain insights on how medical physics professionals and educators are using collaborative documentation software and team practices...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28028922/n-dihydrogalactochitosan-as-a-potent-immune-activator-for-dendritic-cells
#10
Ahmed El-Hussein, Samuel S K Lam, Joseph Raker, Wei R Chen, Michael R Hamblin
Immunotherapy has become one of the fastest growing areas of cancer research. A promising in situ autologous cancer vaccine (inCVAX) uses a novel immune activator, N-dihydrogalactochitosan (GC), that possesses the ability to stimulate dendritic cells (DC). inCVAX is a combination treatment procedure involving treatment of the tumor with a thermal near-infrared laser to liberate whole cell tumor antigens, followed by injection of GC (a glucosamine polymer with galactose attached to the amino groups) into the treated tumor thereby inducing a systemic anti-tumor immune response...
December 28, 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28025338/tbro-visualization-and-management-of-de-novo-transcriptomes
#11
Markus J Ankenbrand, Lorenz Weber, Dirk Becker, Frank Förster, Felix Bemm
RNA sequencing (RNA-seq) has become a powerful tool to understand molecular mechanisms and/or developmental programs. It provides a fast, reliable and cost-effective method to access sets of expressed elements in a qualitative and quantitative manner. Especially for non-model organisms and in absence of a reference genome, RNA-seq data is used to reconstruct and quantify transcriptomes at the same time. Even SNPs, InDels, and alternative splicing events are predicted directly from the data without having a reference genome at hand...
2016: Database: the Journal of Biological Databases and Curation
https://www.readbyqxmd.com/read/28024250/a-novel-combined-approach-of-diffuse-reflectance-uv-vis-nir-spectroscopy-and-multivariate-analysis-for-non-destructive-examination-of-blue-ballpoint-pen-inks-in-forensic-application
#12
Raj Kumar, Vishal Sharma
The present research is focused on the analysis of writing inks using destructive UV-Vis spectroscopy (dissolution of ink by the solvent) and non-destructive diffuse reflectance UV-Vis-NIR spectroscopy along with Chemometrics. Fifty seven samples of blue ballpoint pen inks were analyzed under optimum conditions to determine the differences in spectral features of inks among same and different manufacturers. Normalization was performed on the spectroscopic data before chemometric analysis. Principal Component Analysis (PCA) and K-mean cluster analysis were used on the data to ascertain whether the blue ballpoint pen inks could be differentiated by their UV-Vis/UV-Vis NIR spectra...
December 13, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28018936/noise-performance-of-low-dose-ct-comparison-between-an-energy-integrating-detector-and-a-photon-counting-detector-using-a-whole-body-research-photon-counting-ct-scanner
#13
Zhicong Yu, Shuai Leng, Steffen Kappler, Katharina Hahn, Zhoubo Li, Ahmed F Halaweish, Andre Henning, Cynthia H McCollough
Photon counting detector (PCD)-based computed tomography (CT) is an emerging imaging technique. Compared to conventional energy integrating detector (EID)-based CT, PCD-CT is able to exclude electronic noise that may severely impair image quality at low photon counts. This work focused on comparing the noise performance at low doses between the PCD and EID subsystems of a whole-body research PCD-CT scanner, both qualitatively and quantitatively. An anthropomorphic thorax phantom was scanned, and images of the shoulder portion were reconstructed...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27996374/image-based-quantification-of-plant-immunity-and-disease
#14
Bradley Laflamme, Maggie Middleton, Timothy Lo, Darrell Desveaux, David S Guttman
Measuring the extent and severity of disease is a critical component of plant pathology research and crop breeding. Unfortunately, existing visual scoring systems are qualitative, subjective, and the results are difficult to transfer between research groups, while existing quantitative methods can be quite laborious. Here, we present plant immunity and disease image-based quantification (PIDIQ), a quantitative, semi-automated system to rapidly and objectively measure disease symptoms in a biologically relevant context...
December 2016: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/27981656/the-challenges-of-studying-visual-expertise-in-medical-image-diagnosis
#15
Andreas Gegenfurtner, Ellen Kok, Koos van Geel, Anique de Bruin, Halszka Jarodzka, Adam Szulewski, Jeroen Jg van Merriënboer
CONTEXT: Visual expertise is the superior visual skill shown when executing domain-specific visual tasks. Understanding visual expertise is important in order to understand how the interpretation of medical images may be best learned and taught. In the context of this article, we focus on the visual skill of medical image diagnosis and, more specifically, on the methodological set-ups routinely used in visual expertise research. METHODS: We offer a critique of commonly used methods and propose three challenges for future research to open up new avenues for studying characteristics of visual expertise in medical image diagnosis...
