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JOURNAL ARTICLE
Alessandro Girombelli, Francesco Vetrone, Francesco Saglietti, Andrea Galimberti, Andrea Fusaro, Michele Umbrello, Angelo Pezzi
BACKGROUND: Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and early discharge. Fascia iliaca compartment block (FICB) has been recommended since it offers good pain control with a low risk of motor block. Pericapsular nerve group (PENG) block with lateral femoral cutaneous block (LFCN) has been proposed as an effective alternative to FICB that offers better pain control with a considerably lower risk of motor block. We aimed to compare the aforementioned blocks and determine which one yielded the lowest numeric rating scale (NRS) score...
2024: Saudi Journal of Anaesthesia
#2
Kay E Davies, Julie Vogt
Duchenne muscular dystrophy is a neuromuscular disease caused by DMD gene mutations that result in an absence of functional dystrophin protein. Patients with Duchenne experience progressive muscle weakness, are typically wheelchair dependent by their early teens, and develop respiratory and cardiac complications that lead to death in their twenties or thirties. Becker muscular dystrophy is also caused by DMD gene mutations, but symptoms are less severe and progression is slower compared with Duchenne. We describe a case study of a patient with Becker muscular dystrophy who was still ambulant at age 61 years and had a milder phenotype than Duchenne, despite 46% of his DMD gene being missing...
April 14, 2024: Neuromuscular Disorders: NMD
#3
REVIEW
Marta Cucchi, Silvia Mariani, Michal J Kawczynski, Emma Shkurka, Fabio Ius, Giuseppe Comentale, Aparna Hoskote, Roberto Lorusso
OBJECTIVE: Awake Extracorporeal Life Support (aECLS) with active mobilization has gained consensus over time, also within the pediatric community. This individual patient data (IPD) meta-analysis summarizes available evidence on pediatric aECLS, its feasibility, and safety regarding sedation weaning, extubation, and physiotherapy. METHODS: PubMed/Medline and Cochrane Database were screened until February 2022. Articles reporting on children (≤18 years) undergoing aECLS were selected...
April 23, 2024: Perfusion
#4
Kaiho Hirata, Takuyo Chiba, Harumi Gomi, Saho Takaya, Yasuyuki Kato, Takashi Shiga
Dengue is a systemic viral infection, and clinical findings vary from asymptomatic to life-threatening, including shock and neurological complications. Despite efforts in vector control, the disease continues to spread worldwide, and the number of annual dengue infections is estimated to be 390 million. For patients with severe dengue, early diagnosis is important; however, owing to the wide range of symptoms and severity, diagnosis can be difficult. Herein, we report the case of a 24-year-old man from Vietnam who was found to have dengue shock syndrome complicated by meningoencephalitis, even though he did not show the typical clinical manifestations of dengue infection...
2024: IDCases
#5
JOURNAL ARTICLE
Xiaobing Li, Jing Bai, Xin Guo, Yaqian Mu, Zhengli Di, Gejuan Zhang, Bo Wang, Yun Zhang, Xinyao Liu, Yan Shi, Shinuan Lin, Linyu Wu, Ya Bai, Xuedong Liu
BACKGROUND: Multiple system atrophy (MSA) is a disease with diverse symptoms and the commonly used classifications, MSA-P and MSA-C, do not cover all the different symptoms seen in MSA patients. Additionally, these classifications do not provide information about how the disease progresses over time or the expected outcome for patients. OBJECTIVE: To explore clinical subtypes of MSA with a natural disease course through a data-driven approach to assist in the diagnosis and treatment of MSA...
