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Marion Herens, Annemarie Wagemakers
In community-based health enhancing physical activity (CBHEPA) programmes, group-based principles for action such as active participation, enjoyment, and fostering group processes are widely advocated. However, not much is known about participants' perceptions of these principles as there are no assessment tools available. Therefore, this article describes the development of the APEF (Active Participation, Enjoyment, and Fostering group processes) tool and reports on its implementation in a Dutch CBHEPA programme...
July 4, 2017: Evaluation and Program Planning
Sanda Martinčić-Ipšić, Edvin Močibob, Matjaž Perc
With over 300 million active users, Twitter is among the largest online news and social networking services in existence today. Open access to information on Twitter makes it a valuable source of data for research on social interactions, sentiment analysis, content diffusion, link prediction, and the dynamics behind human collective behaviour in general. Here we use Twitter data to construct co-occurrence language networks based on hashtags and based on all the words in tweets, and we use these networks to study link prediction by means of different methods and evaluation metrics...
2017: PloS One
Ahmad Audi, Marc Pierrot-Deseilligny, Christophe Meynard, Christian Thom
Images acquired with a long exposure time using a camera embedded on UAVs (Unmanned Aerial Vehicles) exhibit motion blur due to the erratic movements of the UAV. The aim of the present work is to be able to acquire several images with a short exposure time and use an image processing algorithm to produce a stacked image with an equivalent long exposure time. Our method is based on the feature point image registration technique. The algorithm is implemented on the light-weight IGN (Institut national de l'information géographique) camera, which has an IMU (Inertial Measurement Unit) sensor and an SoC (System on Chip)/FPGA (Field-Programmable Gate Array)...
July 18, 2017: Sensors
Arnab Pal, C Dhana Sekhar, Adyam Venimadhav, Pattukkannu Murugavel
The evolution of various magnetic ordering has been studied for orthorhombic perovskite GdMn<sub>1-<i>x</i></sub>Fe<sub><i>x</i></sub>O<sub>3</sub> (0 ≤ <i>x</i> ≤ 0.7) system to get its comprehensive magnetic phase diagram. We observed that the substitution of Fe in GdMnO<sub>3</sub> increases the antiferromagnetic Neel temperature (T<sub>N</sub>) from 40 K to above 400 K and importantly induces a spin-reorientation transition (T<sub>SR</sub>) for <i>x</i> ≥ 0...
July 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Ujwala A Shinde, Sheela H Modani, Kavita H Singh
Microemulsion formulation of repaglinide, a BCS class II hypoglycemic agent with limited oral bioavailability, was developed considering its solubility in various oils, surfactants, and cosurfactants. The pseudo-ternary phase diagrams for microemulsion regions were constructed by water titration method at K m 1:1 and characterized for optical birefringence, percentage transmittance, pH, refractive index, globule size, zeta potential, viscosity, drug content, and thermodynamic stability. To enhance the drug permeation and residence time, the optimized microemulsions having mean globule size of 36...
July 17, 2017: AAPS PharmSciTech
Ombretta Paladino, Arianna Moranda, Marco Massabò, Gary A Robbins
Despite the availability of numerical models, interest in analytical solutions of multidimensional advection-dispersion systems remains high. Such models are commonly used for performing Tier I risk analysis and are embedded in many regulatory frameworks dealing with groundwater contamination. In this work, we develop a closed-form solution of the three-dimensional advection-dispersion equation with exponential source decay, first-order reaction, and retardation, and present an approach based on some ease of use diagrams to compare it with the integral open form solution and with earlier versions of the closed-form solution...
July 17, 2017: Ground Water
Guangda Xin, Guangyu Zhou, Xiaofei Zhang, Wanning Wang
The aim of the present study was to identify candidate microRNAs (miRNAs) involved in the progression of renal fibrosis. Dataset GSE42716 of miRNAs extracted from kidneys from mice with unilateral ureteral obstruction (UUO), and mice without UUO was downloaded from the Gene Expression Omnibus database. The Limma package was used to identify differential expression between mice with and without UUO. Renal disease‑related miRNAs were predicted based on the miRWalk database. Thereafter, candidate miRNAs were screened by taking the intersection of differentially expressed miRNAs and predicted miRNAs, followed by screening of target genes using miRWalk and transcription factors using the TransmiR database...