January 2017: Medical Education
https://www.readbyqxmd.com/read/27942154/systematic-review-of-the-effects-of-mirror-therapy-in-children-with-cerebral-palsy
#16
REVIEW
Eom-Ji Park, Soon-Hyung Baek, Soohee Park
[Purpose] To provide data for systematic intervention plans in occupational therapy practice by objectivity showing the value of mirror therapy interventions in children with cerebral palsy. [Subjects and Methods] Medline and EMBASE databases were searched for the key words "cerebral palsy," "mirror movement," "mirror therapy," and "mirror visual feedback." Nine studies that met the inclusion and exclusion criteria were identified. The qualitatively determined level of evidence, period of research, comparisons and interventions, tools used to measure the intervention, and the effects were analyzed...
November 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27936918/post-processing-open-source-software-for-the-cbct-monitoring-of-periapical-lesions-healing-following-endodontic-treatment-technical-report-of-two-cases
#17
Eduardo M Villoria, Antônio R Lenzi, Rodrigo V Soares, Bernardo Q Souki, Asgeir Sigurdsson, Alexandre P Marques, Sandra R Fidel
OBJECTIVES: To describe the use of open-source software for the post-processing of CBCT imaging for the assessment of periapical lesions development after endodontic treatment. METHODS: CBCT scans were retrieved from endodontic records of two patients. Three-dimensional virtual models, voxel counting, volumetric measurement (mm(3)) and mean intensity of the periapical lesion were performed with ITK-SNAP v. 3.0 software. Three-dimensional models of the lesions were aligned and overlapped through the MeshLab software, which performed an automatic recording of the anatomical structures, based on the best fit...
January 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/27928960/research-advances-in-molecular-modeling-in-cyclodextrins
#18
Qianqian Zhao, Weixiang Zhang, Runmiao Wang, Yitao Wang, Defang Ouyang
BACKGROUND: Cyclodextrins (CDs), as one type of the novel pharmaceutical excipients, have been widely used in drug delivery and pharmaceutical industry. Over the past decades, a large amount of molecular modeling studies in CDs were reported for profound understanding of structural, dynamic and energetic features of CDs systems. Thus, this review is focused on qualitative and quantitative analysis of research outputs on molecular modeling in CDs. METHODS: The original data were collected from Web of Science and analyzed by scientific knowledge mapping tools, including Citespace, Science of Science, VOSviewer, GPSvisualizer and Gephi software...
December 8, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27918231/a-3d-assessment-and-feedback-tool-for-ankylosing-spondylitis-from-the-perspective-of-healthcare-professionals
#19
Shijuan Li, Stephen Kay, Stuart Porter
To investigate the utility of 3D visualization technology to augment assessment and feedback for Ankylosing Spondylitis (AS), a visualization prototype was developed, and both subjective and objective measures of current assessment instruments were compared. To verify and establish a base-line for the prototype's effectiveness, motion data and measurement data from a healthy adult in a laboratory environment were collected. To validate the prototype, a qualitative evaluation was undertaken using multiple methods including a pilot study, focus groups, and individual interviews...
December 5, 2016: Informatics for Health & Social Care
https://www.readbyqxmd.com/read/27917244/la-images-a-software-for-elemental-distribution-bioimaging-using-la-icp-ms-data
#20
Hugo López-Fernández, Gustavo de S Pessôa, Marco A Z Arruda, José L Capelo-Martínez, Florentino Fdez-Riverola, Daniel Glez-Peña, Miguel Reboiro-Jato
The spatial distribution of chemical elements in different types of samples is an important field in several research areas such as biology, paleontology or biomedicine, among others. Elemental distribution imaging by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is an effective technique for qualitative and quantitative imaging due to its high spatial resolution and sensitivity. By applying this technique, vast amounts of raw data are generated to obtain high-quality images, essentially making the use of specific LA-ICP-MS imaging software that can process such data absolutely mandatory...
2016: Journal of Cheminformatics
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