April 12, 2024: Journal of Parkinson's Disease
#6
JOURNAL ARTICLE
Agnieszka Sobierajska-Rek, Joanna Jabłońska-Brudło, Aneta Dąbrowska, Wiktoria Wojnicz, Jarosław Meyer-Szary, Jolanta Wierzba
BACKGROUND: Functional activities are extensively used in motor assessments of patients with Duchenne muscular dystrophy. The role of timed items has been reported as an early prognostic factor for disease progression. However, there are two functional activities that are not widely assessed in clinical practice among Duchenne muscular dystrophy patients: rolling and bed rising. This study aimed to investigate whether the 360-degree roll (roll) and supine to sit-to-edge (bed rise) measurements are feasible tools reflecting the functional status of ambulatory DMD children by establishing possible correlations between validated measures: the Vignos Scale (VS), timed rise from floor and the 6-Minute Walk Test (6MWT)...
April 2024: Minerva pediatrics
#7
JOURNAL ARTICLE
Peter G Passias, Peter S Tretiakov, Oluwatobi O Onafowokan, Matthew Galetta, Nathan Lorentz, Jamshaid M Mir, Ankita Das, Pooja Dave, Renaud Lafage, Timothy Yee, Bassel Diebo, Shaleen Vira, Pawel P Jankowski, Aaron Hockley, Alan Daniels, Andrew J Schoenfeld, Praveen Mummaneni, Carl B Paulino, Virginie Lafage
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To investigate the impact of evolving Enhanced Recovery After Surgery (ERAS) protocols on outcomes after cervical deformity (CD) surgery. BACKGROUND: ERAS can help accelerate patient recovery and assist hospitals in maximizing the incentives of bundled payment models while maintaining high-quality patient care. However, there remains a paucity of literature assessing how developments have impacted outcomes after adult CD surgery...
April 9, 2024: Clinical Spine Surgery
#8
JOURNAL ARTICLE
Marika Pane, Giulia Stanca, Chiara Ticci, Costanza Cutrona, Roberto De Sanctis, Matteo Pirinu, Giorgia Coratti, Concetta Palermo, Beatrice Berti, Daniela Leone, Michele Sacchini, Margherita Cerboneschi, Lavinia Fanelli, Giulia Norcia, Nicola Forcina, Anna Capasso, Gianpaolo Cicala, Laura Antonaci, Martina Ricci, Maria Carmela Pera, Chiara Bravetti, Maria Alice Donati, Elena Procopio, Emanuela Abiusi, Alessandro Vaisfeld, Roberta Onesimo, Francesco Danilo Tiziano, Eugenio Mercuri
Neonatal screening for SMA has allowed the identification of infants who may present with early clinical signs. Our aim was to establish whether the presence and the severity of early clinical signs have an effect on the development of motor milestones. Infants identified through newborn screening were prospectively assessed using a structured neonatal neurological examination and an additional module developed for the assessment of floppy infants. As part of the follow-up, all infants were assessed using the HINE-2 to establish developmental milestones...
April 18, 2024: European Journal of Pediatrics
#9
JOURNAL ARTICLE
Paul J Braybrook, Hideo Tohira, Deon Brink, Judith Finn, Peter L Buzzacott
INTRODUCTION: Outdoor activities offer physical and mental health benefits. However, incidents can occur requiring ambulance transport to hospital. This study aimed to describe the epidemiology and severity of traumatic and medical incidents for mountain bikers and hikers transported by ambulance within Western Australia. METHODS: This was a retrospective cohort study of ambulance-transported mountain bikers and hikers within Western Australia from 2015 to 2020...
April 18, 2024: Wilderness & Environmental Medicine
#10
JOURNAL ARTICLE
Artit Laoruengthana, Kongpob Reosanguanwong, Piti Rattanaprichavej, Kamonnop Sahasoonthorn, Nopparat Santisathaporn, Krit Pongpirul
BACKGROUND: Cruciate-retaining (CR) total knee arthroplasty (TKA) may provide better physiological knee kinematics, proprioception, and quadricep recovery than posterior-stabilized (PS) TKA. Therefore, we hypothesized that CR TKA with multimodal pain control may provide comparable postoperative pain and recovery as unicompartmental knee arthroplasty (UKA). METHODS: This study included patients with isolated medial compartment knee osteoarthritis who underwent CR TKA and UKA...