July 5, 2017: Molecular Medicine Reports
Abhijit Guha, Kaustav Pradhan
A major aim of the present work is to understand and thoroughly document the generation, the three-dimensional distribution, and the evolution of the secondary motion as the fluid progresses downstream through a branched network. Six generations (G0-G5) of branches (involving 63 straight portions and 31 bifurcation modules) are computed in one go; such computational challenges are rarely taken in the literature. More than 30 × 10(6) computational elements are employed for high precision of computed results and fine quality of the flow visualization diagrams...
June 2017: Physics of Fluids
Lilian Sosa, Beatriz Clares, Helen L Alvarado, Nuria Bozal, Oscar Domenech, Ana C Calpena
The present study was designed to develop a nanoemulsion formulation of Amphotericin B (AmB) for the treatment of skin candidiasis and aspergillosis. Several ingredients were selected on the basis of AmB solubility and compatibility with skin. The formulation that exhibited the best properties was selected from the pseudo-ternary phase diagram. After physicochemical characterization its stability was assessed. Drug release and skin permeation studies were also accomplished. The antifungal efficacy and skin tolerability of developed AmB nanoemulsion was demonstrated...
July 13, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
Vedrana Savić, Marija Todosijević, Tanja Ilić, Milica Lukić, Evgenia Mitsou, Vassiliki Papadimitriou, Spyridon Avramiotis, Bojan Marković, Nebojša Cekić, Snežana Savić
In order to improve skin penetration of tacrolimus we aimed to develop potentially non-irritant, lecithin-based microemulsions containing ethanol, isopropanol and/or propylene glycol as cosurfactants, varying caprylic/capric triglycerides and propylene glycol monocaprylate as oil phase. The influence of excipients on the size of microemulsion region in pseudo-ternary phase diagrams and their ability to form different types of microemulsions was evaluated. The comprehensive physicochemical characterization of microemulsions and the evaluation of their structure was performed, while the localization of tacrolimus in microemulsions was further investigated using electron paramagnetic resonance spectroscopy...
July 12, 2017: International Journal of Pharmaceutics
Matthew J Williams, Michael Bachmann
The formation of tertiary structures made up of helical polymer segments is influenced by the introduction of an attractive substrate onto which the polymer can adsorb. We perform replica-exchange Monte Carlo simulations to study the formation of helical structures in the vicinity of an attractive generic substrate by means of a coarse-grained hybrid model and compare the structural phase space for both adsorbed and free helical polymers. We introduce suitable structural order parameters to understand the features of distinct structural phases...
July 14, 2017: Journal of Chemical Physics
Jiatao Zhu, Shiliang Mei, Wu Yang, Guilin Zhang, Qiuhang Chen, Wanlu Zhang, Ruiqian Guo
In this work, transition metal ion- doped zinc-based quantum dots (QDs) are synthesized via a greener controllable method to avoid the toxicity of the traditional cadmium-based QDs and broaden the tunable emission. Herein, the tunable emission of Cu-doped ZnInS/ZnS core-shell QDs (Cu:ZnInS/ZnS) can cover from 500 to 620nm by varying the Cu dopant concentration from 1 to 20% and the maximum quantum yield can reach 49.8%. Based on the single-doped QDs, Cu,Mn co-doped ZnInS/ZnS core-shell QDs (Cu,Mn:ZnInS/ZnS) with a photoluminance (PL) quantum yield of 30...
June 15, 2017: Journal of Colloid and Interface Science
Nevenka Bihari
Flow cytometry is a convenient method for the determination of genotoxic effects of environmental pollution and can reveal genotoxic compounds in unknown environmental mixtures. It is especially suitable for the analyses of large numbers of samples during monitoring programs. The speed of detection is one of the advantages of this technique which permits the acquisition of 10(4)-10(5) cells per sample in 5 min. This method can rapidly detect cell cycle alterations resulting from DNA damage. The outcome of such an analysis is a diagram of DNA content across the cell cycle which indicates cell proliferation, G2 arrests, G1 delays, apoptosis, and ploidy...