2024: Orthopedic Research and Reviews
#11
JOURNAL ARTICLE
Victoria Woodcroft-Brown, Jack Bell, Chrysanth Ranjeev Pulle, Rebecca Mitchell, Jacqueline Close, Catherine McDougall, Sarah Hurring, Mitchell Sarkies
OBJECTIVES: To examine patient, surgical and hospital factors associated with Day-1 postoperative mobility after hip fracture surgery in older adults. METHODS: A cohort study using Australia and New Zealand Hip Fracture Registry was conducted. Participants were aged older than 50 years and underwent hip fracture surgery between 1 January 2020 and 31 December 2020 inclusive. The outcome was standing and step transferring out of bed onto a chair and/or walking Day-1 after hip fracture surgery...
April 14, 2024: Australasian Journal on Ageing
#12
Shan Kai Ing, Grace Wan Chieng Lee, Tze Shin Leong, Yih Hoong Lee, George Yew Liang Lau, Nur Nazihah Yusof, Andrew Kean Wei Chang, Kelly Kee Yung Wong
Tuberculosis-associated hemophagocytic lymphohistiocytosis (TB-HLH) is a rare and life-threatening complication of tuberculosis infection. Early recognition and treatment of TB-HLH is crucial for improving outcomes. Treatment typically involves a combination of antituberculosis therapy and immunosuppressive therapy to control the immune system's overreaction. In this report, we present the case of a 53-year-old ambulance driver who was diagnosed with TB-HLH. His CT scan revealed splenic abscesses, hepatomegaly and bilateral lung consolidation...
July 2023: Clinical Medicine: Journal of the Royal College of Physicians of London
#13
MULTICENTER STUDY
Laura Melero Guijarro, Francisco Martín-Rodríguez, Jesús Álvarez Manzanares, Carlos Del Pozo Vegas, Ancor Sanz García, Miguel Ángel Castro Villamor, Raúl López-Izquierdo
OBJECTIVES: To develop and validate a risk model for 1-year mortality based on variables available from early prehospital emergency attendance of patients with infection. MATERIAL AND METHODS: Prospective, observational, noninterventional multicenter study in adults with suspected infection transferred to 4 Spanish hospitals by advanced life-support ambulances from June 1, 2020, through June 30, 2022. We collected demographic, physiological, clinical, and analytical data...
April 2024: Emergencias: Revista de la Sociedad Española de Medicina de Emergencias
#14
JOURNAL ARTICLE
Takahito Kondo, Hiroyuki Tsuboi, Kazunari Nishiyama, Gaku Takahashi, Yukihide Nishimura
Rehabilitation treatments for patients with severe burn injury (SBI) are difficult owing to the lack of knowledge, skills, and experience among clinicians and physical and occupational therapists, resulting in serious patient disability. This study retrospectively evaluated the effectiveness of rehabilitation treatments jointly considered by physiatrists and rehabilitation therapists (Physiatrist and Registered therapist Operating rehabilitation: PROr) for patients with SBI admitted to our hospital's burn intensive care unit (BICU)...
April 4, 2024: Burns
#15
JOURNAL ARTICLE
Sarah Sabbatini, Sai R Velamuri, David M Hill
Cultured epidermal autografts (CEA) have since become more prevalent in the treatment of burn-injured patients with limited available donor sites for adequate wound closure, resulting in decreased mortality rates and an increased number of these patients requiring burn therapy services to achieve optimal functional outcomes at discharge. However, the use and postoperative management of CEA continues to be controversial due in large to the physiological fragility and expense of CEA, leading to variable postoperative treatment practices across burn centers...
April 11, 2024: Journal of Burn Care & Research: Official Publication of the American Burn Association
#16
JOURNAL ARTICLE
Ahmad A Abujaber, Ibrahem Albalkhi, Yahia Imam, Abdulqadir Nashwan, Naveed Akhtar, Ibraheem M Alkhawaldeh
OBJECTIVES: Predicting stroke mortality is crucial for personalized care. This study aims to design and evaluate a machine learning model to predict one-year mortality after a stroke. MATERIALS AND METHODS: Data from the National Multiethnic Stroke Registry was utilized. Eight machine learning (ML) models were trained and evaluated using various metrics. SHapley Additive exPlanations (SHAP) analysis was used to identify the influential predictors. RESULTS: The final analysis included 9840 patients diagnosed with stroke were included in the study...