2017: Methods in Molecular Biology
T Sari, M J Wade
The complexity of the anaerobic digestion process has motivated the development of complex models, such as the widely used Anaerobic Digestion Model No. 1. However, this complexity makes it intractable to identify the stability profile coupled to the asymptotic behaviour of existing steady-states as a function of conventional chemostat operating parameters (substrate inflow concentration and dilution rate). In a previous study this model was simplified and reduced to its very backbone to describe a three-tiered chlorophenol mineralising food-web, with its stability analysed numerically using consensus values for the various biological parameters of the Monod growth functions...
July 11, 2017: Mathematical Biosciences
Xiangyu Cao, Alberto Rosso, Jean-Philippe Bouchaud, Pierre Le Doussal
We introduce and study a banded random matrix model describing sparse, long-range quantum hopping in one dimension. Using a series of analytic arguments, numerical simulations, and a mapping to a long-range epidemics model, we establish the phase diagram of the model. A genuine localization transition, with well defined mobility edges, appears as the hopping rate decreases slower than ℓ^{-2}, where ℓ is the distance. Correspondingly, the decay of the localized states evolves from a standard exponential shape to a stretched exponential and finally to a exp(-Cln^{κ}ℓ) behavior, with κ>1...
June 2017: Physical Review. E
N Shankaraiah
We use protein folding energy landscape concepts such as golf course and funnel to study re-equilibration in athermal martensites under systematic temperature quench Monte Carlo simulations. On quenching below a transition temperature, the seeded high-symmetry parent-phase austenite that converts to the low-symmetry product-phase martensite, through autocatalytic twinning or elastic photocopying, has both rapid conversions and incubation delays in the temperature-time-transformation phase diagram. We find the rapid (incubation delays) conversions at low (high) temperatures arises from the presence of large (small) size of golf-course edge that has the funnel inside for negative energy states...
June 2017: Physical Review. E
Kevin Roth, Flaviano Morone, Byungjoon Min, Hernán A Makse
A model of interdependent networks of networks (NONs) was introduced recently [Proc. Natl. Acad. Sci. (USA) 114, 3849 (2017)PNASA60027-842410.1073/pnas.1620808114] in the context of brain activation to identify the neural collective influencers in the brain NON. Here we investigate the emergence of robustness in such a model, and we develop an approach to derive an exact expression for the random percolation transition in Erdös-Rényi NONs of this kind. Analytical calculations are in agreement with numerical simulations, and highlight the robustness of the NON against random node failures, which thus presents a new robust universality class of NONs...
June 2017: Physical Review. E
Bhavya Mishra, Debashish Chowdhury
We develop a two-species exclusion process with a distinct pair of entry and exit sites for each species of rigid rods. The relatively slower forward stepping of the rods in an extended bottleneck region, located in between the two entry sites, controls the extent of interference of the codirectional flow of the two species of rods. The relative positions of the sites of entry of the two species of rods with respect to the location of the bottleneck are motivated by a biological phenomenon. However, the primary focus of the study here is to explore the effects of the interference of the flow of the two species of rods on their spatiotemporal organization and the regulations of this interference by the extended bottleneck...
June 2017: Physical Review. E
J M Luck, A Mehta
We investigate how leaders emerge as a consequence of the competitive dynamics between coupled papers in a model citation network. Every paper is allocated an initial fitness depending on its intrinsic quality. Its fitness then involves dynamically as a consequence of the competition between itself and all the other papers in the field. It picks up citations as a result of this adaptive dynamics, becoming a leader if it has the highest citation count at a given time. Extensive analytical and numerical investigations of this model suggest the existence of a universal phase diagram, divided into regions of weak and strong coupling...
June 2017: Physical Review. E
J L B de Araújo, F F Munarin, G A Farias, F M Peeters, W P Ferreira
Two-dimensional systems of inverse patchy colloids modeled as disks with a central charge and having their surface decorated with oppositely pointlike charged patches are investigated using molecular dynamics simulations. The self-assembly of the patchy colloids leads to diverse ground state configurations ranging from crystalline arrangements of monomers to linear clusters, ramified linear clusters and to percolated configurations. Two structural phase diagrams are constructed: (1) as a function of the net charge and area fraction, and (2) as a function of the net charge and the range of the pair interaction potential...
June 2017: Physical Review. E
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