April 15, 2024: Heliyon
#17
JOURNAL ARTICLE
Oliver Schwartz, Katharina Vill, Michelle Pfaffenlehner, Max Behrens, Claudia Weiß, Jessika Johannsen, Johannes Friese, Andreas Hahn, Andreas Ziegler, Sabine Illsinger, Martin Smitka, Arpad von Moers, Heike Kölbel, Gudrun Schreiber, Nadja Kaiser, Ekkehard Wilichowski, Marina Flotats-Bastardas, Ralf A Husain, Matthias Baumann, Cornelia Köhler, Regina Trollmann, Annette Schwerin-Nagel, Astrid Eisenkölbl, Mareike Schimmel, Martin Fleger, Birgit Kauffmann, Gert Wiegand, Manuela Baumgartner, Christian Rauscher, Sebahattin Cirak, Dieter Gläser, Günther Bernert, Tim Hagenacker, Susanne Goldbach, Kristina Probst-Schendzielorz, Hanns Lochmüller, Wolfgang Müller-Felber, Ulrike Schara-Schmidt, Maggie C Walter, Janbernd Kirschner, Astrid Pechmann
IMPORTANCE: There is increasing evidence that early diagnosis and treatment are key for outcomes in infants with spinal muscular atrophy (SMA), and newborn screening programs have been implemented to detect the disease before onset of symptoms. However, data from controlled studies that reliably confirm the benefits of newborn screening are lacking. OBJECTIVE: To compare data obtained on patients with SMA diagnosed through newborn screening and those diagnosed after clinical symptom onset...
April 8, 2024: JAMA Pediatrics
#18
JOURNAL ARTICLE
Flora D'Ambrosio, Michael Harbo, Danilo Contiero, Anna Rita Bonfigli, Diletta Cicconi, Niels Heuer, Arend Roos, Christian Fischer Pedersen, Paolo Fabbietti, Cristina Gagliardi
INTRODUCTION: Falls are a major worldwide health problem in older people. Several physical rehabilitation programs with home-based technologies, such as the online DigiRehab platform, have been successfully delivered. The PRECISE project combines personalized training delivered through the application with an artificial intelligence-based predictive model (AI-DSS platform) for fall risk assessment. This new system, called DigiRehab, will enable early identification of significant risk factors for falling and propose an individualized physical training plan to attend to these critical areas...
2024: Frontiers in Public Health
#19
JOURNAL ARTICLE
Yu-Ting Zhu, Yu-Xin Jiang, Lei Pei, Wei-Chao Zhu, Xiao-Guo Jin
BACKGROUND: The quality control circle (QCC) model has achieved good results in clinical applications in many hospitals in China and has gained popularity. This study aims to explore the application of QCC activities on early ambulation after cesarean section. METHODS: A QCC management group was established following standardized methods and techniques. The theme of the group was identified as "to enhance the implementation rate of the patient early ambulation after the cesarean section" through a matrix graph...
April 5, 2024: Medicine (Baltimore)
#20
JOURNAL ARTICLE
Mei Sing Quek, Chien Wei Oei, Poo Lee Ong, Chloe Lau Ha Chung, Pui Wah Kong, Xiaojin Zhang, Kee Hao Leo
OBJECTIVE: To formulate a prognostication model in the early post-operation phase of lower limb amputation to predict patient's ability to ambulate with a prosthesis post rehabilitation. DESIGN: Retrospective cohort study, using data collected from electronic medical records. Predictive factors and prosthetic ambulation outcomes post rehabilitation were used to develop prognostic models via machine learning techniques. SETTING: Regional hospital's ambulatory rehabilitation clinic...
April 1, 2024: Archives of Physical Medicine and Rehabilitation
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